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Volumn 69, Issue 18, 2009, Pages 7198-7206

NEDD9 promotes oncogenic signaling in mammary tumor development

Author keywords

[No Author keywords available]

Indexed keywords

FOCAL ADHESION KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN NEDD9; PROTEIN TYROSINE KINASE; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

EID: 70349747017     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-0795     Document Type: Article
Times cited : (113)

References (51)
  • 1
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature 2000;406:747-752
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 2
    • 38949085187 scopus 로고    scopus 로고
    • The importance of distant metastases in hormone-sensitive breast cancer
    • Rugo HS. The importance of distant metastases in hormone-sensitive breast cancer. Breast 2008;17 Suppl 1:S3-8.
    • (2008) Breast , vol.17 , Issue.SUPPL. 1
    • Rugo, H.S.1
  • 3
    • 38049098089 scopus 로고    scopus 로고
    • Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression
    • Lahlou H, Sanguin-Gendreau V, Zuo D, et al. Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression. Proc Natl Acad Sci U S A 2007;104:20302-20307
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 20302-20307
    • Lahlou, H.1    Sanguin-Gendreau, V.2    Zuo, D.3
  • 4
    • 33846416534 scopus 로고    scopus 로고
    • Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/Neu and MMTV-polyoma middle T transgenic mice
    • DOI 10.1158/0008-5472.CAN-06-3782
    • Maroulakou IG, Oemler W, Naber SP, Tsichlis PN. Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice. Cancer Res 2007;67:167-177 (Pubitemid 46142772)
    • (2007) Cancer Research , vol.67 , Issue.1 , pp. 167-177
    • Maroulakou, I.G.1    Oemler, W.2    Naber, S.P.3    Tsichlis, P.N.4
  • 5
    • 40949130063 scopus 로고    scopus 로고
    • ShcA signalling is essential for tumour progression in mouse models of human breast cancer
    • Ursini-Siegel J, Hardy WR, Zuo D, et al. ShcA signalling is essential for tumour progression in mouse models of human breast cancer. EMBO J 2008;27:910-920
    • (2008) EMBO J , vol.27 , pp. 910-920
    • Ursini-Siegel, J.1    Hardy, W.R.2    Zuo, D.3
  • 6
    • 33746764457 scopus 로고    scopus 로고
    • 4 Integrin amplifies ErbB2 signaling to promote mammary tumorigenesis
    • 4 Integrin amplifies ErbB2 signaling to promote mammary tumorigenesis. Cell 2006;126:489-502.
    • (2006) Cell , vol.126 , pp. 489-502
    • Guo, W.1    Pylayeva, Y.2    Pepe, A.3
  • 8
    • 0029904694 scopus 로고    scopus 로고
    • Structure and function of Cas-L, a 105-kD Crk-associated substrate- Related protein that is involved in β1 integrin-mediated signaling in lymphocytes
    • DOI 10.1084/jem.184.4.1365
    • Minegishi M, Tachibana K, Sato T, Iwata S, Nojima Y, Morimoto C. Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in β-1 integrin-mediated signaling in lymphocytes. J Exp Med 1996;184:1365-1375 (Pubitemid 26354693)
    • (1996) Journal of Experimental Medicine , vol.184 , Issue.4 , pp. 1365-1375
    • Minegishi, M.1    Tachibana, K.2    Sato, T.3    Iwata, S.4    Nojima, Y.5    Morimoto, C.6
  • 9
    • 0034959232 scopus 로고    scopus 로고
    • Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics
    • O'Neill GM, Golemis EA. Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics. Mol Cell Biol 2001;21:5094-5108
    • (2001) Mol Cell Biol , vol.21 , pp. 5094-5108
    • O'Neill, G.M.1    Golemis, E.A.2
  • 10
    • 35148825060 scopus 로고    scopus 로고
    • A new central scaffold for metastasis: Parsing HEF1/Cas-L/NEDD9
    • DOI 10.1158/0008-5472.CAN-07-1328
    • O'Neill GM, Seo S, Serebriiskii IG, Lessin SR, Golemis EA. A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9. Cancer Res 2007;67:8975-8979 (Pubitemid 47535876)
    • (2007) Cancer Research , vol.67 , Issue.19 , pp. 8975-8979
    • O'Neill, G.M.1    Seo, S.2    Serebriiskii, I.G.3    Lessin, S.R.4    Golemis, E.A.5
  • 13
    • 54549088877 scopus 로고    scopus 로고
    • Rac activation and inactivation control plasticity of tumor cell movement
    • Sanz-Moreno V, Gadea G, Ahn J, et al. Rac activation and inactivation control plasticity of tumor cell movement. Cell 2008;135:510-523
    • (2008) Cell , vol.135 , pp. 510-523
    • Sanz-Moreno, V.1    Gadea, G.2    Ahn, J.3
  • 15
    • 33645022769 scopus 로고    scopus 로고
    • HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells
    • Natarajan M, Stewart JE, Golemis EA, et al. HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells. Oncogene 2006;25:1721-1732
    • (2006) Oncogene , vol.25 , pp. 1721-1732
    • Natarajan, M.1    Stewart, J.E.2    Golemis, E.A.3
  • 17
    • 0031813880 scopus 로고    scopus 로고
    • Cell cycle-regulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments
    • Law SF, Zhang Y-Z, Klein-Szanto A, Golemis EA. Cell-cycle regulated processing of HEF1 to multiple protein forms differentially targeted to multiple compartments. Mol Cell Biol 1998;18:3540-3551 (Pubitemid 28240526)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.6 , pp. 3540-3551
    • Law, S.F.1    Zhang, Y.-Z.2    Klein-Szanto, A.J.P.3    Golemis, E.A.4
  • 19
    • 51049121572 scopus 로고    scopus 로고
    • Identification of genes that regulate epithelial cell migration using an siRNA screening approach
    • Simpson KJ, Selfors LM, Bui J, et al. Identification of genes that regulate epithelial cell migration using an siRNA screening approach. Nat Cell Biol 2008;10:1027-1038
    • (2008) Nat Cell Biol , vol.10 , pp. 1027-1038
    • Simpson, K.J.1    Selfors, L.M.2    Bui, J.3
  • 20
    • 23144461051 scopus 로고    scopus 로고
    • Genes that mediate breast cancer metastasis to lung
    • Minn AJ, Gupta GP, Siegel PM, et al. Genes that mediate breast cancer metastasis to lung. Nature 2005;436:518-524
    • (2005) Nature , vol.436 , pp. 518-524
    • Minn, A.J.1    Gupta, G.P.2    Siegel, P.M.3
  • 21
    • 8444236025 scopus 로고    scopus 로고
    • The Adenomatous Polyposis coli protein: The achilles heel of the gut epithelium
    • DOI 10.1146/annurev.cellbio.20.012103.094541
    • Nathke IS. The adenomatous polyposis coli protein: the Achilles heel of the gut epithelium. Annu Rev Cell Dev Biol 2004;20:337-366 (Pubitemid 39488642)
    • (2004) Annual Review of Cell and Developmental Biology , vol.20 , pp. 337-366
    • Nathke, I.S.1
  • 23
    • 0036884703 scopus 로고    scopus 로고
    • Polyoma virus middle T antigen and its role in identifying cancer-related molecules
    • Dilworth SM. Polyoma virus middle T antigen and its role in identifying cancer-related molecules. Nat Rev Cancer 2002;2:951-956
    • (2002) Nat Rev Cancer , vol.2 , pp. 951-956
    • Dilworth, S.M.1
  • 24
    • 0142244181 scopus 로고    scopus 로고
    • Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases
    • Lin EY, Jones JG, Li P, et al. Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. Am J Pathol 2003;163:2113-2126 (Pubitemid 37310040)
    • (2003) American Journal of Pathology , vol.163 , Issue.5 , pp. 2113-2126
    • Lin, E.Y.1    Jones, J.G.2    Li, P.3    Zhu, L.4    Whitney, K.D.5    Muller, W.J.6    Pollard, J.W.7
  • 26
    • 0026587657 scopus 로고
    • Induction of mammary tumors by expression of polyomavirus middle T oncogene: A transgenic mouse model for metastatic disease
    • Guy CT, Cardiff RD, Muller WJ. Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol Cell Biol 1992;12:954-961
    • (1992) Mol Cell Biol , vol.12 , pp. 954-961
    • Guy, C.T.1    Cardiff, R.D.2    Muller, W.J.3
  • 28
    • 36849009693 scopus 로고    scopus 로고
    • Improved generalized estimating equation analysis via xtqls for quasileast squares in STATA
    • Shults J, Ratcliffe SJ, Leonard M. Improved generalized estimating equation analysis via xtqls for quasileast squares in STATA. STATA J 2007;7:147-166
    • (2007) STATA J , vol.7 , pp. 147-166
    • Shults, J.1    Ratcliffe, S.J.2    Leonard, M.3
  • 30
    • 27144495462 scopus 로고    scopus 로고
    • The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome
    • Pugacheva EN, Golemis EA. The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome. Nat Cell Biol 2005;7:937-946
    • (2005) Nat Cell Biol , vol.7 , pp. 937-946
    • Pugacheva, E.N.1    Golemis, E.A.2
  • 31
    • 0037082377 scopus 로고    scopus 로고
    • β tyrosine kinase activity-mediated angiogenesis of pulmonary vascular endothelial cells
    • DOI 10.1074/jbc.M110673200
    • Tang H, Hao Q, Fitzgerald T, Sasaki T, Landon EJ, Inagami T. Pyk2/CAKβ tyrosine kinase activity-mediated angiogenesis of pulmonary vascular endothelial cells. J Biol Chem 2002;277:5441-5447 (Pubitemid 34968592)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.7 , pp. 5441-5447
    • Tang, H.1    Hao, Q.2    Fitzgerald, T.3    Sasaki, T.4    Landon, E.J.5    Inagami, T.6
  • 32
    • 0034160011 scopus 로고    scopus 로고
    • Integrin signalling: A new Cas(t) of characters enters the stage
    • DOI 10.1016/S0962-8924(99)01714-6, PII S0962892499017146
    • O'Neill GM, Fashena SJ, Golemis EA. Integrin signaling: a new Cas(t) of characters enters the stage. Trends Cell Biol 2000;10:111-119 (Pubitemid 30110694)
    • (2000) Trends in Cell Biology , vol.10 , Issue.3 , pp. 111-119
    • O'Neill, G.M.1    Fashena, S.J.2    Golemis, E.A.3
  • 33
    • 0033544003 scopus 로고    scopus 로고
    • Dimerization of the docking/adaptor protein HEF1 via a carboxy-terminal helix-loop-helix domain
    • DOI 10.1006/excr.1999.4609
    • Law SF, Zhang Y-Z, Fashena S, Toby G, Estojak J, Golemis EA. Dimerization of the docking/adaptor protein HEF1 via a carboxy-terminal helix-loop-helix domain. Exp Cell Res 1999;252:224-235 (Pubitemid 29485141)
    • (1999) Experimental Cell Research , vol.252 , Issue.1 , pp. 224-235
    • Law, S.F.1    Zhang, Y.-Z.2    Fashena, S.J.3    Toby, G.4    Estojak, J.5    Golemis, E.A.6
  • 36
    • 0034708482 scopus 로고    scopus 로고
    • Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site
    • DOI 10.1074/jbc.275.12.8271
    • Toker A, Newton AC. Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site. J Biol Chem 2000;275:8271-8274 (Pubitemid 30180163)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.12 , pp. 8271-8274
    • Toker, A.1    Newton, A.C.2
  • 37
    • 51849153695 scopus 로고    scopus 로고
    • Expression and tyrosine phosphorylation of Crk-associated substrate lymphocyte type (Cas-L) protein in human neutrophils
    • Nakamoto T, Seo S, Sakai R, et al. Expression and tyrosine phosphorylation of Crk-associated substrate lymphocyte type (Cas-L) protein in human neutrophils. J Cell Biochem 2008;105:121-128
    • (2008) J Cell Biochem , vol.105 , pp. 121-128
    • Nakamoto, T.1    Seo, S.2    Sakai, R.3
  • 40
    • 0029562687 scopus 로고
    • Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which contains a Src homology 3 domain and associates with Fyn
    • Ishino M, Ohba T, Sasaki H, Sasaki T. Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which contains a Src homology 3 domain and associates with Fyn. Oncogene 1995;11:2331-2338 (Pubitemid 26008410)
    • (1995) Oncogene , vol.11 , Issue.11 , pp. 2331-2338
    • Ishino, M.1    Ohba, T.2    Sasaki, H.3    Sasaki, T.4
  • 41
    • 61749094852 scopus 로고    scopus 로고
    • Ras- And PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling
    • Pylayeva Y, Gillen KM, Gerald W, Beggs HE, Reichardt LF, Giancotti FG. Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling. J Clin Invest 2009;119:252-266
    • (2009) J Clin Invest , vol.119 , pp. 252-266
    • Pylayeva, Y.1    Gillen, K.M.2    Gerald, W.3    Beggs, H.E.4    Reichardt, L.F.5    Giancotti, F.G.6
  • 42
    • 52049124532 scopus 로고    scopus 로고
    • Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice
    • Versteeg HH, Schaffner F, Kerver M, et al. Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice. Cancer Res 2008;68:7219-7227
    • (2008) Cancer Res , vol.68 , pp. 7219-7227
    • Versteeg, H.H.1    Schaffner, F.2    Kerver, M.3
  • 43
    • 33747360733 scopus 로고    scopus 로고
    • MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer
    • Cuevas BD, Winter-Vann AM, Johnson NL, Johnson GL. MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer. Oncogene 2006;25:4998-5010.
    • (2006) Oncogene , vol.25 , pp. 4998-5010
    • Cuevas, B.D.1    Winter-Vann, A.M.2    Johnson, N.L.3    Johnson, G.L.4
  • 45
    • 0034671642 scopus 로고    scopus 로고
    • A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1
    • DOI 10.1093/emboj/19.24.6759
    • Liu X, Elia AEH, Law SF, Golemis EA, Farley J, Wang T. A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member, HEF1. EMBO J 2000;19:6759-6769 (Pubitemid 32011669)
    • (2000) EMBO Journal , vol.19 , Issue.24 , pp. 6759-6769
    • Liu, X.1    Elia, A.E.H.2    Law, S.F.3    Golemis, E.A.4    Farley, J.5    Wang, T.6
  • 46
    • 34548357152 scopus 로고    scopus 로고
    • Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle
    • DOI 10.1007/s12013-007-0036-3
    • Singh M, Cowell L, Seo S, O'Neill G, Golemis E. Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle. Cell Biochem Biophys 2007;48:54-72. (Pubitemid 47345633)
    • (2007) Cell Biochemistry and Biophysics , vol.48 , Issue.1 , pp. 54-72
    • Singh, M.K.1    Cowell, L.2    Seo, S.3    O'Neill, G.M.4    Golemis, E.A.5
  • 48
    • 33646422461 scopus 로고    scopus 로고
    • Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis
    • Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis. Cancer Res 2006;66:4672-4680
    • (2006) Cancer Res , vol.66 , pp. 4672-4680
    • Cabodi, S.1    Tinnirello, A.2    Di Stefano, P.3
  • 50
    • 33846326304 scopus 로고    scopus 로고
    • Genetic Screening for Signal Transduction in the Era of Network Biology
    • DOI 10.1016/j.cell.2007.01.007, PII S0092867407000633
    • Friedman A, Perrimon N. Genetic screening for signal transduction in the era of network biology. Cell 2007;128:225-231 (Pubitemid 46123521)
    • (2007) Cell , vol.128 , Issue.2 , pp. 225-231
    • Friedman, A.1    Perrimon, N.2
  • 51
    • 33645220356 scopus 로고    scopus 로고
    • HEF1-aurora a interactions: Points of dialog between the cell cycle and cell attachment signaling networks
    • Pugacheva EN, Golemis EA. HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks. Cell Cycle 2006;5:384-391
    • (2006) Cell Cycle , vol.5 , pp. 384-391
    • Pugacheva, E.N.1    Golemis, E.A.2


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