HIV-1 Nef disrupts the podocyte actin cytoskeleton by interacting with diaphanous interacting protein

Journal of Biological Chemistry

Volumn 283, Issue 13, 2008, Pages 8173-8182

  Lu, Ting Chi ^a   He, John Cijiang ^a,b   Wang, Zhao Hui ^a,c   Feng, Xiaobei ^a,c   Fukumi Tominaga, Tomoko ^d   Chen, Nan ^c   Xu, Jin ^a   Iyengar, Ravi ^a   Klotman, Paul E ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FLOW INTERACTIONS; PHOSPHORYLATION; PRESSURE EFFECTS;

ACTIN CYTOSKELETON; BASE-LINES; BINDING DOMAINS; CYTOSKELETON; DOMINANT NEGATIVES; HOST CELLS; HUMAN IMMUNODEFICIENCY VIRUSES; INDUCED LOSSES; LAMELLIPODIA; MORPHOLOGICAL CHANGES; NEPHROPATHY; PATHOLOGICAL CHANGES; PODOCYTES; SIGNALING PATHWAYS; SRC HOMOLOGY 3; SRC KINASES; STRESS FIBER FORMATIONS; STRESS FIBERS; VIRAL REPLICATIONS;

CHEMICAL REACTIONS;

ACTIN; DIAPHANOUS INTERACTING PROTEIN; NEF PROTEIN; PROTEIN; PROTEIN P190; PROTEIN TYROSINE KINASE; RAC PROTEIN; RHO FACTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; MUSCLE PROTEIN; NCKIPSD PROTEIN, MOUSE; NEF PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; VAV PROTEIN; VAV2 PROTEIN, MOUSE;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOWN REGULATION; HUMAN IMMUNODEFICIENCY VIRUS 1; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; STRESS FIBER; ANIMAL; CYTOSKELETON; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ACTINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CYTOSKELETON; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HIV-1; MICE; MUSCLE PROTEINS; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; PHOSPHORYLATION; PODOCYTES; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-VAV; RAC1 GTP-BINDING PROTEIN; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 43749116673     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708920200     Document Type: Article

References (47)

1. Deacon, N. J., Tsykin, A., Solomon, A., Smith, K., Ludford-Menting, M., Hooker, D. J., McPhee, D. A., Greenway, A. L., Ellett, A., Chatfield, C., Lawson, V. A., Crowe, S., Maerz, A., Sonza, S., Learmont, J., Sullivan, J. S., Cunningham, A., Dwyer, D., Dowton, D., and Mills, J. (1995) Science 270, 988-991
2. Hanna, Z., Kay, D. G., Rebai, N., Guimond, A., Jothy, S., and Jolicoeur, P. (1998) Cell 95, 163-175
3. Kestler, H. W., III, Ringler, D. J., Mori, K., Panicali, D. L., Sehgal, P. K., Daniel, M. D., and Desrosiers, R. C. (1991) Cell 65, 651-662
4. Kirchhoff, F., Greenough, T. C., Brettler, D. B., Sullivan, J. L., and Desrosiers, R. C. (1995) N. Engl. J. Med. 332, 228-232
5. Fackler, O. T., and Baur, A. S. (2002) Immunity 16, 493-497
6. Campbell, E. M., Nunez, R., and Hope, T. J. (2004) J. Virol. 78, 5745-5755
7. Haller, C., Rauch, S., Michel, N., Hannemann, S., Lehmann, M. J., Keppler, O. T., and Fackler, O. T. (2006) J. Biol. Chem. 281, 19618-19630
8. Fackler, O. T., Kienzle, N., Kremmer, E., Boese, A., Schramm, B., Klimkait, T., Kucherer, C., and Mueller-Lantzsch, N. (1997) Eur. J. Biochem. 247, 843-851
9. Quaranta, M. G., Mattioli, B., Spadaro, F., Straface, E., Giordani, L., Ramoni, C., Malorni, W., and Viora, M. (2003) FASEB J. 17, 2025-2036
10. Geyer, M., Fackler, O. T., and Peterlin, B. M. (2001) EMBO Rep. 2, 580-585
11. Lee, C. H., Saksela, K., Mirza, U. A., Chait, B. T., and Kuriyan, J. (1996) Cell 85, 931-942
12. Renkema, G. H., Manninen, A., Mann, D. A., Harris, M., and Saksela, K. (1999) Curr. Biol. 9, 1407-1410
13. Kaminchik, J., Margalit, R., Yaish, S., Drummer, H., Amit, B., Sarver, N., Gorecki, M., and Panet, A. (1994) AIDS Res. Hum. Retroviruses 10, 1003-1010
14. Rao, T. K., Friedman, E. A., and Nicastri, A. D. (1987) N. Engl. J. Med. 316, 1062-1068
15. D'Agati, V., Suh, J. I., Carbone, L., Cheng, J. T., and Appel, G. (1989) Kidney Int. 35, 1358-1370
16. Chander, P., Soni, A., Suri, A., Bhagwat, R., Yoo, J., and Treser, G. (1987) Am. J. Pathol. 126, 513-526
17. Barisoni, L., Kriz, W., Mundel, P., and D'Agati, V. (1999) J. Am. Soc. Nephrol. 10, 51-61
18. Winston, J. A., Bruggeman, L. A., Ross, M. D., Jacobson, J., Ross, L., D'Agati, V. D., Klotman, P. E., and Klotman, M. E. (2001) N. Engl. J. Med. 344, 1979-1984
19. Zhong, J., Zuo, Y., Ma, J., Fogo, A. B., Jolicoeur, P., Ichikawa, I., and Matsusaka, T. (2005) Kidney Int. 68, 1048-1060
20. Husain, M., Gusella, G. L., Klotman, M. E., Gelman, I. H., Ross, M. D., Schwartz, E. J., Cara, A., and Klotman, P. E. (2002) J. Am. Soc. Nephrol. 13, 1806-1815
21. Sunamoto, M., Husain, M., He, J. C., Schwartz, E. J., and Klotman, P. E. (2003) Kidney Int. 64, 1695-1701
22. He, J. C., Husain, M., Sunamoto, M., D'Agati, V. D., Klotman, M. E., Iyengar, R., and Klotman, P. E. (2004) J. Clin. Invest. 114, 643-651
23. Zuo, Y., Matsusaka, T., Zhong, J., Ma, J., Ma, L. J., Hanna, Z., Jolicoeur, P., Fogo, A. B., and Ichikawa, I. (2006) J. Am. Soc. Nephrol. 17, 2832-2843
24. Mundel, P., and Shankland, S. J. (2002) J. Am. Soc. Nephrol. 13, 3005-3015
25. Ichimura, K., Kurihara, H., and Sakai, T. (2003) J. Histochem. Cytochem. 51, 1589-1600
26. Barisoni, L., Bruggeman, L. A., Mundel, P., D'Agati, V. D., and Klotman, P. E. (2000) Kidney Int. 58, 173-181
27. Schwartz, E. J., Cara, A., Snoeck, H., Ross, M. D., Sunamoto, M., Reiser, J., Mundel, P., and Klotman, P. E. (2001) J. Am. Soc. Nephrol. 12, 1677-1684
28. Ridley, A. J. (1999) Nat. Cell Biol. 1, E64-E66
29. Ridley, A. J., and Hall, A. (1992) Cold Spring Harb. Symp. Quant. Biol. 57, 661-671
30. Fackler, O. T., Luo, W., Geyer, M., Alberts, A. S., and Peterlin, B. M. (1999) Mol. Cell 3, 729-739
31. Settleman, J., Narasimhan, V., Foster, L. C., and Weinberg, R. A. (1992) Cell 69, 539-549
32. Chang, J. H., Gill, S., Settleman, J., and Parsons, S. J. (1995) J. Cell Biol. 130, 355-368
33. Meng, W., Numazaki, M., Takeuchi, K., Uchibori, Y., Ando-Akatsuka, Y., Tominaga, M., and Tominaga, T. (2004) EMBO J. 23, 760-771
34. Saleem, M. A., O'Hare, M. J., Reiser, J., Coward, R. J., Inward, C. D., Farren, T., Xing, C. Y., Ni, L., Mathieson, P. W., and Mundel, P. (2002) J. Am. Soc. Nephrol. 13, 630-638
35. Chuang, P. Y., Yu, Q., Fang, W., Uribarri, J., and He, J. C. (2007) Kidney Int. 72, 965-976
36. Satoh, S., and Tominaga, T. (2001) J. Biol. Chem. 276, 39290-39294
37. Mundel, P., Reiser, J., Zuniga Mejia Borja, A., Pavenstadt, H., Davidson, G. R., Kriz, W., and Zeller, R. (1997) Exp. Cell Res. 236, 248-258
38. Ye, H., Choi, H. J., Poe, J., and Smithgall, T. E. (2004) Biochemistry 43, 15775-15784
39. Asanuma, K., Kim, K., Oh, J., Giardino, L., Chabanis, S., Faul, C., Reiser, J., and Mundel, P. (2005) J. Clin. Invest. 115, 1188-1198
40. Zondag, G. C., Evers, E. E., ten Klooster, J. P., Janssen, L., van der Kammen, R. A., and Collard, J. G. (2000) J. Cell Biol. 149, 775-782
41. Sander, E. E., ten Klooster, J. P., van Delft, S., van der Kammen, R. A., and Collard, J. G. (1999) J. Cell Biol. 147, 1009-1022
42. D'Agati, V., and Appel, G. B. (1997) J. Am. Soc. Nephrol. 8, 138-152
43. Thoulouze, M. I., Sol-Foulon, N., Blanchet, F., Dautry-Varsat, A., Schwartz, O., and Alcover, A. (2006) Immunity 24, 547-561
44. Dennis, C. A., Baron, A., Grossmann, J. G., Mazaleyrat, S., Harris, M., and Jaeger, J. (2005) Proteins 60, 658-669
45. Liu, L. X., Heveker, N., Fackler, O. T., Arold, S., Le Gall, S., Janvier, K., Peterlin, B. M., Dumas, C., Schwartz, O., Benichou, S., and Benarous, R. (2000) J. Virol. 74, 5310-5319
46. Asanuma, K., Yanagida-Asanuma, E., Faul, C., Tomino, Y., Kim, K., and Mundel, P. (2006) Nat. Cell Biol. 8, 485-491
47. Kos, C. H., Le, T. C., Sinha, S., Henderson, J. M., Kim, S. H., Sugimoto, H., Kalluri, R., Gerszten, R. E., and Pollak, M. R. (2003) J. Clin. Invest. 111, 1683-1690