NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

Genes and Development

Volumn 22, Issue 10, 2008, Pages 1381-1396

  Weischenfeldt, Joachim ^a,b   Damgaard, Inge ^a,b   Bryder, David ^c   Theilgaard Mönch, Kim ^a,b   Thoren, Lina A ^d   Nielsen, Finn Cilius ^a   Jacobsen, Sten Eirik W ^d   Nerlov, Claus ^d,e   Porse, Bo Torben ^a,b  

^a Mental Health Services CPH   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c LUND UNIVERSITY   (Sweden)

^d LUND UNIVERSITY   (Sweden)

^e EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL   (Italy)

Author keywords

Alternative splicing; Hematopoietic stem and progenitor cells; Nonsense mediated mRNA decay; Programmed DNA rearrangements; Pseudogenes; T cell development

Indexed keywords

DNA; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE DELETION; GENE EXPRESSION; GENE LOCUS; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PSEUDOGENE; STEM CELL; T LYMPHOCYTE RECEPTOR GENE; UPF2 GENE;

ANIMALS; BASE SEQUENCE; CARRIER PROTEINS; CELLS, CULTURED; CODON, NONSENSE; GENE EXPRESSION PROFILING; GENE REARRANGEMENT; HEMATOPOIETIC STEM CELLS; HUMANS; LYMPHOID PROGENITOR CELLS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, BIOLOGICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA STABILITY; SEQUENCE DELETION;

MAMMALIA; MUS;

EID: 44149104364     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.468808     Document Type: Article

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