Molecular targeting of Gα and Gβγ subunits: A potential approach for cancer therapeutics

Trends in Pharmacological Sciences

Volumn 34, Issue 5, 2013, Pages 290-298

  Smrcka, Alan V ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; BIM 46174; BIM 46187; G PROTEIN COUPLED RECEPTOR; GALLEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA GAMMA SUBUNIT; IMIDAZOPYRAZINE DERIVATIVE; M 119; RGS PROTEIN; SURAMIN; UNCLASSIFIED DRUG; YM 254890;

BINDING AFFINITY; BINDING SITE; CANCER INHIBITION; DISEASE ASSOCIATION; DISEASE MARKER; DRUG EFFECT; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG RESPONSE; DRUG STRUCTURE; DRUG TARGETING; HUMAN; IC 50; MALIGNANT NEOPLASTIC DISEASE; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; GTP-BINDING PROTEIN ALPHA SUBUNITS; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; HUMANS; MOLECULAR TARGETED THERAPY; NEOPLASMS;

EID: 84876898526     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2013.02.006     Document Type: Review

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