KSRP promotes the maturation of a group of miRNA precuresors

Advances in Experimental Medicine and Biology

Volumn 700, Issue , 2010, Pages 36-42

  Trabucchi, Michele ^a   Briata, Paola ^b   Filipowicz, Witold ^b   Ramos, Andres ^b   Gherzi, Roberto ^b   Rosenfeld, Michael G ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DEAD BOX PROTEIN; DEAD BOX RNA HELICASE 17 PROTEIN; DICER; DROSHA PROTEIN; ESTROGEN RECEPTOR ALPHA; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; KH TYPE SPLICING REGULATORY PROTEIN; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P68; REGULATOR PROTEIN; RIBONUCLEASE; SINGLE STRANDED RNA; UNCLASSIFIED DRUG; COREPRESSOR PROTEIN; KHSRP PROTEIN, HUMAN; RNA BINDING PROTEIN; RNA PRECURSOR; TRANSACTIVATOR PROTEIN; MESSENGER RNA;

ARTICLE; CELL PROLIFERATION; GENE CONTROL; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC ASSOCIATION; HUMAN; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN RNA BINDING; RNA PROCESSING; RNA SEQUENCE; SIGNAL TRANSDUCTION; ANIMAL; CELL DIFFERENTIATION; NEOPLASM; PHYSIOLOGY; GENE EXPRESSION; GENETICS;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CO-REPRESSOR PROTEINS; HUMANS; MICRORNAS; NEOPLASMS; RNA PRECURSORS; RNA-BINDING PROTEINS; TRANS-ACTIVATORS; GENE EXPRESSION; GENE EXPRESSION REGULATION; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER;

EID: 79958279101     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-7823-3_4     Document Type: Article

References (45)

1. Davis BN, Hata A. Regulation of microRNA Biogenesis: A miRiad of mechanisms. Cell Commun Signal 2009; 7(1):18
2. Winter J, Jung S, Keller S et al. Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat Cell Biol 2009; 11(3):228-234
3. Morlando M, Ballarino M, Gromak N et al. Primary microRNA transcripts are processed cotranscriptionally. Nat Struct Mol Biol 2008; 15(9):902-909
4. Ballarino M, Pagano F, Girardi E et al. Coupled RNA processing and transcription of intergenic primary microRNAs. Mol Cell Biol 2009; 29(20):5632-5638
5. Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 2008; 9(2):102-114
6. Liu X, Fortin K, Mourelatos Z. microRNAs: biogenesis and molecular functions. Brain Pathol 2008; 18(1):113-121
7. Schmittgen TD. Regulation of microRNA processing in development, differentiation and cancer. J Cell Mol Med 2008; 12(5B):1811-1819
8. Davis BN, Hilyard AC, Lagna G et al. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008; 454(7200):56-61 (Pubitemid 351931982)
9. Fukuda T, Yamagata K, Fujiyama S et al. DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol 2007; 9(5):604-611 (Pubitemid 46696543)
10. Guil S, Caceres JF. The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a. Nat Struct Mol Biol 2007; 14(7):591-596 (Pubitemid 47037061)
11. Obernosterer G, Leuschner PJ, Alenius M et al. Post-transcriptional regulation of microRNA expression. Rna 2006; 12(7):1161-1167 (Pubitemid 43990541)
12. Trabucchi M, Briata P, Garcia-Mayoral M et al. The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature 2009; 459(7249):1010-1014
13. Viswanathan SR, Daley GQ, Gregory RI. Selective blockade of microRNA processing by Lin28. Science 2008; 320(5872):97-100 (Pubitemid 351490762)
14. Suzuki HI, Yamagata K, Sugimoto K et al. Modulation of microRNA processing by p53. Nature 2009; 460(7254):529-533
15. Yamagata K, Fujiyama S, Ito S et al. Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell 2009; 36(2):340-347
16. Chen CY, Gherzi R, Ong SE et al. AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. Cell 2001; 107(4):451-464 (Pubitemid 33152781)
17. Garcia-Mayoral MF, Hollingworth D, Masino L et al. The structure of the C-terminal KH domains of KSRP reveals a noncanonical motif important for mRNA degradation. Structure 2007; 15(4):485-498 (Pubitemid 46551731)
18. Gherzi R, Lee KY, Briata P et al. A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery. Mol Cell 2004; 14(5):571-583 (Pubitemid 38739081)
19. Kroll TT, Zhao WM, Jiang C et al. A homolog of FBP2/KSRP binds to localized mRNAs in Xenopus oocytes. Development 2002; 129(24):5609-5619 (Pubitemid 36054606)
20. Min H, Turck CW, Nikolic JM et al. A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer. Genes Dev 1997; 11(8):1023-1036 (Pubitemid 27199881)
21. Ruggiero T, Trabucchi M, De Santa F et al. LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. Faseb J 2009; 23(9):2898-2908
22. Michlewski G, Guil S, Semple CA et al. Post-transcriptional regulation of miRNAs harboring conserved terminal loops. Mol Cell 2008; 32(3):383-393
23. Ruggiero T, Trabucchi M, Ponassi M et al. Identification of a set of KSRP target transcripts upregulated by PI3K-AKT signaling. BMC Mol Biol 2007; 8:28
24. Garcia-Mayoral MF, Diaz-Moreno I, Hollingworth D et al. The sequence selectivity of KSRP explains its flexibility in the recognition of the RNA targets. Nucleic Acids Res 2008
25. Newman MA, Thomson JM, Hammond SM. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. Rna 2008; 14(8):1539-1549
26. Piskounova E, Viswanathan SR, Janas M et al. Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J Biol Chem 2008; 283(31):21310-21314
27. Rybak A, Fuchs H, Smirnova L et al. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol 2008; 10(8):987-993
28. Wulczyn FG, Smirnova L, Rybak A et al. Post-transcriptional regulation of the let-7 microRNA during neural cell specification. Faseb J 2007; 21(2):415-426 (Pubitemid 46213489)
29. Hagan JP, Piskounova E, Gregory RI. Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells. Nat Struct Mol Biol 2009; 16(10):1021-1025
30. Heo I, Joo C, Kim YK et al. TUT4 in concert with Lin28 suppresses microRNA biogenesis through Pre-microRNA uridylation. Cell 2009; 138(4):696-708
31. Lehrbach NJ, Armisen J, Lightfoot HL et al. LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans. Nat Struct Mol Biol 2009; 16(10):1016-1020
32. Sakamoto S, Aoki K, Higuchi T et al. The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway. Mol Cell Biol 2009; 29(13):3754-3769
33. Chen JF, Mandel EM, Thomson JM et al. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 2006; 38(2):228-233 (Pubitemid 43177239)
34. KimHK, Lee YS, SivaprasadUetal. Muscle-specific microRNAmiR-206 promotes muscle differentiation. J Cell Biol 2006; 174(5):677-687
35. Allemand E, Guil S, Myers M et al. Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock. Proc Natl Acad Sci USA 2005; 102(10):3605-3610 (Pubitemid 40354658)
36. Shimada N, Rios I, Moran H et al. p38 MAP kinase-dependent regulation of the expression level and subcellular distribution of heterogeneous nuclear ribonucleoprotein A1 and its involvement in cellular senescence in normal human fibroblasts. RNA Biol 2009; 6(3)
37. Briata P, Forcales SV, Ponassi M et al. p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts. Mol Cell 2005; 20(6):891-903 (Pubitemid 41814878)
38. Diaz-Moreno I, Hollingworth D, Frenkiel TA et al. Phosphorylation- mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding. Nat Struct Mol Biol 2009; 16(3):238-246
39. Gherzi R, Trabucchi M, Ponassi M et al. The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling. PLoS Biol 2006; 5(1):e5
40. Thomson JM, Newman M, Parker JS et al. Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev 2006; 20(16):2202-2207
41. Lu J, Getz G, Miska EA et al. microRNA expression profiles classify human cancers. Nature 2005; 435(7043):834-838 (Pubitemid 40839735)
42. Kumar MS, Lu J, Mercer KL. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet 2007; 39(5):673-677 (Pubitemid 46676103)
43. Guo J, Li ZC, Feng YH. Expression and activation of the reprogramming transcription factors. Biochem Biophys Res Commun 2009; 390(4):1081-1086
44. Heo I, Joo C, Cho J et al. Lin28 mediates the terminal uridylation of let-7 precursor microRNA. Mol Cell 2008; 32(2):276-284
45. Bussing I, Slack FJ, Grosshans H. let-7 microRNAs in development, stem cells and cancer. Trends Mol Med 2008; 14(9):400-409