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Despite extensive screening of a variety of easily available chiral Brønsted bases for the reaction of nitroacetate 1 a and preformed imine 9 under the indicated reaction conditions, 4 a was obtained in only 3 % ee.
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Despite extensive screening of a variety of easily available chiral Brønsted bases for the reaction of nitroacetate 1 a and preformed imine 9 under the indicated reaction conditions, 4 a was obtained in only 3 % ee.
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