메뉴 건너뛰기




Volumn 29, Issue 3, 2006, Pages 313-319

IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells

Author keywords

Human lymphocytes; Interleukin 7; Lymphopoiesis; Regulatory T cells

Indexed keywords

INTERLEUKIN 7; NEUTRALIZING ANTIBODY; RECOMBINANT INTERLEUKIN 7; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN;

EID: 33746046073     PISSN: 15249557     EISSN: None     Source Type: Journal    
DOI: 10.1080/03601270600564088     Document Type: Article
Times cited : (375)

References (22)
  • 1
    • 0036624721 scopus 로고    scopus 로고
    • Interleukin-7: From bench to clinic
    • Fry TJ, Mackall CL. Interleukin-7: from bench to clinic. Blood. 2002;99:3892-3904.
    • (2002) Blood , vol.99 , pp. 3892-3904
    • Fry, T.J.1    Mackall, C.L.2
  • 2
    • 0035874499 scopus 로고    scopus 로고
    • A potential role for interleukin-7 in T-cell homeostasis
    • Fry TJ, Connick E, Falloon J, et al. A potential role for interleukin-7 in T-cell homeostasis. Blood. 2001;97:2983-2990.
    • (2001) Blood , vol.97 , pp. 2983-2990
    • Fry, T.J.1    Connick, E.2    Falloon, J.3
  • 3
    • 0027988545 scopus 로고
    • Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
    • Peschon JJ, Morrissey PJ, Grabstein KH, et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med. 1994;180:1955-1960.
    • (1994) J Exp Med , vol.180 , pp. 1955-1960
    • Peschon, J.J.1    Morrissey, P.J.2    Grabstein, K.H.3
  • 4
    • 0025981025 scopus 로고
    • Administration of IL-7 to mice with cyclophosphamide-induced lymphopenia accelerates lymphocyte repopulation
    • Morrissey PJ, Conlon P, Braddy S, et al. Administration of IL-7 to mice with cyclophosphamide-induced lymphopenia accelerates lymphocyte repopulation. J Immunol. 1991;146:1547-1552.
    • (1991) J Immunol , vol.146 , pp. 1547-1552
    • Morrissey, P.J.1    Conlon, P.2    Braddy, S.3
  • 5
    • 0027496019 scopus 로고
    • T-cell reconstitution by molecular, phenotypic, and functional analysis in the thymus, bone marrow, spleen, and blood following split-dose polychemotherapy and therapeutic activity for metastatic breast cancer in mice
    • Talmadge JE, Jackson JD, Kelsey L, et al. T-cell reconstitution by molecular, phenotypic, and functional analysis in the thymus, bone marrow, spleen, and blood following split-dose polychemotherapy and therapeutic activity for metastatic breast cancer in mice. J Immunother. 1993;14:258-268.
    • (1993) J Immunother , vol.14 , pp. 258-268
    • Talmadge, J.E.1    Jackson, J.D.2    Kelsey, L.3
  • 6
    • 4444284575 scopus 로고    scopus 로고
    • A dose effect of IL-7 on thymocyte development
    • El Kassar N, Lucas PJ, Klug D, et al. A dose effect of IL-7 on thymocyte development. Blood. 2004;104:1419-1427.
    • (2004) Blood , vol.104 , pp. 1419-1427
    • El Kassar, N.1    Lucas, P.J.2    Klug, D.3
  • 7
    • 3843124199 scopus 로고    scopus 로고
    • TCR Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhancing thymic function
    • Chu Y, Memon S, Sharrow S, et al. TCR Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhancing thymic function. Blood. 2004;104:1110-1119.
    • (2004) Blood , vol.104 , pp. 1110-1119
    • Chu, Y.1    Memon, S.2    Sharrow, S.3
  • 8
    • 0028924203 scopus 로고
    • Lymphoproliferative disorders in IL-7 transgenic mice: Expansion of immature B cells which retain macrophage potential
    • Fisher AG, Burdet C, Bunce C, et al. Lymphoproliferative disorders in IL-7 transgenic mice: expansion of immature B cells which retain macrophage potential. Int Immunol. 1995;7:415-423.
    • (1995) Int Immunol , vol.7 , pp. 415-423
    • Fisher, A.G.1    Burdet, C.2    Bunce, C.3
  • 9
    • 0026027238 scopus 로고
    • Development of lymphocytes in interleukin 7-transgenic mice
    • Samaridis J, Casorati G, Traunecker A, et al. Development of lymphocytes in interleukin 7-transgenic mice. Eur J Immunol. 1991;21:453-460.
    • (1991) Eur J Immunol , vol.21 , pp. 453-460
    • Samaridis, J.1    Casorati, G.2    Traunecker, A.3
  • 10
    • 0030199773 scopus 로고    scopus 로고
    • Development of CD4 and CD8 single positive T cells in human thymus organ culture: IL-7 promotes human T cell production by supporting immature T cells
    • Yeoman H, Clark DR, DeLuca D. Development of CD4 and CD8 single positive T cells in human thymus organ culture: IL-7 promotes human T cell production by supporting immature T cells. Dev Comp Immunol. 1996;20:241-263.
    • (1996) Dev Comp Immunol , vol.20 , pp. 241-263
    • Yeoman, H.1    Clark, D.R.2    DeLuca, D.3
  • 11
    • 0031740732 scopus 로고    scopus 로고
    • Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency
    • Puel A, Ziegler SF, Buckley RH, et al. Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency. Nat Genet. 1998;20:394-397.
    • (1998) Nat Genet , vol.20 , pp. 394-397
    • Puel, A.1    Ziegler, S.F.2    Buckley, R.H.3
  • 12
    • 0037443464 scopus 로고    scopus 로고
    • IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates
    • Fry TJ, Moniuszko M, Creekmore S, et al. IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates. Blood. 2003;101:2294-2299.
    • (2003) Blood , vol.101 , pp. 2294-2299
    • Fry, T.J.1    Moniuszko, M.2    Creekmore, S.3
  • 13
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S. Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol. 2004;22:531-562.
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 14
    • 20044363610 scopus 로고    scopus 로고
    • CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells
    • Antony PA, Piccirillo CA, Akpinarli A, et al. CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells. J Immunol. 2005;174:2591-2601.
    • (2005) J Immunol , vol.174 , pp. 2591-2601
    • Antony, P.A.1    Piccirillo, C.A.2    Akpinarli, A.3
  • 15
    • 3543045638 scopus 로고    scopus 로고
    • Prospective immunological profiling in a case of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX)
    • Bakke AC, Purtzer MZ, Wildin RS. Prospective immunological profiling in a case of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX). Clin Exp Immunol. 2004;137:373-378.
    • (2004) Clin Exp Immunol , vol.137 , pp. 373-378
    • Bakke, A.C.1    Purtzer, M.Z.2    Wildin, R.S.3
  • 16
    • 0348047537 scopus 로고    scopus 로고
    • The main function of IL-2 is to promote the development of T regulatory cells
    • Malek TR. The main function of IL-2 is to promote the development of T regulatory cells. J Leukoc Biol. 2003;74:961-965.
    • (2003) J Leukoc Biol , vol.74 , pp. 961-965
    • Malek, T.R.1
  • 17
    • 33644784733 scopus 로고    scopus 로고
    • IL-2 administration increases CD4+CD25hiFoxp3+ regulatory T cells in cancer patients
    • Ahmadzadeh M, Rosenberg SA. IL-2 administration increases CD4+CD25hiFoxp3+ regulatory T cells in cancer patients. Blood. 2006;107:2409-2414.
    • (2006) Blood , vol.107 , pp. 2409-2414
    • Ahmadzadeh, M.1    Rosenberg, S.A.2
  • 19
    • 0028912032 scopus 로고
    • Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection
    • Kovacs JA, Baseler M, Dewar RJ, et al. Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. N Engl J Med. 1995;332:567-575.
    • (1995) N Engl J Med , vol.332 , pp. 567-575
    • Kovacs, J.A.1    Baseler, M.2    Dewar, R.J.3
  • 20
    • 22144470799 scopus 로고    scopus 로고
    • + T cells expressing foxP3 in IL-2-treated HIV-infected patients
    • + T cells expressing foxP3 in IL-2-treated HIV-infected patients. J Clin Invest. 2005;115:1839-1847.
    • (2005) J Clin Invest , vol.115 , pp. 1839-1847
    • Sereti, I.1    Imamichi, H.2    Natarajan, V.3
  • 21
    • 0031890206 scopus 로고    scopus 로고
    • Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
    • Rosenberg SA, Yang JC, Schwartzentruber DJ, et al. Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nat Med. 1998;4:321-327.
    • (1998) Nat Med , vol.4 , pp. 321-327
    • Rosenberg, S.A.1    Yang, J.C.2    Schwartzentruber, D.J.3
  • 22
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: moving beyond current vaccines. Nat Med. 2004;10:909-915.
    • (2004) Nat Med , vol.10 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.