Salmonella control in live pigs and at slaughter

Veterinary Journal

Volumn 196, Issue 1, 2013, Pages 20-27

  De Busser, Emily V ^a   De Zutter, Lieven ^a   Dewulf, Jeroen ^a   Houf, Kurt ^a   Maes, Dominiek ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Control; Pig; Primary production; Salmonella; Slaughterhouse

Indexed keywords

CARBOXYLIC ACID; DRINKING WATER; SALMONELLOSIS VACCINE;

ACID TOLERANCE; ANIMAL FOOD; ANIMAL HOUSING; ANIMAL SALMONELLOSIS; ANTIBODY RESPONSE; BACTERIAL COLONIZATION; BACTERIAL SHEDDING; BACTERIAL TRANSMISSION; BACTERIUM CONTAMINATION; BIOFILM; CLEANING; CROSS PROTECTION; DISINFECTION; FOOD COMPOSITION; FOOD CONTAMINATION; FOOD SAFETY; HYGIENE; INFECTION CONTROL; NONHUMAN; PIG FARMING; REVIEW; SALMONELLA TYPHIMURIUM; SEROPREVALENCE; SLAUGHTERHOUSE; SWINE; TRANSPORT STRESS; VACCINATION;

ABATTOIRS; ANIMAL HUSBANDRY; ANIMALS; EUROPEAN UNION; FOOD HANDLING; FOOD MICROBIOLOGY; MEAT; SALMONELLA; SALMONELLA INFECTIONS, ANIMAL; SWINE; SWINE DISEASES; TRANSPORTATION;

PROTOZOA; SALMONELLA; SUIDAE;

EID: 84875608801     PISSN: 10900233     EISSN: 15322971     Source Type: Journal    
DOI: 10.1016/j.tvjl.2013.01.002     Document Type: Review

References (122)

1. Alban L., Stärk K.D.C. Where should the effort be put to reduce the Salmonella prevalence in the slaughtered swine carcass effectively?. Preventive Veterinary Medicine 2005, 68:63-79.
2. Anonymous, 2010. Circular Letter Concerning the Control of Salmonella in Animal Feed. Federal Agency for the Safety of the Food Chain, Belgium, June 2010.
3. Arts J.H., Rennen M.A., de Heer C. Inhaled formaldehyde: Evaluation of sensory irritation in relation to carcinogenicity. Regulatory Toxicology and Pharmacology 2006, 44:144-160.
4. Baptista, F.M., 2010b. Salmonella in pigs and pork in Denmark and Portugal. Use of risk-based principles to achieve cost-effective surveillance strategies. PhD thesis, Faculty of Life Sciences, University of Copenhagen, Denmark.
5. Baptista F.M., Dahl J., Nielsen L.R. Factors influencing Salmonella carcass prevalence in Danish pig abattoirs. Preventive Veterinary Medicine 2010, 95:231-238.
6. Barton Gade P., Blaabjerg L., Christensen L. New lairage system for slaughter pigs-effect on behavior and quality characteristics. Meat Focus International 1993, 2:115-118.
7. Bearson B.L., Wilson L., Foster J.W. A low pH-inducible, PhoPQ-dependent acid tolerance response protects Salmonella Typhimurium against inorganic acid stress. Journal of Bacteriology 1998, 180:2409-2417.
8. Berends B.R., Urlings H.A.P., Snijders J.M.A., Knapen F.V. Identification and quantification of risk factors in animal management and transport regarding Salmonella spp. in pigs. International Journal of Food Microbiology 1996, 30:37-53.
9. Berends B.R., Van Knapen F., Snijders J.M., Mossel D.A. Identification and quantification of risk factors regarding Salmonella spp. on pork carcasses. International Journal of Food Microbiology 1997, 36:199-206.
10. Bertrand S., Dierick K., Heylen K., De Baere T., Pochet B., Robesyn E., Lokietek S., Van Meervenne E., Imberechts H., De Zutter L., Collard J.M. Lessons learned from the management of a national outbreak of Salmonella Ohio linked to pork meat processing and distribution. Journal of Food Protection 2010, 73:529-534.
11. Bode, K., Baier, S., Blaha, T., 2007. Specific cleaning and disinfection procedures for Salmonella infected pig herds. In: Proceedings of the 13th International Congress in Animal Hygiene (ISAH), Tartu, Estonia, pp. 500-506.
12. Bollaerts K., Messens W., Aerts M., Dewulf J., Maes D., Grijspeerdt K., Van der Stede Y. Evaluation of scenarios for reducing human salmonellosis through household consumption of fresh minced pork meat. Risk Analysis 2010, 30:853-865.
13. Borch E., Nesbakken T., Christensen H. Hazard identification in swine slaughter with respect to foodborne bacteria. International Journal of Food Microbiology 1996, 30:9-25.
14. Botteldoorn N., Heyndrickx M., Rijpens N., Grijspeerdt K., Herman L. Salmonella on pig carcasses: Positive pigs and cross contamination in the slaughterhouse. Journal of Applied Microbiology 2003, 95:891-903.
15. Boyen F., Haesebrouck F., Vanparys A., Volf J., Mahu M., Van Immerseel F., Rychlik I., Dewulf J., Ducatelle R., Pasmans F. Coated fatty acids alter virulence properties of Salmonella Typhimurium and decrease intestinal colonization of pigs. Veterinary Microbiology 2008, 132:319-327.
16. Bradshaw R.H., Parrott R.F., Goode J.A., Lloyd D.M., Rodway R.G., Broom D.M. Behavioural and hormonal responses of pigs during transport: Effect of mixing and duration of journey. Journal of Animal Science 1996, 62:547-554.
17. Brandl M.T., Rosenthal B.M., Haxo A.F., Berk S.G. Enhanced survival of Salmonella enterica in vesicles released by a soilborne Tetrahymena species. Applied and Environmental Microbiology 2005, 71:1562-1569.
18. Canibe N., Hojberg O., Hojsgaard S., Jensen B.B. Feed physical form and formic acid addition to feed affect the gastrointestinal ecology and growth performance of growing pigs. Journal of Animal Science 2005, 83:1287-1302.
19. Carrique-Mas J.J., Bedford S., Davies R.H. Organic acid and formaldehyde treatment of animal feeds to control Salmonella: Efficacy and masking during culture. Journal of Applied Microbiology 2006, 103:88-96.
20. Childers A.B., Keahey E.E. Reduction of Salmonella and faecal contamination of pork during swine slaughter. Journal of the American Veterinary Medical Association 1977, 171:1161-1164.
21. Cortinas Abrahantes J., Bollaerts K., Aerts M., Ogunsanya V., Van der Stede Y. Salmonella serosurveillance: Different statistical methods to categorize pig herds based on serological data. Preventive Veterinary Medicine 2009, 89:59-66.
22. Creus E., Pérez J.F., Peralta B., Baucells F., Mateu E. Effect of acidified feed on the prevalence of Salmonella in market-age pigs. Zoonoses and Public Health 2007, 54:314-319.
23. Davies R., Breslin M. Effects of vaccination and other preventive methods for Salmonella Enteritidis on commercial laying chicken farms. Veterinary Record 2003, 153:673-677.
24. Davies R.H., Hinton M.H. Salmonella in animal feed. Salmonella in Domestic Animals 2000, 285-300. CABI Publishing, Oxon. C. Wray, A. Wray (Eds.).
25. Davies P.R., Funk J., Morgan M. Faecal shedding of Salmonella by gilts before and after introduction to a swine breeding farm. Swine Health Production 2000, 8:25-29.
26. De Busser E.V., Dewulf J., Nollet N., Houf K., Schwarzer K., De Sadeleer L., De Zutter L., Maes D. Effect of organic acids in drinking water during the last 2 weeks prior to slaughter on Salmonella shedding by slaughter pigs and contamination of carcasses. Zoonoses and Public Health 2009, 56:129-136.
27. De Busser E.V., Maes D., Houf K., Dewulf J., Imberechts H., Bertrand S., De Zutter L. Detection and characterization of Salmonella in lairage, on pig carcasses and intestines in five slaughterhouses. International Journal of Food Microbiology 2011, 145:279-286.
28. De Ridder, L., Maes, D., Dewulf, J., Pasmans, F., Boyen, F., Méroc, E., Butaye, P., Van der Stede, Y., 2011. Transmission study of Salmonella in pigs with 3 intervention strategies. In: Proceedings of the 9th International Conference on the Epidemiology and Control of Biological, Chemical and Physical Hazards in Pigs and Pork, Safepork Congress, Maastricht, The Netherlands, pp. 30-33.
29. De Sadeleer L., Dewulf J., De Zutter L., Van der Stede Y., Ribbens S., De Busser E., Quoilin S., Houf K., Delhalle L., Grijspeerdt K., Maes D. A qualitative risk assessment for human salmonellosis due to the consumption of fresh pork in Belgium. Vlaams Diergeneeskundig Tijdschrift 2008, 78:34-43.
30. Delhalle L., De Sadeleer L., Bollaerts K., Farnir F., Saegerman C., Korsak N., Dewulf J., De Zutter L., Daube G. Risk factors for Salmonella and hygiene indicators in the 10 largest Belgian pig slaughterhouses. Journal of Food Protection 2008, 71:1320-1329.
31. Dougan G., John V., Palmer S., Mastroeni P. Immunity to salmonellosis. Immunological Reviews 2011, 240:196-210.
32. Duggan S.J., Mannion C., Prendergast D.M., Leonard N., Fanning S., Gonzales-Barron U., Egan J., Butler F., Duffy G. Tracking the Salmonella status of pigs and pork from lairage through slaughter process in the Republic of Ireland. Journal of Food Protection 2010, 73:2148-2160.
33. Eddicks M., Palzer A., Hormansdorfer S., Ritzmann M., Heinritzi K. Examination of the compatibility of a Salmonella Typhimurium-live vaccine Salmoporc® for three day old suckling piglets. Deutsche Tierärztliche Wochenschrift 2009, 116:249-254.
34. EFSA Report of the task force on zoonoses data collection on the analysis of the baseline survey on the prevalence of Salmonella in slaughter pigs, Part A. The EFSA Journal 2008, 135:1-111.
35. EFSA Scientific opinion of the Panel on Biological Hazards on a request from the Health and Consumer Protection, Directorate General, European Commission on Microbiological Risk Assessment in feeding stuffs for food producing animals. The EFSA Journal 2008, 720:1-84.
36. EFSA Analysis of the baseline survey on the prevalence of Salmonella in holdings with breeding pigs in the EU, 2008. Part A: Salmonella prevalence estimates. The EFSA Journal 2009, 7:1377.
37. EFSA Scientific opinion on a quantitative microbiological risk assessment of Salmonella in slaughter and breeder pigs. The EFSA Journal 2010, 8:1547.
38. EFSA Analysis of the baseline survey on the prevalence of Salmonella in holdings with breeding pigs in the EU, 2008. Part B: Factors associated with Salmonella pen positivity. The EFSA Journal 2011, 9:2329.
39. EFSA The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2010. The EFSA Journal 2012, 10:2597.
40. Ekperigin H.E., Nagaraja K.V. Microbial food borne pathogens. Salmonella. Veterinary Clinics of North America, Food Animal Practice 1998, 14:17-29.
41. Farzan A., Friendship R.M., Dewey C.E., Warriner K., Poppe C., Klotins K. Prevalence of Salmonella spp. on Canadian pig farms using liquid or dry feeding. Preventive Veterinary Medicine 2006, 73:241-254.
42. Fedorka-Cray P.J., Whipp S.C., Isaacson R.E., Nord N., Lager K. Transmission of Salmonella Typhimurium to swine. Veterinary Microbiology 1994, 41:333-344.
43. Fedorka-Cray P.J., Harris D.L., Whipp S.C. Using isolated weaning to raise Salmonella free swine. Veterinary Medicine 1997, 92:375-382.
44. Fosse J., Seegers H., Magras C. Prevalence and risk factors for bacterial food-borne zoonotic hazards in slaughter pigs: A review. Zoonoses and Public Health 2009, 56:29-54.
45. Funk J.A., Davies P.R., Nichols M.A. Longitudinal study of Salmonella enterica in growing pigs reared in multiple-site swine production systems. Veterinary Microbiology 2001, 83:45-60.
46. Gil-Cruz C., Bobat S., Marshall J.L., Kingsley R.A., Ross E.A., Henderson I.R., Leyton D.L., Coughlan R.E., Khan M., Jensen K.T., Buckley C.D., Dougan G., MacLennan I.C., López-Macías C., Cunningham A.F. The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response. Proceedings of the National Academy of Sciences of the USA 2009, 106:9803-9980.
47. Goldbach S.G., Alban L. A cost-benefit analysis of Salmonella control strategies in Danish pork production. Preventive Veterinary Medicine 2006, 77:1-14.
48. Griffith R.W., Schwartz K.J., Meyerholz D.K. Salmonella. Diseases of Swine 2006, 739-751. Blackwell Publishing, (Chapter 45). Ninth Ed. B.E. Straw, J.J. Zimmerman, S. D'Allaire, D.J. Taylor (Eds.).
49. Guan T.Y., Holley R.A. Pathogen survival in swine manure environments and transmission of human enteric illness - A review. Journal of Environmental Quality 2003, 32:383-392.
50. Guàrdia M.D., Gispert M., Diestre A. Mortality rates during transport and lairage in pigs for slaughter. Meat Focus International 1996, 10:362-366.
51. Guàrdia M.D., Estany J., Balash S., Oliver M.A., Gispert M., Diestre A. Risk assessment of PSE condition due to pre-slaughter conditions and RYR1 gene in pigs. Meat Science 2004, 67:471-478.
52. Guàrdia M.D., Estany J., Balash S., Oliver M.A., Gispert M., Diestre A. Risk assessment of DFD condition due to pre-slaughter conditions and RYR1 gene in pigs. Meat Science 2005, 70:709-716.
53. Haesebrouck F., Pasmans F., Chiers K., Maes D., Ducatelle R., Decostere A. Efficacy of vaccines against bacterial diseases in swine: What can we expect?. Veterinary Microbiology 2004, 100:255-268.
54. Häggblom, P., 2009. The Feed Borne Outbreak of Salmonella Tennessee in Finland in the Spring of 2009. National Veterinary Institute (SVA), p. 20. (accessed 13 April 2012). http://www.mmm.fi/attachments/mmm/tiedotteet/5mlkunEwY.
55. Hald T., Wingstrand A., Swanenburg M., von Altrock A., Thorberg B.M. The occurrence and epidemiology of Salmonella in European pig slaughterhouses. Epidemiology and Infection 2003, 131:1187-1203.
56. Hamilton D., Holds G., Lorimer M., Kiermeier A., Kidd C., Slade J., Pointon A. Slaughterfloor decontamination of pork carcasses with hot water or acidified sodium chlorite - A comparison in two Australian abattoirs. Zoonoses and Public Health 2010, 57:16-22.
57. Hendriksen S.W.M., Orsel K., Wagenaar J.A., Miko A., van Duijkeren E. Animal-to-human transmission of Salmonella Typhimurium DT104A variant. Emerging Infectious Diseases 2004, 10:2225-2227.
58. Hill, A., Simons, R., Swart, A., Kelly, L., Hald, T., Snary, E., 2011. A farm transmission model for Salmonella in pigs for individual EU Member States. In: Proceedings of the 9th International Conference on the Epidemiology and Control of Biological, Chemical and Physical Hazards in Pigs and Pork, Safepork Congress, Maastricht, The Netherlands, p. 29.
59. Himathongkham S., Gracas Pereira M.D., Riemann H. Heat destruction of Salmonella in poultry feed: Effect of time, temperature, and moisture. Avian Diseases 1996, 40:72-77.
60. Hotes S., Traulsen I., Krieter J. Salmonella control measures with special focus on vaccination and logistic slaughter procedures. Transboundary and Emerging Diseases 2011, 58:434-444.
61. Hurd H.S., McKean J.D., Wesley I.V., Karriker L.A. The effect of lairage on Salmonella isolation from market swine. Journal of Food Protection 2001, 64:939-944.
62. Iba A.M., Berchieri A. Studies on the use of a formic acid-propionic acid mixture (bio-add) to control experimental Salmonella infection in broiler chickens. Avian Pathology 1995, 24:303-311.
63. ISO (International Organization for Standardization), 2007. Detection of Salmonella spp. in Animal Faeces and in Environmental Samples from the Primary Production Stage, ISO 6579:2002/Amd 1:2007, Annex D.
64. Jensen, T., Christensen, H., 2000. Decontamination of Pork, Documentation of the Effect through Investigations in the Abattoir. Work No. 18.361, Report of 23th of August, Danish Meat Research Institute, pp. 3-5.
65. Jones F.T. A review of practical Salmonella control measures in animal feed. Journal of Applied Poultry Research 2011, 20:102-113.
66. Jones F.T., Richardson K.E. Salmonella in commercially manufactured feeds. Poultry Science 2004, 83:384-391.
67. King C.H., Shotts E.B., Wooley R.E., Porter K.G. Survival of coliforms and bacterial pathogens within protozoa during chlorination. Applied Environmental Microbiology 1988, 54:3023-3033.
68. Kong Q., Yang J., Liu Q., Alamuri P., Roland K.L., Curtiss R. Effect of deletion of genes involved in lipopolysaccharide core and O-antigen synthesis on virulence and immunogenicity of Salmonella enterica serovar Typhimurium. Infection and Immunity 2011, 79:4227-4239.
69. Kranker S., Alban L., Boes J., Dahl J. Longitudinal study of Salmonella enterica serotype Typhimurium infection in three Danish farrow-to-finish swine herds. Journal of Clinical Microbiology 2003, 41:2282-2288.
70. Lammens V., Peeters E., De Maere H., De Mey E., Pealinck H., Leyten J., Geers R. A survey of pork quality in relation to pre-slaughter conditions, slaughterhouse facilities and quality assurance. Meat Science 2007, 75:381-387.
71. Lawson L.G., Jensen J.D., Christiansen P., Lund M. Cost-effectiveness of Salmonella reduction in Danish abattoirs. International Journal of Food Microbiology 2009, 134:126-132.
72. Leyman, B., 2012. Optimizing vaccination of pigs against Salmonella Typhimurium. PhD Thesis, Faculty of Veterinary Medicine, University of Ghent, Belgium.
73. Leyman B., Boyen F., Van Parys A., Verbrugghe E., Haesebrouck F., Pasmans F. Salmonella Typhimurium LPS mutations for use in vaccines allowing differentiation of infected and vaccinated pigs. Vaccine 2011, 29:3679-3685.
74. Lindner, T., Springer, S. Selbitz, H.J., 2007. The use of a Salmonella Typhimurium live vaccine to control Salmonella Typhimurium in fattening pigs in field and effects on serological surveillance. In: Proceedings of the 7th International Symposium on the Epidemiology and Control of Foodborne Pathogens in Pork, Safepork, Verona, Italy, pp. 237-239.
75. Lo Fo Wong, D.M.A., Hald, T., 2000. Salmonella in pork (SALINPORK): Pre-harvest and Harvest Control Options based on Epidemiological, Diagnostic and Economic Research. Final Report, Contract No: FAIR1 CT95-0400, pp. 18-24.
76. Lo Fo Wong D.M.A., Hald T., van der Wolf P.J., Swanenburg M. Epidemiology and control measures for Salmonella in pigs and pork. Livestock Production Science 2002, 76:215-222.
77. Lo Fo Wong D.M.A., Dahl J., Stege H., Van Der Wolf P.J., Leontides L., Von Altrock A., Thorberg B.M. Herd-level risk factors for subclinical Salmonella infection in European finishing pig herds. Preventive Veterinary Medicine 2004, 62:253-266.
78. Mannion C., Lynch P.B., Egan J., Leonard F.C. Efficacy of cleaning and disinfection on pig farms in Ireland. Veterinary Record 2007, 161:371-375.
79. Marin C., Hernandiz A., Lainez M. Biofilm development capacity of Salmonella strains isolated in poultry risk factors and their resistance against disinfectants. Poultry Science 2009, 88:424-431.
80. Martín-Peláez S., Peralta B., Creus E., Dalmau A., Velarde A., Pérez J.F., Mateu E., Martín-Orúe S.M. Different feed withdrawal times before slaughter influence caecal fermentation and faecal Salmonella shedding in pigs. The Veterinary Journal 2009, 182:469-473.
81. Mastroeni P., Chabalgoity J.A., Dunstan S.J., Maskell D.J., Dougan G. Salmonella immune responses and vaccines. The Veterinary Journal 2000, 161:132-164.
82. McLaren I., Wales A., Breslin M., Davies R. Evaluation of commonly used farm disinfectants in wet and dry models of Salmonella farm contamination. Avian Pathology 2011, 40:33-42.
83. Mikkelsen L.L., Naughton P.J., Hedemann M.S., Jensen B.B. Effects of physical properties of feed on microbial ecology and survival of Salmonella enterica serovar Typhimurium in the pig gastrointestinal tract. Applied and Environmental Microbiology 2004, 70:3485-3492.
84. Nagy G., Pál T. Lipopolysaccharide: A tool and target in enterobacterial vaccine development. Biological Chemistry 2008, 389:513-520.
85. Nagy G., Palkovics T., Otto A., Kusch H., Kocsis B., Dobrindt U., Engelmans S., Hecker M., Emody L., Hacker J. 'Gently rough': The vaccine potential of a Salmonella enterica regulatory lipopolysaccharide mutant. The Journal of Infectious Diseases 2008, 198:1699-1706.
86. Nanni Costa L., Lo Fiego D.P., Dall'olio S., Davoli R., Russo V. Combined effects of pre-slaughter treatments and lairage time on carcass and meat quality in pigs of different halothane genotype. Meat Science 2002, 61:41-47.
87. Nielsen B., Baggesen D., Bager F., Haugegaard J., Lind P. The serological response to Salmonella serovars Typhimurium and Infantis in experimentally infected pigs. The time course followed with an indirect anti-LPS ELISA and bacteriological examination. Veterinary Microbiology 1995, 47:205-218.
88. Peisker, M., 2006. Feed processing - Impacts on nutritive value and hygienic status in broiler feeds. In: Proceedings of the 18th Australian Poultry Science Symposium, Sydney, New South Wales, Australia, pp. 7-16.
89. Poljak Z., Dewey C.E., Friendship R.M., Martin S.W., Christensen J. Multilevel analysis of risk factors for Salmonella shedding in Ontario finishing pigs. Epidemiology and Infection 2008, 136:1388-1400.
90. Quessy, S., Guevremont, E., Beauchamp, G., D'Allaire, S., Fournaise, S., Poppe, C., Sanderson, T., Letellier, A., 2005. Risk factors associated with presence of Salmonella in pigs in Canada. In: Proceedings of the 6th International Symposium on the Epidemiology and Control of Foodborne Pathogens in pork, CALIFORNIA, USA, pp. 16-18.
91. Ricke S.C. Ensuring the safety of poultry feed. Food Safety Control in the Poultry Industry 2005, 174-194. Woodhead Publishing Ltd., Cambridge, UK,. G.C. MEAD (Ed.).
92. Rossel R., Jouffe L., Beloeil P.A. Analyse des facteurs associés à la contamination des carcasses de porcs par Salmonella à l'aide des réseaux bayésiens. Journées de la Recherche Porcine 2009, 41:43-48.
93. Rostagno M.H., Eicher S.D., Lay D.C. Does pre-slaughter stress affect pork safety risk?. Journal of Animal Science 2011, 89:430.
94. Santiviago C.A., Toro C.S., Hidalgo A.A., Youderian P., Mora G.C. Global regulation of the Salmonella enterica serovar Typhimurium major porin, OmpD. Journal of Bacteriology 2003, 185:5901-5905.
95. Saucier L., Bernier D., Bergeron R., Méthot S., Giguère A., Faucitano L. Effect of feed texture, meal frequency and pre-slaughter fasting on behaviour, stomach weight and microbial carcass contamination in pigs. Canadian Journal of Animal Science 2007, 87:479-486.
96. Sauli I., Danuser J., Geeraerd A.H., Van Impe J.F., Rüfenacht J., Bissig-Choisat B., Wenk C., Stärk K.D. Estimating the probability and level of contamination with Salmonella of feed for finishing pigs produced in Switzerland - The impact of the production pathway. International Journal of Food Microbiology 2005, 100:289-310.
97. Schütte A., Mergens A., Pott S., Venthien S. Effect of different kinds of showering in lairage on physiological and meat quality parameters, taking climate circumstances into account. Landbauforschung Völkenrode Sonderheft 1996, 166:181-201.
98. Schwarz P., Kich J.D., Kolb J., Cardoso M. Use of an avirulent live Salmonella Cholerasuis vaccine to reduce the prevalence of Salmonella carrier pigs at slaughter. Veterinary Record 2011, 169:553.
99. Selke, M., 2006. Development of a DIVA vaccine against Salmonella Typhimurium infection. Thesis, Submitted in Partial Fulfilment of the Requirements for the Degree of Philosophical Doctor, Hannover, Germany.
100. Selke M., Meens J., Springer S., Frank R., Gerlach G.F. Immunization of pigs to prevent disease in humans: Construction and protective efficacy of a Salmonella enterica serovar Typhimurium live negative-marker vaccine. Infection and Immunity 2007, 75:2476-2483.
101. Smid J.H., Heres L., Havelaar A.H., Pielaat A. A biotracing model of Salmonella in the pork production chain. Journal of Food Protection 2012, 75:270-280.
102. Sörqvist S., Danielsson-Tham M.L. Survival of Campylobacter, Salmonella and Yersinia spp. in scalding water used at pig slaughter. Fleischwirtsch 1990, 70:1451-1454.
103. Swanenburg M., Berend B.R., Urlings H.A.P., Snijders J.M.A., van Knapen F. Epidemiological investigations into the sources of Salmonella contamination of pork. Berliner und Münchener Tierärztliche Wochenschrift 2001, 114:356-359.
104. Swanenburg M., Urlings H.A.P., Keuzenkamp D.A., Snijders J.M.A. Salmonella in the lairage of pig slaughterhouses. Journal of Food Protection 2001, 64:12-16.
105. Swanenburg M., Urlings H.A.P., Snijders J.M.A., Keuzenkamp D.A., van Knapen F. Salmonella in slaughter pigs: Prevalence, serotypes and critical control points during slaughter in two slaughterhouses. International Journal of Food Microbiology 2001, 70:247-258.
106. Taylor J., McCoy J.N. Salmonella and Arizona infections. Foodborne Infections and Intoxications 1969, 3-72. Academic Press, New York, USA. H. Riemann (Ed.).
107. Tezcan-Merdol D., Ljungström M., Winiecka-Krusnell J., Linder E., Engstrand L., Rhen M. Uptake and replication of Salmonella enterica in Acanthamoeba rhysodes. Applied and Environmental Microbiology 2004, 70:3706-3714.
108. van der Gaag M.A., Vos F., Saatkamp H.W., van Boven M., van Beek P., Huirne R.B.M. A state-transmission simulation model for the spread of Salmonella in the pork supply chain. European Journal of Operational Research 2004, 156:782-798.
109. van der Heijden, M., van Dam, H., Niewerth, D., Frankena, K., 2005. Effectiveness of Salmonella control strategies in fattening pigs. In: Proceedings of the 6th International Symposium on the Epidemiology and Control of Foodborne Pathogens in Pork, California, USA, pp. 145-148.
110. Van der Wolf P.J., Wolbers W.B., Elbers A.R., van der Heijden H.M., Koppen J.M., Hunneman W.A., van Schie F.W., Tielen M.J. Herd level husbandry factors associated with the serological Salmonella prevalence in finishing pig herds in The Netherlands. Veterinary Microbiology 2001, 78:205-219.
111. Van der Wolf P.J., van Schie F.W., Elbers A.R., Engel B., van der Heijden H.M., Hunneman W.A., Tielen M.J. Administration of acidified drinking water to finishing pigs in order to prevent Salmonella infections. Veterinary Quarterly 2001, 23:121-125.
112. Veldman A., Vahl H.A., Borggreve G.J., Fuller D.C. A survey of the incidence of Salmonella species and Enterobacteriaceae in poultry feeds and feed components. Veterinary Record 1995, 136:169-172.
113. Vieira-Pinto M., Tenreiro R., Martines C. Unveiling contamination sources and dissemination routes of Salmonella spp. in pigs at a Portuguese slaughterhouse through macrorestriction profiling by pulsed-field gel electrophoresis. International Journal of Food Microbiology 2006, 110:77-84.
114. Wales A.D., McLaren I.M., Bedford S., Carrique-Mas J.J., Cook A.J.C., Davies R.H. Longitudinal survey of the occurrence of Salmonella in pigs and the environment of nucleus breeder and multiplier pig herds in England. Veterinary Record 2009, 165:648-657.
115. Wales A.D., Allen V.M., Davies R.H. Chemical treatment of animal feed and water for the control of Salmonella. Foodborne Pathogens and Disease 2010, 7:3-15.
116. Wallis T.S. Salmonella pathogenesis and immunity: We need affective multivalent vaccines. The Veterinary Journal 2001, 161:104-106.
117. Warriss P.D. Guidelines for the handling of pigs ante-mortem. Meat Focus International 1996, 4:89-92.
118. Warriss P.D., Brown S.N., Edwards J.E., Anil M.H., Fordham D.P. Time in lairage needed by pigs to recover from the stress of transport. Veterinary Record 1992, 131:194-196.
119. Warriss P.D., Brown S.N., Edwards J.E., Knowles T.G. Effect of lairage time on levels of stress and meat quality in pigs. Animal Science 1998, 66:255-261.
120. Wonderling L., Pearce R., Morgan Wallace F., Call J.E., Feder I., Tamplin M., Luchansky J.B. Use of pulsed-field gel electrophoresis to characterize the heterogeneity and clonality of Salmonella isolates obtained from the carcasses and faeces of swine at slaughter. Applied and Environmental Microbiology 2003, 69:4177-4182.
121. Xu H.R., Hsu H.S., Moncure C.W., King R.A. Correlation of antibody titers induced by vaccination with protection in mouse typhoid. Vaccine 1993, 11:725-729.
122. Yamane Y., Leonard J.D., Kobatake R., Awamura N., Toyota Y., Ohta H., Otsuki K., Inove T. A case study of Salmonella enteritidis origin at three egg laying farms and its control with a Salmonella enterica bacterin. Avian Disease 2000, 44:519-526.