-
1
-
-
0018821821
-
Factors influencing blood pressure in salt-sensitive patients with hypertension
-
Fujita T, Henry WL, Bartter FC, et al. Factors influencing blood pressure in salt-sensitive patients with hypertension. Am J Med 1980; 69:334-344.
-
(1980)
Am J Med
, vol.69
, pp. 334-344
-
-
Fujita, T.1
Henry, W.L.2
Bartter, F.C.3
-
2
-
-
0024323773
-
The effect of weight loss on the sensitivity of blood pressure to sodium in obese adolescents
-
Rocchini AP, Key J, Bondie D, et al. The effect of weight loss on the sensitivity of blood pressure to sodium in obese adolescents. N Engl J Med 1989; 321:580-585.
-
(1989)
N Engl J Med
, vol.321
, pp. 580-585
-
-
Rocchini, A.P.1
Key, J.2
Bondie, D.3
-
3
-
-
61649119049
-
Metabolic syndrome and salt sensitivity of blood pressure in nondiabetic people in China: A dietary intervention study
-
Chen J, Gu D, Huang J, et al. Metabolic syndrome and salt sensitivity of blood pressure in nondiabetic people in China: a dietary intervention study. Lancet 2009; 373:829-835.
-
(2009)
Lancet
, vol.373
, pp. 829-835
-
-
Chen, J.1
Gu, D.2
Huang, J.3
-
4
-
-
0024576268
-
A genetic polymorphism in the renin gene of Dahl rats cosegregates with blood pressure
-
Rapp JP, Wang SM, Dene H. A genetic polymorphism in the renin gene of Dahl rats cosegregates with blood pressure. Science 1989; 243:542-544.
-
(1989)
Science
, vol.243
, pp. 542-544
-
-
Rapp, J.P.1
Wang, S.M.2
Dene, H.3
-
5
-
-
0026894148
-
Cosegregation of blood pressure with angiotensin converting enzyme and atrial natriuretic peptide receptor genes using Dahl salt-sensitive rats
-
Deng Y, Rapp JP. Cosegregation of blood pressure with angiotensin converting enzyme and atrial natriuretic peptide receptor genes using Dahl salt-sensitive rats. Nat Genet 1992; 1:267-272.
-
(1992)
Nat Genet
, vol.1
, pp. 267-272
-
-
Deng, Y.1
Rapp, J.P.2
-
6
-
-
0027416241
-
Linkage of 11 beta-hydroxylase mutations with altered steroid biosynthesis and blood pressure in the Dahl rat
-
Cicila GT, Rapp JP, Wang JM, et al. Linkage of 11 beta-hydroxylase mutations with altered steroid biosynthesis and blood pressure in the Dahl rat. Nat Genet 1993; 3:346-353.
-
(1993)
Nat Genet
, vol.3
, pp. 346-353
-
-
Cicila, G.T.1
Rapp, J.P.2
Wang, J.M.3
-
7
-
-
0028233482
-
Genetic mapping of two new blood pressure quantitative trait loci in the rat by genotyping endothelin system genes
-
Deng AY, Dene H, Pravenec M, Rapp JP. Genetic mapping of two new blood pressure quantitative trait loci in the rat by genotyping endothelin system genes. J Clin Invest 1994; 93:2701-2709.
-
(1994)
J Clin Invest
, vol.93
, pp. 2701-2709
-
-
Deng, A.Y.1
Dene, H.2
Pravenec, M.3
Rapp, J.P.4
-
8
-
-
0027996820
-
Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet
-
Makita K, Takahashi K, Karara A, et al. Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet. J Clin Invest 1994; 94:2414-2420.
-
(1994)
J Clin Invest
, vol.94
, pp. 2414-2420
-
-
Makita, K.1
Takahashi, K.2
Karara, A.3
-
9
-
-
0028960475
-
Locus for the inducible, but not a constitutive, nitric oxide synthase cosegregates with blood pressure in the Dahl salt-sensitive rat
-
Deng AY, Rapp JP. Locus for the inducible, but not a constitutive, nitric oxide synthase cosegregates with blood pressure in the Dahl salt-sensitive rat. J Clin Invest 1995; 95:2170-2177.
-
(1995)
J Clin Invest
, vol.95
, pp. 2170-2177
-
-
Deng, A.Y.1
Rapp, J.P.2
-
10
-
-
0030063846
-
Genetic mapping of two blood pressure quantitative trait loci on rat chromosome 1
-
Gu L, Dene H, Deng AY, et al. Genetic mapping of two blood pressure quantitative trait loci on rat chromosome 1. J Clin Invest 1996; 97:777-788.
-
(1996)
J Clin Invest
, vol.97
, pp. 777-788
-
-
Gu, L.1
Dene, H.2
Deng, A.Y.3
-
11
-
-
0032529929
-
The alpha1 Na,K-ATPase gene is a susceptibility hypertension gene in the Dahl salt-sensitive HSD rat
-
Herrera VL, Xie HX, Lopez LV, et al. The alpha1 Na,K-ATPase gene is a susceptibility hypertension gene in the Dahl salt-sensitive HSD rat. J Clin Invest 1998; 102:1102-1111.
-
(1998)
J Clin Invest
, vol.102
, pp. 1102-1111
-
-
Herrera, V.L.1
Xie, H.X.2
Lopez, L.V.3
-
12
-
-
0030842485
-
Role of natriuretic peptide receptor type C in Dahl salt-sensitive hypertensive rats
-
Nagase M, Ando K, Katafuchi T, et al. Role of natriuretic peptide receptor type C in Dahl salt-sensitive hypertensive rats. Hypertension 1997; 30:177-183.
-
(1997)
Hypertension
, vol.30
, pp. 177-183
-
-
Nagase, M.1
Ando, K.2
Katafuchi, T.3
-
13
-
-
0033770680
-
Expression of LOX-1, an oxidized lowdensity lipoprotein receptor, in experimental hypertensive glomerulosclerosis
-
Nagase M, Kaname S, Nagase T, et al. Expression of LOX-1, an oxidized lowdensity lipoprotein receptor, in experimental hypertensive glomerulosclerosis. J Am Soc Nephrol 2000; 11:1826-1836.
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 1826-1836
-
-
Nagase, M.1
Kaname, S.2
Nagase, T.3
-
14
-
-
0033029461
-
Retrotransposons transcribed preferentially in proximal tubules of salt-hypertensive rats
-
Nagase M, Kato A, Ono T, et al. Retrotransposons transcribed preferentially in proximal tubules of salt-hypertensive rats. Kidney Int 1999; 55:995-1004.
-
(1999)
Kidney Int
, vol.55
, pp. 995-1004
-
-
Nagase, M.1
Kato, A.2
Ono, T.3
-
15
-
-
79951506090
-
K\+ channel mutations in adrenal aldosteroneproducing adenomas and hereditary hypertension
-
Choi M, Scholl UI, Yue P, et al. K\+ channel mutations in adrenal aldosteroneproducing adenomas and hereditary hypertension. Science 2011; 331:768-772.
-
(2011)
Science
, vol.331
, pp. 768-772
-
-
Choi, M.1
Scholl, U.I.2
Yue, P.3
-
16
-
-
3042731163
-
Serum aldosterone and the incidence of hypertension in nonhypertensive persons
-
Vasan RS, Evans JC, Larson MG, et al. Serum aldosterone and the incidence of hypertension in nonhypertensive persons. N Engl J Med 2004; 351:33-41.
-
(2004)
N Engl J Med
, vol.351
, pp. 33-41
-
-
Vasan, R.S.1
Evans, J.C.2
Larson, M.G.3
-
17
-
-
37349001285
-
Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase
-
Makhanova N, Hagaman J, Kim HS, Smithies O. Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase. Hypertension 2008; 51:134-140.
-
(2008)
Hypertension
, vol.51
, pp. 134-140
-
-
Makhanova, N.1
Hagaman, J.2
Kim, H.S.3
Smithies, O.4
-
18
-
-
73849110168
-
Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6
-
Doi M, Takahashi Y, Komatsu R, et al. Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6. Nat Med 2010; 16:67-74.
-
(2010)
Nat Med
, vol.16
, pp. 67-74
-
-
Doi, M.1
Takahashi, Y.2
Komatsu, R.3
-
19
-
-
77954434421
-
The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure
-
Nguyen Dinh Cat A, Griol-Charhbili V, Loufrani L, et al. The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure. FASEB J 2010; 24:2454-2463.
-
(2010)
FASEB J
, vol.24
, pp. 2454-2463
-
-
Nguyen Dinh Cat, A.1
Griol-Charhbili, V.2
Loufrani, L.3
-
20
-
-
84868662652
-
Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors
-
McCurley A, Pires PW, Bender SB, et al. Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors. Nat Med 2012; 18:1429-1433.
-
(2012)
Nat Med
, vol.18
, pp. 1429-1433
-
-
McCurley, A.1
Pires, P.W.2
Bender, S.B.3
-
21
-
-
79956193591
-
Mineralocorticoid actions in the brain and hypertension
-
Huang BS, Leenen FH. Mineralocorticoid actions in the brain and hypertension. Curr Hypertens Rep 2011; 13:214-220.
-
(2011)
Curr Hypertens Rep
, vol.13
, pp. 214-220
-
-
Huang, B.S.1
Leenen, F.H.2
-
22
-
-
33744981628
-
Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker
-
Nagase M, Shibata S, Yoshida S, et al. Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker. Hypertension 2006; 47:1084-1093.
-
(2006)
Hypertension
, vol.47
, pp. 1084-1093
-
-
Nagase, M.1
Shibata, S.2
Yoshida, S.3
-
23
-
-
35848952953
-
Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: Role of oxidative stress
-
Nagase M, Matsui H, Shibata S, et al. Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: role of oxidative stress. Hypertension 2007; 50:877-883.
-
(2007)
Hypertension
, vol.50
, pp. 877-883
-
-
Nagase, M.1
Matsui, H.2
Shibata, S.3
-
24
-
-
57349168398
-
Modification of mineralocorticoid receptor function by Rac1 GTPase: Implication in proteinuric kidney disease
-
Shibata S, Nagase M, Yoshida S, et al. Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease. Nat Med 2008; 14:1370-1376.
-
(2008)
Nat Med
, vol.14
, pp. 1370-1376
-
-
Shibata, S.1
Nagase, M.2
Yoshida, S.3
-
25
-
-
79960972766
-
Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptordependent pathway
-
Shibata S, Mu S, Kawarazaki H, et al. Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptordependent pathway. J Clin Invest 2011; 121:3233-3243.
-
(2011)
J Clin Invest
, vol.121
, pp. 3233-3243
-
-
Shibata, S.1
Mu, S.2
Kawarazaki, H.3
-
26
-
-
84861832781
-
Angiotensin II-and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation
-
Kawarazaki W, Nagase M, Yoshida S, et al. Angiotensin II-and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation. J Am Soc Nephrol 2012; 23:997-1007.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 997-1007
-
-
Kawarazaki, W.1
Nagase, M.2
Yoshida, S.3
-
28
-
-
50149083752
-
Mammalian Rho GTPases new insights into their functions from in vivo studies
-
Heasman SJ, Ridley AJ. Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol 2008; 9:690-701.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
29
-
-
1542406446
-
NOX enzymes and the biology of reactive oxygen
-
Lambeth JD. NOX enzymes and the biology of reactive oxygen. Nat Rev Immunol 2004; 4:181-189.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 181-189
-
-
Lambeth, J.D.1
-
30
-
-
13444252631
-
GEF means go: Turning on RHO GTPases with guanine nucleotide-exchange factors
-
Rossman KL, Der CJ, Sondek J. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol 2005; 6:167-180.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 167-180
-
-
Rossman, K.L.1
Der, C.J.2
Sondek, J.3
-
31
-
-
34249018367
-
GEFs and GAPs: Critical elements in the control of small G proteins
-
Bos JL, Rehmann H, Wittinghofer A. GEFs and GAPs: critical elements in the control of small G proteins. Cell 2007; 129:865-877.
-
(2007)
Cell
, vol.129
, pp. 865-877
-
-
Bos, J.L.1
Rehmann, H.2
Wittinghofer, A.3
-
32
-
-
77949541746
-
Proteinuria: An enzymatic disease of the podocyte?
-
Mundel P, Reiser J. Proteinuria: an enzymatic disease of the podocyte? Kidney Int 2010; 77:571-580.
-
(2010)
Kidney Int
, vol.77
, pp. 571-580
-
-
Mundel, P.1
Reiser, J.2
-
33
-
-
78049524253
-
Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels
-
Tian D, Jacobo SM, Billing D, et al. Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels. Sci Signal 2010; 3:ra77.
-
(2010)
Sci Signal
, vol.3
-
-
Tian, D.1
Jacobo, S.M.2
Billing, D.3
-
34
-
-
38049032013
-
Modification of kidney barrier function by the urokinase receptor
-
Wei C, Moeller CC, Altintas MM, et al. Modification of kidney barrier function by the urokinase receptor. Nat Med 2008; 14:55-63.
-
(2008)
Nat Med
, vol.14
, pp. 55-63
-
-
Wei, C.1
Moeller, C.C.2
Altintas, M.M.3
-
35
-
-
43749116673
-
HIV-1 Nef disrupts the podocyte actin cytoskeleton by interacting with diaphanous interacting protein
-
Lu TC, He JC, Wang ZH, et al. HIV-1 Nef disrupts the podocyte actin cytoskeleton by interacting with diaphanous interacting protein. J Biol Chem 2008; 283:8173-8182.
-
(2008)
J Biol Chem
, vol.283
, pp. 8173-8182
-
-
Lu, T.C.1
He, J.C.2
Zh, W.3
-
36
-
-
80053410497
-
Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis
-
Akilesh S, Suleiman H, Yu H, et al. Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis. J Clin Invest 2011; 121:4127-4137.
-
(2011)
J Clin Invest
, vol.121
, pp. 4127-4137
-
-
Akilesh, S.1
Suleiman, H.2
Yu, H.3
-
37
-
-
0034120364
-
Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1
-
Sussman MA, Welch S, Walker A, et al. Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1. J Clin Invest 2000; 105:875-886.
-
(2000)
J Clin Invest
, vol.105
, pp. 875-886
-
-
Sussman, M.A.1
Welch, S.2
Walker, A.3
-
38
-
-
34447521792
-
Role of Rac1 GTPase activation in atrial fibrillation
-
Adam O, Frost G, Custodis F, et al. Role of Rac1 GTPase activation in atrial fibrillation. J Am Coll Cardiol 2007; 50:359-367.
-
(2007)
J Am Coll Cardiol
, vol.50
, pp. 359-367
-
-
Adam, O.1
Frost, G.2
Custodis, F.3
-
39
-
-
33646591530
-
Requirement of Rac1 in the development of cardiac hypertrophy
-
Satoh M,Ogita H, Takeshita K, et al. Requirement of Rac1 in the development of cardiac hypertrophy. Proc Natl Acad Sci USA 2006; 103:7432-7437.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7432-7437
-
-
Satoh, M.1
Ogita, H.2
Takeshita, K.3
-
40
-
-
67649118398
-
Rac1 is required for cardiomyocyte apoptosis during hyperglycemia
-
Shen E, Li Y, Shan L, et al. Rac1 is required for cardiomyocyte apoptosis during hyperglycemia. Diabetes 2009; 58:2386-2395.
-
(2009)
Diabetes
, vol.58
, pp. 2386-2395
-
-
Shen, E.1
Li, Y.2
Shan, L.3
-
41
-
-
66149111387
-
Rac1 is a critical mediator of endothelium-derived neurotrophic activity
-
Sawada N, Kim HH, Moskowitz MA, Liao JK. Rac1 is a critical mediator of endothelium-derived neurotrophic activity. Sci Signal 2009; 2:ra10.
-
(2009)
Sci Signal
, vol.2
-
-
Sawada, N.1
Kim, H.H.2
Moskowitz, M.A.3
Liao, J.K.4
-
42
-
-
0141816676
-
Inactivation of the small GTPase Rac1 protects the liver from ischemia/reperfusion injury in the rat
-
Harada N, Iimuro Y, Nitta T, et al. Inactivation of the small GTPase Rac1 protects the liver from ischemia/reperfusion injury in the rat. Surgery 2003; 134:480-491.
-
(2003)
Surgery
, vol.134
, pp. 480-491
-
-
Harada, N.1
Iimuro, Y.2
Nitta, T.3
-
43
-
-
33644853221
-
Selective Rac-1 inhibition protects from diabetes-induced vascular injury
-
Vecchione C, Aretini A, Marino G, et al. Selective Rac-1 inhibition protects from diabetes-induced vascular injury. Circ Res 2006; 98:218-225.
-
(2006)
Circ Res
, vol.98
, pp. 218-225
-
-
Vecchione, C.1
Aretini, A.2
Marino, G.3
-
44
-
-
27844581709
-
RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo
-
Desire L, Bourdin J, Loiseau N, et al. RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo. J Biol Chem 2005; 280:37516-37525.
-
(2005)
J Biol Chem
, vol.280
, pp. 37516-37525
-
-
Desire, L.1
Bourdin, J.2
Loiseau, N.3
-
45
-
-
84859768464
-
Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase
-
Montalvo-Ortiz BL, Castillo-Pichardo L, Hernandez E, et al. Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase. J Biol Chem 2012; 287:13228-13238.
-
(2012)
J Biol Chem
, vol.287
, pp. 13228-13238
-
-
Montalvo-Ortiz, B.L.1
Castillo-Pichardo, L.2
Hernandez, E.3
-
46
-
-
78049274198
-
The role of Rho protein signaling in hypertension
-
Loirand G, Pacaud P. The role of Rho protein signaling in hypertension. Nat Rev Cardiol 2010; 7:637-647.
-
(2010)
Nat Rev Cardiol
, vol.7
, pp. 637-647
-
-
Loirand, G.1
Pacaud, P.2
-
48
-
-
50949086778
-
Regulation of endothelial nitric oxide synthase and postnatal angiogenesis by Rac1
-
Sawada N, Salomone S, Kim HH, et al. Regulation of endothelial nitric oxide synthase and postnatal angiogenesis by Rac1. Circ Res 2008; 103:360-368.
-
(2008)
Circ Res
, vol.103
, pp. 360-368
-
-
Sawada, N.1
Salomone, S.2
Kim, H.H.3
-
49
-
-
4444336724
-
Requirement for Rac1-dependent NADPH oxidase in the cardiovascular and dipsogenic actions of angiotensin II in the brain
-
Zimmerman MC, Dunlay RP, Lazartigues E, et al. Requirement for Rac1-dependent NADPH oxidase in the cardiovascular and dipsogenic actions of angiotensin II in the brain. Circ Res 2004; 95:532-539.
-
(2004)
Circ Res
, vol.95
, pp. 532-539
-
-
Zimmerman, M.C.1
Dunlay, R.P.2
Lazartigues, E.3
-
50
-
-
34250828562
-
Inhibition of Rac1-derived reactive oxygen species in nucleus tractus solitarius decreases blood pressure and heart rate in stroke-prone spontaneously hypertensive rats
-
Nozoe M, Hirooka Y, Koga Y, et al. Inhibition of Rac1-derived reactive oxygen species in nucleus tractus solitarius decreases blood pressure and heart rate in stroke-prone spontaneously hypertensive rats. Hypertension 2007; 50:62-68.
-
(2007)
Hypertension
, vol.50
, pp. 62-68
-
-
Nozoe, M.1
Hirooka, Y.2
Koga, Y.3
-
51
-
-
74949139625
-
The Rho/Rac exchange factor Vav2 controls nitric oxide-dependent responses in mouse vascular smooth muscle cells
-
Sauzeau V, Sevilla MA, Montero MJ, Bustelo XR. The Rho/Rac exchange factor Vav2 controls nitric oxide-dependent responses in mouse vascular smooth muscle cells. J Clin Invest 2010; 120:315-330.
-
(2010)
J Clin Invest
, vol.120
, pp. 315-330
-
-
Sauzeau, V.1
Sevilla, M.A.2
Montero, M.J.3
Bustelo, X.R.4
-
52
-
-
33745929899
-
Vav3 proto-oncogene deficiency leads to sympathetic hyperactivity and cardiovascular dysfunction
-
Sauzeau V, Sevilla MA, Rivas-Elena JV, et al. Vav3 proto-oncogene deficiency leads to sympathetic hyperactivity and cardiovascular dysfunction. Nat Med 2006; 12:841-845.
-
(2006)
Nat Med
, vol.12
, pp. 841-845
-
-
Sauzeau, V.1
Sevilla, M.A.2
Rivas-Elena, J.V.3
-
53
-
-
76249134110
-
The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure
-
Guilluy C, Bregeon J, Toumaniantz G, et al. The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure. Nat Med 2010; 16:183-190.
-
(2010)
Nat Med
, vol.16
, pp. 183-190
-
-
Guilluy, C.1
Bregeon, J.2
Toumaniantz, G.3
-
54
-
-
38049017120
-
G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension
-
Wirth A, Benyo Z, Lukasova M, et al. G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension. Nat Med 2008; 14:64-68.
-
(2008)
Nat Med
, vol.14
, pp. 64-68
-
-
Wirth, A.1
Benyo, Z.2
Lukasova, M.3
-
55
-
-
0037121966
-
Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression
-
Tzima E, Del Pozo MA, Kiosses WB, et al. Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression. EMBO J 2002; 21:6791-6800.
-
(2002)
EMBO J
, vol.21
, pp. 6791-6800
-
-
Tzima, E.1
Del Pozo, M.A.2
Kiosses, W.B.3
-
56
-
-
33845686162
-
Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors
-
Kawashima T, Bao YC, Nomura Y, et al. Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors. J Cell Biol 2006; 175:937-946.
-
(2006)
J Cell Biol
, vol.175
, pp. 937-946
-
-
Kawashima, T.1
Bao, Y.C.2
Nomura, Y.3
-
57
-
-
41949105179
-
Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling
-
Wu X, Tu X, Joeng KS, et al. Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling. Cell 2008; 133:340-353.
-
(2008)
Cell
, vol.133
, pp. 340-353
-
-
Wu, X.1
Tu, X.2
Joeng, K.S.3
-
58
-
-
0015951071
-
Genetic influence of the kidneys on blood pressure Evidence from chronic renal homografts in rats with opposite predispositions to hypertension
-
Dahl LK, Heine M, Thompson K. Genetic influence of the kidneys on blood pressure. Evidence from chronic renal homografts in rats with opposite predispositions to hypertension. Circ Res 1974; 40:94-101.
-
(1974)
Circ Res
, vol.40
, pp. 94-101
-
-
Dahl, L.K.1
Heine, M.2
Thompson, K.3
-
59
-
-
0025817650
-
Blood pressure control-special role of the kidneys and body fluids
-
Guyton AC. Blood pressure control-special role of the kidneys and body fluids. Science 1991; 252:1813-1816.
-
(1991)
Science
, vol.252
, pp. 1813-1816
-
-
Guyton, A.C.1
-
60
-
-
0014497112
-
Effects of adrenalectomy on blood pressure in salt-fed, hypertension-prone rats. Failure of hypertension to develop in absence of evidence of adrenal cortical tissue
-
Iwai J, Knudsen KD, Dahl LK, Tassinari L. Effects of adrenalectomy on blood pressure in salt-fed, hypertension-prone rats. Failure of hypertension to develop in absence of evidence of adrenal cortical tissue. J Exp Med 1969; 129:663-678.
-
(1969)
J Exp Med
, vol.129
, pp. 663-678
-
-
Iwai, J.1
Knudsen, K.D.2
Dahl, L.K.3
Tassinari, L.4
-
61
-
-
0037386904
-
Dietary salt regulates renal SGK1 abundance: Relevance to salt sensitivity in the Dahl rat
-
Farjah M, Roxas BP, Geenen DL, Danziger RS. Dietary salt regulates renal SGK1 abundance: relevance to salt sensitivity in the Dahl rat. Hypertension 2003; 41:874-878.
-
(2003)
Hypertension
, vol.41
, pp. 874-878
-
-
Farjah, M.1
Roxas, B.P.2
Geenen, D.L.3
Danziger, R.S.4
-
62
-
-
34447092318
-
Abnormal expression of ENaC and SGK1 mRNA induced by dietary sodium in Dahl salt-sensitively hypertensive rats
-
Aoi W, Niisato N, Sawabe Y, et al. Abnormal expression of ENaC and SGK1 mRNA induced by dietary sodium in Dahl salt-sensitively hypertensive rats. Cell Biol Int 2007; 31:1288-1291.
-
(2007)
Cell Biol Int
, vol.31
, pp. 1288-1291
-
-
Aoi, W.1
Niisato, N.2
Sawabe, Y.3
-
63
-
-
84865790123
-
Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury
-
Luther JM, Luo P, Wang Z, et al. Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury. Kidney Int 2012; 82:643-651.
-
(2012)
Kidney Int
, vol.82
, pp. 643-651
-
-
Luther, J.M.1
Luo, P.2
Wang, Z.3
-
64
-
-
77956388193
-
Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice
-
Usher MG, Duan SZ, Ivaschenko CY, et al. Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice. J Clin Invest 2010; 120:3350-3364.
-
(2010)
J Clin Invest
, vol.120
, pp. 3350-3364
-
-
Usher, M.G.1
Duan, S.Z.2
Ivaschenko, C.Y.3
-
65
-
-
16444375794
-
Angiotensin II and aldosterone regulate gene transcription via functional mineralocorticoid receptors in human coronary artery smooth muscle cells
-
Jaffe IZ, Mendelsohn ME. Angiotensin II and aldosterone regulate gene transcription via functional mineralocorticoid receptors in human coronary artery smooth muscle cells. Circ Res 2005; 96:643-650.
-
(2005)
Circ Res
, vol.96
, pp. 643-650
-
-
Jaffe, I.Z.1
Mendelsohn, M.E.2
-
66
-
-
24944582139
-
Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts
-
Friis MB, Friborg CR, Schneider L, et al. Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts. J Physiol 2005; 567:427-443.
-
(2005)
J Physiol
, vol.567
, pp. 427-443
-
-
Friis, M.B.1
Friborg, C.R.2
Schneider, L.3
-
67
-
-
0344668554
-
Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock
-
Uhlik MT, Abell AN, Johnson NL, et al. Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock. Nat Cell Biol 2003; 5:1104-1110.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 1104-1110
-
-
Uhlik, M.T.1
Abell, A.N.2
Johnson, N.L.3
-
68
-
-
79955480132
-
Novel role of Rac1/WAVE signaling mechanism in regulation of the epithelial Na\+ channel
-
Karpushev AV, Levchenko V, Ilatovskaya DV, et al. Novel role of Rac1/WAVE signaling mechanism in regulation of the epithelial Na\+ channel. Hypertension 2011; 57:996-1002.
-
(2011)
Hypertension
, vol.57
, pp. 996-1002
-
-
Karpushev, A.V.1
Levchenko, V.2
Ilatovskaya, D.V.3
-
69
-
-
77950332094
-
Rac1-mediated NADPH oxidase release of O2-regulates epithelial sodium channel activity in the alveolar epithelium
-
Takemura Y, Goodson P, Bao HF, et al. Rac1-mediated NADPH oxidase release of O2-regulates epithelial sodium channel activity in the alveolar epithelium. Am J Physiol Lung Cell Mol Physiol 2010; 298:L509-L520.
-
(2010)
Am J Physiol Lung Cell Mol Physiol
, vol.298
-
-
Takemura, Y.1
Goodson, P.2
Bao, H.F.3
-
70
-
-
75149166127
-
Rac1 mediates NaCl-induced superoxide generation in the thick ascending limb
-
Silva GB, Garvin JL. Rac1 mediates NaCl-induced superoxide generation in the thick ascending limb. Am J Physiol Renal Physiol 2010; 298:F421-F425.
-
(2010)
Am J Physiol Renal Physiol
, vol.298
-
-
Silva, G.B.1
Garvin, J.L.2
-
71
-
-
0344873104
-
Renal and vascular oxidative stress and salt-sensitivity of arterial pressure
-
Manning RD Jr, Meng S, Tian N. Renal and vascular oxidative stress and salt-sensitivity of arterial pressure. Acta Physiol Scand 2003; 179:243-250.
-
(2003)
Acta Physiol Scand
, vol.179
, pp. 243-250
-
-
Manning Jr., R.D.1
Meng, S.2
Tian, N.3
-
72
-
-
0036088542
-
Production of superoxide through NADH oxidase in thick ascending limb of Henle's loop in rat kidney
-
Li N, Yi FX, Spurrier JL, et al. Production of superoxide through NADH oxidase in thick ascending limb of Henle's loop in rat kidney. Am J Physiol Renal Physiol 2002; 282:F1111-F1119.
-
(2002)
Am J Physiol Renal Physiol
, vol.282
-
-
Li, N.1
Yi, F.X.2
Spurrier, J.L.3
-
74
-
-
0025474018
-
Greater loop chloride uptake contributes to blunted pressure natriuresis in Dahl salt sensitive rats
-
Kirchner KA. Greater loop chloride uptake contributes to blunted pressure natriuresis in Dahl salt sensitive rats. J Am Soc Nephrol 1990; 1:180-186.
-
(1990)
J Am Soc Nephrol
, vol.1
, pp. 180-186
-
-
Kirchner, K.A.1
-
75
-
-
75449088045
-
GTPase-Rac enhances depolarization-induced superoxide production by the macula densa during tubuloglomerular feedback
-
Liu R, Juncos LA. GTPase-Rac enhances depolarization-induced superoxide production by the macula densa during tubuloglomerular feedback. Am J Physiol Regul Integr Comp Physiol 2010; 298:R453-R458.
-
(2010)
Am J Physiol Regul Integr Comp Physiol
, vol.298
-
-
Liu, R.1
Juncos, L.A.2
-
76
-
-
61749089305
-
Isoforms and functions of NAD(P)H oxidase at the macula densa
-
Zhang R, Harding P, Garvin JL, et al. Isoforms and functions of NAD(P)H oxidase at the macula densa. Hypertension 2009; 53:556-563.
-
(2009)
Hypertension
, vol.53
, pp. 556-563
-
-
Zhang, R.1
Harding, P.2
Garvin, J.L.3
-
77
-
-
84857634292
-
Aldosterone blunts tubuloglomerular feedback by activating macula densa mineralocorticoid receptors
-
Fu Y, Hall JE, Lu D, et al. Aldosterone blunts tubuloglomerular feedback by activating macula densa mineralocorticoid receptors. Hypertension 2012; 59:599-606.
-
(2012)
Hypertension
, vol.59
, pp. 599-606
-
-
Fu, Y.1
Hall, J.E.2
Lu, D.3
-
78
-
-
77952875835
-
Renal infiltration of immunocompetent cells: Cause and effect of sodium-sensitive hypertension
-
Rodriguez-Iturbe B. Renal infiltration of immunocompetent cells: cause and effect of sodium-sensitive hypertension. Clin Exp Nephrol 2010; 14:105-111.
-
(2010)
Clin Exp Nephrol
, vol.14
, pp. 105-111
-
-
Rodriguez-Iturbe, B.1
-
79
-
-
66749106368
-
Macrophages regulate saltdependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism
-
Machnik A, Neuhofer W, Jantsch J, et al. Macrophages regulate saltdependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat Med 2009; 15:545-552.
-
(2009)
Nat Med
, vol.15
, pp. 545-552
-
-
MacHnik, A.1
Neuhofer, W.2
Jantsch, J.3
-
80
-
-
0035839437
-
Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B
-
Sanlioglu S, Williams CM, Samavati L, et al. Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B. J Biol Chem 2001; 276:30188-30198.
-
(2001)
J Biol Chem
, vol.276
, pp. 30188-30198
-
-
Sanlioglu, S.1
Williams, C.M.2
Samavati, L.3
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