Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression

EMBO Journal

Volumn 21, Issue 24, 2002, Pages 6791-6800

  Tzima, Eleni ^a   Del Pozo, Miguel Angel ^a   Kiosses, William B ^a   Mohamed, Samih A ^a   Li, Song ^b   Chien, Shu ^c   Schwartz, Martin Alexander ^d  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b University of California   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Cytoskeleton; Fluid shear stress; Mechanotransduction; NF B; Rac GTPase

Indexed keywords

GUANOSINE TRIPHOSPHATASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; RAC1 PROTEIN;

ARTICLE; ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; CYTOSKELETON; ENDOTHELIUM CELL; ENERGY TRANSFER; EXTRACELLULAR MATRIX; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION; HEMODYNAMICS; INFLAMMATION; LEUKOCYTE ADHERENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; SHEAR STRESS;

ANIMALS; CATTLE; CELL ADHESION; CELLS, CULTURED; CYTOSKELETON; DIMERIZATION; ENERGY TRANSFER; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENES, DOMINANT; GREEN FLUORESCENT PROTEINS; GTP PHOSPHOHYDROLASES; INTERCELLULAR ADHESION MOLECULE-1; LEUKOCYTES; LUCIFERASES; LUMINESCENT PROTEINS; MICROSCOPY, FLUORESCENCE; NF-KAPPA B; PLASMIDS; PROTEIN TRANSPORT; RAC GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN; SPECTROMETRY, FLUORESCENCE; STRESS, MECHANICAL; TIME FACTORS; TRANSFECTION;

EUKARYOTA;

EID: 0037121966     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf688     Document Type: Article

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