-
1
-
-
0029766101
-
Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel, p130Cas-related protein, Sin
-
Alexandropoulos, K., and Baltimore, D. (1996). Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel, p130Cas-related protein, Sin. Genes Dev. 10, 1341-1355.
-
(1996)
Genes Dev
, vol.10
, pp. 1341-1355
-
-
Alexandropoulos, K.1
Baltimore, D.2
-
2
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
-
Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D. J. (1997). Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25, 3389-3402.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schaffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
Lipman, D.J.7
-
3
-
-
0033954256
-
The Protein Data Bank
-
Berman, H. M., Westbrook, J., Feng, Z., Gilliland, G., Bhat, T. N., Weissig, H., Shindyalov, I. N., and Bourne, P. E. (2000). The Protein Data Bank. Nucleic Acids Res. 28, 235-242.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
Gilliland, G.4
Bhat, T.N.5
Weissig, H.6
Shindyalov, I.N.7
Bourne, P.E.8
-
4
-
-
20444506822
-
The serine-rich domain from Crk-associated substrate (p130Cas) is a four-helix bundle
-
Briknarova, K., Nasertorabi, F., Havert, M. L., Eggleston, E., Hoyt, D. W., Li, C., Olson, A. J., Vuori, K., and Ely, K. R. (2005). The serine-rich domain from Crk-associated substrate (p130Cas) is a four-helix bundle. J. Biol. Chem. 280, 21908-21914.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 21908-21914
-
-
Briknarova, K.1
Nasertorabi, F.2
Havert, M.L.3
Eggleston, E.4
Hoyt, D.W.5
Li, C.6
Olson, A.J.7
Vuori, K.8
Ely, K.R.9
-
5
-
-
0034684997
-
BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells
-
Brinkman, A., van Der Flier, S., Kok, E. M., and Dorssers, L. C. (2000). BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells. J. Natl. Cancer Inst. 92, 112-120.
-
(2000)
J. Natl. Cancer Inst
, vol.92
, pp. 112-120
-
-
Brinkman, A.1
van Der Flier, S.2
Kok, E.M.3
Dorssers, L.C.4
-
6
-
-
20844462588
-
MolIDE (Molecular Integrated Development Environment): A homology modeling framework you can click with
-
Canutescu, A. A., and Dunbrack, R. L., Jr. (2005). MolIDE (Molecular Integrated Development Environment): a homology modeling framework you can click with. Bioinformatics. 21, 2914-2916.
-
(2005)
Bioinformatics
, vol.21
, pp. 2914-2916
-
-
Canutescu, A.A.1
Dunbrack Jr., R.L.2
-
7
-
-
0042511005
-
A graph-theory algorithm for rapid protein side-chain prediction
-
Canutescu, A. A., Shelenkov, A. A., and Dunbrack, R. L., Jr. (2003). A graph-theory algorithm for rapid protein side-chain prediction. Protein Sci. 12, 2001-2014.
-
(2003)
Protein Sci
, vol.12
, pp. 2001-2014
-
-
Canutescu, A.A.1
Shelenkov, A.A.2
Dunbrack Jr., R.L.3
-
8
-
-
33644868709
-
Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle
-
Dadke, D., Jarnik, M., Pugacheva, E. N., Singh, M. K., and Golemis, E. A. (2006). Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle. Mol. Biol. Cell 17, 1204-1217.
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 1204-1217
-
-
Dadke, D.1
Jarnik, M.2
Pugacheva, E.N.3
Singh, M.K.4
Golemis, E.A.5
-
9
-
-
33646557326
-
p130Cas: A versatile scaffold in signaling networks
-
Defilippi, P., Di Stefano, P., and Cabodi, S. (2006). p130Cas: a versatile scaffold in signaling networks. Trends Cell Biol. 16, 257-263.
-
(2006)
Trends Cell Biol
, vol.16
, pp. 257-263
-
-
Defilippi, P.1
Di Stefano, P.2
Cabodi, S.3
-
10
-
-
44949223784
-
-
Atlas Genet. Cytogenet. Oncol. Haematol, accessed 28 February 2008
-
Dessen, P., Knuutila, S., and Huret, J. L. (2002). Chromosome 20. Atlas Genet. Cytogenet. Oncol. Haematol. http://AtlasGeneticsOncology.org/ Indexbychrom/idxa_Y.html (accessed 28 February 2008).
-
(2002)
Chromosome
, vol.20
-
-
Dessen, P.1
Knuutila, S.2
Huret, J.L.3
-
11
-
-
0036153173
-
Dissection of HEF1-dependent functions in motility and transcriptional regulation
-
Fashena, S. J., Einarson, M. B., O'Neill, G. M., Patriotis, C. P., and Golemis, E. A. (2002). Dissection of HEF1-dependent functions in motility and transcriptional regulation. J. Cell Sci. 115, 99-111.
-
(2002)
J. Cell Sci
, vol.115
, pp. 99-111
-
-
Fashena, S.J.1
Einarson, M.B.2
O'Neill, G.M.3
Patriotis, C.P.4
Golemis, E.A.5
-
12
-
-
0038049137
-
Tumour-cell invasion and migration: Diversity and escape mechanisms
-
Friedl, P., and Wolf, K. (2003). Tumour-cell invasion and migration: diversity and escape mechanisms. Nat. Rev. Cancer 3, 362-374.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 362-374
-
-
Friedl, P.1
Wolf, K.2
-
13
-
-
0034639283
-
Identification of two focal adhesion targeting sequences in the adapter molecule p130(Cas)
-
Harte, M. T., Macklem, M., Weidow, C. L., Parsons, J. T., and Bouton, A. H. (2000). Identification of two focal adhesion targeting sequences in the adapter molecule p130(Cas). Biochim. Biophys. Acta 1499, 34-48.
-
(2000)
Biochim. Biophys. Acta
, vol.1499
, pp. 34-48
-
-
Harte, M.T.1
Macklem, M.2
Weidow, C.L.3
Parsons, J.T.4
Bouton, A.H.5
-
14
-
-
0029562687
-
-
Ishino, M., Ohba, T., Sasaki, H., and Sasaki, T. (1995). Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which contains a Src homology 3 domain and associates with Fyn. Oncogene 11, 2331-2338.
-
Ishino, M., Ohba, T., Sasaki, H., and Sasaki, T. (1995). Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which contains a Src homology 3 domain and associates with Fyn. Oncogene 11, 2331-2338.
-
-
-
-
15
-
-
0033578684
-
Protein secondary structure prediction based on position-specific scoring matrices
-
Jones, D. T. (1999). Protein secondary structure prediction based on position-specific scoring matrices. J. Mol. Biol. 292, 195-202.
-
(1999)
J. Mol. Biol
, vol.292
, pp. 195-202
-
-
Jones, D.T.1
-
16
-
-
33745288277
-
Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene
-
Kim, M. et al. (2006). Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. Cell 125, 1269-1281.
-
(2006)
Cell
, vol.125
, pp. 1269-1281
-
-
Kim, M.1
-
17
-
-
0032559562
-
CAS/Crk coupling serves as a "molecular switch" for induction of cell migration
-
Klemke, R. L., Leng, J., Molander, R., Brooks, P. C., Vuori, K., and Cheresh, D. A. (1998). CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. J. Cell Biol. 140, 961-972.
-
(1998)
J. Cell Biol
, vol.140
, pp. 961-972
-
-
Klemke, R.L.1
Leng, J.2
Molander, R.3
Brooks, P.C.4
Vuori, K.5
Cheresh, D.A.6
-
18
-
-
0026763128
-
Identification of a set of genes with developmentally down-regulated expression in the mouse brain
-
Kumar, S., Tomooka, Y., and Noda, M. (1992). Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochem. Biophys. Res. Commun. 185, 1155-1161.
-
(1992)
Biochem. Biophys. Res. Commun
, vol.185
, pp. 1155-1161
-
-
Kumar, S.1
Tomooka, Y.2
Noda, M.3
-
19
-
-
0029891787
-
Human Enhancer of Filamentation 1 (HEF1), a novel p130Cas-like docking protein, associates with FAK, and induces pseudohyphal growth in yeast
-
Law, S. F., Estojak, J., Wang, B., Mysliwiec, T., Kruh, G. D., and Golemis, E. A. (1996). Human Enhancer of Filamentation 1 (HEF1), a novel p130Cas-like docking protein, associates with FAK, and induces pseudohyphal growth in yeast. Mol. Cell. Biol. 16, 3327-3337.
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 3327-3337
-
-
Law, S.F.1
Estojak, J.2
Wang, B.3
Mysliwiec, T.4
Kruh, G.D.5
Golemis, E.A.6
-
20
-
-
0033934340
-
The docking protein HEF1 is an apoptotic mediator at focal adhesion sites
-
Law, S. F., O'Neill, G. M., Fashena, S. J., Einarson, M. B., and Golemis, E. A. (2000). The docking protein HEF1 is an apoptotic mediator at focal adhesion sites. Mol. Cell. Biol. 20, 5184-5195.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 5184-5195
-
-
Law, S.F.1
O'Neill, G.M.2
Fashena, S.J.3
Einarson, M.B.4
Golemis, E.A.5
-
21
-
-
0037213715
-
Gene expression and the myth of the average cell
-
Levsky, J. M., and Singer, R. H. (2003). Gene expression and the myth of the average cell. Trends Cell Biol. 13, 4-6.
-
(2003)
Trends Cell Biol
, vol.13
, pp. 4-6
-
-
Levsky, J.M.1
Singer, R.H.2
-
22
-
-
33846092495
-
CellCircuits: A database of protein network models
-
Mak, H. C., Daly, M., Gruebel, B., and Ideker, T. (2007). CellCircuits: a database of protein network models. Nucleic Acids Res. 35, D538-D545.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Mak, H.C.1
Daly, M.2
Gruebel, B.3
Ideker, T.4
-
23
-
-
34249702515
-
Inferring steady state single-cell gene expression distributions from analysis of mesoscopic samples
-
R 119.1-R119.12
-
Mar, J. C., Rubio, R., and Quackenbush, J. (2006). Inferring steady state single-cell gene expression distributions from analysis of mesoscopic samples. Genome Biol. 7, R 119.1-R119.12.
-
(2006)
Genome Biol
, vol.7
-
-
Mar, J.C.1
Rubio, R.2
Quackenbush, J.3
-
24
-
-
0029904694
-
Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta-1 integrin-mediated signaling in lymphocytes
-
Minegishi, M., Tachibana, K., Sato, T., Iwata, S., Nojima, Y., and Morimoto, C. (1996). Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta-1 integrin-mediated signaling in lymphocytes. J. Exp. Med. 184, 1365-1375.
-
(1996)
J. Exp. Med
, vol.184
, pp. 1365-1375
-
-
Minegishi, M.1
Tachibana, K.2
Sato, T.3
Iwata, S.4
Nojima, Y.5
Morimoto, C.6
-
25
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
Minn, A. J., Gupta, G. P., Siegel, P. M., Bos, P. D., Shu, W., Giri, D. D., Viale, A., Olshen, A. B., Gerald, W. L., and Massague, J. (2005). Genes that mediate breast cancer metastasis to lung. Nature 436, 518-524.
-
(2005)
Nature
, vol.436
, pp. 518-524
-
-
Minn, A.J.1
Gupta, G.P.2
Siegel, P.M.3
Bos, P.D.4
Shu, W.5
Giri, D.D.6
Viale, A.7
Olshen, A.B.8
Gerald, W.L.9
Massague, J.10
-
26
-
-
0030611402
-
Requirements for localization of p130Cas to focal adhesions
-
Nakamoto, T., Sakai, R., Honda, H., Ogawa, S., Ueno, H., Suzuki, T., Aizawa, S.-I., Yazaki, Y., and Hirai, H. (1997). Requirements for localization of p130Cas to focal adhesions. Mol. Cell. Biol. 17, 3884-3897.
-
(1997)
Mol. Cell. Biol
, vol.17
, pp. 3884-3897
-
-
Nakamoto, T.1
Sakai, R.2
Honda, H.3
Ogawa, S.4
Ueno, H.5
Suzuki, T.6
Aizawa, S.-I.7
Yazaki, Y.8
Hirai, H.9
-
27
-
-
33645022769
-
HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells
-
Natarajan, M., Stewart, J. E., Golemis, E. A., Pugacheva, E. N., Alexandropoulos, K., Cox, B. D., Wang, W., Grammer, J. R., and Gladson, C. L. (2006). HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells. Oncogene 25, 1721-1732.
-
(2006)
Oncogene
, vol.25
, pp. 1721-1732
-
-
Natarajan, M.1
Stewart, J.E.2
Golemis, E.A.3
Pugacheva, E.N.4
Alexandropoulos, K.5
Cox, B.D.6
Wang, W.7
Grammer, J.R.8
Gladson, C.L.9
-
28
-
-
0034160011
-
Integrin signaling: A new Cas(t) of characters enters the stage
-
O'Neill, G. M., Fashena, S. J., and Golemis, E. A. (2000). Integrin signaling: a new Cas(t) of characters enters the stage. Trends Cell Biol. 10, 111-119.
-
(2000)
Trends Cell Biol
, vol.10
, pp. 111-119
-
-
O'Neill, G.M.1
Fashena, S.J.2
Golemis, E.A.3
-
29
-
-
0034959232
-
Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics
-
O'Neill, G. M., and Golemis, E. A. (2001). Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics. Mol. Cell. Biol. 21, 5094-5108.
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 5094-5108
-
-
O'Neill, G.M.1
Golemis, E.A.2
-
30
-
-
35148825060
-
A new central scaffold for metastasis: Parsing HEF1/Cas-L/NEDD9
-
O'Neill, G. M., Seo, S., Serebriiskii, I. G., Lessin, S. R., and Golemis, E. A. (2007). A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9. Cancer Res. 67, 8975-8979.
-
(2007)
Cancer Res
, vol.67
, pp. 8975-8979
-
-
O'Neill, G.M.1
Seo, S.2
Serebriiskii, I.G.3
Lessin, S.R.4
Golemis, E.A.5
-
31
-
-
4444221565
-
UCSF Chimera - a visualization system for exploratory research and analysis
-
Pettersen, E. F., Goddard, T. D., Huang, C. C., Couch, G. S., Greenblatt, D. M., Meng, E. C., and Ferrin, T. E. (2004). UCSF Chimera - a visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605-1612.
-
(2004)
J. Comput. Chem
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
Goddard, T.D.2
Huang, C.C.3
Couch, G.S.4
Greenblatt, D.M.5
Meng, E.C.6
Ferrin, T.E.7
-
32
-
-
0028889436
-
Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas
-
Polte, T. R., and Hanks, S. K. (1995). Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas. Proc. Natl. Acad. Sci. USA 92, 10678-10682.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 10678-10682
-
-
Polte, T.R.1
Hanks, S.K.2
-
33
-
-
27144495462
-
The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome
-
Pugacheva, E. N., and Golemis, E. A. (2005). The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome. Nat. Cell Biol. 7, 937-946.
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 937-946
-
-
Pugacheva, E.N.1
Golemis, E.A.2
-
34
-
-
0027990414
-
A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner
-
Sakai, R., Iwamatsu, A., Hirano, N., Ogawa, S., Tanaka, T., Mano, H., Yazaki, Y., and Hirai, H. (1994). A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner. EMBO J. 13, 3748-3756.
-
(1994)
EMBO J
, vol.13
, pp. 3748-3756
-
-
Sakai, R.1
Iwamatsu, A.2
Hirano, N.3
Ogawa, S.4
Tanaka, T.5
Mano, H.6
Yazaki, Y.7
Hirai, H.8
-
35
-
-
0036852292
-
Detection of peptides, proteins, and drugs that selectively interact with protein targets
-
Serebriiskii, I. G., Mitina, O., Pugacheva, E., Benevolenskaya, E., Kotova, E., Toby, G. G., Khazak, V., Kaelin, W. G., Chernoff, J., and Golemis, E. A. (2002). Detection of peptides, proteins, and drugs that selectively interact with protein targets. Genome Res. 12, 1785-1791.
-
(2002)
Genome Res
, vol.12
, pp. 1785-1791
-
-
Serebriiskii, I.G.1
Mitina, O.2
Pugacheva, E.3
Benevolenskaya, E.4
Kotova, E.5
Toby, G.G.6
Khazak, V.7
Kaelin, W.G.8
Chernoff, J.9
Golemis, E.A.10
-
36
-
-
34548357152
-
Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle
-
Singh, M., Cowell, L., Seo, S., O'Neill, G., and Golemis, E. (2007). Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle. Cell Biochem. Biophys. 48, 54-72.
-
(2007)
Cell Biochem. Biophys
, vol.48
, pp. 54-72
-
-
Singh, M.1
Cowell, L.2
Seo, S.3
O'Neill, G.4
Golemis, E.5
-
37
-
-
0030669961
-
Tyrosine phosphorylation of crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of crk-associated substrates
-
Tachibana, K., Urano, T., Fujita, H., Ohashi, Y., Kamiguchi, K., Iwata, S., Hirai, H., and Morimoto, C. (1997). Tyrosine phosphorylation of crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of crk-associated substrates. J. Biol. Chem. 272, 29083-29090.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 29083-29090
-
-
Tachibana, K.1
Urano, T.2
Fujita, H.3
Ohashi, Y.4
Kamiguchi, K.5
Iwata, S.6
Hirai, H.7
Morimoto, C.8
-
38
-
-
0034684987
-
Bcar1/p130Cas protein and primary breast cancer: Prognosis and response to tamoxifen treatment
-
van der Flier, S., Brinkman, A., Look, M. P., Kok, E. M., Meijer-Van Gelder, M. E., Klijn, J. G., Dorssers, L. C., and Foekens, J. A. (2000). Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment. J. Natl. Cancer Inst. 92, 120-127.
-
(2000)
J. Natl. Cancer Inst
, vol.92
, pp. 120-127
-
-
van der Flier, S.1
Brinkman, A.2
Look, M.P.3
Kok, E.M.4
Meijer-Van Gelder, M.E.5
Klijn, J.G.6
Dorssers, L.C.7
Foekens, J.A.8
-
39
-
-
0035006726
-
Focal adhesion kinase regulates beta1 integrin dependent migration through an HEF1 effector pathway
-
van Seventer, G. A., Salman, H. J., Law, S. F., O'Neill, G. M., Mullen, M. M., Franz, A. A., Kanner, S. B., Golemis, E. A., and van Seventer, J. M. (2001). Focal adhesion kinase regulates beta1 integrin dependent migration through an HEF1 effector pathway. Eur. J. Immunol. 31, 1417-1427.
-
(2001)
Eur. J. Immunol
, vol.31
, pp. 1417-1427
-
-
van Seventer, G.A.1
Salman, H.J.2
Law, S.F.3
O'Neill, G.M.4
Mullen, M.M.5
Franz, A.A.6
Kanner, S.B.7
Golemis, E.A.8
van Seventer, J.M.9
-
40
-
-
9144233525
-
Database resources of the National Center for Biotechnology Information: Update
-
Wheeler, D. L. et al. (2004). Database resources of the National Center for Biotechnology Information: update. Nucleic Acids Res. 32, D35-40.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Wheeler, D.L.1
-
41
-
-
15244351022
-
The 1.1 A resolution crystal structure of the p130cas SH3 domain and ramifications for ligand selectivity
-
Wisniewska, M., Bossenmaier, B., Georges, G., Hesse, F., Dangl, M., Kunkele, K. P., Ioannidis, I., Huber, R., and Engh, R. A. (2005). The 1.1 A resolution crystal structure of the p130cas SH3 domain and ramifications for ligand selectivity. J. Mol. Biol. 347, 1005-1014.
-
(2005)
J. Mol. Biol
, vol.347
, pp. 1005-1014
-
-
Wisniewska, M.1
Bossenmaier, B.2
Georges, G.3
Hesse, F.4
Dangl, M.5
Kunkele, K.P.6
Ioannidis, I.7
Huber, R.8
Engh, R.A.9
-
42
-
-
0037188507
-
Evaluating conformational free energies: The colony energy and its application to the problem of loop prediction
-
Xiang, Z., Soto, C. S., and Honig, B. (2002). Evaluating conformational free energies: the colony energy and its application to the problem of loop prediction. Proc. Natl. Acad. Sci. USA 99, 7432-7437.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7432-7437
-
-
Xiang, Z.1
Soto, C.S.2
Honig, B.3
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