AND-34, a novel p130(Cas)-binding thymic stromal cell protein regulated by adhesion and inflammatory cytokines

Journal of Immunology

Volumn 163, Issue 4, 1999, Pages 2104-2112

  Cai, Dongpo ^a,b   Clayton, Linda K ^c,d   Smolyar, Alex ^c,d   Lerner, Adam ^a,b  

^a BOSTON MEDICAL CENTER   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CELL PROTEIN; COMPLEMENTARY DNA; CYTOKINE; FIBRONECTIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; POLYLYSINE; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; VANADATE SODIUM; BCAR1 PROTEIN, MOUSE; BCAR3 PROTEIN, MOUSE; CELL CYCLE PROTEIN; CRK ASSOCIATED SUBSTRATE PROTEIN; INTERLEUKIN 1; PEPTIDE FRAGMENT; PHOSPHOPROTEIN; PROTEIN; PROTEIN P130; TYROSINE;

AMINO ACID SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; FIBROBLAST; HUMAN; HUMAN CELL; INFLAMMATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; THYMOCYTE; THYMUS; ANIMAL; C57BL MOUSE; CELL ADHESION; CELL STRAIN 3T3; CHEMISTRY; CYTOLOGY; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PROTEIN BINDING; SERODIAGNOSIS; STROMA CELL; TRANSGENIC MOUSE;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL ADHESION; CELL CYCLE PROTEINS; CRK-ASSOCIATED SUBSTRATE PROTEIN; CYTOKINES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INTERLEUKIN-1; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PRECIPITIN TESTS; PROTEIN BINDING; PROTEINS; RAS-GRF1; RETINOBLASTOMA-LIKE PROTEIN P130; SEQUENCE HOMOLOGY, AMINO ACID; STROMAL CELLS; THYMUS GLAND; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE;

EID: 0033566368     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Lerner, A., L. K. Clayton, E. Mizoguchi, Y. Ghendler, W. van Ewijk, S. Koyasu, A. K. Bhan, and E. L. Reinherz. 1996. Cross-linking of T cell receptors on double positive thymocytes induces a cytokine-mediated stromal activation process linked to cell death. EMBO J. 15:5876.
2. Zuniga-Pflucker, J. C., D. Jiang, and M. J. Lenardo. 268. Requirement for TNF and IL1 in fetal thymocyte commitment and differentiation. Science 268:1906.
3. Galy, A. H. M., E. M. Hadden, J.-L. Touraine, and J. W. Hadden. 1989. Effects of cytokines on human thymic epithelial cells in culture: IL1 induces thymic epithelial cell proliferation and change in morphology. Cell. Immunol. 124:13.
4. Galy, A. H. M., C. A. Dinarello, T. S. Kupper, A. Kameda, and J. W. Hadden. 1990. Effects of cytokines on human epithelial cells in culture: recombinant IL1 stimulates thymic epithelial cells to produce IL6 and GM-CSF. Cell. Immunol. 129:161.
5. Helle, M., L. Boeije, and L. A. Aarden. 1989. IL-6 is an intermediate in 1L-1-induced thymocyte proliferation. J. Immunol. 12:4335.
6. Faas, S. J., J. L. Rothstein, B. L. Kreider, G. Rovera, and B. B. Knowles. 1993. Phenotypically diverse mouse thymic stromal cells which induce proliferation and differentiation of hematopoietic cells Eur. J. Immunol. 23:1201.
7. Pietrangeli, C. E., S.-I. Hayashi, and P. W. Kincade. 1988. Stromal cell lines which support lymphocyte growth: characterization, sensitivity to radiation and responsiveness to growth factors. Eur. J. Immunol. 18:863.
8. Kozak, M. 1984. Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. Nucleic Acids Res. 12:857.
9. Birnstiel, M. L., M. Busslinger, and K. Strub. 1985 Transcription termination and 3′ processing: the end is in site! Cell 41:349.
10. Koch, C. A., D. Anderson, M. F. Moran, C. Ellis, and T. Pawson. 1991. SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science 252:668.
11. Waksman, G., D. Kominos, S. C. Robertson, N. Pant, D. Baltimore, R. B. Birge, D. Cowburn, H. Hanafusa, B. J. Mayer, M. Overduin, M. D. Resh, C. B. Rios, L. Silverman, and J. Kuriyan. 1992. Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides. Nature 358:646.
12. D'Adamo, D. R., S. Novick, J. M. Kahn, P. Leonardi, and A. Pellicer. 1997. rsc: a novel oncogene with structural and functional homology with the gene family of exchange factors for Ral. Oncogene 14:1295.
13. Boriack-Sjodin, P. A., S. M. Margarit, D. Bar-Sagi, and J. Kuriyan. 1998. The structural basis of the activation of Ras by Sos. Nature 394:337.
14. Rechsteiner, M., and S. W. Rogers. 1996. PEST sequences and regulation by proteolysis. Trends Biochem. Sci. 21:267.
15. van Agthoven, T., T. van Agthoven, A. Dekker, P. Spek, L. Vreede, and L. Dorssers. 1998. Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells. EMBO J. 17:2799.
16. Buday, L., and J. Downward. 1993. Epidermal growth factor regulates p21 Ras through the formation of a complex of receptor, GRB2 adapter protein, and SOS nucleotide exchange factor. Cell 73:611.
17. Egan, S. E., B. W. Giddings, M. W. Brooks, L. Buday, A. M. Sizeland, and R. A. Weinberg. 1993. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363:45.
18. Rinke de Wit, T., D. J. Izon, C. Revilla, M. Osterwegel, A. Q. Bakker, W. van Ewijk, and A. M. Kruisbeek. 1996. Expression of tyrosine kinase genes in mouse thymic stromal cells. Int. Immunol. 8:1787.
19. Matsuda, M., B. J. Mayer, Y. Fukui, and H. Hanafusa. 1990. Binding of transforming protein, p47gag-crk, to a broad range of phosphotyrosine-containing proteins. Science 248:1537.
20. Kanner, S. B., A. B. Reynolds, H.-C. R. Wang, R. R. Vines, and J. T. Parsons. 1991. The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110. EMBO J. 10:1689.
21. Sakai, R., A. Iwamatsu, N. Hirano, S. Ogawa, T. Tanaka, H. Mano, Y. Yazaki, and H. Hirai. 1994. A novel signalling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner. EMBO J. 13:3748.
22. Cas to SH2 and SH3 domains of Src kinase. J. Biol. Chem. 271:8959.
23. Cas. Proc. Natl. Acad. Sci. USA 92:10678.
24. Cas. J. Biol. Chem. 272:228.
25. Cas. J. Biol. Chem. 271:31290.
26. Cas: a novel mechanism of protein tyrosine phosphatase substrate recognition. Oncogene 15:877.
27. Cas to the guanine nucleotide exchange factor C3G. J. Biol. Chem. 273: 25673.
28. Cas, a SH3-containing molecule having multiple SH2 motifs. J. Biol. Chem. 270:15398.
29. Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix. J. Biol. Chem. 270:22259.
30. Cas) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. J. Biol. Chem. 272:5501.
31. Cas to focal adhesions. Mol. Cell. Biol. 17:3884.
32. Needham, L. K., and E. Rozengurt. 1998. G α 12 and G α 13 stimulate rhodependent tyrosine phosphorylation of focal adhesion kinase, paxillin and p130 Crk-associated substrate. J. Biol. Chem. 273:14626.
33. Cas, focal adhesion kinase and paxillin. J. Biol. Chem. 273:26149.
34. Rankin, S., and E. Rozengurt. 1994. Platelet-derived growth factor modulation of focal adhesion kinase (p125FAK) and paxillin tyrosine phosphorylation in Swiss 3T3 cells. J. Biol. Chem. 269:704.
35. Zachary, I., J. Sinnett-Smith, and E. Rozengurt. 1992. Bombesin, vasopressin, and endothelin stimulation of tyrosine phosphorylation in Swiss 3T3 cells. J. Biol. Chem. 267:19031.
36. Cas and CrkII. J. Biol. Chem. 273:33864.
37. Leeb-Lundberg, L., S.-H. Song, and S. A. Mathis. 1994. Focal adhesion-associated proteins p125FAK and paxillin are substrates for bradykinin-stimulated tyrosine phosphorylation in Swiss 3T3 cells. J. Biol. Chem. 269:24328.
38. Schlaepfer, D. D., K. C. Jones, and T. Hunter. 1998. Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events. Mol. Cell. Biol. 18:2571.
39. Tanaka, S., and H. Hanafusa. 1998. Guanine-nucleotide exchange protein C3G activates JNK1 by a Ras-independent mechanism. J. Biol. Chem. 273:1281.
40. Lo, Y., L. Luo, C. McCulloch, and T. F. Cruz. 1998. Requirements of focal adhesions and calcium fluxes for Interleukin-1-induced ERK kinase activation and c-fos expression in fibroblasts J. Biol. Chem. 273:7059.
41. Qwarnstrom, E. E., R. C. Page, S. Gillis, and S. K. Dower. 1988. Binding, internalization and intracellular localization of interleukin 1β in human diploid fibroblasts. J. Biol. Chem. 263:8261.
42. Qwarnstrom, E. E., S. A. MacFarlane, R. C. Page, and S. K. Dower. 1991. Interleukin 1β induces rapid phosphorylation and redistribution of talin: a possible mechanism for modulation of fibroblast focal adhesion. Proc. Natl. Acad. Sci. USA 88:1232.