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Volumn 175, Issue 1, 2005, Pages 112-123

Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; DNA VACCINE; GAG PROTEIN; GAMMA INTERFERON; HEMAGGLUTININ; INTERLEUKIN 15; PLASMID VECTOR;

EID: 21244447927     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.1.112     Document Type: Article
Times cited : (162)

References (71)
  • 1
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • Sun, J. C., and M. J. Bevan. 2003. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300: 339-342.
    • (2003) Science , vol.300 , pp. 339-342
    • Sun, J.C.1    Bevan, M.J.2
  • 5
    • 1342345784 scopus 로고    scopus 로고
    • CD4 T cell-dependent CD8 T cell maturation
    • Khanolkar, A., M. J. Fuller, and A. J. Zajac. 2004. CD4 T cell-dependent CD8 T cell maturation. J. Immunol. 172: 2834-2844.
    • (2004) J. Immunol. , vol.172 , pp. 2834-2844
    • Khanolkar, A.1    Fuller, M.J.2    Zajac, A.J.3
  • 8
    • 0347382468 scopus 로고    scopus 로고
    • Mini-review CD4 T cells are required for CD8 T cell memory generation
    • Bourgeois, C., and C. Tanchot. 2003. Mini-review CD4 T cells are required for CD8 T cell memory generation. Eur. J. Immunol. 33: 3225-3231.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 3225-3231
    • Bourgeois, C.1    Tanchot, C.2
  • 9
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • Shedlock, D. J., and H. Shen. 2003. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 300: 337-339.
    • (2003) Science , vol.300 , pp. 337-339
    • Shedlock, D.J.1    Shen, H.2
  • 11
    • 0037442136 scopus 로고    scopus 로고
    • Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection
    • Shedlock, D. J., J. K. Whitmire, J. Tan, A. S. MacDonald, R. Ahmed, and H. Shen. 2003. Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection. J. Immunol. 170: 2053-2063.
    • (2003) J. Immunol. , vol.170 , pp. 2053-2063
    • Shedlock, D.J.1    Whitmire, J.K.2    Tan, J.3    MacDonald, A.S.4    Ahmed, R.5    Shen, H.6
  • 14
    • 0035824740 scopus 로고    scopus 로고
    • Helper-dependent vs. helper-independent CTL responses in HIV infection: Implications for drug therapy and resistance
    • Wodarz, D. 2001. Helper-dependent vs. helper-independent CTL responses in HIV infection: implications for drug therapy and resistance. J. Theor. Biol. 213: 447-459.
    • (2001) J. Theor. Biol. , vol.213 , pp. 447-459
    • Wodarz, D.1
  • 16
    • 0030846020 scopus 로고    scopus 로고
    • Cytotoxic T-lymphocyte cross-reactivity among different human immunodeficiency virus type 1 clades: Implications for vaccine development
    • Cao, H., P. Kanki, J. L. Sankale, A. Dieng-Sarr, G. P. Mazzara, S. A. Kalams, B. Korber, S. Mboup, and B. D. Walker. 1997. Cytotoxic T-lymphocyte cross-reactivity among different human immunodeficiency virus type 1 clades: implications for vaccine development. J. Virol. 71: 8615-8623.
    • (1997) J. Virol. , vol.71 , pp. 8615-8623
    • Cao, H.1    Kanki, P.2    Sankale, J.L.3    Dieng-Sarr, A.4    Mazzara, G.P.5    Kalams, S.A.6    Korber, B.7    Mboup, S.8    Walker, B.D.9
  • 17
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup, R. A., J. T. Safrit, Y. Cao, C. A. Andrews, G. McLeod, W. Borkowsky, C. Farthing, and D. D. Ho. 1994. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol 68: 4650-4655.
    • (1994) J. Virol. , vol.68 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3    Andrews, C.A.4    McLeod, G.5    Borkowsky, W.6    Farthing, C.7    Ho, D.D.8
  • 18
    • 0029116868 scopus 로고
    • High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors
    • Rinaldo, C., X. L. Huang, Z. F. Fan, M. Ding, L. Beltz, A. Logar, D. Panicali, G. Mazzara, J. Liebmann, M. Cottrill, et al. 1995. High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors. J. Virol. 69: 5838-5842.
    • (1995) J. Virol. , vol.69 , pp. 5838-5842
    • Rinaldo, C.1    Huang, X.L.2    Fan, Z.F.3    Ding, M.4    Beltz, L.5    Logar, A.6    Panicali, D.7    Mazzara, G.8    Liebmann, J.9    Cottrill, M.10
  • 20
    • 0027935476 scopus 로고
    • Antigen-independent activation of naive and memory resting T cells by a cytokine combination
    • Unutmaz, D., P. Pileri, and S. Abrignani. 1994. Antigen-independent activation of naive and memory resting T cells by a cytokine combination. J. Exp. Med. 180: 1159-1164.
    • (1994) J. Exp. Med. , vol.180 , pp. 1159-1164
    • Unutmaz, D.1    Pileri, P.2    Abrignani, S.3
  • 21
    • 0033977118 scopus 로고    scopus 로고
    • Stimulation of memory T cells by cytokines
    • Tough, D. F., S. Sun, X. Zhang, and J. Sprent. 2000. Stimulation of memory T cells by cytokines. Vaccine 18: 1642-1648.
    • (2000) Vaccine , vol.18 , pp. 1642-1648
    • Tough, D.F.1    Sun, S.2    Zhang, X.3    Sprent, J.4
  • 23
    • 16344392139 scopus 로고    scopus 로고
    • Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 +/- IL-15
    • McKee, H. I., Y. T'Sao, P., M. Vera, P. Fortes, and D. S. Strayer. 2004. Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 +/- IL-15. Genet. Vaccines Ther. 2: 10.
    • (2004) Genet. Vaccines Ther. , vol.2 , pp. 10
    • McKee, H.I.1    T'Sao, Y.2    Vera, P.M.3    Fortes, P.4    Strayer, D.S.5
  • 25
    • 0031852876 scopus 로고    scopus 로고
    • Interleukin-15 and its role in chronic inflammatory diseases
    • Kirman, I., B. Vainer, and O. H. Nielsen. 1998. Interleukin-15 and its role in chronic inflammatory diseases. Inflamm. Res. 47: 285-289.
    • (1998) Inflamm. Res. , vol.47 , pp. 285-289
    • Kirman, I.1    Vainer, B.2    Nielsen, O.H.3
  • 27
    • 3042548953 scopus 로고    scopus 로고
    • IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaques
    • Villinger, F., R. Miller, K. Mori, A. E. Mayne, P. Bostik, I. B. Sundstrom, C. Sugimoto, and A. A. Ansari. 2004. IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaques. Vaccine 22: 3510-3521.
    • (2004) Vaccine , vol.22 , pp. 3510-3521
    • Villinger, F.1    Miller, R.2    Mori, K.3    Mayne, A.E.4    Bostik, P.5    Sundstrom, I.B.6    Sugimoto, C.7    Ansari, A.A.8
  • 29
    • 0141446040 scopus 로고    scopus 로고
    • Interleukin-15 as an immune adjuvant to increase the efficacy of Mycobacterium bovis bacillus Calmette-Guerin vaccination
    • Umemura, M., H. Nishimura, K. Saito, T. Yajima, G. Matsuzaki, S. Mizuno, I. Sugawara, and Y. Yoshikai. 2003. Interleukin-15 as an immune adjuvant to increase the efficacy of Mycobacterium bovis bacillus Calmette-Guerin vaccination. Infect. Immun. 71: 6045-6048.
    • (2003) Infect. Immun. , vol.71 , pp. 6045-6048
    • Umemura, M.1    Nishimura, H.2    Saito, K.3    Yajima, T.4    Matsuzaki, G.5    Mizuno, S.6    Sugawara, I.7    Yoshikai, Y.8
  • 31
    • 0037452885 scopus 로고    scopus 로고
    • Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity
    • Oh, S., I. A. Berzofsky, D. S. Burke, T. A. Waldmann, and L. P. Perera. 2003. Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity. Proc. Natl. Acad. Sci. USA 100: 3392-3397.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 3392-3397
    • Oh, S.1    Berzofsky, I.A.2    Burke, D.S.3    Waldmann, T.A.4    Perera, L.P.5
  • 33
    • 0035850966 scopus 로고    scopus 로고
    • Adjuvant effects of IL-1β, IL-2, IL-8, IL-15, IFN-α, IFN-γ TGF-β4 and lymphotactin on DNA vaccination against Eimeria acervulina
    • Min, W., H. S. Lillehoj, I. Burnside, K. C. Weining, P. Staeheli, and J. J. Zhu. 2001. Adjuvant effects of IL-1β, IL-2, IL-8, IL-15, IFN-α, IFN-γ TGF-β4 and lymphotactin on DNA vaccination against Eimeria acervulina. Vaccine 20: 267-274.
    • (2001) Vaccine , vol.20 , pp. 267-274
    • Min, W.1    Lillehoj, H.S.2    Burnside, I.3    Weining, K.C.4    Staeheli, P.5    Zhu, J.J.6
  • 34
    • 0035898921 scopus 로고    scopus 로고
    • The immune response to a DNA vaccine can be modulated by co-delivery of cytokine genes using a DNA prime-protein boost strategy
    • Scheerlinck, J. P., G. Casey, P. McWaters, J. Kelly, D. Woollard, M. W. Lightowlers, J. M. Tennent, and P. J. Chaplin. 2001. The immune response to a DNA vaccine can be modulated by co-delivery of cytokine genes using a DNA prime-protein boost strategy. Vaccine 19: 4053-4060.
    • (2001) Vaccine , vol.19 , pp. 4053-4060
    • Scheerlinck, J.P.1    Casey, G.2    McWaters, P.3    Kelly, J.4    Woollard, D.5    Lightowlers, M.W.6    Tennent, J.M.7    Chaplin, P.J.8
  • 35
    • 0033899375 scopus 로고    scopus 로고
    • Gene transfer of a secretable form of IL-15 in murine adenocarcinoma cells: Effects on tumorigenicity, metastatic potential and immune response
    • Meazza, R., P. L. Lollini, P. Nanni, C. De Giovanni, A. Gaggero, A. Comes, M. Cilli, E. Di Carlo, S. Ferrini, and P. Musiani. 2000. Gene transfer of a secretable form of IL-15 in murine adenocarcinoma cells: effects on tumorigenicity, metastatic potential and immune response. Int. J. Cancer 87: 574-581.
    • (2000) Int. J. Cancer , vol.87 , pp. 574-581
    • Meazza, R.1    Lollini, P.L.2    Nanni, P.3    De Giovanni, C.4    Gaggero, A.5    Comes, A.6    Cilli, M.7    Di Carlo, E.8    Ferrini, S.9    Musiani, P.10
  • 36
    • 0033605274 scopus 로고    scopus 로고
    • IL-15 expression plasmid enhances cell-mediated immunity induced by an HIV-1 DNA vaccine
    • Xin, K. Q., K. Hamajima, S. Sasaki, T. Tsuji, S. Watabe, E. Okada, and K. Okuda. 1999. IL-15 expression plasmid enhances cell-mediated immunity induced by an HIV-1 DNA vaccine. Vaccine 17: 858-866.
    • (1999) Vaccine , vol.17 , pp. 858-866
    • Xin, K.Q.1    Hamajima, K.2    Sasaki, S.3    Tsuji, T.4    Watabe, S.5    Okada, E.6    Okuda, K.7
  • 37
    • 3042817388 scopus 로고    scopus 로고
    • Enhanced efficacy of DNA vaccination against Her-2/neu tumor antigen by genetic adjuvants
    • Chang, S. Y., K. C. Lee, S. Y. Ko, H. J. Ko, and C. Y. Kang. 2004. Enhanced efficacy of DNA vaccination against Her-2/neu tumor antigen by genetic adjuvants. Int. J. Cancer 111: 86-95.
    • (2004) Int. J. Cancer , vol.111 , pp. 86-95
    • Chang, S.Y.1    Lee, K.C.2    Ko, S.Y.3    Ko, H.J.4    Kang, C.Y.5
  • 40
    • 0038803926 scopus 로고    scopus 로고
    • + memory T cells generated in vitro from Listeria-immunized mice
    • + memory T cells generated in vitro from Listeria-immunized mice. Immunology 109: 450-460.
    • (2003) Immunology , vol.109 , pp. 450-460
    • Rayevskaya, M.1    Kushnir, N.2    Frankel, F.R.3
  • 41
    • 0037093844 scopus 로고    scopus 로고
    • Cutting edge: Requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells
    • Schluns, K. S., K. Williams, A. Ma, X. X. Zheng, and L. Lefrancois. 2002. Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells. J. Immunol. 168: 4827-4831.
    • (2002) J. Immunol. , vol.168 , pp. 4827-4831
    • Schluns, K.S.1    Williams, K.2    Ma, A.3    Zheng, X.X.4    Lefrancois, L.5
  • 42
    • 0029946063 scopus 로고    scopus 로고
    • IL-15: A pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels
    • Tagaya, Y., R. N. Bamford, A. P. DeFilippis, and T. A. Waldmann. 1996. IL-15: a pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels. Immunity 4: 329-336.
    • (1996) Immunity , vol.4 , pp. 329-336
    • Tagaya, Y.1    Bamford, R.N.2    DeFilippis, A.P.3    Waldmann, T.A.4
  • 43
    • 0033046593 scopus 로고    scopus 로고
    • The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens
    • Waldmann, T. A., and Y. Tagaya. 1999. The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens. Annu. Rev. Immunol. 17: 19-49.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 19-49
    • Waldmann, T.A.1    Tagaya, Y.2
  • 45
    • 0030639208 scopus 로고    scopus 로고
    • Regulation of IL-15 secretion via the leader peptide of two IL-15 isoforms
    • Onu, A., T. Pohl, H. Krause, and S. Bulfone-Paus. 1997. Regulation of IL-15 secretion via the leader peptide of two IL-15 isoforms. J. Immunol. 158: 255-262.
    • (1997) J. Immunol. , vol.158 , pp. 255-262
    • Onu, A.1    Pohl, T.2    Krause, H.3    Bulfone-Paus, S.4
  • 46
    • 0032080666 scopus 로고    scopus 로고
    • The 5′ untranslated region, signal peptide, and the coding sequence of the carboxyl terminus of IL-15 participate in its multifaceted translational control
    • Bamford, R. N., A. P. DeFilippis, N. Azimi, G. Kurys, and T. A. Waldmann. 1998. The 5′ untranslated region, signal peptide, and the coding sequence of the carboxyl terminus of IL-15 participate in its multifaceted translational control. J. Immunol. 160: 4418-4426.
    • (1998) J. Immunol. , vol.160 , pp. 4418-4426
    • Bamford, R.N.1    DeFilippis, A.P.2    Azimi, N.3    Kurys, G.4    Waldmann, T.A.5
  • 48
    • 0037033070 scopus 로고    scopus 로고
    • Carboxyl terminus of hVIP/mov34 is critical for HIV-1-Vpr interaction and glucocorticoid-mediated signaling
    • Ramanathan, M. P., E. Curley III, M. Su, J. A. Chambers, and D. B. Weiner. 2002. Carboxyl terminus of hVIP/mov34 is critical for HIV-1-Vpr interaction and glucocorticoid-mediated signaling. J. Biol. Chem. 277: 47854-47860.
    • (2002) J. Biol. Chem. , vol.277 , pp. 47854-47860
    • Ramanathan, M.P.1    Curley III, E.2    Su, M.3    Chambers, J.A.4    Weiner, D.B.5
  • 50
    • 0030750733 scopus 로고    scopus 로고
    • DNA immunization for influenza virus: Studies using hemagglutinin- and nucleoprotein-expressing DNAs
    • Robinson, H. L., C. A. Boyle, D. M. Feltquate, M. J. Morin, J. C. Santoro, and R. G. Webster. 1997. DNA immunization for influenza virus: studies using hemagglutinin- and nucleoprotein-expressing DNAs. J. Infect. Dis. 176(Suppl. 1): S50-S55.
    • (1997) J. Infect. Dis. , vol.176 , Issue.SUPPL. 1
    • Robinson, H.L.1    Boyle, C.A.2    Feltquate, D.M.3    Morin, M.J.4    Santoro, J.C.5    Webster, R.G.6
  • 51
    • 1842584373 scopus 로고    scopus 로고
    • Co-immunization with plasmid IL-12 generates a strong T-cell memory response in mice
    • Chattergoon, M. A., V. Saulino, J. P. Shames, J. Stein, L. J. Montaner, and D. B. Weiner. 2004. Co-immunization with plasmid IL-12 generates a strong T-cell memory response in mice. Vaccine 22: 1744-1750.
    • (2004) Vaccine , vol.22 , pp. 1744-1750
    • Chattergoon, M.A.1    Saulino, V.2    Shames, J.P.3    Stein, J.4    Montaner, L.J.5    Weiner, D.B.6
  • 53
    • 0030047144 scopus 로고    scopus 로고
    • Identification of a novel interleukin-15 (IL-15) transcript isoform generated by alternative splicing in human small cell lung cancer cell lines
    • Meazza, R., S. Verdiani, R. Biassoni, M. Coppolecchia, A. Gaggero, A. M. Orengo, M. P. Colombo, B. Azzarone, and S. Ferrini. 1996. Identification of a novel interleukin-15 (IL-15) transcript isoform generated by alternative splicing in human small cell lung cancer cell lines. Oncogene 12: 2187-2192.
    • (1996) Oncogene , vol.12 , pp. 2187-2192
    • Meazza, R.1    Verdiani, S.2    Biassoni, R.3    Coppolecchia, M.4    Gaggero, A.5    Orengo, A.M.6    Colombo, M.P.7    Azzarone, B.8    Ferrini, S.9
  • 55
    • 0032530748 scopus 로고    scopus 로고
    • The MHC class I-restricted immune response to HIV-gag in BALB/c mice selects a single epitope that does not have a predictable MHC-binding motif and binds to Kd through interactions between a glutamine at P3 and pocket D
    • Mata, M., P. J. Travers, Q. Liu, F. R. Frankel, and Y. Paterson. 1998. The MHC class I-restricted immune response to HIV-gag in BALB/c mice selects a single epitope that does not have a predictable MHC-binding motif and binds to Kd through interactions between a glutamine at P3 and pocket D. J. Immunol. 161: 2985-2993.
    • (1998) J. Immunol. , vol.161 , pp. 2985-2993
    • Mata, M.1    Travers, P.J.2    Liu, Q.3    Frankel, F.R.4    Paterson, Y.5
  • 57
    • 0028820386 scopus 로고
    • Reconstitution of cellular immunity against cytomegalovinis in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor
    • Walter, E. A., P. D. Greenberg, M. J. Gilbert, R. J. Finch, K. S. Watanabe, E. D. Thomas, and S. R. Riddell. 1995. Reconstitution of cellular immunity against cytomegalovinis in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. N. Engl. J. Med. 333: 1038-1044.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 1038-1044
    • Walter, E.A.1    Greenberg, P.D.2    Gilbert, M.J.3    Finch, R.J.4    Watanabe, K.S.5    Thomas, E.D.6    Riddell, S.R.7
  • 59
    • 0035202257 scopus 로고    scopus 로고
    • Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response
    • Ohteki, T., K. Suzue, C. Maki, T. Ota, and S. Koyasu. 2001. Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response. Nat. Immunol. 1: 1138-1143.
    • (2001) Nat. Immunol. , vol.1 , pp. 1138-1143
    • Ohteki, T.1    Suzue, K.2    Maki, C.3    Ota, T.4    Koyasu, S.5
  • 62
    • 0032211699 scopus 로고    scopus 로고
    • IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
    • Lodolce, J. P., D. L. Boone, S. Chai, R. E. Swain, T. Dassopoulos, S. Trettin, and A. Ma. 1998. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 9: 669-676.
    • (1998) Immunity , vol.9 , pp. 669-676
    • Lodolce, J.P.1    Boone, D.L.2    Chai, S.3    Swain, R.E.4    Dassopoulos, T.5    Trettin, S.6    Ma, A.7
  • 63
    • 0142156243 scopus 로고    scopus 로고
    • New strategies to control inflammatory synovitis: Interleukin 15 and beyond
    • McInnes, I. B., J. A. Gracie, M. Haraett, W. Harnett, and F. Y. Liew. 2003. New strategies to control inflammatory synovitis: interleukin 15 and beyond. Ann. Rheum. Dis. 62(Suppl. 2): ii51-ii54.
    • (2003) Ann. Rheum. Dis. , vol.62 , Issue.SUPPL. 2
    • McInnes, I.B.1    Gracie, J.A.2    Haraett, M.3    Harnett, W.4    Liew, F.Y.5
  • 65
    • 34247638873 scopus 로고    scopus 로고
    • The contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: Implications for the immunotherapy of rheumatological diseases
    • Waldmann, T. 2002. The contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseases. Arthritis Res. 4(Suppl. 3): S161-S167.
    • (2002) Arthritis Res. , vol.4 , Issue.SUPPL. 3
    • Waldmann, T.1
  • 66
    • 0037090076 scopus 로고    scopus 로고
    • A role for IL-15 in driving the onset of spontaneous autoimmune thyroiditis?
    • Kaiser, P., L. Rothwell, D. Vasicek, and K. Hala. 2002. A role for IL-15 in driving the onset of spontaneous autoimmune thyroiditis? J. Immunol. 168: 4216-4220.
    • (2002) J. Immunol. , vol.168 , pp. 4216-4220
    • Kaiser, P.1    Rothwell, L.2    Vasicek, D.3    Hala, K.4
  • 67
    • 0242492516 scopus 로고    scopus 로고
    • Lack of the mediators of innate immunity attenuate the development of autoimmune diabetes in mice
    • Lukic, M. L., E. Mensah-Brown, X. Wei, A. Shahin, and F. Y. Liew. 2003. Lack of the mediators of innate immunity attenuate the development of autoimmune diabetes in mice. J. Autoimmun. 21: 239-246.
    • (2003) J. Autoimmun. , vol.21 , pp. 239-246
    • Lukic, M.L.1    Mensah-Brown, E.2    Wei, X.3    Shahin, A.4    Liew, F.Y.5
  • 68
    • 0033496599 scopus 로고    scopus 로고
    • Production of interleukin-7 and interleukin-15 by fibroblast-like synoviocytes from patients with rheumatoid arthritis
    • Harada, S., M. Yamamura, H. Okamoto, Y. Morita, M. Kawashima, T. Aita, and H. Makino. 1999. Production of interleukin-7 and interleukin-15 by fibroblast-like synoviocytes from patients with rheumatoid arthritis. Arthritis Rheum. 42: 1508-1516.
    • (1999) Arthritis Rheum. , vol.42 , pp. 1508-1516
    • Harada, S.1    Yamamura, M.2    Okamoto, H.3    Morita, Y.4    Kawashima, M.5    Aita, T.6    Makino, H.7
  • 69
    • 0036170643 scopus 로고    scopus 로고
    • Immunoregulation during disease progression in prediabetic NOD mice: Inverse expression of arginase and prostaglandin H synthase 2 vs. interleukin-15
    • Rothe, H., A. Hausmann, and H. Kolb. 2002. Immunoregulation during disease progression in prediabetic NOD mice: inverse expression of arginase and prostaglandin H synthase 2 vs. interleukin-15. Horm. Metab. Res. 34: 7-12.
    • (2002) Horm. Metab. Res. , vol.34 , pp. 7-12
    • Rothe, H.1    Hausmann, A.2    Kolb, H.3
  • 70
    • 0037003871 scopus 로고    scopus 로고
    • IL-15 is elevated in sera of patients with relapsing-remitting multiple sclerosis
    • Losy, J., A. Niezgoda, and J. Zaremba. 2002. IL-15 is elevated in sera of patients with relapsing-remitting multiple sclerosis. Folia Neuropathol. 40: 151-153.
    • (2002) Folia Neuropathol. , vol.40 , pp. 151-153
    • Losy, J.1    Niezgoda, A.2    Zaremba, J.3
  • 71
    • 0032103993 scopus 로고    scopus 로고
    • Soluble IL-15 receptor α-chain administration prevents murine collagen-induced arthritis: A role for IL-15 in development of antigen-induced immunopathology
    • Ruchatz, H., B. P. Leung, X. Q. Wei, I. B. McInnes, and F. Y. Liew. 1998. Soluble IL-15 receptor α-chain administration prevents murine collagen-induced arthritis: a role for IL-15 in development of antigen-induced immunopathology. J. Immunol. 160: 5654-5660.
    • (1998) J. Immunol. , vol.160 , pp. 5654-5660
    • Ruchatz, H.1    Leung, B.P.2    Wei, X.Q.3    McInnes, I.B.4    Liew, F.Y.5


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