-
1
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-739.
-
(2006)
Cell
, vol.126
, pp. 663-739
-
-
Takahashi, K.1
Yamanaka, S.2
-
2
-
-
79953881831
-
Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency
-
Anokye-Danso F, et al. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell 2011;8:376-388.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 376-388
-
-
Anokye-Danso, F.1
-
3
-
-
79957855262
-
Reprogramming of mouse and human cells to pluripotency using mature microRNAs
-
Miyoshi N, et al. Reprogramming of mouse and human cells to pluripotency using mature microRNAs. Cell Stem Cell 2011;8:633-638.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 633-638
-
-
Miyoshi, N.1
-
4
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
Lim LP, et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005;433:769-773.
-
(2005)
Nature
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
-
5
-
-
80051684096
-
MicroRNA-mediated conversion of human fibroblasts to neurons
-
Yoo AS, et al. MicroRNA-mediated conversion of human fibroblasts to neurons. Nature 2011;476:228-231.
-
(2011)
Nature
, vol.476
, pp. 228-231
-
-
Yoo, A.S.1
-
6
-
-
34250735674
-
RNA regulons: coordination of post-transcriptional events
-
Keene J. RNA regulons: coordination of post-transcriptional events. Nat Rev Genet 2007;8:533-543.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 533-543
-
-
Keene, J.1
-
7
-
-
84862776981
-
Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis
-
Yuan J, Nguyen CK, Liu X, Kanellopoulou C, Muljo SA. Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis. Science 2012;335:1195-1200.
-
(2012)
Science
, vol.335
, pp. 1195-1200
-
-
Yuan, J.1
Nguyen, C.K.2
Liu, X.3
Kanellopoulou, C.4
Muljo, S.A.5
-
8
-
-
0021771445
-
Heterochronic mutants of the nematode Caenorhabditis elegans
-
Ambros V, Horvitz HR. Heterochronic mutants of the nematode Caenorhabditis elegans. Science 1984;226:409-416.
-
(1984)
Science
, vol.226
, pp. 409-416
-
-
Ambros, V.1
Horvitz, H.R.2
-
9
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993;75:843-854.
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
10
-
-
0027730383
-
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
-
Wightman B, Ha I, Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 1993;75:855-862.
-
(1993)
Cell
, vol.75
, pp. 855-862
-
-
Wightman, B.1
Ha, I.2
Ruvkun, G.3
-
11
-
-
0030970775
-
The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA
-
Moss EG, Lee RC, Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell 1997;88:637-646.
-
(1997)
Cell
, vol.88
, pp. 637-646
-
-
Moss, E.G.1
Lee, R.C.2
Ambros, V.3
-
12
-
-
0034708122
-
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
-
Reinhart B, et al. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 2000;403:901-907.
-
(2000)
Nature
, vol.403
, pp. 901-907
-
-
Reinhart, B.1
-
13
-
-
0034597777
-
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
-
Pasquinelli AE, et al. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 2000;408:86-89.
-
(2000)
Nature
, vol.408
, pp. 86-89
-
-
Pasquinelli, A.E.1
-
14
-
-
79960924567
-
MicroRNAs and developmental timing
-
Ambros V. MicroRNAs and developmental timing. Curr Opin Genet Dev 2011;21:511-517.
-
(2011)
Curr Opin Genet Dev
, vol.21
, pp. 511-517
-
-
Ambros, V.1
-
15
-
-
77955902024
-
The widespread regulation of microRNA biogenesis, function and decay
-
Krol J, Loedige I, Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 2010;11:597-610.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 597-610
-
-
Krol, J.1
Loedige, I.2
Filipowicz, W.3
-
16
-
-
0037197803
-
Identification of tissue-specific microRNAs from mouse
-
Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T. Identification of tissue-specific microRNAs from mouse. Curr Biol 2002;12:735-739.
-
(2002)
Curr Biol
, vol.12
, pp. 735-739
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Yalcin, A.3
Meyer, J.4
Lendeckel, W.5
Tuschl, T.6
-
17
-
-
33644750115
-
miRBase: microRNA sequences, targets and gene nomenclature
-
Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res 2006;34:D140-D144.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Griffiths-Jones, S.1
Grocock, R.J.2
van Dongen, S.3
Bateman, A.4
Enright, A.J.5
-
18
-
-
0346094457
-
Prediction of mammalian microRNA targets
-
Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell 2003;115:787-798.
-
(2003)
Cell
, vol.115
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
Bartel, D.P.4
Burge, C.B.5
-
19
-
-
15244358503
-
Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals
-
Xie X, et al. Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals. Nature 2005;434:338-345.
-
(2005)
Nature
, vol.434
, pp. 338-345
-
-
Xie, X.1
-
20
-
-
34250682267
-
Deep conservation of microRNA-target relationships and 3′UTR motifs in vertebrates, flies, and nematodes
-
Chen K, Rajewsky N. Deep conservation of microRNA-target relationships and 3′UTR motifs in vertebrates, flies, and nematodes. Cold Spring Harb Symp Quant Biol 2006;71:149-156.
-
(2006)
Cold Spring Harb Symp Quant Biol
, vol.71
, pp. 149-156
-
-
Chen, K.1
Rajewsky, N.2
-
21
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel D. MicroRNAs: target recognition and regulatory functions. Cell 2009;136:215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.1
-
22
-
-
40849108663
-
Selective blockade of microRNA processing by Lin28
-
Viswanathan SR, Daley GQ, Gregory RI. Selective blockade of microRNA processing by Lin28. Science 2008;320:97-100.
-
(2008)
Science
, vol.320
, pp. 97-100
-
-
Viswanathan, S.R.1
Daley, G.Q.2
Gregory, R.I.3
-
23
-
-
53949088050
-
Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA
-
Heo I, Joo C, Cho J, Ha M, Han J, Kim V. Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA. Mol Cell 2008;32:276-284.
-
(2008)
Mol Cell
, vol.32
, pp. 276-284
-
-
Heo, I.1
Joo, C.2
Cho, J.3
Ha, M.4
Han, J.5
Kim, V.6
-
24
-
-
47949100595
-
Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
-
Newman M, Thomson J, Hammond S. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 2008;14:1539-1549.
-
(2008)
RNA
, vol.14
, pp. 1539-1549
-
-
Newman, M.1
Thomson, J.2
Hammond, S.3
-
25
-
-
52049124806
-
Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28
-
Piskounova E, et al. Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J Biol Chem 2008;283:21310-21314.
-
(2008)
J Biol Chem
, vol.283
, pp. 21310-21314
-
-
Piskounova, E.1
-
26
-
-
77954144740
-
Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies
-
Zhu H, et al. Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies. Nat Genet 2010;42:626-656.
-
(2010)
Nat Genet
, vol.42
, pp. 626-656
-
-
Zhu, H.1
-
27
-
-
42649092874
-
Identification of ten loci associated with height highlights new biological pathways in human growth
-
Lettre G, et al. Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet 2008;40:584-591.
-
(2008)
Nat Genet
, vol.40
, pp. 584-591
-
-
Lettre, G.1
-
28
-
-
66649105485
-
Genetic variation in LIN28B is associated with the timing of puberty
-
Ong KK, et al. Genetic variation in LIN28B is associated with the timing of puberty. Nat Genet 2009;41:729-733.
-
(2009)
Nat Genet
, vol.41
, pp. 729-733
-
-
Ong, K.K.1
-
29
-
-
66649116283
-
Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche
-
Sulem P, et al. Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche. Nat Genet 2009;41:734-738.
-
(2009)
Nat Genet
, vol.41
, pp. 734-738
-
-
Sulem, P.1
-
30
-
-
66649090056
-
Genome-wide association studies identify loci associated with age at menarche and age at natural menopause
-
He C, et al. Genome-wide association studies identify loci associated with age at menarche and age at natural menopause. Nat Genet 2009;41:724-728.
-
(2009)
Nat Genet
, vol.41
, pp. 724-728
-
-
He, C.1
-
31
-
-
66649123583
-
Meta-analysis of genome-wide association data identifies two loci influencing age at menarche
-
Perry JR, et al. Meta-analysis of genome-wide association data identifies two loci influencing age at menarche. Nat Genet 2009;41:648-650.
-
(2009)
Nat Genet
, vol.41
, pp. 648-650
-
-
Perry, J.R.1
-
32
-
-
80053481600
-
The Lin28/let-7 axis regulates glucose metabolism
-
Zhu H, et al. The Lin28/let-7 axis regulates glucose metabolism. Cell 2011;147:81-94.
-
(2011)
Cell
, vol.147
, pp. 81-94
-
-
Zhu, H.1
-
33
-
-
53749098061
-
Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression
-
Nishino J, Kim I, Chada K, Morrison S. Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression. Cell 2008;135:227-239.
-
(2008)
Cell
, vol.135
, pp. 227-239
-
-
Nishino, J.1
Kim, I.2
Chada, K.3
Morrison, S.4
-
34
-
-
77049099101
-
Lin28: a microRNA regulator with a macro role
-
Viswanathan S, Daley G. Lin28: a microRNA regulator with a macro role. Cell 2010;140:445-449.
-
(2010)
Cell
, vol.140
, pp. 445-449
-
-
Viswanathan, S.1
Daley, G.2
-
35
-
-
84865589321
-
How does Lin28 let-7 control development and disease?
-
Thornton J, Gregory R. How does Lin28 let-7 control development and disease? Trends Cell Biol 2012;22:474-482.
-
(2012)
Trends Cell Biol
, vol.22
, pp. 474-482
-
-
Thornton, J.1
Gregory, R.2
-
36
-
-
34247896991
-
Ontogeny of the hematopoietic system
-
Cumano A, Godin I. Ontogeny of the hematopoietic system. Annu Rev Immunol 2007;25:745-785.
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 745-785
-
-
Cumano, A.1
Godin, I.2
-
37
-
-
0019934858
-
Demonstration of a cyclic renewal of the lymphocyte precursor cells in the quail thymus during embryonic and perinatal life
-
Jotereau F, Le Douarin N. Demonstration of a cyclic renewal of the lymphocyte precursor cells in the quail thymus during embryonic and perinatal life. J Immunol 1982;129:1869-1877.
-
(1982)
J Immunol
, vol.129
, pp. 1869-1877
-
-
Jotereau, F.1
Le Douarin, N.2
-
38
-
-
0016806926
-
Tracing of cells of the avian thymus through embryonic life in interspecific chimeras
-
Le Douarin N, Jotereau F. Tracing of cells of the avian thymus through embryonic life in interspecific chimeras. J Exp Med 1975;142:17-40.
-
(1975)
J Exp Med
, vol.142
, pp. 17-40
-
-
Le Douarin, N.1
Jotereau, F.2
-
39
-
-
0021838305
-
Progenitors for Ly-1 B cells are distinct from progenitors for other B cells
-
Hayakawa K, Hardy R, Herzenberg L. Progenitors for Ly-1 B cells are distinct from progenitors for other B cells. J Exp Med 1985;161:1554-1568.
-
(1985)
J Exp Med
, vol.161
, pp. 1554-1568
-
-
Hayakawa, K.1
Hardy, R.2
Herzenberg, L.3
-
40
-
-
0025062703
-
A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells
-
Ikuta K, et al. A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells. Cell 1990;62:863-874.
-
(1990)
Cell
, vol.62
, pp. 863-874
-
-
Ikuta, K.1
-
41
-
-
0024851881
-
Toward a layered immune system
-
Herzenberg LA. Toward a layered immune system. Cell 1989;59:953-954.
-
(1989)
Cell
, vol.59
, pp. 953-954
-
-
Herzenberg, L.A.1
-
42
-
-
0026730855
-
Layered evolution in the immune system. A model for the ontogeny and development of multiple lymphocyte lineages
-
Herzenberg LA, Kantor AB. Layered evolution in the immune system. A model for the ontogeny and development of multiple lymphocyte lineages. Ann NY Acad Sci 1992;651:1-9.
-
(1992)
Ann NY Acad Sci
, vol.651
, pp. 1-9
-
-
Herzenberg, L.A.1
Kantor, A.B.2
-
43
-
-
33748875713
-
B lymphocytes from early vertebrates have potent phagocytic and microbicidal abilities
-
Li J, et al. B lymphocytes from early vertebrates have potent phagocytic and microbicidal abilities. Nat Immunol 2006;7:1116-1124.
-
(2006)
Nat Immunol
, vol.7
, pp. 1116-1124
-
-
Li, J.1
-
44
-
-
0023845959
-
A large subpopulation of avian T cells express a homologue of the mammalian T gamma/delta receptor
-
Sowder JT, Chen CL, Ager LL, Chan MM, Cooper MD. A large subpopulation of avian T cells express a homologue of the mammalian T gamma/delta receptor. J Exp Med 1988;167:315-322.
-
(1988)
J Exp Med
, vol.167
, pp. 315-322
-
-
Sowder, J.T.1
Chen, C.L.2
Ager, L.L.3
Chan, M.M.4
Cooper, M.D.5
-
45
-
-
79952140062
-
Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential
-
Yoshimoto M, et al. Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential. Proc Natl Acad Sci U S A 2011;108:1468-1473.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 1468-1473
-
-
Yoshimoto, M.1
-
46
-
-
0242442687
-
Age-dependent requirement for gammadelta T cells in the primary but not secondary protective immune response against an intestinal parasite
-
Ramsburg E, Tigelaar R, Craft J, Hayday A. Age-dependent requirement for gammadelta T cells in the primary but not secondary protective immune response against an intestinal parasite. J Exp Med 2003;198:1403-1414.
-
(2003)
J Exp Med
, vol.198
, pp. 1403-1414
-
-
Ramsburg, E.1
Tigelaar, R.2
Craft, J.3
Hayday, A.4
-
47
-
-
79960783082
-
At the crossroads between tolerance and aggression: revisiting the "layered immune system" hypothesis
-
Mold J, McCune J. At the crossroads between tolerance and aggression: revisiting the "layered immune system" hypothesis. Chimerism 2011;2:35-41.
-
(2011)
Chimerism
, vol.2
, pp. 35-41
-
-
Mold, J.1
McCune, J.2
-
48
-
-
78650352931
-
Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans
-
Mold J, et al. Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans. Science 2010;330:1695-1699.
-
(2010)
Science
, vol.330
, pp. 1695-1699
-
-
Mold, J.1
-
49
-
-
33845188143
-
Developmental switch of mouse hematopoietic stem cells from fetal to adult type occurs in bone marrow after birth
-
Kikuchi K, Kondo M. Developmental switch of mouse hematopoietic stem cells from fetal to adult type occurs in bone marrow after birth. Proc Natl Acad Sci USA 2006;103:17852-17857.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17852-17857
-
-
Kikuchi, K.1
Kondo, M.2
-
50
-
-
34249679309
-
Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties
-
Bowie MB, et al. Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties. Proc Natl Acad Sci USA 2007;104:5878-5882.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5878-5882
-
-
Bowie, M.B.1
-
51
-
-
84866064701
-
Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression
-
Magee J, Ikenoue T, Nakada D, Lee J, Guan K-L, Morrison S. Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression. Cell Stem Cell 2012;11:415-428.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 415-428
-
-
Magee, J.1
Ikenoue, T.2
Nakada, D.3
Lee, J.4
Guan, K.-L.5
Morrison, S.6
-
52
-
-
0026059304
-
The junctional modifications of a T cell receptor gamma chain are determined at the level of thymic precursors
-
Ikuta K, Weissman IL. The junctional modifications of a T cell receptor gamma chain are determined at the level of thymic precursors. J Exp Med 1991;174:1279-1282.
-
(1991)
J Exp Med
, vol.174
, pp. 1279-1282
-
-
Ikuta, K.1
Weissman, I.L.2
-
53
-
-
0025184095
-
Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences
-
Feeney A. Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences. J Exp Med 1990;172:1377-1390.
-
(1990)
J Exp Med
, vol.172
, pp. 1377-1390
-
-
Feeney, A.1
-
54
-
-
0027369562
-
Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes
-
Komori T, Okada A, Stewart V, Alt FW. Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes. Science 1993;261:1171.
-
(1993)
Science
, vol.261
, pp. 1171
-
-
Komori, T.1
Okada, A.2
Stewart, V.3
Alt, F.W.4
-
55
-
-
34547668398
-
Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells
-
Kim I, Saunders TL, Morrison SJ. Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells. Cell 2007;130:470-483.
-
(2007)
Cell
, vol.130
, pp. 470-483
-
-
Kim, I.1
Saunders, T.L.2
Morrison, S.J.3
-
56
-
-
77953915915
-
Regulation of microRNA expression and abundance during lymphopoiesis
-
Kuchen S, et al. Regulation of microRNA expression and abundance during lymphopoiesis. Immunity 2010;32:828-839.
-
(2010)
Immunity
, vol.32
, pp. 828-839
-
-
Kuchen, S.1
-
57
-
-
72549098210
-
Let-7 microRNAs are developmentally regulated in circulating human erythroid cells
-
Noh S-J, et al. Let-7 microRNAs are developmentally regulated in circulating human erythroid cells. J Transl Med 2009;7:98.
-
(2009)
J Transl Med
, vol.7
, pp. 98
-
-
Noh, S.-J.1
-
58
-
-
84864563641
-
Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines, and peripheral T-cell lymphoma
-
Beachy S, et al. Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines, and peripheral T-cell lymphoma. Blood 2012;120:1048-1059.
-
(2012)
Blood
, vol.120
, pp. 1048-1059
-
-
Beachy, S.1
-
59
-
-
84868526281
-
Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B
-
Rao S, et al. Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B. Blood 2012;120:3764-3773.
-
(2012)
Blood
, vol.120
, pp. 3764-3773
-
-
Rao, S.1
-
60
-
-
50549095181
-
let-7 microRNAs in development, stem cells and cancer
-
Bussing I, Slack FJ, Grosshans H. let-7 microRNAs in development, stem cells and cancer. Trends Mol Med 2008;14:400-409.
-
(2008)
Trends Mol Med
, vol.14
, pp. 400-409
-
-
Bussing, I.1
Slack, F.J.2
Grosshans, H.3
-
61
-
-
60549104367
-
Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7
-
Dangi-Garimella S, et al. Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO 2009;28:347-358.
-
(2009)
EMBO
, vol.28
, pp. 347-358
-
-
Dangi-Garimella, S.1
-
62
-
-
62549160957
-
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation
-
Chang T-C, et al. Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci USA 2009;106:3384-3389.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3384-3389
-
-
Chang, T.-C.1
-
63
-
-
20944450160
-
Combinatorial microRNA target predictions
-
Krek A, et al. Combinatorial microRNA target predictions. Nat Genet 2005;37:495-500.
-
(2005)
Nat Genet
, vol.37
, pp. 495-500
-
-
Krek, A.1
-
64
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005;120:15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
65
-
-
34247593034
-
Impaired microRNA processing enhances cellular transformation and tumorigenesis
-
Kumar M, Lu J, Mercer K, Golub T, Jacks T. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet 2007;39:673-677.
-
(2007)
Nat Genet
, vol.39
, pp. 673-677
-
-
Kumar, M.1
Lu, J.2
Mercer, K.3
Golub, T.4
Jacks, T.5
-
66
-
-
70350778443
-
An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation
-
Iliopoulos D, Hirsch H, Struhl K. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell 2009;139:693-706.
-
(2009)
Cell
, vol.139
, pp. 693-706
-
-
Iliopoulos, D.1
Hirsch, H.2
Struhl, K.3
-
67
-
-
78650722292
-
MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets
-
Ooi AG, Sahoo D, Adorno M, Wang Y, Weissman IL, Park CY. MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets. Proc Natl Acad Sci USA 2010;107:21505-21510.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 21505-21510
-
-
Ooi, A.G.1
Sahoo, D.2
Adorno, M.3
Wang, Y.4
Weissman, I.L.5
Park, C.Y.6
-
68
-
-
84858257170
-
Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A
-
Chaudhuri A, et al. Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A. Proc Natl Acad Sci USA 2012;109:4233-4238.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 4233-4238
-
-
Chaudhuri, A.1
-
69
-
-
84855421472
-
Allain Fdr. Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28
-
Loughlin F, Gebert L, Towbin H, Brunschweiger A, Hall J. Allain Fdr. Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28. Nat Struct Mol Biol 2012;19:84-93.
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 84-93
-
-
Loughlin, F.1
Gebert, L.2
Towbin, H.3
Brunschweiger, A.4
Hall, J.5
-
70
-
-
81855228621
-
Molecular basis for interaction of let-7 microRNAs with Lin28
-
Nam Y, Chen C, Gregory R, Chou J, Sliz P. Molecular basis for interaction of let-7 microRNAs with Lin28. Cell 2011;147:1080-1091.
-
(2011)
Cell
, vol.147
, pp. 1080-1091
-
-
Nam, Y.1
Chen, C.2
Gregory, R.3
Chou, J.4
Sliz, P.5
-
71
-
-
84863806564
-
A mirror of two faces: Lin28 as a master regulator of both miRNA and mRNA
-
Huang Y. A mirror of two faces: Lin28 as a master regulator of both miRNA and mRNA. Wiley Interdiscip Rev RNA 2012;3:483-494.
-
(2012)
Wiley Interdiscip Rev RNA
, vol.3
, pp. 483-494
-
-
Huang, Y.1
-
72
-
-
77950357078
-
LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro
-
Balzer E, Heine C, Jiang Q, Lee V, Moss E. LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro. Development 2010;137:891-900.
-
(2010)
Development
, vol.137
, pp. 891-900
-
-
Balzer, E.1
Heine, C.2
Jiang, Q.3
Lee, V.4
Moss, E.5
-
73
-
-
77955425756
-
Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis
-
Michlewski G, Caceres JF. Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Nat Struct Mol Biol 2010;17:1011-1018.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1011-1018
-
-
Michlewski, G.1
Caceres, J.F.2
-
74
-
-
34447530917
-
Localization of the developmental timing regulator Lin28 to mRNP complexes P-bodies and stress granules
-
Balzer E, Moss E. Localization of the developmental timing regulator Lin28 to mRNP complexes P-bodies and stress granules. RNA Biol 2007;4:16-25.
-
(2007)
RNA Biol
, vol.4
, pp. 16-25
-
-
Balzer, E.1
Moss, E.2
-
75
-
-
34247589770
-
Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency
-
Polesskaya A, Cuvellier S, Naguibneva I, Duquet A, Moss E, Harel-Bellan A. Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency. Genes Dev 2007;21:1125-1163.
-
(2007)
Genes Dev
, vol.21
, pp. 1125-1163
-
-
Polesskaya, A.1
Cuvellier, S.2
Naguibneva, I.3
Duquet, A.4
Moss, E.5
Harel-Bellan, A.6
-
76
-
-
84855518254
-
Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs
-
Frost R, Olson E. Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs. Proc Natl Acad Sci U S A 2011;108:21075-21080.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 21075-21080
-
-
Frost, R.1
Olson, E.2
-
77
-
-
84868160135
-
LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance
-
Wilbert M, et al. LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance. Mol Cell 2012;48:195-206.
-
(2012)
Mol Cell
, vol.48
, pp. 195-206
-
-
Wilbert, M.1
-
78
-
-
84869086143
-
LIN28A is a suppressor of ER-associated translation in embryonic stem cells
-
Cho J, et al. LIN28A is a suppressor of ER-associated translation in embryonic stem cells. Cell 2012;151:765-777.
-
(2012)
Cell
, vol.151
, pp. 765-777
-
-
Cho, J.1
-
79
-
-
84859735682
-
HMGA1 is a novel downstream nuclear target of the insulin receptor signaling pathway
-
Chiefari E, et al. HMGA1 is a novel downstream nuclear target of the insulin receptor signaling pathway. Sci Rep 2012;2:251.
-
(2012)
Sci Rep
, vol.2
, pp. 251
-
-
Chiefari, E.1
-
80
-
-
79953015943
-
Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells
-
Peng S, et al. Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells. Stem Cells 2011;29:496-504.
-
(2011)
Stem Cells
, vol.29
, pp. 496-504
-
-
Peng, S.1
-
81
-
-
22944433872
-
Aberrant T cell differentiation in the absence of Dicer
-
Muljo S, Ansel K, Kanellopoulou C, Livingston D, Rao A, Rajewsky K. Aberrant T cell differentiation in the absence of Dicer. J Exp Med 2005;202:261-269.
-
(2005)
J Exp Med
, vol.202
, pp. 261-269
-
-
Muljo, S.1
Ansel, K.2
Kanellopoulou, C.3
Livingston, D.4
Rao, A.5
Rajewsky, K.6
-
82
-
-
20844432885
-
T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer
-
Cobb BS, et al. T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer. J Exp Med 2005;201:1367-1373.
-
(2005)
J Exp Med
, vol.201
, pp. 1367-1373
-
-
Cobb, B.S.1
-
83
-
-
51049089025
-
The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease
-
Chong M, Rasmussen J, Rudensky A, Rundensky A, Littman D. The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease. J Exp Med 2008;205:2005-2017.
-
(2008)
J Exp Med
, vol.205
, pp. 2005-2017
-
-
Chong, M.1
Rasmussen, J.2
Rudensky, A.3
Rundensky, A.4
Littman, D.5
-
84
-
-
33750499991
-
A role for Dicer in immune regulation
-
Cobb BS, et al. A role for Dicer in immune regulation. J Exp Med 2006;203:2519-2527.
-
(2006)
J Exp Med
, vol.203
, pp. 2519-2527
-
-
Cobb, B.S.1
-
85
-
-
39749101294
-
Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage
-
Koralov S, et al. Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage. Cell 2008;132:860-874.
-
(2008)
Cell
, vol.132
, pp. 860-874
-
-
Koralov, S.1
-
86
-
-
79960455119
-
A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing
-
Babiarz JE, Hsu R, Melton C, Thomas M, Ullian EM, Blelloch R. A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing. RNA 2011;17:1489-1501.
-
(2011)
RNA
, vol.17
, pp. 1489-1501
-
-
Babiarz, J.E.1
Hsu, R.2
Melton, C.3
Thomas, M.4
Ullian, E.M.5
Blelloch, R.6
-
87
-
-
54349104464
-
Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent Dicer-dependent small RNAs
-
Babiarz JE, Ruby JG, Wang Y, Bartel DP, Blelloch R. Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent Dicer-dependent small RNAs. Genes Dev 2008;22:2773-2785.
-
(2008)
Genes Dev
, vol.22
, pp. 2773-2785
-
-
Babiarz, J.E.1
Ruby, J.G.2
Wang, Y.3
Bartel, D.P.4
Blelloch, R.5
-
88
-
-
77956278269
-
Canonical and alternate functions of the microRNA biogenesis machinery
-
Chong M, Zhang G, Cheloufi S, Neubert T, Hannon G, Littman D. Canonical and alternate functions of the microRNA biogenesis machinery. Genes Dev 2010;24:1951-1960.
-
(2010)
Genes Dev
, vol.24
, pp. 1951-1960
-
-
Chong, M.1
Zhang, G.2
Cheloufi, S.3
Neubert, T.4
Hannon, G.5
Littman, D.6
-
89
-
-
33847323881
-
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal
-
Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R. DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet 2007;39:380-385.
-
(2007)
Nat Genet
, vol.39
, pp. 380-385
-
-
Wang, Y.1
Medvid, R.2
Melton, C.3
Jaenisch, R.4
Blelloch, R.5
-
90
-
-
77953183812
-
A dicer-independent miRNA biogenesis pathway that requires Ago catalysis
-
Cheloufi S, Dos Santos C, Chong M, Hannon G. A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature 2010;465:584-589.
-
(2010)
Nature
, vol.465
, pp. 584-589
-
-
Cheloufi, S.1
Dos Santos, C.2
Chong, M.3
Hannon, G.4
-
91
-
-
77953897182
-
A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity
-
Cifuentes D, et al. A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity. Science 2010;328:1694-1698.
-
(2010)
Science
, vol.328
, pp. 1694-1698
-
-
Cifuentes, D.1
-
92
-
-
84869088655
-
DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation
-
Hu Q, et al. DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation. Nat Struct Mol Biol 2012;19:1168-1175.
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 1168-1175
-
-
Hu, Q.1
-
93
-
-
79952786337
-
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration
-
Kaneko H, et al. DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature 2011;471:325-330.
-
(2011)
Nature
, vol.471
, pp. 325-330
-
-
Kaneko, H.1
-
94
-
-
84860883878
-
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88
-
Tarallo V, et al. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell 2012;149:847-859.
-
(2012)
Cell
, vol.149
, pp. 847-859
-
-
Tarallo, V.1
-
95
-
-
44349159416
-
Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes
-
Tam OH, et al. Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes. Nature 2008;453:534-538.
-
(2008)
Nature
, vol.453
, pp. 534-538
-
-
Tam, O.H.1
-
96
-
-
44349130233
-
Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes
-
Watanabe T, et al. Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature 2008;453:539-543.
-
(2008)
Nature
, vol.453
, pp. 539-543
-
-
Watanabe, T.1
-
97
-
-
58149097010
-
Posttranscriptional crossregulation between Drosha and DGCR8
-
Han J, et al. Posttranscriptional crossregulation between Drosha and DGCR8. Cell 2009;136:75-84.
-
(2009)
Cell
, vol.136
, pp. 75-84
-
-
Han, J.1
-
98
-
-
62549120015
-
Genome-wide identification of targets of the drosha-pasha/DGCR8 complex
-
Kadener S, et al. Genome-wide identification of targets of the drosha-pasha/DGCR8 complex. RNA 2009;15:537-545.
-
(2009)
RNA
, vol.15
, pp. 537-545
-
-
Kadener, S.1
-
99
-
-
66449118741
-
Post-transcriptional control of DGCR8 expression by the Microprocessor
-
Triboulet R, Chang HM, Lapierre RJ, Gregory RI. Post-transcriptional control of DGCR8 expression by the Microprocessor. RNA 2009;15:1005-1011.
-
(2009)
RNA
, vol.15
, pp. 1005-1011
-
-
Triboulet, R.1
Chang, H.M.2
Lapierre, R.J.3
Gregory, R.I.4
-
100
-
-
84862879743
-
Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs
-
Knuckles P, et al. Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs. Nat Neurosci 2012;15:962-969.
-
(2012)
Nat Neurosci
, vol.15
, pp. 962-969
-
-
Knuckles, P.1
-
101
-
-
0942279635
-
RNAi-mediated targeting of heterochromatin by the RITS complex
-
Verdel A, et al. RNAi-mediated targeting of heterochromatin by the RITS complex. Science 2004;303:672-676.
-
(2004)
Science
, vol.303
, pp. 672-676
-
-
Verdel, A.1
-
102
-
-
0038738781
-
RNA interference is required for normal centromere function in fission yeast
-
Volpe T, et al. RNA interference is required for normal centromere function in fission yeast. Chromosome Res 2003;11:137-146.
-
(2003)
Chromosome Res
, vol.11
, pp. 137-146
-
-
Volpe, T.1
-
103
-
-
13844294261
-
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
-
Kanellopoulou C, et al. Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev 2005;19:489-501.
-
(2005)
Genes Dev
, vol.19
, pp. 489-501
-
-
Kanellopoulou, C.1
-
104
-
-
38349118916
-
RNA-binding protein Dnd1 inhibits microRNA access to target mRNA
-
Kedde M, et al. RNA-binding protein Dnd1 inhibits microRNA access to target mRNA. Cell 2007;131:1273-1286.
-
(2007)
Cell
, vol.131
, pp. 1273-1286
-
-
Kedde, M.1
-
105
-
-
68149165414
-
HuR recruits let-7/RISC to repress c-Myc expression
-
Kim H, Kuwano Y, Srikantan S, Lee E, Martindale J, Gorospe M. HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev 2009;23:1743-1748.
-
(2009)
Genes Dev
, vol.23
, pp. 1743-1748
-
-
Kim, H.1
Kuwano, Y.2
Srikantan, S.3
Lee, E.4
Martindale, J.5
Gorospe, M.6
-
106
-
-
34249875986
-
Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation
-
Liao B, Hu Y, Brewer G. Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation. Nat Struct Mol Biol 2007;14:511-518.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 511-518
-
-
Liao, B.1
Hu, Y.2
Brewer, G.3
-
107
-
-
0030969572
-
A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer
-
Min H, Turck CW, Nikolic JM, Black DL. A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer. Genes Dev 1997;11:1023-1036.
-
(1997)
Genes Dev
, vol.11
, pp. 1023-1036
-
-
Min, H.1
Turck, C.W.2
Nikolic, J.M.3
Black, D.L.4
-
108
-
-
79961159449
-
Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection
-
Lin W-J, et al. Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection. Mol Cell Biol 2011;31:3196-3207.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 3196-3207
-
-
Lin, W.-J.1
-
109
-
-
79952770568
-
Deletion of tristetraprolin caused spontaneous reactive granulopoiesis by a non-cell-autonomous mechanism without disturbing long-term hematopoietic stem cell quiescence
-
Kaplan IM, Morisot S, Heiser D, Cheng WC, Kim MJ, Civin CI. Deletion of tristetraprolin caused spontaneous reactive granulopoiesis by a non-cell-autonomous mechanism without disturbing long-term hematopoietic stem cell quiescence. J Immunol 2011;186:2826-2834.
-
(2011)
J Immunol
, vol.186
, pp. 2826-2834
-
-
Kaplan, I.M.1
Morisot, S.2
Heiser, D.3
Cheng, W.C.4
Kim, M.J.5
Civin, C.I.6
-
110
-
-
0034254553
-
TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha
-
Piecyk M, et al. TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha. EMBO 2000;19:4154-4163.
-
(2000)
EMBO
, vol.19
, pp. 4154-4163
-
-
Piecyk, M.1
-
111
-
-
0034657357
-
Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation
-
Chen CY, et al. Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation. Genes Dev 2000;14:1236-1248.
-
(2000)
Genes Dev
, vol.14
, pp. 1236-1248
-
-
Chen, C.Y.1
-
112
-
-
72849128981
-
Essential role of the RNA-binding protein HuR in progenitor cell survival in mice
-
Ghosh M, et al. Essential role of the RNA-binding protein HuR in progenitor cell survival in mice. J Clin Invest 2009;119:3530-3543.
-
(2009)
J Clin Invest
, vol.119
, pp. 3530-3543
-
-
Ghosh, M.1
-
114
-
-
77958074159
-
ZFP36L1 negatively regulates erythroid differentiation of CD34 + hematopoietic stem cells by interfering with the Stat5b pathway
-
Vignudelli T, et al. ZFP36L1 negatively regulates erythroid differentiation of CD34 + hematopoietic stem cells by interfering with the Stat5b pathway. Mol Biol Cell 2010;21:3340-3351.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 3340-3351
-
-
Vignudelli, T.1
-
115
-
-
79958279101
-
KSRP promotes the maturation of a group of miRNA precursors
-
Trabucchi M, Briata P, Filipowicz W, Ramos A, Gherzi R, Rosenfeld M. KSRP promotes the maturation of a group of miRNA precursors. Adv Exp Med Biol 2010;700:36-42.
-
(2010)
Adv Exp Med Biol
, vol.700
, pp. 36-42
-
-
Trabucchi, M.1
Briata, P.2
Filipowicz, W.3
Ramos, A.4
Gherzi, R.5
Rosenfeld, M.6
-
116
-
-
67649277689
-
The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs
-
Trabucchi M, et al. The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature 2009;459:1010-1014.
-
(2009)
Nature
, vol.459
, pp. 1010-1014
-
-
Trabucchi, M.1
-
117
-
-
79951500251
-
The ATM kinase induces microRNA biogenesis in the DNA damage response
-
Zhang X, Wan G, Berger F, He X, Lu X. The ATM kinase induces microRNA biogenesis in the DNA damage response. Mol Cell 2011;41:371-383.
-
(2011)
Mol Cell
, vol.41
, pp. 371-383
-
-
Zhang, X.1
Wan, G.2
Berger, F.3
He, X.4
Lu, X.5
-
118
-
-
70349323601
-
LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages
-
Ruggiero T, et al. LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. FASEB J 2009;23:2898-2908.
-
(2009)
FASEB J
, vol.23
, pp. 2898-2908
-
-
Ruggiero, T.1
-
119
-
-
33846354928
-
The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling
-
Gherzi R, et al. The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling. PLoS Biol 2006;5:e5.
-
(2006)
PLoS Biol
, vol.5
-
-
Gherzi, R.1
-
121
-
-
2942612333
-
A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery
-
Gherzi R, et al. A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery. Mol Cell 2004;14:571-583.
-
(2004)
Mol Cell
, vol.14
, pp. 571-583
-
-
Gherzi, R.1
-
122
-
-
84861969926
-
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
-
Castello A, et al. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 2012;149:1393-1406.
-
(2012)
Cell
, vol.149
, pp. 1393-1406
-
-
Castello, A.1
-
123
-
-
84861997955
-
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts
-
Baltz AG, et al. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol Cell 2012;46:674-690.
-
(2012)
Mol Cell
, vol.46
, pp. 674-690
-
-
Baltz, A.G.1
-
124
-
-
0036529621
-
Comparative genomics and evolution of proteins involved in RNA metabolism
-
Anantharaman V, Koonin E, Aravind L. Comparative genomics and evolution of proteins involved in RNA metabolism. Nucleic Acids Res 2002;30:1427-1464.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 1427-1464
-
-
Anantharaman, V.1
Koonin, E.2
Aravind, L.3
-
125
-
-
44149104364
-
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements
-
Weischenfeldt J, et al. NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements. Genes Dev 2008;22:1381-1396.
-
(2008)
Genes Dev
, vol.22
, pp. 1381-1396
-
-
Weischenfeldt, J.1
-
126
-
-
79960612825
-
Perturbation of thymocyte development in nonsense-mediated decay (NMD)-deficient mice
-
Frischmeyer-Guerrerio P, et al. Perturbation of thymocyte development in nonsense-mediated decay (NMD)-deficient mice. Proc Natl Acad Sci U S A 2011;108:10638-10643.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 10638-10643
-
-
Frischmeyer-Guerrerio, P.1
-
127
-
-
66349122954
-
Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing
-
Li J, et al. Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing. Science 2009;324:1210-1213.
-
(2009)
Science
, vol.324
, pp. 1210-1213
-
-
Li, J.1
-
128
-
-
69949154245
-
Zcchc11-dependent uridylation of microRNA directs cytokine expression
-
Jones M, et al. Zcchc11-dependent uridylation of microRNA directs cytokine expression. Nat Cell Biol 2009;11:1157-1163.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1157-1163
-
-
Jones, M.1
-
129
-
-
68749102148
-
TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation
-
Heo I, et al. TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell 2009;138:696-708.
-
(2009)
Cell
, vol.138
, pp. 696-708
-
-
Heo, I.1
-
130
-
-
70349820140
-
Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells
-
Hagan JP, Piskounova E, Gregory RI. Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells. Nat Struct Mol Biol 2009;16:1021-1025.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 1021-1025
-
-
Hagan, J.P.1
Piskounova, E.2
Gregory, R.I.3
-
131
-
-
70349810911
-
LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans
-
Lehrbach NJ, et al. LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans. Nat Struct Mol Biol 2009;16:1016-1020.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 1016-1020
-
-
Lehrbach, N.J.1
-
132
-
-
84867553154
-
Human RNA methyltransferase BCDIN3D regulates microRNA rrocessing
-
Xhemalce B, Robson S, Kouzarides T. Human RNA methyltransferase BCDIN3D regulates microRNA rrocessing. Cell 2012;151:278-288.
-
(2012)
Cell
, vol.151
, pp. 278-288
-
-
Xhemalce, B.1
Robson, S.2
Kouzarides, T.3
-
133
-
-
34547820319
-
Transcriptional networking cap-tures the 7SK RNA 5′-gamma-methyltransferase
-
Shuman S. Transcriptional networking cap-tures the 7SK RNA 5′-gamma-methyltransferase. Mol Cell 2007;27:517-519.
-
(2007)
Mol Cell
, vol.27
, pp. 517-519
-
-
Shuman, S.1
-
134
-
-
72949123583
-
Post-transcriptional regulons coordinate the initiation and resolution of inflammation
-
Anderson P. Post-transcriptional regulons coordinate the initiation and resolution of inflammation. Nat Rev Immunol 2010;10:24-35.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 24-35
-
-
Anderson, P.1
-
135
-
-
78649558664
-
mRNA degradation plays a significant role in the program of gene expression regulated by phosphatidylinositol 3-kinase signaling
-
Graham J, Hendershott M, Terragni J, Cooper G. mRNA degradation plays a significant role in the program of gene expression regulated by phosphatidylinositol 3-kinase signaling. Mol Cell Biol 2010;30:5295-5305.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 5295-5305
-
-
Graham, J.1
Hendershott, M.2
Terragni, J.3
Cooper, G.4
-
136
-
-
19944426618
-
The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B
-
Schmidlin M, et al. The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B. EMBO 2004;23:4760-4769.
-
(2004)
EMBO
, vol.23
, pp. 4760-4769
-
-
Schmidlin, M.1
-
137
-
-
79952142751
-
ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes
-
Mazan-Mamczarz K, et al. ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes. Blood 2011;117:2441-2450.
-
(2011)
Blood
, vol.117
, pp. 2441-2450
-
-
Mazan-Mamczarz, K.1
-
138
-
-
84872115037
-
Posttranscriptional regulation of gene expression-adding another layer of complexity to the DNA damage response
-
Boucas J, et al. Posttranscriptional regulation of gene expression-adding another layer of complexity to the DNA damage response. Front Genet 2012;3:159.
-
(2012)
Front Genet
, vol.3
, pp. 159
-
-
Boucas, J.1
-
139
-
-
0033553624
-
Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling
-
Sabatini D, et al. Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling. Science 1999;284:1161-1164.
-
(1999)
Science
, vol.284
, pp. 1161-1164
-
-
Sabatini, D.1
-
140
-
-
34548754592
-
Tristetraprolin, a negative regulator of mRNA stability, is increased in old B cells and is involved in the degradation of E47 mRNA
-
Frasca D, Landin A, Alvarez J, Blackshear P, Riley R, Blomberg B. Tristetraprolin, a negative regulator of mRNA stability, is increased in old B cells and is involved in the degradation of E47 mRNA. J Immunol 2007;179:918-927.
-
(2007)
J Immunol
, vol.179
, pp. 918-927
-
-
Frasca, D.1
Landin, A.2
Alvarez, J.3
Blackshear, P.4
Riley, R.5
Blomberg, B.6
-
141
-
-
25444484963
-
Control of gene expression during T cell activation: alternate regulation of mRNA transcription and mRNA stability
-
Cheadle C, et al. Control of gene expression during T cell activation: alternate regulation of mRNA transcription and mRNA stability. BMC Genom 2005;6:75.
-
(2005)
BMC Genom
, vol.6
, pp. 75
-
-
Cheadle, C.1
-
142
-
-
33646881121
-
Functional and molecular comparison of anergic and regulatory T lymphocytes
-
Knoechel B, et al. Functional and molecular comparison of anergic and regulatory T lymphocytes. J Immunol 2006;176:6473-6483.
-
(2006)
J Immunol
, vol.176
, pp. 6473-6483
-
-
Knoechel, B.1
-
143
-
-
7944225681
-
Patterns of coordinate down-regulation of ARE-containing transcripts following immune cell activation
-
Raghavan A, et al. Patterns of coordinate down-regulation of ARE-containing transcripts following immune cell activation. Genomics 2004;84:1002-1013.
-
(2004)
Genomics
, vol.84
, pp. 1002-1013
-
-
Raghavan, A.1
-
144
-
-
21544481148
-
Coordinate stabilization of growth-regulatory transcripts in T cell malignancies
-
Vlasova I, et al. Coordinate stabilization of growth-regulatory transcripts in T cell malignancies. Genomics 2005;86:159-171.
-
(2005)
Genomics
, vol.86
, pp. 159-171
-
-
Vlasova, I.1
-
145
-
-
78751705190
-
Posttranscriptional silencing of effector cytokine mRNA underlies the anergic phenotype of self-reactive T cells
-
Villarino A, et al. Posttranscriptional silencing of effector cytokine mRNA underlies the anergic phenotype of self-reactive T cells. Immunity 2011;34:50-60.
-
(2011)
Immunity
, vol.34
, pp. 50-60
-
-
Villarino, A.1
-
146
-
-
60749124122
-
The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules
-
Hao S, Baltimore D. The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules. Nat Immunol 2009;10:281-288.
-
(2009)
Nat Immunol
, vol.10
, pp. 281-288
-
-
Hao, S.1
Baltimore, D.2
-
147
-
-
84855916545
-
Protein-RNA interactions: new genomic technologies and perspectives
-
Konig J, Zarnack K, Luscombe NM, Ule J. Protein-RNA interactions: new genomic technologies and perspectives. Nat Rev Genet 2011;13:77-83.
-
(2011)
Nat Rev Genet
, vol.13
, pp. 77-83
-
-
Konig, J.1
Zarnack, K.2
Luscombe, N.M.3
Ule, J.4
-
148
-
-
79960230895
-
Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data
-
Zhang C, Darnell RB. Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data. Nat Biotechnol 2011;29:607-614.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 607-614
-
-
Zhang, C.1
Darnell, R.B.2
-
149
-
-
67749132423
-
Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
-
Chi SW, Zang JB, Mele A, Darnell RB. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 2009;460:479-486.
-
(2009)
Nature
, vol.460
, pp. 479-486
-
-
Chi, S.W.1
Zang, J.B.2
Mele, A.3
Darnell, R.B.4
-
150
-
-
76349122201
-
Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
-
Zisoulis DG, et al. Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans. Nat Struct Mol Biol 2010;17:173-179.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 173-179
-
-
Zisoulis, D.G.1
-
151
-
-
84869087484
-
CLIP-seq of eIF4AIII reveals transcriptome-wide mapping of the human exon junction complex
-
Sauliere J, et al. CLIP-seq of eIF4AIII reveals transcriptome-wide mapping of the human exon junction complex. Nat Struct Mol Biol 2012;19:1124-1131.
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 1124-1131
-
-
Sauliere, J.1
-
152
-
-
77950920903
-
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP
-
Hafner M, et al. Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell 2010;141:129-141.
-
(2010)
Cell
, vol.141
, pp. 129-141
-
-
Hafner, M.1
-
153
-
-
78650972252
-
Formation, regulation and evolution of Caenorhabditis elegans 3′UTRs
-
Jan CH, Friedman RC, Ruby JG, Bartel DP. Formation, regulation and evolution of Caenorhabditis elegans 3′UTRs. Nature 2011;469:97-101.
-
(2011)
Nature
, vol.469
, pp. 97-101
-
-
Jan, C.H.1
Friedman, R.C.2
Ruby, J.G.3
Bartel, D.P.4
-
154
-
-
47649124124
-
A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome
-
Sultan M, et al. A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome. Science 2008;321:956-960.
-
(2008)
Science
, vol.321
, pp. 956-960
-
-
Sultan, M.1
-
155
-
-
62549134121
-
Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling
-
Ingolia N, Ghaemmaghami S, Newman J, Weissman J. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science 2009;324:218-223.
-
(2009)
Science
, vol.324
, pp. 218-223
-
-
Ingolia, N.1
Ghaemmaghami, S.2
Newman, J.3
Weissman, J.4
-
156
-
-
84864453787
-
The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments
-
Ingolia N, Brar G, Rouskin S, McGeachy A, Weissman J. The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments. Nat Protoc 2012;7:1534-1550.
-
(2012)
Nat Protoc
, vol.7
, pp. 1534-1550
-
-
Ingolia, N.1
Brar, G.2
Rouskin, S.3
McGeachy, A.4
Weissman, J.5
-
157
-
-
80052978224
-
Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
-
Cabili MN, et al. Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. Genes Dev 2011;25:1915-1927.
-
(2011)
Genes Dev
, vol.25
, pp. 1915-1927
-
-
Cabili, M.N.1
-
158
-
-
84865727393
-
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression
-
Derrien T, et al. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res 2012;22:1775-1789.
-
(2012)
Genome Res
, vol.22
, pp. 1775-1789
-
-
Derrien, T.1
-
159
-
-
36248944103
-
Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation
-
Wan F, et al. Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation. Cell 2007;131:927-939.
-
(2007)
Cell
, vol.131
, pp. 927-939
-
-
Wan, F.1
-
160
-
-
33750044572
-
Purdy M, Marzluff W, Dominski Z. Characterization of 3′hExo, a 3′ exonuclease specifically interacting with the 3′ end of histone mRNA
-
X-c Y. Purdy M, Marzluff W, Dominski Z. Characterization of 3′hExo, a 3′ exonuclease specifically interacting with the 3′ end of histone mRNA. J Biol Chem 2006;281:30447-30454.
-
(2006)
J Biol Chem
, vol.281
, pp. 30447-30454
-
-
X-c, Y.1
-
161
-
-
70349237413
-
c-Myc is a target of RNA-binding motif protein 15 in the regulation of adult hematopoietic stem cell and megakaryocyte development
-
Niu C, Zhang J, Breslin P, Onciu M, Ma Z, Morris S. c-Myc is a target of RNA-binding motif protein 15 in the regulation of adult hematopoietic stem cell and megakaryocyte development. Blood 2009;114:2087-2096.
-
(2009)
Blood
, vol.114
, pp. 2087-2096
-
-
Niu, C.1
Zhang, J.2
Breslin, P.3
Onciu, M.4
Ma, Z.5
Morris, S.6
-
162
-
-
21444433242
-
Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D
-
Enokizono Y, et al. Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D. J Biol Chem 2005;280:18862-18870.
-
(2005)
J Biol Chem
, vol.280
, pp. 18862-18870
-
-
Enokizono, Y.1
-
163
-
-
34250306832
-
Nucleolin regulates gene expression in CD34-positive hematopoietic cells
-
Grinstein E, Du Y, Santourlidis S, Christ J, Uhrberg M, Wernet P. Nucleolin regulates gene expression in CD34-positive hematopoietic cells. J Biol Chem 2007;282:12439-12449.
-
(2007)
J Biol Chem
, vol.282
, pp. 12439-12449
-
-
Grinstein, E.1
Du, Y.2
Santourlidis, S.3
Christ, J.4
Uhrberg, M.5
Wernet, P.6
-
164
-
-
79961170994
-
A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?
-
Salmena L, Poliseno L, Tay Y, Kats L, Pandolfi PP. A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language? Cell 2011;146:353-358.
-
(2011)
Cell
, vol.146
, pp. 353-358
-
-
Salmena, L.1
Poliseno, L.2
Tay, Y.3
Kats, L.4
Pandolfi, P.P.5
-
165
-
-
77953957633
-
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
-
Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, Pandolfi PP. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 2010;465:1033-1038.
-
(2010)
Nature
, vol.465
, pp. 1033-1038
-
-
Poliseno, L.1
Salmena, L.2
Zhang, J.3
Carver, B.4
Haveman, W.J.5
Pandolfi, P.P.6
-
166
-
-
80054700538
-
Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs
-
Tay Y, et al. Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs. Cell 2011;147:344-357.
-
(2011)
Cell
, vol.147
, pp. 344-357
-
-
Tay, Y.1
-
167
-
-
80054681545
-
In vivo identification of tumor- suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma
-
Karreth FA, et al. In vivo identification of tumor- suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma. Cell 2011;147:382-395.
-
(2011)
Cell
, vol.147
, pp. 382-395
-
-
Karreth, F.A.1
-
168
-
-
80054689794
-
An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma
-
Sumazin P, et al. An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma. Cell 2011;147:370-381.
-
(2011)
Cell
, vol.147
, pp. 370-381
-
-
Sumazin, P.1
-
169
-
-
80054715378
-
A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA
-
Cesana M, et al. A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell 2011;147:358-369.
-
(2011)
Cell
, vol.147
, pp. 358-369
-
-
Cesana, M.1
-
170
-
-
67349123973
-
Redefining microRNA targets
-
Seitz H. Redefining microRNA targets. Curr Biol 2009;19:870-873.
-
(2009)
Curr Biol
, vol.19
, pp. 870-873
-
-
Seitz, H.1
-
171
-
-
34547497309
-
Target mimicry provides a new mechanism for regulation of microRNA activity
-
Franco-Zorrilla JM, et al. Target mimicry provides a new mechanism for regulation of microRNA activity. Nat Genet 2007;39:1033-1037.
-
(2007)
Nat Genet
, vol.39
, pp. 1033-1037
-
-
Franco-Zorrilla, J.M.1
-
172
-
-
46249092601
-
Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites
-
Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB. Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites. Science 2008;320:1643-1647.
-
(2008)
Science
, vol.320
, pp. 1643-1647
-
-
Sandberg, R.1
Neilson, J.R.2
Sarma, A.3
Sharp, P.A.4
Burge, C.B.5
-
173
-
-
34547955952
-
A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway
-
O'Carroll D, et al. A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway. Genes Dev 2007;21:1999-2004.
-
(2007)
Genes Dev
, vol.21
, pp. 1999-2004
-
-
O'Carroll, D.1
-
174
-
-
77956198304
-
Dicer-dependent microRNAs control maturation, function, and maintenance of Langerhans cells in vivo
-
Kuipers H, Schnorfeil F, Fehling H-J, Bartels H, Brocker T. Dicer-dependent microRNAs control maturation, function, and maintenance of Langerhans cells in vivo. J Immunol 2010;185:400-409.
-
(2010)
J Immunol
, vol.185
, pp. 400-409
-
-
Kuipers, H.1
Schnorfeil, F.2
Fehling, H.-J.3
Bartels, H.4
Brocker, T.5
-
175
-
-
67349167059
-
Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay
-
Matsushita K, et al. Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay. Nature 2009;458:1185-1190.
-
(2009)
Nature
, vol.458
, pp. 1185-1190
-
-
Matsushita, K.1
-
176
-
-
36048946330
-
Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA
-
Yu D, et al. Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA. Nature 2007;450:299-303.
-
(2007)
Nature
, vol.450
, pp. 299-303
-
-
Yu, D.1
-
177
-
-
21144438325
-
A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity
-
Vinuesa CG, et al. A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity. Nature 2005;435:452-458.
-
(2005)
Nature
, vol.435
, pp. 452-458
-
-
Vinuesa, C.G.1
-
178
-
-
84855757873
-
The role of Roquin overexpression in the modulation of signaling during in vitro and ex vivo T-cell activation
-
Kim H, et al. The role of Roquin overexpression in the modulation of signaling during in vitro and ex vivo T-cell activation. Biochem Biophys Res Commun 2012;417:280-286.
-
(2012)
Biochem Biophys Res Commun
, vol.417
, pp. 280-286
-
-
Kim, H.1
-
179
-
-
80054842844
-
Loss of Roquin induces early death and immune deregulation but not autoimmunity
-
Bertossi A, et al. Loss of Roquin induces early death and immune deregulation but not autoimmunity. J Exp Med 2011;208:1749-1756.
-
(2011)
J Exp Med
, vol.208
, pp. 1749-1756
-
-
Bertossi, A.1
-
180
-
-
67349227471
-
The p38 MAPK pathway inhibits tristetraprolin-directed decay of interleukin-10 and pro-inflammatory mediator mRNAs in murine macrophages
-
Tudor C, et al. The p38 MAPK pathway inhibits tristetraprolin-directed decay of interleukin-10 and pro-inflammatory mediator mRNAs in murine macrophages. FEBS Lett 2009;583:1933-1938.
-
(2009)
FEBS Lett
, vol.583
, pp. 1933-1938
-
-
Tudor, C.1
-
181
-
-
45249099847
-
Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin
-
Stoecklin G, et al. Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin. J Biol Chem 2008;283:11689-11699.
-
(2008)
J Biol Chem
, vol.283
, pp. 11689-11699
-
-
Stoecklin, G.1
-
182
-
-
33749822544
-
Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling
-
Marderosian M, et al. Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling. Oncogene 2006;25:6277-6290.
-
(2006)
Oncogene
, vol.25
, pp. 6277-6290
-
-
Marderosian, M.1
-
183
-
-
66449118207
-
Tristetraprolin mediates interferon-gamma mRNA decay
-
Ogilvie RL, et al. Tristetraprolin mediates interferon-gamma mRNA decay. J Biol Chem 2009;284:11216-11223.
-
(2009)
J Biol Chem
, vol.284
, pp. 11216-11223
-
-
Ogilvie, R.L.1
-
184
-
-
79958070748
-
Posttranscriptional regulation of IL-23 expression by IFN-gamma through tristetraprolin
-
Qian X, et al. Posttranscriptional regulation of IL-23 expression by IFN-gamma through tristetraprolin. J Immunol 2011;186:6454-6464.
-
(2011)
J Immunol
, vol.186
, pp. 6454-6464
-
-
Qian, X.1
-
185
-
-
77954939922
-
Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia
-
Hodson DJ, et al. Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia. Nat Immunol 2010;11:717-724.
-
(2010)
Nat Immunol
, vol.11
, pp. 717-724
-
-
Hodson, D.J.1
-
186
-
-
67349209595
-
Involvement of Tis11b, an AU-rich binding protein, in induction of apoptosis by rituximab in B cell chronic lymphocytic leukemia cells
-
Baou M, et al. Involvement of Tis11b, an AU-rich binding protein, in induction of apoptosis by rituximab in B cell chronic lymphocytic leukemia cells. Leukemia 2009;23:986-989.
-
(2009)
Leukemia
, vol.23
, pp. 986-989
-
-
Baou, M.1
-
187
-
-
9644295900
-
Destabilization of vascular endothelial growth factor mRNA by the zinc-finger protein TIS11b
-
Ciais D, et al. Destabilization of vascular endothelial growth factor mRNA by the zinc-finger protein TIS11b. Oncogene 2004;23:8673-8680.
-
(2004)
Oncogene
, vol.23
, pp. 8673-8680
-
-
Ciais, D.1
-
188
-
-
70350499492
-
Targeted disruption of Zfp36 l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis
-
Stumpo D, et al. Targeted disruption of Zfp36 l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis. Blood 2009;114:2401-2410.
-
(2009)
Blood
, vol.114
, pp. 2401-2410
-
-
Stumpo, D.1
-
189
-
-
84863842721
-
mRNA decay factor AUF1 maintains normal aging, telomere maintenance, and suppression of senescence by activation of telomerase transcription
-
Pont AR, Sadri N, Hsiao SJ, Smith S, Schneider RJ. mRNA decay factor AUF1 maintains normal aging, telomere maintenance, and suppression of senescence by activation of telomerase transcription. Mol Cell 2012;47:5-15.
-
(2012)
Mol Cell
, vol.47
, pp. 5-15
-
-
Pont, A.R.1
Sadri, N.2
Hsiao, S.J.3
Smith, S.4
Schneider, R.J.5
-
190
-
-
33751257755
-
Endotoxic shock in AUF1 knockout mice mediated by failure to degrade proinflammatory cytokine mRNAs
-
Lu J-Y, Sadri N, Schneider R. Endotoxic shock in AUF1 knockout mice mediated by failure to degrade proinflammatory cytokine mRNAs. Genes Dev 2006;20:3174-3184.
-
(2006)
Genes Dev
, vol.20
, pp. 3174-3184
-
-
Lu, J.-Y.1
Sadri, N.2
Schneider, R.3
-
191
-
-
59949094888
-
Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease
-
Sadri N, Schneider R. Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease. J Invest Dermatol 2009;129:657-670.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 657-670
-
-
Sadri, N.1
Schneider, R.2
-
192
-
-
52049119758
-
AUF1 and HuR proteins stabilize interleukin-8 mRNA in human saliva
-
Palanisamy V, Park N, Wang J, Wong D. AUF1 and HuR proteins stabilize interleukin-8 mRNA in human saliva. J Dental Res 2008;87:772-776.
-
(2008)
J Dental Res
, vol.87
, pp. 772-776
-
-
Palanisamy, V.1
Park, N.2
Wang, J.3
Wong, D.4
-
193
-
-
79960614229
-
p16(INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1
-
Al-Khalaf HH, et al. p16(INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1. PLoS ONE 2011;6:e21111.
-
(2011)
PLoS ONE
, vol.6
-
-
Al-Khalaf, H.H.1
-
194
-
-
3142728532
-
Nucleolin is a second component of the CD154 mRNA stability complex that regulates mRNA turnover in activated T cells
-
Singh K, Laughlin J, Kosinski P, Covey L. Nucleolin is a second component of the CD154 mRNA stability complex that regulates mRNA turnover in activated T cells. J Immunol 2004;173:976-985.
-
(2004)
J Immunol
, vol.173
, pp. 976-985
-
-
Singh, K.1
Laughlin, J.2
Kosinski, P.3
Covey, L.4
-
195
-
-
33947609348
-
Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA
-
Otake Y, et al. Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA. Blood 2007;109:3069-3075.
-
(2007)
Blood
, vol.109
, pp. 3069-3075
-
-
Otake, Y.1
-
196
-
-
0032582696
-
A specific isoform of hnRNP D interacts with DNA in the LR1 heterodimer: canonical RNA binding motifs in a sequence-specific duplex DNA binding protein
-
Dempsey L, Hanakahi L, Maizels N. A specific isoform of hnRNP D interacts with DNA in the LR1 heterodimer: canonical RNA binding motifs in a sequence-specific duplex DNA binding protein. J Biol Chem 1998;273:29224-29229.
-
(1998)
J Biol Chem
, vol.273
, pp. 29224-29229
-
-
Dempsey, L.1
Hanakahi, L.2
Maizels, N.3
-
197
-
-
77955302347
-
HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay
-
Chang N, et al. HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay. Mol Cell Biol 2010;30:3875-3886.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 3875-3886
-
-
Chang, N.1
-
198
-
-
79960929333
-
Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR
-
Lebedeva S, et al. Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR. Mol Cell 2011;43:340-352.
-
(2011)
Mol Cell
, vol.43
, pp. 340-352
-
-
Lebedeva, S.1
-
199
-
-
79960918737
-
Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability
-
Mukherjee N, et al. Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability. Mol Cell 2011;43:327-339.
-
(2011)
Mol Cell
, vol.43
, pp. 327-339
-
-
Mukherjee, N.1
-
200
-
-
67449149662
-
Control of thymic T cell maturation, deletion and egress by the RNA-binding protein HuR
-
Papadaki O, Milatos S, Grammenoudi S, Mukherjee N, Keene J, Kontoyiannis D. Control of thymic T cell maturation, deletion and egress by the RNA-binding protein HuR. J Immunol 2009;182:6779-6788.
-
(2009)
J Immunol
, vol.182
, pp. 6779-6788
-
-
Papadaki, O.1
Milatos, S.2
Grammenoudi, S.3
Mukherjee, N.4
Keene, J.5
Kontoyiannis, D.6
-
201
-
-
34547651351
-
Posttranscriptional orchestration of an anti-apoptotic program by HuR
-
Abdelmohsen K, Lal A, Kim H, Gorospe M. Posttranscriptional orchestration of an anti-apoptotic program by HuR. Cell Cycle 2007;6:1288-1292.
-
(2007)
Cell Cycle
, vol.6
, pp. 1288-1292
-
-
Abdelmohsen, K.1
Lal, A.2
Kim, H.3
Gorospe, M.4
-
202
-
-
34347221942
-
Ott1(Rbm15) has pleiotropic roles in hematopoietic development
-
Raffel G, et al. Ott1(Rbm15) has pleiotropic roles in hematopoietic development. Proc Natl Acad Sci USA 2007;104:6001-6006.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 6001-6006
-
-
Raffel, G.1
-
203
-
-
84861486777
-
Hematopoietic stem cells lacking Ott1 display aspects associated with aging and are unable to maintain quiescence during proliferative stress
-
Xiao N, et al. Hematopoietic stem cells lacking Ott1 display aspects associated with aging and are unable to maintain quiescence during proliferative stress. Blood 2012;119:4898-4907.
-
(2012)
Blood
, vol.119
, pp. 4898-4907
-
-
Xiao, N.1
-
204
-
-
33744465772
-
Activation of the integrated stress response during T helper cell differentiation
-
Scheu S, Stetson D, Reinhardt R, Leber J, Mohrs M, Locksley R. Activation of the integrated stress response during T helper cell differentiation. Nat Immunol 2006;7:644-651.
-
(2006)
Nat Immunol
, vol.7
, pp. 644-651
-
-
Scheu, S.1
Stetson, D.2
Reinhardt, R.3
Leber, J.4
Mohrs, M.5
Locksley, R.6
-
205
-
-
35648933435
-
T-cell intracellular antigen-1 (TIA-1)-induced translational silencing promotes the decay of selected mRNAs
-
Yamasaki S, Stoecklin G, Kedersha N, Simarro M, Anderson P. T-cell intracellular antigen-1 (TIA-1)-induced translational silencing promotes the decay of selected mRNAs. J Biol Chem 2007;282:30070-30077.
-
(2007)
J Biol Chem
, vol.282
, pp. 30070-30077
-
-
Yamasaki, S.1
Stoecklin, G.2
Kedersha, N.3
Simarro, M.4
Anderson, P.5
-
206
-
-
79952253395
-
TIA1 prevents skipping of a critical exon associated with spinal muscular atrophy
-
Singh NN, Seo J, Ottesen EW, Shishimorova M, Bhattacharya D, Singh RN. TIA1 prevents skipping of a critical exon associated with spinal muscular atrophy. Mol Cell Biol 2011;31:935-954.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 935-954
-
-
Singh, N.N.1
Seo, J.2
Ottesen, E.W.3
Shishimorova, M.4
Bhattacharya, D.5
Singh, R.N.6
-
207
-
-
8344259192
-
Human ribosomal protein S3 interacts with DNA base excision repair proteins hAPE/Ref-1 and hOGG1
-
Hegde V, Wang M, Deutsch WA. Human ribosomal protein S3 interacts with DNA base excision repair proteins hAPE/Ref-1 and hOGG1. Biochemistry 2004;43:14211-14217.
-
(2004)
Biochemistry
, vol.43
, pp. 14211-14217
-
-
Hegde, V.1
Wang, M.2
Deutsch, W.A.3
-
208
-
-
77952081927
-
RpS3 translation is repressed by interaction with its own mRNA
-
Kim H, et al. RpS3 translation is repressed by interaction with its own mRNA. J Cell Biochem 2010;110:294-303.
-
(2010)
J Cell Biochem
, vol.110
, pp. 294-303
-
-
Kim, H.1
-
209
-
-
0020790005
-
Crosslinking of eukaryotic initiation factor eIF3 to the 40S ribosomal subunit from rabbit reticulocytes
-
Tolan D, Hershey J, Traut R. Crosslinking of eukaryotic initiation factor eIF3 to the 40S ribosomal subunit from rabbit reticulocytes. Biochimie 1983;65:427-436.
-
(1983)
Biochimie
, vol.65
, pp. 427-436
-
-
Tolan, D.1
Hershey, J.2
Traut, R.3
-
210
-
-
33646173416
-
Multiple domains of EBER 1, an Epstein-Barr virus noncoding RNA, recruit human ribosomal protein L22
-
Fok V, Mitton-Fry RM, Grech A, Steitz JA. Multiple domains of EBER 1, an Epstein-Barr virus noncoding RNA, recruit human ribosomal protein L22. RNA 2006;12:872-882.
-
(2006)
RNA
, vol.12
, pp. 872-882
-
-
Fok, V.1
Mitton-Fry, R.M.2
Grech, A.3
Steitz, J.A.4
-
211
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama M, et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 2004;5:730-737.
-
(2004)
Nat Immunol
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
-
212
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
-
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 2001;413:732-738.
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
213
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
-
Heil F, et al. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 2004;303:1526-1529.
-
(2004)
Science
, vol.303
, pp. 1526-1529
-
-
Heil, F.1
-
214
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 2004;303:1529-1531.
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis, E.S.C.5
-
215
-
-
1842631428
-
Recognition of single-stranded RNA viruses by Toll-like receptor 7
-
Lund JM, et al. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci USA 2004;101:5598-5603.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 5598-5603
-
-
Lund, J.M.1
|