Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6

Nature Medicine

Volumn 16, Issue 1, 2010, Pages 67-74

  Doi, Masao ^a   Takahashi, Yukari ^a   Komatsu, Rie ^a   Yamazaki, Fumiyoshi ^a   Yamada, Hiroyuki ^a   Haraguchi, Shogo ^b   Emoto, Noriaki ^c   Okuno, Yasushi ^a   Tsujimoto, Gozoh ^a   Kanematsu, Akihiro ^a   Ogawa, Osamu ^a   Todo, Takeshi ^d   Tsutsui, Kazuyoshi ^b   Van Der Horst, Gijsbertus T J ^e   Okamura, Hitoshi ^a  

^a KYOTO UNIVERSITY   (Japan)

^b WASEDA UNIVERSITY   (Japan)

^c KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

3 BETA HYDROXYSTEROID DEHYDROGENASE ISOMERASE; ALDOSTERONE; CRYPTOCHROME 1; CRYPTOCHROME 2; ISOMERASE; MESSENGER RNA; STEROID REDUCTASE; TYPE VI 3BETA HYDROXYL STEROID DEHYDROGENASE; UNCLASSIFIED DRUG;

ADRENAL GLAND; ALDOSTERONE RELEASE; ANIMAL EXPERIMENT; ARTICLE; CIRCADIAN RHYTHM; ENZYME ACTIVITY; GENE EXPRESSION; HORMONE SYNTHESIS; HUMAN; HYPERTENSION; MOUSE; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK FACTOR; TRANSCRIPTION REGULATION; ZONA GLOMERULOSA;

ALDOSTERONE; ANIMALS; CIRCADIAN RHYTHM; CRYPTOCHROMES; GENE EXPRESSION REGULATION; HUMANS; HYPERTENSION; ISOENZYMES; MICE; MICE, KNOCKOUT; PROGESTERONE REDUCTASE; STEROID ISOMERASES; ZONA GLOMERULOSA;

MUS;

EID: 73849110168     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2061     Document Type: Article

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