Shorter telomeres, accelerated ageing and increased lymphoma in DNA-PKcs-deficient mice

EMBO Reports

Volumn 5, Issue 5, 2004, Pages 503-509

  Espejel, Silvia ^a   Martín, Marta ^b   Klatt, Peter ^a   Martín Caballero, Juan ^a   Flores, Juana M ^c   Blasco, María A ^a  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Ageing; Cancer; DNA repair; DNA PKcs; Telomeres

Indexed keywords

DNA DEPENDENT PROTEIN KINASE; PROTEIN SUBUNIT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME DEFICIENCY; FOLLOW UP; INCIDENCE; INFECTION RISK; LIFESPAN; MALE; MOUSE; NONHUMAN; PREMATURE AGING; PRIORITY JOURNAL; T CELL LYMPHOMA; TELOMERE; WILD TYPE;

AGING; ANIMALS; BODY WEIGHT; CELL CYCLE; CHROMOSOMES; DNA DAMAGE; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; FEMALE; LIFE EXPECTANCY; LYMPHOMA; MALE; MEIOSIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; SPINE; TELOMERE; TESTIS;

MAMMALIA;

EID: 2942547771     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.7400127     Document Type: Article

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