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Volumn 115, Issue 3, 2005, Pages 739-746

Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYCYTIDYL DEOXYGUANOSIN OLIGODEOXYNUCLEOTIDE; FREUND ADJUVANT; GAMMA INTERFERON; GRANZYME B; HLA A2 ANTIGEN; MELAN A; OLIGONUCLEOTIDE; PERFORIN; TOLL LIKE RECEPTOR 9; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 14644390867     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI23373     Document Type: Article
Times cited : (593)

References (51)
  • 1
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • Janeway, C.A., Jr. 1989. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54:1-13.
    • (1989) Cold Spring Harb. Symp. Quant. Biol. , vol.54 , pp. 1-13
    • Janeway Jr., C.A.1
  • 2
    • 0028117165 scopus 로고
    • Subversion of the immune system by pathogens
    • Marrack, P., and Kappler, J. 1994. Subversion of the immune system by pathogens. Cell 76:323-332.
    • (1994) Cell , vol.76 , pp. 323-332
    • Marrack, P.1    Kappler, J.2
  • 3
    • 0031050034 scopus 로고    scopus 로고
    • Innate immunity: Impact on the adaptive immune response
    • Medzhitov, R., and Janeway, C.A., Jr. 1997. Innate immunity: impact on the adaptive immune response. Curr. Opin. Immunol. 9:4-9.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 4-9
    • Medzhitov, R.1    Janeway Jr., C.A.2
  • 4
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • Akira, S., Takeda, K., and Kaisho, T. 2001. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2:675-680.
    • (2001) Nat. Immunol. , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 5
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of human dendritic cell precursors express different toll-like recepcors and respond to different microbial antigens
    • Kadowaki, N., et al. 2001. Subsets of human dendritic cell precursors express different toll-like recepcors and respond to different microbial antigens. J. Exp. Med. 194:863-869.
    • (2001) J. Exp. Med. , vol.194 , pp. 863-869
    • Kadowaki, N.1
  • 6
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • Steinman, R.M. 1991. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9:271-296.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 271-296
    • Steinman, R.M.1
  • 7
    • 1842631153 scopus 로고    scopus 로고
    • Immunotherapeutic uses of CpG oligodeoxynucleotides
    • Klinman, D.M. 2004. Immunotherapeutic uses of CpG oligodeoxynucleotides. Nat. Rev. Immunol. 4:249-259.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 249-259
    • Klinman, D.M.1
  • 8
    • 0034619794 scopus 로고    scopus 로고
    • A Toll-like receptor recognizes bacterial DNA
    • Hemmi, H., et al. 2000. A Toll-like receptor recognizes bacterial DNA. Nature. 408:740-745.
    • (2000) Nature , vol.408 , pp. 740-745
    • Hemmi, H.1
  • 9
    • 0035477969 scopus 로고    scopus 로고
    • Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells
    • Takeshita, F., et al. 2001. Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells. J. Immunol. 167:3555-3558.
    • (2001) J. Immunol. , vol.167 , pp. 3555-3558
    • Takeshita, F.1
  • 10
    • 0030955249 scopus 로고    scopus 로고
    • Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization
    • Weiner, G.J., Liu, H.M., Wooldridge, J.E., Dahle, C.E., and Krieg, A.M. 1997. Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization. Proc. Natl. Acad. Sci. U. S. A. 94:10833-10837.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 10833-10837
    • Weiner, G.J.1    Liu, H.M.2    Wooldridge, J.E.3    Dahle, C.E.4    Krieg, A.M.5
  • 11
    • 0030850462 scopus 로고    scopus 로고
    • CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: A new class of vaccine adjuvants
    • Lipford, G.B., et al. 1997. CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants. Eur. J. Immunol. 27:2340-2344.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2340-2344
    • Lipford, G.B.1
  • 12
    • 0032921241 scopus 로고    scopus 로고
    • CpG-containing oligonucleotides are efficient adjuvants for induction of protective antiviral immune responses with T-cell peptide vaccines
    • Oxenius, A., Martinic, M.M., Hengartner, H., and Klenerman, P. 1999. CpG-containing oligonucleotides are efficient adjuvants for induction of protective antiviral immune responses with T-cell peptide vaccines. J. Virol. 73:4120-4126.
    • (1999) J. Virol. , vol.73 , pp. 4120-4126
    • Oxenius, A.1    Martinic, M.M.2    Hengartner, H.3    Klenerman, P.4
  • 13
    • 0034163408 scopus 로고    scopus 로고
    • CpG-DNA activates in vivo T cell epitope presenting dendritic cells to trigger protective antiviral cytotoxic T cell responses
    • Vabulas, R.M., Pircher, H., Lipford, G.B., Hacker, H., and Wagner, H. 2000. CpG-DNA activates in vivo T cell epitope presenting dendritic cells to trigger protective antiviral cytotoxic T cell responses. J. Immunol. 164:2372-2378.
    • (2000) J. Immunol. , vol.164 , pp. 2372-2378
    • Vabulas, R.M.1    Pircher, H.2    Lipford, G.B.3    Hacker, H.4    Wagner, H.5
  • 14
    • 0034235701 scopus 로고    scopus 로고
    • Repeated administration of cytosine-phosphorothiolated guanine-containing oligonucleotides together with peptide/ protein immunizacion results in enhanced CTL responses with anti-tumor activity
    • Davila, E., and Celis, E. 2000. Repeated administration of cytosine-phosphorothiolated guanine-containing oligonucleotides together with peptide/ protein immunizacion results in enhanced CTL responses with anti-tumor activity. J. Immunol. 165:539-547.
    • (2000) J. Immunol. , vol.165 , pp. 539-547
    • Davila, E.1    Celis, E.2
  • 15
    • 0036467426 scopus 로고    scopus 로고
    • CpG are efficient adjuvants for specific CTL induction against tumor antigen-derived peptide
    • Miconnet, I., et al. 2002. CpG are efficient adjuvants for specific CTL induction against tumor antigen-derived peptide. J. Immunol. 168:1212-1218.
    • (2002) J. Immunol. , vol.168 , pp. 1212-1218
    • Miconnet, I.1
  • 16
    • 0034142182 scopus 로고    scopus 로고
    • Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo
    • Hartmann, G., et al. 2000. Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo. J. Immunol. 164:1617-1624.
    • (2000) J. Immunol. , vol.164 , pp. 1617-1624
    • Hartmann, G.1
  • 17
    • 0035979192 scopus 로고    scopus 로고
    • Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
    • Bauer, S., et al. 2001. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition. Proc. Natl. Acad. Sci. U. S. A. 98:9237-9242.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 9237-9242
    • Bauer, S.1
  • 18
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg, A.M. 2002. CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol. 20:709-760.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 709-760
    • Krieg, A.M.1
  • 19
    • 17944402906 scopus 로고    scopus 로고
    • CpG DNA overcomes hyporesponsiveness to hepatitis B vaccine in orangutans
    • Davis, H.L., et al. 2000. CpG DNA overcomes hyporesponsiveness to hepatitis B vaccine in orangutans. Vaccine. 18:1920-1924.
    • (2000) Vaccine , vol.18 , pp. 1920-1924
    • Davis, H.L.1
  • 20
    • 0037726807 scopus 로고    scopus 로고
    • A phase I study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant
    • Halperin, S.A., et al. 2003. A phase I study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant. Vaccine. 21:2461-2467.
    • (2003) Vaccine , vol.21 , pp. 2461-2467
    • Halperin, S.A.1
  • 21
    • 0030996710 scopus 로고    scopus 로고
    • Enhancement of cellular immunity in melanoma patients immunized with a peptide from MART-1/Melan A
    • Cormier, J.N., et al. 1997. Enhancement of cellular immunity in melanoma patients immunized with a peptide from MART-1/Melan A. Cancer J. Sci. Am. 3:37-44.
    • (1997) Cancer J. Sci. Am. , vol.3 , pp. 37-44
    • Cormier, J.N.1
  • 22
    • 0037390262 scopus 로고    scopus 로고
    • A phase I trial of SD-9427 (progenipoietin) with a multipeptide vaccine for resected metastatic melanoma
    • Pullarkat, V., et al. 2003. A phase I trial of SD-9427 (progenipoietin) with a multipeptide vaccine for resected metastatic melanoma. Clin. Cancer Res. 9:1301-1312.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1301-1312
    • Pullarkat, V.1
  • 23
    • 13444249836 scopus 로고    scopus 로고
    • Ex vivo detectable activation of Melan-A specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA
    • Liénard, D., et al. 2004. Ex vivo detectable activation of Melan-A specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA. Cancer Immunity. 4:4.
    • (2004) Cancer Immunity , vol.4 , pp. 4
    • Liénard, D.1
  • 24
    • 0031890206 scopus 로고    scopus 로고
    • Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
    • Rosenberg, S.A., et al. 1998. Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nat. Med. 4:321-327.
    • (1998) Nat. Med. , vol.4 , pp. 321-327
    • Rosenberg, S.A.1
  • 25
    • 0036094530 scopus 로고    scopus 로고
    • T-cell responses against tyrosinase 368-376(370D) peptide in HLA*A0201+ melanoma patients: Randomized trial comparing incomplete Freund's adjuvant, granulocyte macrophage colony-stimulating factor, and QS-21 as immunological adjuvants
    • Schaed, S.G., et al. 2002. T-cell responses against tyrosinase 368-376(370D) peptide in HLA*A0201+ melanoma patients: randomized trial comparing incomplete Freund's adjuvant, granulocyte macrophage colony-stimulating factor, and QS-21 as immunological adjuvants. Clin. Cancer Res. 8:967-972.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 967-972
    • Schaed, S.G.1
  • 26
    • 3042541542 scopus 로고    scopus 로고
    • Disease-driven T cell activation predicts immune responses to vaccination against melanoma
    • Speiser, D.E., et al. 2003. Disease-driven T cell activation predicts immune responses to vaccination against melanoma. Cancer Immunity. 3:12.
    • (2003) Cancer Immunity , vol.3 , pp. 12
    • Speiser, D.E.1
  • 27
    • 3042693359 scopus 로고    scopus 로고
    • Ex vivo analysis of human antigen specific CD8+ T cell responses: Quality assessment of fluorescent HLA-A2 multimers and IFN gamma Elispot assays for patient immune monitoring
    • Speiser, D.E., et al. 2004. Ex vivo analysis of human antigen specific CD8+ T cell responses: Quality assessment of fluorescent HLA-A2 multimers and IFN gamma Elispot assays for patient immune monitoring. J. Immunother. 27:298-308.
    • (2004) J. Immunother. , vol.27 , pp. 298-308
    • Speiser, D.E.1
  • 28
    • 0026068601 scopus 로고
    • Programmed cell death and extrathymic reduction of Vβ8+ CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B
    • Kawabe, Y., and Ochi, A. 1991. Programmed cell death and extrathymic reduction of Vβ8+ CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B. Nature. 349:245-248.
    • (1991) Nature , vol.349 , pp. 245-248
    • Kawabe, Y.1    Ochi, A.2
  • 29
    • 0033007321 scopus 로고    scopus 로고
    • Mature T lymphocyte apoptosis-immune regulation in a dynamic and unpredictable antigenic environment
    • Lenardo, M., et al. 1999. Mature T lymphocyte apoptosis-immune regulation in a dynamic and unpredictable antigenic environment. Annu. Rev. Immunol. 17:221-253.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 221-253
    • Lenardo, M.1
  • 30
    • 0038025292 scopus 로고    scopus 로고
    • Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo
    • Blattman, J.N., et al. 2003. Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo. Nat. Med. 9:540-547.
    • (2003) Nat. Med. , vol.9 , pp. 540-547
    • Blattman, J.N.1
  • 31
    • 18744373312 scopus 로고    scopus 로고
    • Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma
    • Romero, P., et al. 2002. Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma. Immunol. Rev. 188:81-96.
    • (2002) Immunol. Rev. , vol.188 , pp. 81-96
    • Romero, P.1
  • 32
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto, F., Lenig, D., Forster, R., Lipp, M., and Lanzavecchia, A. 1999. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature. 401:708-712.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 33
    • 0041941144 scopus 로고    scopus 로고
    • Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions
    • Rufer, N., et al. 2003. Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions. Blood. 102:1779-1787.
    • (2003) Blood , vol.102 , pp. 1779-1787
    • Rufer, N.1
  • 35
    • 0035340516 scopus 로고    scopus 로고
    • Kinetics of TCR use in response to repeated epitope-specific immunization
    • Monsurro, V., et al. 2001. Kinetics of TCR use in response to repeated epitope-specific immunization. J. Immunol. 166:5817-5825.
    • (2001) J. Immunol. , vol.166 , pp. 5817-5825
    • Monsurro, V.1
  • 36
    • 0029997742 scopus 로고    scopus 로고
    • Generation of cytotoxic T cell responses with synthetic melanoma associated peptides in vivo, implications for tumor vaccines with melanoma associated antigens
    • Jaeger, E., et al. 1996. Generation of cytotoxic T cell responses with synthetic melanoma associated peptides in vivo, implications for tumor vaccines with melanoma associated antigens. Int. J. Cancer. 66:162.
    • (1996) Int. J. Cancer , vol.66 , pp. 162
    • Jaeger, E.1
  • 37
    • 0742304314 scopus 로고    scopus 로고
    • Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor specific T cells
    • Speiser, D.E., et al. 2003. Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor specific T cells. Semin. Cancer Biol. 13:461-472.
    • (2003) Semin. Cancer Biol. , vol.13 , pp. 461-472
    • Speiser, D.E.1
  • 38
    • 0346024187 scopus 로고    scopus 로고
    • Phenotypic and functional maturation of tumor antigen-reactive CD8+ T lymphocytes in patients undergoing multiple course peptide vaccination
    • Powell, D.J., Jr., and Rosenberg, S.A. 2004. Phenotypic and functional maturation of tumor antigen-reactive CD8+ T lymphocytes in patients undergoing multiple course peptide vaccination. J. Immunother. 27:36-47.
    • (2004) J. Immunother. , vol.27 , pp. 36-47
    • Powell Jr., D.J.1    Rosenberg, S.A.2
  • 39
    • 0842343142 scopus 로고    scopus 로고
    • Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration
    • Heikenwalder, M., et al. 2004. Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration. Nat. Med. 10:187-192.
    • (2004) Nat. Med. , vol.10 , pp. 187-192
    • Heikenwalder, M.1
  • 40
    • 0344436049 scopus 로고    scopus 로고
    • Immunostimulacory CpG-oligodeoxynucleotides cause extramedullary murine hemopoiesis
    • Sparwasser, T., et al. 1999. Immunostimulacory CpG-oligodeoxynucleotides cause extramedullary murine hemopoiesis. J. Immunol. 162:2368-2374.
    • (1999) J. Immunol. , vol.162 , pp. 2368-2374
    • Sparwasser, T.1
  • 41
    • 1242276205 scopus 로고    scopus 로고
    • CpG-matured murine plasmacytoid dendritic cells are capable of in vivo priming of functional CD8 T cell responses to endogenous but not exogenous antigens
    • Salio, M., Palmowski, M.J., Atzberger, A., Hermans, I.F., and Cerundolo, V. 2004. CpG-matured murine plasmacytoid dendritic cells are capable of in vivo priming of functional CD8 T cell responses to endogenous but not exogenous antigens. J. Exp. Med. 199:567-579.
    • (2004) J. Exp. Med. , vol.199 , pp. 567-579
    • Salio, M.1    Palmowski, M.J.2    Atzberger, A.3    Hermans, I.F.4    Cerundolo, V.5
  • 42
    • 0032819985 scopus 로고    scopus 로고
    • High frequencies of naive Melan-A/MART-1-specific CD8+ T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals
    • Pittet, M.J., et al. 1999. High frequencies of naive Melan-A/MART-1- specific CD8+ T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals. J. Exp. Med. 190:705-715.
    • (1999) J. Exp. Med. , vol.190 , pp. 705-715
    • Pittet, M.J.1
  • 43
    • 10744227434 scopus 로고    scopus 로고
    • Priming of naive T cells inside tumors leads to eradication of established tumors
    • Yu, P., et al. 2004. Priming of naive T cells inside tumors leads to eradication of established tumors. Nat. Immunol. 5:141-149.
    • (2004) Nat. Immunol. , vol.5 , pp. 141-149
    • Yu, P.1
  • 44
    • 1142275273 scopus 로고    scopus 로고
    • LIGHTing the way for tumor immunity
    • Houghton, A.N. 2004. LIGHTing the way for tumor immunity. Nat. Immunol. 5:123-124.
    • (2004) Nat. Immunol. , vol.5 , pp. 123-124
    • Houghton, A.N.1
  • 45
    • 0035865054 scopus 로고    scopus 로고
    • Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs
    • Verthelyi, D., Ishii, K.J., Gursel, M., Takeshita, F., and Klinman, D.M. 2001. Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs. J. Immunol. 166:2372-2377.
    • (2001) J. Immunol. , vol.166 , pp. 2372-2377
    • Verthelyi, D.1    Ishii, K.J.2    Gursel, M.3    Takeshita, F.4    Klinman, D.M.5
  • 46
    • 0038236749 scopus 로고    scopus 로고
    • Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells
    • Hartmann, G., et al. 2003. Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells. Eur. J. Immunol. 33:1633-1641.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 1633-1641
    • Hartmann, G.1
  • 47
    • 0038341916 scopus 로고    scopus 로고
    • Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions
    • Marshall, J.D., et al. 2003. Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions. J. Leukoc. Biol. 73:781-792.
    • (2003) J. Leukoc. Biol. , vol.73 , pp. 781-792
    • Marshall, J.D.1
  • 48
    • 9144238063 scopus 로고    scopus 로고
    • Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities
    • Vollmer, J., et al. 2004. Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities. Eur. J. Immunol. 34:251-262.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 251-262
    • Vollmer, J.1
  • 49
    • 0034235706 scopus 로고    scopus 로고
    • IFN-alpha and IFN-beta: A link between immune memory and chronic inflammation
    • Akbar, A.N., Lord, J.M., and Salmon, M. 2000. IFN-alpha and IFN-beta: a link between immune memory and chronic inflammation. Immunol. Today. 21:337-342.
    • (2000) Immunol. Today , vol.21 , pp. 337-342
    • Akbar, A.N.1    Lord, J.M.2    Salmon, M.3
  • 51
    • 0029743737 scopus 로고    scopus 로고
    • Phenotypic analysis of antigen-specific T lymphocytes
    • Altman, J.D., et al. 1996. Phenotypic analysis of antigen-specific T lymphocytes. Science. 274:94-96.
    • (1996) Science , vol.274 , pp. 94-96
    • Altman, J.D.1


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