PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis

Oncogene

Volumn 32, Issue 14, 2013, Pages 1761-1771

  Rybanska, I ^a,b   Ishaq, O ^a,b   Chou, J ^a,b   Prakash, M ^a,b   Bakhsheshian, J ^a,b   Huso, D L ^b   Franco, S ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

DNA PKcs; lymphoma; mutation; p53; PARP1; telomere

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; DNA DEPENDENT PROTEIN KINASE; DNA DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN P53; UNCLASSIFIED DRUG;

ANEUPLOIDY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EXON; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENOMIC INSTABILITY; IN VIVO STUDY; INDEL MUTATION; KARYOTYPING; LYMPHOMA; METAPHASE; MISSENSE MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; RADIOSENSITIVITY; TELOMERE; THYMOCYTE; TUMOR CELL; VDJ RECOMBINATION;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CESIUM RADIOISOTOPES; CHROMOSOME ABERRATIONS; DNA; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; FEMALE; GENOMIC INSTABILITY; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION, FLUORESCENCE; LYMPHOMA; MALE; MICE; MICE, KNOCKOUT; MUTATION; NUCLEAR PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; RADIATION TOLERANCE; REAL-TIME POLYMERASE CHAIN REACTION; TELOMERE; THYMOCYTES; TRANSLOCATION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

MUS;

EID: 84876119428     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.199     Document Type: Article

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