p130Cas is required for mammary tumor growth and transforming growth factor-β-mediated metastasis through regulation of Smad2/3 activity

Journal of Biological Chemistry

Volumn 284, Issue 49, 2009, Pages 34145-34156

  Wendt, Michael K ^a   Smith, Jason A ^a   Schiemann, William P ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER; CARBOXYL TERMINUS; FOCAL ADHESIONS; FUNDAMENTAL CHANGES; GROWTH ARREST; GROWTH INHIBITION; IN-VITRO; MAMMARY EPITHELIAL CELLS; MAMMARY TUMORS; ORGANOTYPIC CULTURE; P38 MAPK; SIGNALING SYSTEMS; TRANSFORMING GROWTH FACTORS; TUMOR SUPPRESSORS;

BIOACTIVITY; CELL CULTURE; ENZYME INHIBITION; PATHOLOGY; PEPTIDES; TUMORS;

SIGNALING;

CRK ASSOCIATED SUBSTRATE PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; BREAST METASTASIS; BREAST TUMOR; CANCER GROWTH; GENE CONTROL; HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CRK-ASSOCIATED SUBSTRATE PROTEIN; DISEASE PROGRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAMMARY NEOPLASMS, ANIMAL; MICE; NEOPLASM METASTASIS; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

MUS;

EID: 71749099201     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.023614     Document Type: Article

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