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Volumn 3, Issue 4, 2012, Pages 483-494

A mirror of two faces: Lin28 as a master regulator of both miRNA and mRNA

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN B; CYCLIN DEPENDENT KINASE 4; LIN28 PROTEIN; MESSENGER RNA; MICRORNA; OCTAMER TRANSCRIPTION FACTOR 4; RNA BINDING PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84863806564     PISSN: 17577004     EISSN: 17577012     Source Type: Journal    
DOI: 10.1002/wrna.1112     Document Type: Review
Times cited : (80)

References (71)
  • 1
    • 0021771445 scopus 로고
    • Heterochronic mutants of the nematode Caenorhabditis elegans.
    • Ambros V, Horvitz HR. Heterochronic mutants of the nematode Caenorhabditis elegans. Science 1984, 226:409-416.
    • (1984) Science , vol.226 , pp. 409-416
    • Ambros, V.1    Horvitz, H.R.2
  • 2
    • 0030970775 scopus 로고    scopus 로고
    • The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA.
    • Moss EG, Lee RC, Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell 1997, 88:637-646.
    • (1997) Cell , vol.88 , pp. 637-646
    • Moss, E.G.1    Lee, R.C.2    Ambros, V.3
  • 3
    • 0037783427 scopus 로고    scopus 로고
    • Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites.
    • Moss EG, Tang L. Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites. Dev Biol 2003, 258:432-442.
    • (2003) Dev Biol , vol.258 , pp. 432-442
    • Moss, E.G.1    Tang, L.2
  • 5
    • 62549132535 scopus 로고    scopus 로고
    • Genetic analysis of the role of the reprogramming gene LIN-28 in human embryonic stem cells.
    • Darr H, Benvenisty N. Genetic analysis of the role of the reprogramming gene LIN-28 in human embryonic stem cells. Stem Cells 2009, 27:352-362.
    • (2009) Stem Cells , vol.27 , pp. 352-362
    • Darr, H.1    Benvenisty, N.2
  • 6
    • 0346250854 scopus 로고    scopus 로고
    • The transcriptome profile of human embryonic stem cells as defined by SAGE.
    • Richards M, Tan SP, Tan JH, Chan WK, Bongso A. The transcriptome profile of human embryonic stem cells as defined by SAGE. Stem Cells 2004, 22:51-64.
    • (2004) Stem Cells , vol.22 , pp. 51-64
    • Richards, M.1    Tan, S.P.2    Tan, J.H.3    Chan, W.K.4    Bongso, A.5
  • 7
    • 68749102148 scopus 로고    scopus 로고
    • TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation.
    • Heo I, Joo C, Kim YK, Ha M, Yoon MJ, Cho J, Yeom KH, Han J, Kim VN. TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell 2009, 138:696-708.
    • (2009) Cell , vol.138 , pp. 696-708
    • Heo, I.1    Joo, C.2    Kim, Y.K.3    Ha, M.4    Yoon, M.J.5    Cho, J.6    Yeom, K.H.7    Han, J.8    Kim, V.N.9
  • 8
    • 79953015943 scopus 로고    scopus 로고
    • Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells.
    • Peng S, Chen LL, Lei XX, Yang L, Lin H, Carmichael GG, Huang Y. Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells. Stem Cells 2011, 29:496-504.
    • (2011) Stem Cells , vol.29 , pp. 496-504
    • Peng, S.1    Chen, L.L.2    Lei, X.X.3    Yang, L.4    Lin, H.5    Carmichael, G.G.6    Huang, Y.7
  • 11
    • 33751042873 scopus 로고    scopus 로고
    • Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma.
    • Guo Y, Chen Y, Ito H, Watanabe A, Ge X, Kodama T, Aburatani H. Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma. Gene 2006, 384:51-61.
    • (2006) Gene , vol.384 , pp. 51-61
    • Guo, Y.1    Chen, Y.2    Ito, H.3    Watanabe, A.4    Ge, X.5    Kodama, T.6    Aburatani, H.7
  • 12
    • 67650931988 scopus 로고    scopus 로고
    • Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II.
    • Lu L, Katsaros D, Shaverdashvili K, Qian B, Wu Y, de la Longrais IA, Preti M, Menato G, Yu H. Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II. Eur J Cancer 2009, 45:2212-2218.
    • (2009) Eur J Cancer , vol.45 , pp. 2212-2218
    • Lu, L.1    Katsaros, D.2    Shaverdashvili, K.3    Qian, B.4    Wu, Y.5    de la Longrais, I.A.6    Preti, M.7    Menato, G.8    Yu, H.9
  • 13
    • 77950794030 scopus 로고    scopus 로고
    • Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer.
    • Peng S, Maihle NJ, Huang Y. Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer. Oncogene 2010, 29:2153-2159.
    • (2010) Oncogene , vol.29 , pp. 2153-2159
    • Peng, S.1    Maihle, N.J.2    Huang, Y.3
  • 15
    • 80053585752 scopus 로고    scopus 로고
    • LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms.
    • King CE, Wang L, Winograd R, Madison BB, Mongroo PS, Johnstone CN, Rustgi AK. LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms. Oncogene 2011, 30:4185-4193.
    • (2011) Oncogene , vol.30 , pp. 4185-4193
    • King, C.E.1    Wang, L.2    Winograd, R.3    Madison, B.B.4    Mongroo, P.S.5    Johnstone, C.N.6    Rustgi, A.K.7
  • 17
    • 77957358029 scopus 로고    scopus 로고
    • A Yin-Yang balancing act of the lin28/let-7 link in tumorigenesis.
    • Ji J, Wang XW. A Yin-Yang balancing act of the lin28/let-7 link in tumorigenesis. J Hepatol 2010, 53:974-975.
    • (2010) J Hepatol , vol.53 , pp. 974-975
    • Ji, J.1    Wang, X.W.2
  • 18
    • 78549261109 scopus 로고    scopus 로고
    • Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells.
    • Yang X, Lin X, Zhong X, Kaur S, Li N, Liang S, Lassus H, Wang L, Katsaros D, Montone K, et al. Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells. Cancer Res 2010, 70:9463-9472.
    • (2010) Cancer Res , vol.70 , pp. 9463-9472
    • Yang, X.1    Lin, X.2    Zhong, X.3    Kaur, S.4    Li, N.5    Liang, S.6    Lassus, H.7    Wang, L.8    Katsaros, D.9    Montone, K.10
  • 19
    • 77953032534 scopus 로고    scopus 로고
    • Emerging paradigms of regulated microRNA processing.
    • Newman MA, Hammond SM. Emerging paradigms of regulated microRNA processing. Genes Dev 2010, 24:1086-1092.
    • (2010) Genes Dev , vol.24 , pp. 1086-1092
    • Newman, M.A.1    Hammond, S.M.2
  • 20
    • 77049099101 scopus 로고    scopus 로고
    • Lin28: a microRNA regulator with a macro role.
    • Viswanathan SR, Daley GQ. Lin28: a microRNA regulator with a macro role. Cell 2010, 140:445-449.
    • (2010) Cell , vol.140 , pp. 445-449
    • Viswanathan, S.R.1    Daley, G.Q.2
  • 21
    • 79958279955 scopus 로고    scopus 로고
    • Regulation of pre-miRNA Processing.
    • Lehrbach NJ, Miska EA. Regulation of pre-miRNA Processing. Adv Exp Med Biol 2011, 700:67-75.
    • (2011) Adv Exp Med Biol , vol.700 , pp. 67-75
    • Lehrbach, N.J.1    Miska, E.A.2
  • 22
    • 34447530917 scopus 로고    scopus 로고
    • Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules.
    • Balzer E, Moss EG. Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules. RNA Biol 2007, 4:16-25.
    • (2007) RNA Biol , vol.4 , pp. 16-25
    • Balzer, E.1    Moss, E.G.2
  • 23
    • 48649103982 scopus 로고    scopus 로고
    • A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment.
    • Rybak A, Fuchs H, Smirnova L, Brandt C, Pohl EE, Nitsch R, Wulczyn FG. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol 2008, 10:987-993.
    • (2008) Nat Cell Biol , vol.10 , pp. 987-993
    • Rybak, A.1    Fuchs, H.2    Smirnova, L.3    Brandt, C.4    Pohl, E.E.5    Nitsch, R.6    Wulczyn, F.G.7
  • 24
    • 77950344768 scopus 로고    scopus 로고
    • Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells.
    • Qiu C, Ma Y, Wang J, Peng S, Huang Y. Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells. Nucleic Acids Res 2010, 38:1240-1248.
    • (2010) Nucleic Acids Res , vol.38 , pp. 1240-1248
    • Qiu, C.1    Ma, Y.2    Wang, J.3    Peng, S.4    Huang, Y.5
  • 26
    • 40849108663 scopus 로고    scopus 로고
    • Selective blockade of MicroRNA processing by Lin-28.
    • Viswanathan SR, Daley GQ, Gregory RI. Selective blockade of MicroRNA processing by Lin-28. Science 2008, 320:97-100.
    • (2008) Science , vol.320 , pp. 97-100
    • Viswanathan, S.R.1    Daley, G.Q.2    Gregory, R.I.3
  • 27
    • 47949100595 scopus 로고    scopus 로고
    • Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing.
    • Newman MA, Thomson JM, Hammond SM. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 2008, 14:1539-1549.
    • (2008) RNA , vol.14 , pp. 1539-1549
    • Newman, M.A.1    Thomson, J.M.2    Hammond, S.M.3
  • 28
    • 53949088050 scopus 로고    scopus 로고
    • Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA.
    • Heo I, Joo C, Cho J, Ha M, Han J, Kim VN. Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA. Mol Cell 2008, 32:276-284.
    • (2008) Mol Cell , vol.32 , pp. 276-284
    • Heo, I.1    Joo, C.2    Cho, J.3    Ha, M.4    Han, J.5    Kim, V.N.6
  • 29
  • 35
    • 72549085095 scopus 로고    scopus 로고
    • Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function.
    • Pawlicki JM, Steitz JA. Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function. Trends Cell Biol 2010, 20:52-61.
    • (2010) Trends Cell Biol , vol.20 , pp. 52-61
    • Pawlicki, J.M.1    Steitz, J.A.2
  • 36
    • 70349820140 scopus 로고    scopus 로고
    • Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells.
    • Hagan JP, Piskounova E, Gregory RI. Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells. Nat Struct Mol Biol 2009, 16:1021-1025.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 1021-1025
    • Hagan, J.P.1    Piskounova, E.2    Gregory, R.I.3
  • 40
    • 84855471182 scopus 로고    scopus 로고
    • Importance of the NCp7-like domain in the recognition of pre-let-7g by the pluripotency factor Lin28.
    • Desjardins A, Yang A, Bouvette J, Omichinski JG, Legault P. Importance of the NCp7-like domain in the recognition of pre-let-7g by the pluripotency factor Lin28. Nucleic Acids Res 2011, 40:1767-1777.
    • (2011) Nucleic Acids Res , vol.40 , pp. 1767-1777
    • Desjardins, A.1    Yang, A.2    Bouvette, J.3    Omichinski, J.G.4    Legault, P.5
  • 41
    • 81855228621 scopus 로고    scopus 로고
    • Molecular basis for interaction of let-7 microRNAs with Lin28.
    • Nam Y, Chen C, Gregory RI, Chou JJ, Sliz P. Molecular basis for interaction of let-7 microRNAs with Lin28. Cell 2011, 147:1080-1091.
    • (2011) Cell , vol.147 , pp. 1080-1091
    • Nam, Y.1    Chen, C.2    Gregory, R.I.3    Chou, J.J.4    Sliz, P.5
  • 42
    • 77955425756 scopus 로고    scopus 로고
    • Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis.
    • Michlewski G, Caceres JF. Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Nat Struct Mol Biol 2010, 17:1011-1018.
    • (2010) Nat Struct Mol Biol , vol.17 , pp. 1011-1018
    • Michlewski, G.1    Caceres, J.F.2
  • 43
    • 50549095181 scopus 로고    scopus 로고
    • Let-7 microRNAs in development, stem cells and cancer.
    • Bussing I, Slack FJ, Grosshans H. Let-7 microRNAs in development, stem cells and cancer. Trends Mol Med 2008, 14:400-409.
    • (2008) Trends Mol Med , vol.14 , pp. 400-409
    • Bussing, I.1    Slack, F.J.2    Grosshans, H.3
  • 44
    • 1942494040 scopus 로고    scopus 로고
    • Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation.
    • Sempere LF, Freemantle S, Pitha-Rowe I, Moss E, Dmitrovsky E, Ambros V. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol 2004, 5:R13.
    • (2004) Genome Biol , vol.5
    • Sempere, L.F.1    Freemantle, S.2    Pitha-Rowe, I.3    Moss, E.4    Dmitrovsky, E.5    Ambros, V.6
  • 45
    • 27144475302 scopus 로고    scopus 로고
    • Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells.
    • Wu L, Belasco JG. Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells. Mol Cell Biol 2005, 25:9198-9208.
    • (2005) Mol Cell Biol , vol.25 , pp. 9198-9208
    • Wu, L.1    Belasco, J.G.2
  • 46
    • 79955567590 scopus 로고    scopus 로고
    • Recent progress in the study of the genetics of height.
    • Lettre G. Recent progress in the study of the genetics of height. Hum Genet 2011, 129:465-472.
    • (2011) Hum Genet , vol.129 , pp. 465-472
    • Lettre, G.1
  • 50
    • 0344013522 scopus 로고    scopus 로고
    • Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse.
    • Yang DH, Moss EG. Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse. Gene Expr Patterns 2003, 3:719-726.
    • (2003) Gene Expr Patterns , vol.3 , pp. 719-726
    • Yang, D.H.1    Moss, E.G.2
  • 51
    • 62549160957 scopus 로고    scopus 로고
    • Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation.
    • Zeitels LR, Hwang HW, Chivukula RR, Wentzel EA, Dews M, Jung J, Gao P, Dang CV, Beer MA
    • Chang TC, Zeitels LR, Hwang HW, Chivukula RR, Wentzel EA, Dews M, Jung J, Gao P, Dang CV, Beer MA, et al. Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci U S A 2009, 106:3384-3389.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3384-3389
    • Chang, T.C.1
  • 53
    • 70350778443 scopus 로고    scopus 로고
    • An epigenetic switch involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation.
    • Iliopoulos D, Hirsch HA, Struhl K. An epigenetic switch involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell 2009, 139:693-706.
    • (2009) Cell , vol.139 , pp. 693-706
    • Iliopoulos, D.1    Hirsch, H.A.2    Struhl, K.3
  • 54
    • 52949091534 scopus 로고    scopus 로고
    • The let-7 family of microRNAs.
    • Roush S, Slack FJ. The let-7 family of microRNAs. Trends Cell Biol 2008, 18:505-516.
    • (2008) Trends Cell Biol , vol.18 , pp. 505-516
    • Roush, S.1    Slack, F.J.2
  • 55
    • 34247589770 scopus 로고    scopus 로고
    • Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency.
    • Polesskaya A, Cuvellier S, Naguibneva I, Duquet A, Moss EG, Harel-Bellan A. Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency. Genes Dev 2007, 21:1125-1138.
    • (2007) Genes Dev , vol.21 , pp. 1125-1138
    • Polesskaya, A.1    Cuvellier, S.2    Naguibneva, I.3    Duquet, A.4    Moss, E.G.5    Harel-Bellan, A.6
  • 57
    • 76249119007 scopus 로고    scopus 로고
    • Opposing microRNA families regulate self-renewal in mouse embryonic stem cells.
    • Melton C, Judson RL, Blelloch R. Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. Nature 2010, 463:621-626.
    • (2010) Nature , vol.463 , pp. 621-626
    • Melton, C.1    Judson, R.L.2    Blelloch, R.3
  • 58
    • 78650658030 scopus 로고    scopus 로고
    • Identification of microRNAs regulating reprogramming factor LIN28 in embryonic stem cells and cancer cells.
    • Zhong X, Li N, Liang S, Huang Q, Coukos G, Zhang L. Identification of microRNAs regulating reprogramming factor LIN28 in embryonic stem cells and cancer cells. J Biol Chem 2010, 285:41961-41971.
    • (2010) J Biol Chem , vol.285 , pp. 41961-41971
    • Zhong, X.1    Li, N.2    Liang, S.3    Huang, Q.4    Coukos, G.5    Zhang, L.6
  • 59
    • 77950357078 scopus 로고    scopus 로고
    • LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro.
    • Balzer E, Heine C, Jiang Q, Lee VM, Moss EG. LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro. Development 2010, 137:891-900.
    • (2010) Development , vol.137 , pp. 891-900
    • Balzer, E.1    Heine, C.2    Jiang, Q.3    Lee, V.M.4    Moss, E.G.5
  • 60
    • 60849116964 scopus 로고    scopus 로고
    • Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells.
    • Xu B, Zhang K, Huang Y. Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells. RNA 2009, 15:357-361.
    • (2009) RNA , vol.15 , pp. 357-361
    • Xu, B.1    Zhang, K.2    Huang, Y.3
  • 61
    • 67949115698 scopus 로고    scopus 로고
    • Histone H2a mRNA interacts with Lin28 and contains a Lin28-dependent posttranscriptional regulatory element.
    • Xu B, Huang Y. Histone H2a mRNA interacts with Lin28 and contains a Lin28-dependent posttranscriptional regulatory element. Nucleic Acids Res 2009, 37:4256-4263.
    • (2009) Nucleic Acids Res , vol.37 , pp. 4256-4263
    • Xu, B.1    Huang, Y.2
  • 62
    • 63649126256 scopus 로고    scopus 로고
    • Regulation of pluripotency and reprogramming by transcription factors.
    • Pei D. Regulation of pluripotency and reprogramming by transcription factors. J Biol Chem 2009, 284:3365-3369.
    • (2009) J Biol Chem , vol.284 , pp. 3365-3369
    • Pei, D.1
  • 66
    • 34547211817 scopus 로고    scopus 로고
    • The long unwinding road of RNA helicases.
    • Bleichert F, Baserga SJ. The long unwinding road of RNA helicases. Mol Cell 2007, 27:339-352.
    • (2007) Mol Cell , vol.27 , pp. 339-352
    • Bleichert, F.1    Baserga, S.J.2
  • 67
    • 79960724199 scopus 로고    scopus 로고
    • From unwinding to clamping-the DEAD box RNA helicase family.
    • Linder P, Jankowsky E. From unwinding to clamping-the DEAD box RNA helicase family. Nat Rev Mol Cell Biol 2011, 12:505-516.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 505-516
    • Linder, P.1    Jankowsky, E.2
  • 69
    • 0242268550 scopus 로고    scopus 로고
    • Primary sequence and secondary structure motifs in spleen necrosis virus RU5 confer translational utilization of unspliced human immunodeficiency virus type 1 reporter RNA.
    • Roberts TM, Boris-Lawrie K. Primary sequence and secondary structure motifs in spleen necrosis virus RU5 confer translational utilization of unspliced human immunodeficiency virus type 1 reporter RNA. J Virol 2003, 77:11973-11984.
    • (2003) J Virol , vol.77 , pp. 11973-11984
    • Roberts, T.M.1    Boris-Lawrie, K.2
  • 70
    • 77950493743 scopus 로고    scopus 로고
    • RNA helicase A modulates translation of HIV-1 and infectivity of progeny virions.
    • Bolinger C, Sharma A, Singh D, Yu L, Boris-Lawrie K. RNA helicase A modulates translation of HIV-1 and infectivity of progeny virions. Nucleic Acids Res 2010, 38:1686-1696.
    • (2010) Nucleic Acids Res , vol.38 , pp. 1686-1696
    • Bolinger, C.1    Sharma, A.2    Singh, D.3    Yu, L.4    Boris-Lawrie, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.