Addicting drugs utilize a synergistic molecular mechanism in common requiring adenosine and Gi-βγ dimers

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue SUPPL. 2, 2003, Pages 14379-14384

  Yao, Lina ^a,b   Fan, Peidong ^a   Jiang, Zhan ^a   Mailliard, William S ^a,b   Gordon, Adrienne S ^a,b,c   Diamond, Ivan ^a,b,c  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADENOSINE A2 RECEPTOR; ALCOHOL; CANNABINOID; CANNABINOID 1 RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIMER; DOPAMINE 2 RECEPTOR; GAMMA OPIATE RECEPTOR; GI BETA GAMMA DIMER; OPIATE; OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL STRAIN; CELL STRAIN NG 108 15; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOPAMINERGIC SYSTEM; DRUG DEPENDENCE; DRUG HYPERSENSITIVITY; GENE EXPRESSION; MOLECULAR BIOLOGY; MOUSE; NERVE CELL; NEUROBIOLOGY; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL;

ADENOSINE; ANIMALS; ARACHIDONIC ACIDS; CELL LINE; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DIMERIZATION; DOPAMINE AGONISTS; DRUG SYNERGISM; ENKEPHALIN, LEUCINE-2-ALANINE; ETHANOL; GTP-BINDING PROTEIN BETA SUBUNITS; ISOENZYMES; MODELS, NEUROLOGICAL; NEURONS; RATS; RECEPTOR, CANNABINOID, CB1; RECEPTORS, ADENOSINE A2; RECEPTORS, OPIOID, DELTA; SUBSTANCE-RELATED DISORDERS;

ANIMALIA;

EID: 0345492359     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2336093100     Document Type: Article

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