-
1
-
-
33847718707
-
Dynamic control of signaling by modular adaptor proteins
-
Pawson T.Dynamic control of signaling by modular adaptor proteins.Curr Opin Cell Biol. 2007;19:112-6.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 112-116
-
-
Pawson, T.1
-
2
-
-
70849112486
-
Cell signaling in space and time: where proteins come together and when they're apart
-
Scott JD,Pawson T.Cell signaling in space and time: where proteins come together and when they're apart.Science. 2009;326:1220-4.
-
(2009)
Science
, vol.326
, pp. 1220-1224
-
-
Scott, J.D.1
Pawson, T.2
-
3
-
-
0029666251
-
p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase
-
Harte MT,Hildebrand JD,Burnham MR,Bouton AH,Parsons JT.p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase.J Biol Chem. 1996;271:13649-55.
-
(1996)
J Biol Chem
, vol.271
, pp. 13649-13655
-
-
Harte, M.T.1
Hildebrand, J.D.2
Burnham, M.R.3
Bouton, A.H.4
Parsons, J.T.5
-
4
-
-
33751335857
-
Force sensing by mechanical extension of the Src family kinase substrate p130Cas
-
Sawada Y,Tamada M,Dubin-Thaler BJ, et al.Force sensing by mechanical extension of the Src family kinase substrate p130Cas.Cell. 2006;127:1015-26.
-
(2006)
Cell
, vol.127
, pp. 1015-1026
-
-
Sawada, Y.1
Tamada, M.2
Dubin-Thaler, B.J.3
-
5
-
-
7744232293
-
Activation of a signaling cascade by cytoskeleton stretch
-
Tamada M,Sheetz MP,Sawada Y.Activation of a signaling cascade by cytoskeleton stretch.Dev Cell. 2004;7:709-18.
-
(2004)
Dev Cell
, vol.7
, pp. 709-718
-
-
Tamada, M.1
Sheetz, M.P.2
Sawada, Y.3
-
6
-
-
0032559562
-
CAS/Crk coupling serves as a "molecular switch" for induction of cell migration
-
Klemke RL,Leng J,Molander R,Brooks PC,Vuori K,Cheresh DA.CAS/Crk coupling serves as a "molecular switch" for induction of cell migration.J Cell Biol. 1998;140:961-72.
-
(1998)
J Cell Biol
, vol.140
, pp. 961-972
-
-
Klemke, R.L.1
Leng, J.2
Molander, R.3
Brooks, P.C.4
Vuori, K.5
Cheresh, D.A.6
-
7
-
-
0035475308
-
Crk family adaptors-signalling complex formation and biological roles
-
Feller SM.Crk family adaptors-signalling complex formation and biological roles.Oncogene. 2001;20:6348-71.
-
(2001)
Oncogene
, vol.20
, pp. 6348-6371
-
-
Feller, S.M.1
-
8
-
-
3042717667
-
Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold
-
Chodniewicz D,Klemke RL.Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold.Biochim Biophys Acta. 2004;1692:63-76.
-
(2004)
Biochim Biophys Acta
, vol.1692
, pp. 63-76
-
-
Chodniewicz, D.1
Klemke, R.L.2
-
9
-
-
0033605279
-
Cell adhesion regulates the interaction between the docking protein p130(Cas) and the 14-3-3 proteins
-
Garcia-Guzman M,Dolfi F,Russello M,Vuori K.Cell adhesion regulates the interaction between the docking protein p130(Cas) and the 14-3-3 proteins.J Biol Chem. 1999;274:5762-8.
-
(1999)
J Biol Chem
, vol.274
, pp. 5762-5768
-
-
Garcia-Guzman, M.1
Dolfi, F.2
Russello, M.3
Vuori, K.4
-
10
-
-
20444506822
-
The serine-rich domain from Crk-associated substrate (p130cas) is a four-helix bundle
-
Briknarova K,Nasertorabi F,Havert ML, et al.The serine-rich domain from Crk-associated substrate (p130cas) is a four-helix bundle.J Biol Chem. 2005;280:21908-14.
-
(2005)
J Biol Chem
, vol.280
, pp. 21908-21914
-
-
Briknarova, K.1
Nasertorabi, F.2
Havert, M.L.3
-
13
-
-
82955167894
-
NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling
-
Mace PD,Wallez Y,Dobaczewska MK, et al.NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling.Nat Struct Mol Biol. 2011;18:1381-7.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 1381-1387
-
-
Mace, P.D.1
Wallez, Y.2
Dobaczewska, M.K.3
-
14
-
-
3142723481
-
Atrophin-1-interacting protein 4/human Itch is a ubiquitin E3 ligase for human enhancer of filamentation 1 in transforming growth factor-beta signaling pathways
-
Feng L,Guedes S,Wang T.Atrophin-1-interacting protein 4/human Itch is a ubiquitin E3 ligase for human enhancer of filamentation 1 in transforming growth factor-beta signaling pathways.J Biol Chem. 2004;279:29681-90.
-
(2004)
J Biol Chem
, vol.279
, pp. 29681-29690
-
-
Feng, L.1
Guedes, S.2
Wang, T.3
-
15
-
-
10444279104
-
Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1
-
Nourry C,Maksumova L,Pang M,Liu X,Wang T.Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1.BMC Cell Biol. 2004;5:20.
-
(2004)
BMC Cell Biol
, vol.5
, pp. 20
-
-
Nourry, C.1
Maksumova, L.2
Pang, M.3
Liu, X.4
Wang, T.5
-
16
-
-
34548357152
-
Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle
-
Singh M,Cowell L,Seo S,O'Neill G,Golemis E.Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle.Cell Biochem Biophys. 2007;48:54-72.
-
(2007)
Cell Biochem Biophys
, vol.48
, pp. 54-72
-
-
Singh, M.1
Cowell, L.2
Seo, S.3
O'Neill, G.4
Golemis, E.5
-
17
-
-
35148825060
-
A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9
-
O'Neill GM,Seo S,Serebriiskii IG,Lessin SR,Golemis EA.A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9.Cancer Res. 2007;67:8975-9.
-
(2007)
Cancer Res
, vol.67
, pp. 8975-8979
-
-
O'Neill, G.M.1
Seo, S.2
Serebriiskii, I.G.3
Lessin, S.R.4
Golemis, E.A.5
-
18
-
-
0029766101
-
Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin
-
Alexandropoulos K,Baltimore D.Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin.Genes Dev. 1996;10:1341-55.
-
(1996)
Genes Dev
, vol.10
, pp. 1341-1355
-
-
Alexandropoulos, K.1
Baltimore, D.2
-
19
-
-
0033860096
-
Regulation of c-SRC activity and function by the adapter protein CAS
-
Burnham MR,Bruce-Staskal PJ,Harte MT, et al.Regulation of c-SRC activity and function by the adapter protein CAS.Mol Cell Biol. 2000;20:5865-78.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5865-5878
-
-
Burnham, M.R.1
Bruce-Staskal, P.J.2
Harte, M.T.3
-
20
-
-
31144437397
-
Molecular basis for regulation of Src by the docking protein p130Cas
-
Nasertorabi F,Tars K,Becherer K, et al.Molecular basis for regulation of Src by the docking protein p130Cas.J Mol Recognit. 2006;19:30-8.
-
(2006)
J Mol Recognit
, vol.19
, pp. 30-38
-
-
Nasertorabi, F.1
Tars, K.2
Becherer, K.3
-
21
-
-
77449105626
-
BCAR3 regulates Src/p130 Cas association, Src kinase activity, and breast cancer adhesion signaling
-
Schuh NR,Guerrero MS,Schrecengost RS,Bouton AH.BCAR3 regulates Src/p130 Cas association, Src kinase activity, and breast cancer adhesion signaling.J Biol Chem. 2010;285:2309-17.
-
(2010)
J Biol Chem
, vol.285
, pp. 2309-2317
-
-
Schuh, N.R.1
Guerrero, M.S.2
Schrecengost, R.S.3
Bouton, A.H.4
-
22
-
-
0030585376
-
Src kinase plays an essential role in integrin-mediated tyrosine phosphorylation of Crk-associated substrate p130Cas
-
Hamasaki K,Mimura T,Morino N, et al.Src kinase plays an essential role in integrin-mediated tyrosine phosphorylation of Crk-associated substrate p130Cas.Biochem Biophys Res Commun. 1996;222:338-43.
-
(1996)
Biochem Biophys Res Commun
, vol.222
, pp. 338-343
-
-
Hamasaki, K.1
Mimura, T.2
Morino, N.3
-
23
-
-
0034769929
-
Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src
-
Ruest PJ,Shin NY,Polte TR,Zhang X,Hanks SK.Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src.Mol Cell Biol. 2001;21:7641-52.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7641-7652
-
-
Ruest, P.J.1
Shin, N.Y.2
Polte, T.R.3
Zhang, X.4
Hanks, S.K.5
-
24
-
-
0029664531
-
Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases
-
Vuori K,Hirai H,Aizawa S,Ruoslahti E.Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases.Mol Cell Biol. 1996;16:2606-13.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2606-2613
-
-
Vuori, K.1
Hirai, H.2
Aizawa, S.3
Ruoslahti, E.4
-
25
-
-
0032544426
-
Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex
-
Kiyokawa E,Hashimoto Y,Kurata T,Sugimura H,Matsuda M.Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex.J Biol Chem. 1998;273:24479-84.
-
(1998)
J Biol Chem
, vol.273
, pp. 24479-24484
-
-
Kiyokawa, E.1
Hashimoto, Y.2
Kurata, T.3
Sugimura, H.4
Matsuda, M.5
-
26
-
-
0032513128
-
T cell receptor-mediated tyrosine phosphorylation of Cas-L, a 105-kDa Crk-associated substrate-related protein, and its association of Crk and C3G
-
Ohashi Y,Tachibana K,Kamiguchi K,Fujita H,Morimoto C.T cell receptor-mediated tyrosine phosphorylation of Cas-L, a 105-kDa Crk-associated substrate-related protein, and its association of Crk and C3G.J Biol Chem. 1998;273:6446-51.
-
(1998)
J Biol Chem
, vol.273
, pp. 6446-6451
-
-
Ohashi, Y.1
Tachibana, K.2
Kamiguchi, K.3
Fujita, H.4
Morimoto, C.5
-
27
-
-
5044238876
-
Integrin signalling during tumour progression
-
Guo W,Giancotti FG.Integrin signalling during tumour progression.Nat Rev Mol Cell Biol. 2004;5:816-26.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 816-826
-
-
Guo, W.1
Giancotti, F.G.2
-
30
-
-
0032416722
-
The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway
-
Dolfi F,Garcia-Guzman M,Ojaniemi M,Nakamura H,Matsuda M,Vuori K.The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway.Proc Natl Acad Sci U S A. 1998;95:15394-9.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15394-15399
-
-
Dolfi, F.1
Garcia-Guzman, M.2
Ojaniemi, M.3
Nakamura, H.4
Matsuda, M.5
Vuori, K.6
-
31
-
-
79960113049
-
Signalling to actin: role of C3G, a multitasking guanine-nucleotide-exchange factor
-
Radha V,Mitra A,Dayma K,Sasikumar K.Signalling to actin: role of C3G, a multitasking guanine-nucleotide-exchange factor.Biosci Rep. 2011;31:231-44.
-
(2011)
Biosci Rep
, vol.31
, pp. 231-244
-
-
Radha, V.1
Mitra, A.2
Dayma, K.3
Sasikumar, K.4
-
32
-
-
0032213110
-
Activation of Rac1 by a Crk SH3-binding protein, DOCK180
-
Kiyokawa E,Hashimoto Y,Kobayashi S,Sugimura H,Kurata T,Matsuda M.Activation of Rac1 by a Crk SH3-binding protein, DOCK180.Genes Dev. 1998;12:3331-6.
-
(1998)
Genes Dev
, vol.12
, pp. 3331-3336
-
-
Kiyokawa, E.1
Hashimoto, Y.2
Kobayashi, S.3
Sugimura, H.4
Kurata, T.5
Matsuda, M.6
-
33
-
-
0037115488
-
Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity
-
Cote JF,Vuori K.Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.J Cell Sci. 2002;115:4901-13.
-
(2002)
J Cell Sci
, vol.115
, pp. 4901-4913
-
-
Cote, J.F.1
Vuori, K.2
-
34
-
-
0038495741
-
JNK phosphorylates paxillin and regulates cell migration
-
Huang C,Rajfur Z,Borchers C,Schaller MD,Jacobson K.JNK phosphorylates paxillin and regulates cell migration.Nature. 2003;424:219-23.
-
(2003)
Nature
, vol.424
, pp. 219-223
-
-
Huang, C.1
Rajfur, Z.2
Borchers, C.3
Schaller, M.D.4
Jacobson, K.5
-
35
-
-
4644305806
-
Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration
-
Shin NY,Dise RS,Schneider-Mergener J,Ritchie MD,Kilkenny DM,Hanks SK.Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration.J Biol Chem. 2004;279:38331-7.
-
(2004)
J Biol Chem
, vol.279
, pp. 38331-38337
-
-
Shin, N.Y.1
Dise, R.S.2
Schneider-Mergener, J.3
Ritchie, M.D.4
Kilkenny, D.M.5
Hanks, S.K.6
-
36
-
-
15044359236
-
Linking Rap to cell adhesion
-
Bos JL.Linking Rap to cell adhesion.Curr Opin Cell Biol. 2005;17:123-8.
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 123-128
-
-
Bos, J.L.1
-
37
-
-
33646422461
-
p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis
-
Cabodi S,Tinnirello A,Di Stefano P, et al.p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.Cancer Res. 2006;66:4672-80.
-
(2006)
Cancer Res
, vol.66
, pp. 4672-4680
-
-
Cabodi, S.1
Tinnirello, A.2
Di Stefano, P.3
-
38
-
-
0034194714
-
Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase
-
Almeida EA,Ilic D,Han Q, et al.Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase.J Cell Biol. 2000;149:741-54.
-
(2000)
J Cell Biol
, vol.149
, pp. 741-754
-
-
Almeida, E.A.1
Ilic, D.2
Han, Q.3
-
39
-
-
84860292363
-
p130Cas substrate domain signaling promotes migration, invasion, and survival of estrogen receptor-negative breast cancer cells
-
Cunningham-Edmondson AC,Hanks SK.p130Cas substrate domain signaling promotes migration, invasion, and survival of estrogen receptor-negative breast cancer cells.Breast Cancer. 2009;2009:39-52.
-
(2009)
Breast Cancer
, vol.2009
, pp. 39-52
-
-
Cunningham-Edmondson, A.C.1
Hanks, S.K.2
-
40
-
-
0024427921
-
Stable association of activated pp60src with two tyrosine-phosphorylated cellular proteins
-
Reynolds AB,Kanner SB,Wang HC,Parsons JT.Stable association of activated pp60src with two tyrosine-phosphorylated cellular proteins.Mol Cell Biol. 1989;9:3951-8.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 3951-3958
-
-
Reynolds, A.B.1
Kanner, S.B.2
Wang, H.C.3
Parsons, J.T.4
-
41
-
-
0025877229
-
The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110
-
Kanner SB,Reynolds AB,Wang HC,Vines RR,Parsons JT.The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110.EMBO J. 1991;10:1689-98.
-
(1991)
EMBO J
, vol.10
, pp. 1689-1698
-
-
Kanner, S.B.1
Reynolds, A.B.2
Wang, H.C.3
Vines, R.R.4
Parsons, J.T.5
-
42
-
-
0025298967
-
Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins
-
Matsuda M,Mayer BJ,Fukui Y,Hanafusa H.Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins.Science. 1990;248:1537-9.
-
(1990)
Science
, vol.248
, pp. 1537-1539
-
-
Matsuda, M.1
Mayer, B.J.2
Fukui, Y.3
Hanafusa, H.4
-
43
-
-
17344362766
-
Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas
-
Honda H,Oda H,Nakamoto T, et al.Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas.Nat Genet. 1998;19:361-5.
-
(1998)
Nat Genet
, vol.19
, pp. 361-365
-
-
Honda, H.1
Oda, H.2
Nakamoto, T.3
-
44
-
-
21344443681
-
Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells
-
Brabek J,Constancio SS,Siesser PF,Shin NY,Pozzi A,Hanks SK.Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells.Mol Cancer Res. 2005;3:307-15.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 307-315
-
-
Brabek, J.1
Constancio, S.S.2
Siesser, P.F.3
Shin, N.Y.4
Pozzi, A.5
Hanks, S.K.6
-
45
-
-
77957835305
-
p130Cas is an essential transducer element in ErbB2 transformation
-
Cabodi S,Tinnirello A,Bisaro B, et al.p130Cas is an essential transducer element in ErbB2 transformation.FASEB J. 2010;24:3796-808.
-
(2010)
FASEB J
, vol.24
, pp. 3796-3808
-
-
Cabodi, S.1
Tinnirello, A.2
Bisaro, B.3
-
46
-
-
28444462500
-
p130Cas mediates the transforming properties of the anaplastic lymphoma kinase
-
Ambrogio C,Voena C,Manazza AD, et al.p130Cas mediates the transforming properties of the anaplastic lymphoma kinase.Blood. 2005;106:3907-16.
-
(2005)
Blood
, vol.106
, pp. 3907-3916
-
-
Ambrogio, C.1
Voena, C.2
Manazza, A.D.3
-
47
-
-
61749094852
-
Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling
-
Pylayeva Y,Gillen KM,Gerald W,Beggs HE,Reichardt LF,Giancotti FG.Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling.J Clin Invest. 2009;119:252-66.
-
(2009)
J Clin Invest
, vol.119
, pp. 252-266
-
-
Pylayeva, Y.1
Gillen, K.M.2
Gerald, W.3
Beggs, H.E.4
Reichardt, L.F.5
Giancotti, F.G.6
-
48
-
-
71749099201
-
p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity
-
Wendt MK,Smith JA,Schiemann WP.p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity.J Biol Chem. 2009;284:34145-56.
-
(2009)
J Biol Chem
, vol.284
, pp. 34145-34156
-
-
Wendt, M.K.1
Smith, J.A.2
Schiemann, W.P.3
-
49
-
-
0027185314
-
Induction of antiestrogen resistance in human breast cancer cells by random insertional mutagenesis using defective retroviruses: identification of bcar-1, a common integration site
-
Dorssers LC,van Agthoven T,Dekker A,van Agthoven TL,Kok EM.Induction of antiestrogen resistance in human breast cancer cells by random insertional mutagenesis using defective retroviruses: identification of bcar-1, a common integration site.Mol Endocrinol. 1993;7:870-8.
-
(1993)
Mol Endocrinol
, vol.7
, pp. 870-878
-
-
Dorssers, L.C.1
van Agthoven, T.2
Dekker, A.3
van Agthoven, T.L.4
Kok, E.M.5
-
50
-
-
0034684997
-
BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells
-
Brinkman A,van der Flier S,Kok EM,Dorssers LC.BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells.J Natl Cancer Inst. 2000;92:112-20.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 112-120
-
-
Brinkman, A.1
van der Flier, S.2
Kok, E.M.3
Dorssers, L.C.4
-
51
-
-
58849122389
-
Functional identification of genes causing estrogen independence of human breast cancer cells
-
van Agthoven T,Veldscholte J,Smid M, et al.Functional identification of genes causing estrogen independence of human breast cancer cells.Breast Cancer Res Treat. 2009;114:23-30.
-
(2009)
Breast Cancer Res Treat
, vol.114
, pp. 23-30
-
-
van Agthoven, T.1
Veldscholte, J.2
Smid, M.3
-
52
-
-
55349085753
-
A novel association between p130Cas and resistance to the chemotherapeutic drug adriamycin in human breast cancer cells
-
Ta HQ,Thomas KS,Schrecengost RS,Bouton AH.A novel association between p130Cas and resistance to the chemotherapeutic drug adriamycin in human breast cancer cells.Cancer Res. 2008;68:8796-804.
-
(2008)
Cancer Res
, vol.68
, pp. 8796-8804
-
-
Ta, H.Q.1
Thomas, K.S.2
Schrecengost, R.S.3
Bouton, A.H.4
-
53
-
-
0034684987
-
Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment
-
van der Flier S,Brinkman A,Look MP, et al.Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment.J Natl Cancer Inst. 2000;92:120-7.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 120-127
-
-
van der Flier, S.1
Brinkman, A.2
Look, M.P.3
-
54
-
-
4644285487
-
The prognostic value of BCAR1 in patients with primary breast cancer
-
Dorssers LC,Grebenchtchikov N,Brinkman A, et al.The prognostic value of BCAR1 in patients with primary breast cancer.Clin Cancer Res. 2004;10:6194-202.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6194-6202
-
-
Dorssers, L.C.1
Grebenchtchikov, N.2
Brinkman, A.3
-
55
-
-
77950690680
-
The substrate domain of BCAR1 is essential for anti-estrogen-resistant proliferation of human breast cancer cells
-
Brinkman A,de Jong D,Tuinman S,Azaouagh N,van Agthoven T,Dorssers LC.The substrate domain of BCAR1 is essential for anti-estrogen-resistant proliferation of human breast cancer cells.Breast Cancer Res Treat. 2010;120:401-8.
-
(2010)
Breast Cancer Res Treat
, vol.120
, pp. 401-408
-
-
Brinkman, A.1
de Jong, D.2
Tuinman, S.3
Azaouagh, N.4
van Agthoven, T.5
Dorssers, L.C.6
-
56
-
-
66149098794
-
Expression of a phosphorylated p130(Cas) substrate domain attenuates the phosphatidylinositol 3-kinase/Akt survival pathway in tamoxifen resistant breast cancer cells
-
Soni S,Lin BT,August A,Nicholson RI,Kirsch KH.Expression of a phosphorylated p130(Cas) substrate domain attenuates the phosphatidylinositol 3-kinase/Akt survival pathway in tamoxifen resistant breast cancer cells.J Cell Biochem. 2009;107:364-75.
-
(2009)
J Cell Biochem
, vol.107
, pp. 364-375
-
-
Soni, S.1
Lin, B.T.2
August, A.3
Nicholson, R.I.4
Kirsch, K.H.5
-
57
-
-
16044366598
-
p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene
-
Salgia R,Pisick E,Sattler M, et al.p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene.J Biol Chem. 1996;271:25198-203.
-
(1996)
J Biol Chem
, vol.271
, pp. 25198-25203
-
-
Salgia, R.1
Pisick, E.2
Sattler, M.3
-
58
-
-
0033258545
-
Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas
-
Eisenmann KM,McCarthy JB,Simpson MA, et al.Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas.Nat Cell Biol. 1999;1:507-13.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 507-513
-
-
Eisenmann, K.M.1
McCarthy, J.B.2
Simpson, M.A.3
-
59
-
-
53249107550
-
Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway
-
Frankel P,Pellet-Many C,Lehtolainen P, et al.Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway.EMBO Rep. 2008;9:983-9.
-
(2008)
EMBO Rep
, vol.9
, pp. 983-989
-
-
Frankel, P.1
Pellet-Many, C.2
Lehtolainen, P.3
-
60
-
-
23344448598
-
Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells
-
Hamamura K,Furukawa K,Hayashi T, et al.Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.Proc Natl Acad Sci U S A. 2005;102:11041-6.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 11041-11046
-
-
Hamamura, K.1
Furukawa, K.2
Hayashi, T.3
-
61
-
-
84055191095
-
Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRalpha-stimulated glioma tumorigenesis in mice and humans
-
Feng H,Hu B,Liu KW, et al.Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRalpha-stimulated glioma tumorigenesis in mice and humans.J Clin Invest. 2011;121:4670-84.
-
(2011)
J Clin Invest
, vol.121
, pp. 4670-4684
-
-
Feng, H.1
Hu, B.2
Liu, K.W.3
-
62
-
-
80655144781
-
Silencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell death
-
Nick AM,Stone RL,Armaiz-Pena G, et al.Silencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell death.J Natl Cancer Inst. 2011;103:1596-612.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 1596-1612
-
-
Nick, A.M.1
Stone, R.L.2
Armaiz-Pena, G.3
-
63
-
-
79952030465
-
The integrin signalling adaptor p130CAS is also a key player in prostate cancer
-
Fromont G,Cussenot O.The integrin signalling adaptor p130CAS is also a key player in prostate cancer.Nat Rev Cancer. 2011;11:227.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 227
-
-
Fromont, G.1
Cussenot, O.2
-
64
-
-
33745288277
-
Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene
-
Kim M,Gans JD,Nogueira C, et al.Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene.Cell. 2006;125:1269-81.
-
(2006)
Cell
, vol.125
, pp. 1269-1281
-
-
Kim, M.1
Gans, J.D.2
Nogueira, C.3
-
65
-
-
33751207396
-
Structure and function of cas-L and integrin-mediated signaling
-
Seo S,Ichikawa M,Kurokawa M.Structure and function of cas-L and integrin-mediated signaling.Crit Rev Immunol. 2006;26:391-406.
-
(2006)
Crit Rev Immunol
, vol.26
, pp. 391-406
-
-
Seo, S.1
Ichikawa, M.2
Kurokawa, M.3
-
66
-
-
84861882390
-
The metastasis gene NEDD9 product acts through integrin beta3 and Src to promote mesenchymal motility and inhibit amoeboid motility
-
Ahn J,Sanz-Moreno V,Marshall CJ.The metastasis gene NEDD9 product acts through integrin beta3 and Src to promote mesenchymal motility and inhibit amoeboid motility.J Cell Sci. 2012;125:1814-26.
-
(2012)
J Cell Sci
, vol.125
, pp. 1814-1826
-
-
Ahn, J.1
Sanz-Moreno, V.2
Marshall, C.J.3
-
67
-
-
33645022769
-
HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells
-
Natarajan M,Stewart JE,Golemis EA, et al.HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells.Oncogene. 2006;25:1721-32.
-
(2006)
Oncogene
, vol.25
, pp. 1721-1732
-
-
Natarajan, M.1
Stewart, J.E.2
Golemis, E.A.3
-
68
-
-
34547926839
-
LKB1 modulates lung cancer differentiation and metastasis
-
Ji H,Ramsey MR,Hayes DN, et al.LKB1 modulates lung cancer differentiation and metastasis.Nature. 2007;448:807-10.
-
(2007)
Nature
, vol.448
, pp. 807-810
-
-
Ji, H.1
Ramsey, M.R.2
Hayes, D.N.3
-
69
-
-
70449526719
-
Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility
-
Giampieri S,Manning C,Hooper S,Jones L,Hill CS,Sahai E.Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility.Nat Cell Biol. 2009;11:1287-96.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1287-1296
-
-
Giampieri, S.1
Manning, C.2
Hooper, S.3
Jones, L.4
Hill, C.S.5
Sahai, E.6
-
70
-
-
54549088877
-
Rac activation and inactivation control plasticity of tumor cell movement
-
Sanz-Moreno V,Gadea G,Ahn J, et al.Rac activation and inactivation control plasticity of tumor cell movement.Cell. 2008;135:510-23.
-
(2008)
Cell
, vol.135
, pp. 510-523
-
-
Sanz-Moreno, V.1
Gadea, G.2
Ahn, J.3
-
71
-
-
77955470270
-
Regulation of invasive behavior by vascular endothelial growth factor is HEF1-dependent
-
Lucas JT,Salimath BP,Slomiany MG,Rosenzweig SA.Regulation of invasive behavior by vascular endothelial growth factor is HEF1-dependent.Oncogene. 2010;29:4449-59.
-
(2010)
Oncogene
, vol.29
, pp. 4449-4459
-
-
Lucas, J.T.1
Salimath, B.P.2
Slomiany, M.G.3
Rosenzweig, S.A.4
-
72
-
-
77952863907
-
Human enhancer of filamentation 1 Is a mediator of hypoxia-inducible factor-1alpha-mediated migration in colorectal carcinoma cells
-
Kim SH,Xia D,Kim SW,Holla V,Menter DG,Dubois RN.Human enhancer of filamentation 1 Is a mediator of hypoxia-inducible factor-1alpha-mediated migration in colorectal carcinoma cells.Cancer Res. 2010;70:4054-63.
-
(2010)
Cancer Res
, vol.70
, pp. 4054-4063
-
-
Kim, S.H.1
Xia, D.2
Kim, S.W.3
Holla, V.4
Menter, D.G.5
Dubois, R.N.6
-
73
-
-
84862777514
-
RAC1 activation mediates Twist1-induced cancer cell migration
-
Yang WH,Lan HY,Huang CH, et al.RAC1 activation mediates Twist1-induced cancer cell migration.Nat Cell Biol. 2012;14:366-74.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 366-374
-
-
Yang, W.H.1
Lan, H.Y.2
Huang, C.H.3
-
74
-
-
70349747017
-
NEDD9 promotes oncogenic signaling in mammary tumor development
-
Izumchenko E,Singh MK,Plotnikova OV, et al.NEDD9 promotes oncogenic signaling in mammary tumor development.Cancer Res. 2009;69:7198-206.
-
(2009)
Cancer Res
, vol.69
, pp. 7198-7206
-
-
Izumchenko, E.1
Singh, M.K.2
Plotnikova, O.V.3
-
75
-
-
78449302370
-
Enhanced genetic instability and dasatinib sensitivity in mammary tumor cells lacking NEDD9
-
Singh MK,Izumchenko E,Klein-Szanto AJ,Egleston BL,Wolfson M,Golemis EA.Enhanced genetic instability and dasatinib sensitivity in mammary tumor cells lacking NEDD9.Cancer Res. 2010;70:8907-16.
-
(2010)
Cancer Res
, vol.70
, pp. 8907-8916
-
-
Singh, M.K.1
Izumchenko, E.2
Klein-Szanto, A.J.3
Egleston, B.L.4
Wolfson, M.5
Golemis, E.A.6
-
76
-
-
44949179470
-
A novel Cas family member, HEPL, regulates FAK and cell spreading
-
Singh MK,Dadke D,Nicolas E, et al.A novel Cas family member, HEPL, regulates FAK and cell spreading.Mol Biol Cell. 2008;19:1627-36.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 1627-1636
-
-
Singh, M.K.1
Dadke, D.2
Nicolas, E.3
-
77
-
-
70350431772
-
Regulation of T-lymphocyte physiology by the Chat-H/CasL adapter complex
-
Alexandropoulos K,Regelmann AG.Regulation of T-lymphocyte physiology by the Chat-H/CasL adapter complex.Immunol Rev. 2009;232:160-74.
-
(2009)
Immunol Rev
, vol.232
, pp. 160-174
-
-
Alexandropoulos, K.1
Regelmann, A.G.2
-
78
-
-
33847626335
-
Splice variants and expression patterns of SHEP1, BCAR3 and NSP1, a gene family involved in integrin and receptor tyrosine kinase signaling
-
Vervoort VS,Roselli S,Oshima RG,Pasquale EB.Splice variants and expression patterns of SHEP1, BCAR3 and NSP1, a gene family involved in integrin and receptor tyrosine kinase signaling.Gene. 2007;391:161-70.
-
(2007)
Gene
, vol.391
, pp. 161-170
-
-
Vervoort, V.S.1
Roselli, S.2
Oshima, R.G.3
Pasquale, E.B.4
-
79
-
-
33845490019
-
The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking
-
Regelmann AG,Danzl NM,Wanjalla C,Alexandropoulos K.The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking.Immunity. 2006;25:907-18.
-
(2006)
Immunity
, vol.25
, pp. 907-918
-
-
Regelmann, A.G.1
Danzl, N.M.2
Wanjalla, C.3
Alexandropoulos, K.4
-
80
-
-
0033527649
-
A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A
-
Dodelet VC,Pazzagli C,Zisch AH,Hauser CA,Pasquale EB.A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A.J Biol Chem. 1999;274:31941-6.
-
(1999)
J Biol Chem
, vol.274
, pp. 31941-31946
-
-
Dodelet, V.C.1
Pazzagli, C.2
Zisch, A.H.3
Hauser, C.A.4
Pasquale, E.B.5
-
81
-
-
0033537975
-
NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway
-
Lu Y,Brush J,Stewart TA.NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway.J Biol Chem. 1999;274:10047-52.
-
(1999)
J Biol Chem
, vol.274
, pp. 10047-10052
-
-
Lu, Y.1
Brush, J.2
Stewart, T.A.3
-
82
-
-
30544449081
-
A quantitative protein interaction network for the ErbB receptors using protein microarrays
-
Jones RB,Gordus A,Krall JA,MacBeath G.A quantitative protein interaction network for the ErbB receptors using protein microarrays.Nature. 2006;439:168-74.
-
(2006)
Nature
, vol.439
, pp. 168-174
-
-
Jones, R.B.1
Gordus, A.2
Krall, J.A.3
MacBeath, G.4
-
83
-
-
50849088326
-
BCAR3 regulates EGF-induced DNA synthesis in normal human breast MCF-12A cells
-
Oh MJ,van Agthoven T,Choi JE, et al.BCAR3 regulates EGF-induced DNA synthesis in normal human breast MCF-12A cells.Biochem Biophys Res Commun. 2008;375:430-4.
-
(2008)
Biochem Biophys Res Commun
, vol.375
, pp. 430-434
-
-
Oh, M.J.1
van Agthoven, T.2
Choi, J.E.3
-
84
-
-
79959541003
-
The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function
-
Murphy DA,Courtneidge SA.The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function.Nat Rev Mol Cell Biol. 2011;12:413-26.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 413-426
-
-
Murphy, D.A.1
Courtneidge, S.A.2
-
85
-
-
0033566368
-
AND-34, a novel p130Cas-binding thymic stromal cell protein regulated by adhesion and inflammatory cytokines
-
Cai D,Clayton LK,Smolyar A,Lerner A.AND-34, a novel p130Cas-binding thymic stromal cell protein regulated by adhesion and inflammatory cytokines.J Immunol. 1999;163:2104-12.
-
(1999)
J Immunol
, vol.163
, pp. 2104-2112
-
-
Cai, D.1
Clayton, L.K.2
Smolyar, A.3
Lerner, A.4
-
86
-
-
0034052103
-
Chat, a Cas/HEF1-associated adaptor protein that integrates multiple signaling pathways
-
Sakakibara A,Hattori S.Chat, a Cas/HEF1-associated adaptor protein that integrates multiple signaling pathways.J Biol Chem. 2000;275:6404-10.
-
(2000)
J Biol Chem
, vol.275
, pp. 6404-6410
-
-
Sakakibara, A.1
Hattori, S.2
-
87
-
-
0034730244
-
p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor
-
Gotoh T,Cai D,Tian X,Feig LA,Lerner A.p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.J Biol Chem. 2000;275:30118-23.
-
(2000)
J Biol Chem
, vol.275
, pp. 30118-30123
-
-
Gotoh, T.1
Cai, D.2
Tian, X.3
Feig, L.A.4
Lerner, A.5
-
88
-
-
0037458030
-
Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry
-
Salomon AR,Ficarro SB,Brill LM, et al.Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry.Proc Natl Acad Sci U S A. 2003;100:443-8.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 443-448
-
-
Salomon, A.R.1
Ficarro, S.B.2
Brill, L.M.3
-
89
-
-
0041845239
-
Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3
-
Riggins RB,Quilliam LA,Bouton AH.Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3.J Biol Chem. 2003;278:28264-73.
-
(2003)
J Biol Chem
, vol.278
, pp. 28264-28273
-
-
Riggins, R.B.1
Quilliam, L.A.2
Bouton, A.H.3
-
90
-
-
4744373997
-
SHEP1 function in cell migration is impaired by a single amino acid mutation that disrupts association with the scaffolding protein cas but not with Ras GTPases
-
Dail M,Kalo MS,Seddon JA,Cote JF,Vuori K,Pasquale EB.SHEP1 function in cell migration is impaired by a single amino acid mutation that disrupts association with the scaffolding protein cas but not with Ras GTPases.J Biol Chem. 2004;279:41892-902.
-
(2004)
J Biol Chem
, vol.279
, pp. 41892-41902
-
-
Dail, M.1
Kalo, M.S.2
Seddon, J.A.3
Cote, J.F.4
Vuori, K.5
Pasquale, E.B.6
-
91
-
-
60849096378
-
Src-dependent repression of ARF6 is required to maintain podosome-rich sealing zones in bone-digesting osteoclasts
-
Heckel T,Czupalla C,Expirto Santo AI, et al.Src-dependent repression of ARF6 is required to maintain podosome-rich sealing zones in bone-digesting osteoclasts.Proc Natl Acad Sci U S A. 2009;106:1451-6.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1451-1456
-
-
Heckel, T.1
Czupalla, C.2
Expirto Santo, A.I.3
-
92
-
-
12244263457
-
Novel function of Chat in controlling cell adhesion via Cas-Crk-C3G-pathway- mediated Rap1 activation
-
Sakakibara A,Ohba Y,Kurokawa K,Matsuda M,Hattori S.Novel function of Chat in controlling cell adhesion via Cas-Crk-C3G-pathway- mediated Rap1 activation.J Cell Sci. 2002;115:4915-24.
-
(2002)
J Cell Sci
, vol.115
, pp. 4915-4924
-
-
Sakakibara, A.1
Ohba, Y.2
Kurokawa, K.3
Matsuda, M.4
Hattori, S.5
-
93
-
-
67349209683
-
Loss of AND-34/BCAR3 expression in mice results in rupture of the adult lens
-
Near RI,Smith RS,Toselli PA, et al.Loss of AND-34/BCAR3 expression in mice results in rupture of the adult lens.Mol Vis. 2009;15:685-99.
-
(2009)
Mol Vis
, vol.15
, pp. 685-699
-
-
Near, R.I.1
Smith, R.S.2
Toselli, P.A.3
-
94
-
-
67349235909
-
AND-34/BCAR3 regulates adhesion-dependent p130Cas serine phosphorylation and breast cancer cell growth pattern
-
Makkinje A,Near RI,Infusini G, et al.AND-34/BCAR3 regulates adhesion-dependent p130Cas serine phosphorylation and breast cancer cell growth pattern.Cell Signal. 2009;21:1423-35.
-
(2009)
Cell Signal
, vol.21
, pp. 1423-1435
-
-
Makkinje, A.1
Near, R.I.2
Infusini, G.3
-
96
-
-
77955656437
-
The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein Cas
-
Roselli S,Wallez Y,Wang L,Vervoort V,Pasquale EB.The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein Cas.Cell Signal. 2010;22:1745-52.
-
(2010)
Cell Signal
, vol.22
, pp. 1745-1752
-
-
Roselli, S.1
Wallez, Y.2
Wang, L.3
Vervoort, V.4
Pasquale, E.B.5
-
97
-
-
77957374878
-
The SRC homology 2 domain protein shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain
-
Wang L,Vervoort V,Wallez Y,Core N,Cremer H,Pasquale EB.The SRC homology 2 domain protein shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain.J Neurosci. 2010;30:13201-10.
-
(2010)
J Neurosci
, vol.30
, pp. 13201-13210
-
-
Wang, L.1
Vervoort, V.2
Wallez, Y.3
Core, N.4
Cremer, H.5
Pasquale, E.B.6
-
98
-
-
79952698124
-
BCAR3/AND-34 can signal independent of complex formation with CAS family members or the presence of p130Cas
-
Vanden Borre P,Near RI,Makkinje A,Mostoslavsky G,Lerner A.BCAR3/AND-34 can signal independent of complex formation with CAS family members or the presence of p130Cas.Cell Signal. 2011;23:1030-40.
-
(2011)
Cell Signal
, vol.23
, pp. 1030-1040
-
-
Vanden Borre, P.1
Near, R.I.2
Makkinje, A.3
Mostoslavsky, G.4
Lerner, A.5
-
99
-
-
84864984755
-
Breast cancer anti-estrogen resistance 3 (BCAR3) augments binding of the c-Src kinase SH3 domain to Crk-associated substrate (p130Cas)
-
Makkinje A,Vanden Borre P,Near RI,Patel PS,Lerner A.Breast cancer anti-estrogen resistance 3 (BCAR3) augments binding of the c-Src kinase SH3 domain to Crk-associated substrate (p130Cas).J Biol Chem. 2012;287:27703-14.
-
(2012)
J Biol Chem
, vol.287
, pp. 27703-27714
-
-
Makkinje, A.1
Vanden Borre, P.2
Near, R.I.3
Patel, P.S.4
Lerner, A.5
-
100
-
-
0037438577
-
The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42
-
Cai D,Felekkis KN,Near RI, et al.The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42.J Immunol. 2003;170:969-78.
-
(2003)
J Immunol
, vol.170
, pp. 969-978
-
-
Cai, D.1
Felekkis, K.N.2
Near, R.I.3
-
101
-
-
0142219882
-
AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter
-
Cai D,Iyer A,Felekkis KN, et al.AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter.Cancer Res. 2003;63:6802-8.
-
(2003)
Cancer Res
, vol.63
, pp. 6802-6808
-
-
Cai, D.1
Iyer, A.2
Felekkis, K.N.3
-
102
-
-
13244273515
-
AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner
-
Felekkis KN,Narsimhan RP,Near R, et al.AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner.Mol Cancer Res. 2005;3:32-41.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 32-41
-
-
Felekkis, K.N.1
Narsimhan, R.P.2
Near, R.3
-
103
-
-
34547932906
-
AND-34/BCAR3 differs from other NSP homologs in induction of anti-estrogen resistance, cyclin D1 promoter activation and altered breast cancer cell morphology
-
Near RI,Zhang Y,Makkinje A,Vanden Borre P,Lerner A.AND-34/BCAR3 differs from other NSP homologs in induction of anti-estrogen resistance, cyclin D1 promoter activation and altered breast cancer cell morphology.J Cell Physiol. 2007;212:655-65.
-
(2007)
J Cell Physiol
, vol.212
, pp. 655-665
-
-
Near, R.I.1
Zhang, Y.2
Makkinje, A.3
Vanden Borre, P.4
Lerner, A.5
-
104
-
-
0037458572
-
A novel hematopoietic adaptor protein, Chat-H, positively regulates T cell receptor-mediated interleukin-2 production by Jurkat cells
-
Sakakibara A,Hattori S,Nakamura S,Katagiri T.A novel hematopoietic adaptor protein, Chat-H, positively regulates T cell receptor-mediated interleukin-2 production by Jurkat cells.J Biol Chem. 2003;278:6012-7.
-
(2003)
J Biol Chem
, vol.278
, pp. 6012-6017
-
-
Sakakibara, A.1
Hattori, S.2
Nakamura, S.3
Katagiri, T.4
-
105
-
-
65649108558
-
A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival
-
Singh A,Greninger P,Rhodes D, et al.A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival.Cancer Cell. 2009;15:489-500.
-
(2009)
Cancer Cell
, vol.15
, pp. 489-500
-
-
Singh, A.1
Greninger, P.2
Rhodes, D.3
-
106
-
-
0032525138
-
Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells
-
van Agthoven T,van Agthoven TL,Dekker A,van der Spek PJ,Vreede L,Dorssers LC.Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells.EMBO J. 1998;17:2799-808.
-
(1998)
EMBO J
, vol.17
, pp. 2799-2808
-
-
van Agthoven, T.1
van Agthoven, T.L.2
Dekker, A.3
van der Spek, P.J.4
Vreede, L.5
Dorssers, L.C.6
-
107
-
-
34447122558
-
Breast cancer antiestrogen resistance-3 expression regulates breast cancer cell migration through promotion of p130Cas membrane localization and membrane ruffling
-
Schrecengost RS,Riggins RB,Thomas KS,Guerrero MS,Bouton AH.Breast cancer antiestrogen resistance-3 expression regulates breast cancer cell migration through promotion of p130Cas membrane localization and membrane ruffling.Cancer Res. 2007;67:6174-82.
-
(2007)
Cancer Res
, vol.67
, pp. 6174-6182
-
-
Schrecengost, R.S.1
Riggins, R.B.2
Thomas, K.S.3
Guerrero, M.S.4
Bouton, A.H.5
-
109
-
-
84865558963
-
Protein pathway activation mapping reveals molecular networks associated with antiestrogen resistance in breast cancer cell lines
-
van Agthoven T,Godinho MF,Wulfkuhle JD,Petricoin EF,Dorssers LC.Protein pathway activation mapping reveals molecular networks associated with antiestrogen resistance in breast cancer cell lines.Int J Cancer. 2012;131:1998-2007.
-
(2012)
Int J Cancer
, vol.131
, pp. 1998-2007
-
-
van Agthoven, T.1
Godinho, M.F.2
Wulfkuhle, J.D.3
Petricoin, E.F.4
Dorssers, L.C.5
-
110
-
-
33746883110
-
Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b
-
Riggins RB,Thomas KS,Ta HQ, et al.Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b.Cancer Res. 2006;66:7007-15.
-
(2006)
Cancer Res
, vol.66
, pp. 7007-7015
-
-
Riggins, R.B.1
Thomas, K.S.2
Ta, H.Q.3
-
111
-
-
34247572006
-
Src, chemoresistance and epithelial to mesenchymal transition: are they related?
-
Shah AN,Gallick GE.Src, chemoresistance and epithelial to mesenchymal transition: are they related?.Anticancer Drugs. 2007;18:371-5.
-
(2007)
Anticancer Drugs
, vol.18
, pp. 371-375
-
-
Shah, A.N.1
Gallick, G.E.2
-
112
-
-
79960182540
-
NEDD9 and BCAR1 negatively regulate E-cadherin membrane localization, and promote E-cadherin degradation
-
Tikhmyanova N,Golemis EA.NEDD9 and BCAR1 negatively regulate E-cadherin membrane localization, and promote E-cadherin degradation.PLoS One. 2011;6:e22102.
-
(2011)
PLoS One
, vol.6
-
-
Tikhmyanova, N.1
Golemis, E.A.2
-
113
-
-
4344705051
-
Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype: inhibition by gefitinib ('Iressa', ZD1839)
-
Hiscox S,Morgan L,Barrow D,Dutkowskil C,Wakeling A,Nicholson RI.Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype: inhibition by gefitinib ('Iressa', ZD1839).Clin Exp Metastasis. 2004;21:201-12.
-
(2004)
Clin Exp Metastasis
, vol.21
, pp. 201-212
-
-
Hiscox, S.1
Morgan, L.2
Barrow, D.3
Dutkowskil, C.4
Wakeling, A.5
Nicholson, R.I.6
-
114
-
-
1342326910
-
Relevance of breast cancer cell lines as models for breast tumours: an update
-
Lacroix M,Leclercq G.Relevance of breast cancer cell lines as models for breast tumours: an update.Breast Cancer Res Treat. 2004;83:249-89.
-
(2004)
Breast Cancer Res Treat
, vol.83
, pp. 249-289
-
-
Lacroix, M.1
Leclercq, G.2
-
115
-
-
33746731130
-
A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands
-
Giallourakis C,Cao Z,Green T, et al.A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands.Genome Res. 2006;16:1056-72.
-
(2006)
Genome Res
, vol.16
, pp. 1056-1072
-
-
Giallourakis, C.1
Cao, Z.2
Green, T.3
-
117
-
-
0346158492
-
The proteomics approach to find biomarkers in gastric cancer
-
Ryu JW,Kim HJ,Lee YS, et al.The proteomics approach to find biomarkers in gastric cancer.J Korean Med Sci. 2003;18:505-9.
-
(2003)
J Korean Med Sci
, vol.18
, pp. 505-509
-
-
Ryu, J.W.1
Kim, H.J.2
Lee, Y.S.3
-
118
-
-
77956194979
-
The adaptor protein Sh2d3c is critical for marginal zone B cell development and function
-
Al-Shami A,Wilkins C,Crisostomo J, et al.The adaptor protein Sh2d3c is critical for marginal zone B cell development and function.J Immunol. 2010;185:327-34.
-
(2010)
J Immunol
, vol.185
, pp. 327-334
-
-
Al-Shami, A.1
Wilkins, C.2
Crisostomo, J.3
-
120
-
-
33644821930
-
Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway
-
Dorssers LC,van Agthoven T,Brinkman A,Veldscholte J,Smid M,Dechering KJ.Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway.Breast Cancer Res. 2005;7:R82-92.
-
(2005)
Breast Cancer Res
, vol.7
-
-
Dorssers, L.C.1
van Agthoven, T.2
Brinkman, A.3
Veldscholte, J.4
Smid, M.5
Dechering, K.J.6
-
121
-
-
59149094599
-
Relevance of breast cancer antiestrogen resistance genes in human breast cancer progression and tamoxifen resistance
-
van Agthoven T,Sieuwerts AM,Meijer-van Gelder ME, et al.Relevance of breast cancer antiestrogen resistance genes in human breast cancer progression and tamoxifen resistance.J Clin Oncol. 2009;27:542-9.
-
(2009)
J Clin Oncol
, vol.27
, pp. 542-549
-
-
van Agthoven, T.1
Sieuwerts, A.M.2
Meijer-van Gelder, M.E.3
-
122
-
-
84866405687
-
Protein tyrosine phosphatase alpha phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions
-
Sun G,Cheng SY,Chen M,Lim CJ,Pallen CJ.Protein tyrosine phosphatase alpha phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions.Mol Cell Biol. 2012;32:3776-89.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 3776-3789
-
-
Sun, G.1
Cheng, S.Y.2
Chen, M.3
Lim, C.J.4
Pallen, C.J.5
|