Endotoxic shock in AUF1 knockout mice mediated by failure to degrade proinflammatory cytokine mRNAs

Genes and Development

Volumn 20, Issue 22, 2006, Pages 3174-3184

  Lu, Jin Yu ^a,b   Sadri, Navid ^a   Schneider, Robert J ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ARE; AU rich element; AUF1; Cytokines; Endotoxic shock; mRNA decay

Indexed keywords

CYTOKINE; ENDOTOXIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; BLOOD CLOTTING; CELL POPULATION; CONTROLLED STUDY; DNA HYBRIDIZATION; ENDOTOXEMIA; INFLAMMATION; MACROPHAGE; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEPTIC SHOCK;

ANIMALS; GENE EXPRESSION REGULATION; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN D; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; KIDNEY; LIPOPOLYSACCHARIDES; LIVER; LUNG; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; MORTALITY; RNA STABILITY; RNA, MESSENGER; SHOCK, SEPTIC; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS);

EID: 33751257755     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1467606     Document Type: Article

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