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Volumn 106, Issue 5, 2009, Pages 1451-1456

Src-dependent repression of ARF6 is required to maintain podosome-rich sealing zones in bone-digesting osteoclasts

Author keywords

GIT2; Podosomes; Polarity; Quantitative proteomics

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 6; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PROTEIN TYROSINE KINASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; ADP-RIBOSYLATION FACTOR 6; CELL CYCLE PROTEIN; GIT2 PROTEIN, MOUSE; GUANOSINE TRIPHOSPHATE; PHOSPHOPROTEIN;

EID: 60849096378     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0804464106     Document Type: Article
Times cited : (48)

References (38)
  • 1
    • 0038433238 scopus 로고    scopus 로고
    • Podosomes: Adhesion hot-spots of invasive cells
    • Linder S, Aepfelbacher M (2003) Podosomes: Adhesion hot-spots of invasive cells. Trends Cell Biol 13:376-385.
    • (2003) Trends Cell Biol , vol.13 , pp. 376-385
    • Linder, S.1    Aepfelbacher, M.2
  • 2
    • 55249119822 scopus 로고    scopus 로고
    • The architecture of the adhesive apparatus of cultured osteoclasts: From podosome formation to sealing zone assembly
    • Luxenburg C, et al. (2007) The architecture of the adhesive apparatus of cultured osteoclasts: From podosome formation to sealing zone assembly. PLoS ONE 2:e179.
    • (2007) PLoS ONE , vol.2
    • Luxenburg, C.1
  • 3
    • 33644950260 scopus 로고    scopus 로고
    • Podosome and sealing zone: Specificity of the osteoclast model
    • Jurdic P, Saltel F, Chabadel A, Destaing O (2006) Podosome and sealing zone: Specificity of the osteoclast model. Eur J Cell Biol 85:195-202.
    • (2006) Eur J Cell Biol , vol.85 , pp. 195-202
    • Jurdic, P.1    Saltel, F.2    Chabadel, A.3    Destaing, O.4
  • 4
  • 6
    • 0029786988 scopus 로고    scopus 로고
    • Knockouts of Src-family kinases: Stiff bones, wimpy T cells, and bad memories
    • Lowell CA, Soriano P (1996) Knockouts of Src-family kinases: Stiff bones, wimpy T cells, and bad memories. Genes Dev 10:1845-1857.
    • (1996) Genes Dev , vol.10 , pp. 1845-1857
    • Lowell, C.A.1    Soriano, P.2
  • 7
    • 0035374609 scopus 로고    scopus 로고
    • The hunting of the Src
    • Martin GS (2001) The hunting of the Src. Nature Reviews 2:467-475.
    • (2001) Nature Reviews , vol.2 , pp. 467-475
    • Martin, G.S.1
  • 8
    • 0030856131 scopus 로고    scopus 로고
    • Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice
    • Schwartzberg PL, et al. (1997) Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice. Genes Dev 11:2835-2844.
    • (1997) Genes Dev , vol.11 , pp. 2835-2844
    • Schwartzberg, P.L.1
  • 9
    • 2342442847 scopus 로고    scopus 로고
    • Src kinase activity is essential for osteoclast function
    • Miyazaki T, et al. (2004) Src kinase activity is essential for osteoclast function. J Biol Chem 279:17660-17666.
    • (2004) J Biol Chem , vol.279 , pp. 17660-17666
    • Miyazaki, T.1
  • 10
    • 33947240223 scopus 로고    scopus 로고
    • Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption
    • Zou W, et al. (2007) Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption. J Cell Biol 176:877-888.
    • (2007) J Cell Biol , vol.176 , pp. 877-888
    • Zou, W.1
  • 11
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle WJ, Simonet WS, Lacey DL (2003) Osteoclast differentiation and activation. Nature 423:337-342.
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 12
    • 0037329229 scopus 로고    scopus 로고
    • Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein
    • Destaing O, Saltel F, Geminard JC, Jurdic P, Bard F (2003) Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein. Mol Biol Cell 14:407-416.
    • (2003) Mol Biol Cell , vol.14 , pp. 407-416
    • Destaing, O.1    Saltel, F.2    Geminard, J.C.3    Jurdic, P.4    Bard, F.5
  • 13
    • 0037936890 scopus 로고    scopus 로고
    • From lysosomes to the plasma membrane: Localization of vacuolar-type H+ -ATPase with the a3 isoform during osteoclast differentiation
    • Toyomura T, et al. (2003) From lysosomes to the plasma membrane: Localization of vacuolar-type H+ -ATPase with the a3 isoform during osteoclast differentiation. J Biol Chem 278:22023-22030.
    • (2003) J Biol Chem , vol.278 , pp. 22023-22030
    • Toyomura, T.1
  • 14
    • 0036583926 scopus 로고    scopus 로고
    • Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
    • Ong SE, et al. (2002) Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics 1:376-386.
    • (2002) Mol Cell Proteomics , vol.1 , pp. 376-386
    • Ong, S.E.1
  • 15
    • 0033582480 scopus 로고    scopus 로고
    • Stable association of PYK2 and p130(Cas) in osteoclasts and their co-localization in the sealing zone
    • Lakkakorpi PT, et al. (1999) Stable association of PYK2 and p130(Cas) in osteoclasts and their co-localization in the sealing zone. J Biol Chem 274:4900-4907.
    • (1999) J Biol Chem , vol.274 , pp. 4900-4907
    • Lakkakorpi, P.T.1
  • 16
    • 0034730244 scopus 로고    scopus 로고
    • p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor
    • Gotoh T, Cai D, Tian X, Feig LA, Lerner A (2000) p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor. J Biol Chem 275:30118-30123.
    • (2000) J Biol Chem , vol.275 , pp. 30118-30123
    • Gotoh, T.1    Cai, D.2    Tian, X.3    Feig, L.A.4    Lerner, A.5
  • 17
    • 33744981370 scopus 로고    scopus 로고
    • HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse
    • Gomez TS, et al. (2006) HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse. Immunity 24:741-752.
    • (2006) Immunity , vol.24 , pp. 741-752
    • Gomez, T.S.1
  • 18
    • 33646705915 scopus 로고    scopus 로고
    • The multifunctional GIT family of proteins
    • Hoefen RJ, Berk BC (2006) The multifunctional GIT family of proteins. J Cell Sci 119(Pt 8):1469-1475.
    • (2006) J Cell Sci , vol.119 , Issue.PART 8 , pp. 1469-1475
    • Hoefen, R.J.1    Berk, B.C.2
  • 19
    • 0035475321 scopus 로고    scopus 로고
    • Paxillin: A focal adhesion-associated adaptor protein
    • Schaller MD (2001) Paxillin: A focal adhesion-associated adaptor protein. Oncogene 20:6459-6472.
    • (2001) Oncogene , vol.20 , pp. 6459-6472
    • Schaller, M.D.1
  • 20
    • 0029907265 scopus 로고    scopus 로고
    • A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation
    • Dikic I, Tokiwa G, Lev S, Courtneidge SA, Schlessinger J (1996) A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation. Nature 383:547-550.
    • (1996) Nature , vol.383 , pp. 547-550
    • Dikic, I.1    Tokiwa, G.2    Lev, S.3    Courtneidge, S.A.4    Schlessinger, J.5
  • 21
    • 0036631548 scopus 로고    scopus 로고
    • VAV proteins as signal integrators for multi-subunit immune-recognition receptors
    • Turner M, Billadeau DD (2002) VAV proteins as signal integrators for multi-subunit immune-recognition receptors. Nat Rev Immunol 2:476-486.
    • (2002) Nat Rev Immunol , vol.2 , pp. 476-486
    • Turner, M.1    Billadeau, D.D.2
  • 22
    • 33749242977 scopus 로고    scopus 로고
    • PAK4 and αPIX determine podosome size and number in macrophages through localized actin regulation
    • Gringel A, et al. (2006) PAK4 and αPIX determine podosome size and number in macrophages through localized actin regulation. J Cell Phys 209:568-579.
    • (2006) J Cell Phys , vol.209 , pp. 568-579
    • Gringel, A.1
  • 23
    • 33646184680 scopus 로고    scopus 로고
    • ARF proteins: Roles in membrane traffic and beyond
    • D'Souza-Schorey C, Chavrier P (2006) ARF proteins: Roles in membrane traffic and beyond. Nature Reviews 7:347-358.
    • (2006) Nature Reviews , vol.7 , pp. 347-358
    • D'Souza-Schorey, C.1    Chavrier, P.2
  • 24
    • 33845313646 scopus 로고    scopus 로고
    • Heo WD, et al. (2006) PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane. Science 314:1458-1461.
    • Heo WD, et al. (2006) PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane. Science 314:1458-1461.
  • 25
    • 33748312025 scopus 로고    scopus 로고
    • ArfGAP family proteins in cell adhesion, migration and tumor invasion
    • Sabe H, Onodera Y, Mazaki Y, Hashimoto S (2006) ArfGAP family proteins in cell adhesion, migration and tumor invasion. Curr Opin Cell Biol 18:558-564.
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 558-564
    • Sabe, H.1    Onodera, Y.2    Mazaki, Y.3    Hashimoto, S.4
  • 26
    • 24344508125 scopus 로고    scopus 로고
    • Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness
    • Brown MC, Cary LA, Jamieson JS, Cooper JA, Turner CE (2005) Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness. Mol Biol Cell 16:4316-4328.
    • (2005) Mol Biol Cell , vol.16 , pp. 4316-4328
    • Brown, M.C.1    Cary, L.A.2    Jamieson, J.S.3    Cooper, J.A.4    Turner, C.E.5
  • 27
    • 33646566846 scopus 로고    scopus 로고
    • GIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnover
    • Frank SR, Adelstein MR, Hansen SH (2006)GIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnover. EMBO J 25:1848-1859.
    • (2006) EMBO J , vol.25 , pp. 1848-1859
    • Frank, S.R.1    Adelstein, M.R.2    Hansen, S.H.3
  • 28
    • 33847343034 scopus 로고    scopus 로고
    • The matrix corroded: Podosomes and invadopodia in extracellular matrix degradation
    • Linder S (2007) The matrix corroded: Podosomes and invadopodia in extracellular matrix degradation. Trends Cell Biol 17(3):107-117.
    • (2007) Trends Cell Biol , vol.17 , Issue.3 , pp. 107-117
    • Linder, S.1
  • 29
    • 3543114271 scopus 로고    scopus 로고
    • Foot and mouth: Podosomes, invadopodia and circular dorsal ruffles
    • Buccione R, Orth JD, McNiven MA (2004) Foot and mouth: Podosomes, invadopodia and circular dorsal ruffles. Nat Rev Mol Cell Biol 5:647-657.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 647-657
    • Buccione, R.1    Orth, J.D.2    McNiven, M.A.3
  • 30
    • 2342616300 scopus 로고    scopus 로고
    • Requirement for Arf6 in breast cancer invasive activities
    • Hashimoto S, et al. (2004) Requirement for Arf6 in breast cancer invasive activities. Proc Natl Acad Sci USA 101:6647-6652.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 6647-6652
    • Hashimoto, S.1
  • 31
    • 3042798296 scopus 로고    scopus 로고
    • ADP-ribosylation factor 6 regulates tumor cell invasion through the activation of the MEK/ERK signaling pathway
    • Tague SE, Muralidharan V, D'Souza-Schorey C (2004) ADP-ribosylation factor 6 regulates tumor cell invasion through the activation of the MEK/ERK signaling pathway. Proc Natl Acad Sci USA 101:9671-9676.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 9671-9676
    • Tague, S.E.1    Muralidharan, V.2    D'Souza-Schorey, C.3
  • 32
    • 31944442964 scopus 로고    scopus 로고
    • The Arf6 GEF GEP100/BRAG2 regulates cell adhesion by controlling endocytosis of beta1 integrins
    • Dunphy JL, et al. (2006) The Arf6 GEF GEP100/BRAG2 regulates cell adhesion by controlling endocytosis of beta1 integrins. Curr Biol 16:315-320.
    • (2006) Curr Biol , vol.16 , pp. 315-320
    • Dunphy, J.L.1
  • 33
    • 0035801516 scopus 로고    scopus 로고
    • An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration
    • Palacios F, Price L, Schweitzer J, Collard JG, D'Souza-SchoreyC (2001)An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration. EMBO J 20:4973-4986.
    • (2001) EMBO J , vol.20 , pp. 4973-4986
    • Palacios, F.1    Price, L.2    Schweitzer, J.3    Collard, J.G.4    SchoreyC, D.5
  • 34
    • 11144296871 scopus 로고    scopus 로고
    • Lysosomal targeting of E- cadherin: A unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions
    • Palacios F, Tushir JS, Fujita Y, D'Souza-Schorey C (2005) Lysosomal targeting of E- cadherin: A unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions. Mol Cell Biol 25:389-402.
    • (2005) Mol Cell Biol , vol.25 , pp. 389-402
    • Palacios, F.1    Tushir, J.S.2    Fujita, Y.3    D'Souza-Schorey, C.4
  • 35
    • 27144552054 scopus 로고    scopus 로고
    • Comparative study of protein and mRNA expression during osteoclastogenesis
    • Czupalla C, Mansukoski H, Pursche T, Krause E, Hoflack B (2005) Comparative study of protein and mRNA expression during osteoclastogenesis. Proteomics 5:3868-3875.
    • (2005) Proteomics , vol.5 , pp. 3868-3875
    • Czupalla, C.1    Mansukoski, H.2    Pursche, T.3    Krause, E.4    Hoflack, B.5
  • 36
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD(2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 37
    • 31644441420 scopus 로고    scopus 로고
    • Proteomic analysis of lysosomal acid hydrolases secreted by osteoclasts: Implications for lytic enzyme transport and bone metabolism
    • Czupalla C, et al. (2006) Proteomic analysis of lysosomal acid hydrolases secreted by osteoclasts: implications for lytic enzyme transport and bone metabolism. Mol Cell Proteomics5:134-143.
    • (2006) Mol Cell Proteomics , vol.5 , pp. 134-143
    • Czupalla, C.1
  • 38
    • 20344363684 scopus 로고    scopus 로고
    • Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation
    • KratchmarovaI,Blagoev B, Haack-Sorensen M,Kassem M, Mann M (2005) Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation. Science 308:1472-1477.
    • (2005) Science , vol.308 , pp. 1472-1477
    • Kratchmarova, I.1    Blagoev, B.2    Haack-Sorensen, M.3    Kassem, M.4    Mann, M.5


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