-
1
-
-
35548936833
-
Models, mechanisms and clinical evidence for cancer dormancy
-
J.A. Aguirre-Ghiso Models, mechanisms and clinical evidence for cancer dormancy Nature Reviews Cancer 7 2007 834 846
-
(2007)
Nature Reviews Cancer
, vol.7
, pp. 834-846
-
-
Aguirre-Ghiso, J.A.1
-
2
-
-
79951847989
-
Principles and current strategies for targeting autophagy for cancer treatment
-
R.K. Amaravadi, J. Lippincott-Schwartz, X.M. Yin, W.A. Weiss, N. Takebe, and W. Timmer Principles and current strategies for targeting autophagy for cancer treatment Clinical Cancer Research 17 2011 654 666
-
(2011)
Clinical Cancer Research
, vol.17
, pp. 654-666
-
-
Amaravadi, R.K.1
Lippincott-Schwartz, J.2
Yin, X.M.3
Weiss, W.A.4
Takebe, N.5
Timmer, W.6
-
3
-
-
34948820602
-
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
-
L. Apetoh, F. Ghiringhelli, A. Tesniere, M. Obeid, C. Ortiz, and A. Criollo Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy Nature Medicine 13 2007 1050 1059
-
(2007)
Nature Medicine
, vol.13
, pp. 1050-1059
-
-
Apetoh, L.1
Ghiringhelli, F.2
Tesniere, A.3
Obeid, M.4
Ortiz, C.5
Criollo, A.6
-
4
-
-
84855547801
-
Hydrophobic statins induce autophagy and cell death in human rhabdomyosarcoma cells by depleting geranylgeranyl diphosphate
-
M. Araki, M. Maeda, and K. Motojima Hydrophobic statins induce autophagy and cell death in human rhabdomyosarcoma cells by depleting geranylgeranyl diphosphate European Journal of Pharmacology 674 2011 95 103
-
(2011)
European Journal of Pharmacology
, vol.674
, pp. 95-103
-
-
Araki, M.1
Maeda, M.2
Motojima, K.3
-
5
-
-
38349074872
-
Hydrophobic statins induce autophagy in cultured human rhabdomyosarcoma cells
-
M. Araki, and K. Motojima Hydrophobic statins induce autophagy in cultured human rhabdomyosarcoma cells Biochemical and Biophysical Research Communications 367 2008 462 467
-
(2008)
Biochemical and Biophysical Research Communications
, vol.367
, pp. 462-467
-
-
Araki, M.1
Motojima, K.2
-
6
-
-
78049523865
-
Effect of statin therapy on colorectal cancer
-
M. Bardou, A. Barkun, and M. Martel Effect of statin therapy on colorectal cancer Gut 59 2010 1572 1585
-
(2010)
Gut
, vol.59
, pp. 1572-1585
-
-
Bardou, M.1
Barkun, A.2
Martel, M.3
-
7
-
-
0036187615
-
The role of tumour-Associated macrophages in tumour progression: Implications for new anticancer therapies
-
L. Bingle, N. Brown, and C. Lewis The role of tumour-Associated macrophages in tumour progression: implications for new anticancer therapies The Journal of Pathology 196 2002 254 265
-
(2002)
The Journal of Pathology
, vol.196
, pp. 254-265
-
-
Bingle, L.1
Brown, N.2
Lewis, C.3
-
8
-
-
62649086172
-
The pleiotropic effects of statins on endothelial function, vascular inflammation, immunomodulation and thrombogenesis
-
A. Blum, and R. Shamburek The pleiotropic effects of statins on endothelial function, vascular inflammation, immunomodulation and thrombogenesis Atherosclerosis 203 2009 325 330
-
(2009)
Atherosclerosis
, vol.203
, pp. 325-330
-
-
Blum, A.1
Shamburek, R.2
-
10
-
-
78751556979
-
Autophagy as a therapeutic target in cancer
-
N. Chen, and V. Karantza Autophagy as a therapeutic target in cancer Cancer Biology & Therapy 11 2011 157
-
(2011)
Cancer Biology & Therapy
, vol.11
, pp. 157
-
-
Chen, N.1
Karantza, V.2
-
11
-
-
55949128465
-
Anoikis: A necessary death program for anchorage-dependent cells
-
P. Chiarugi, and E. Giannoni Anoikis: a necessary death program for anchorage-dependent cells Biochemical Pharmacology 76 2008 1352 1364
-
(2008)
Biochemical Pharmacology
, vol.76
, pp. 1352-1364
-
-
Chiarugi, P.1
Giannoni, E.2
-
12
-
-
70349258349
-
Immunomodulation by statins: Mechanisms and potential impact on autoimmune diseases
-
S.C. Chow Immunomodulation by statins: mechanisms and potential impact on autoimmune diseases Archivum immunologiae et therapiae experimentalis 57 2009 243 251
-
(2009)
Archivum Immunologiae et Therapiae Experimentalis
, vol.57
, pp. 243-251
-
-
Chow, S.C.1
-
13
-
-
2442706575
-
Atorvastatin prevents RhoC isoprenylation, invasion, and metastasis in human melanoma cells
-
E.A. Collisson, C. Kleer, M. Wu, A. De, S.S. Gambhir, and S.D. Merajver Atorvastatin prevents RhoC isoprenylation, invasion, and metastasis in human melanoma cells Molecular Cancer Therapeutics 2 2003 941
-
(2003)
Molecular Cancer Therapeutics
, vol.2
, pp. 941
-
-
Collisson, E.A.1
Kleer, C.2
Wu, M.3
De, A.4
Gambhir, S.S.5
Merajver, S.D.6
-
14
-
-
0037020196
-
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini
-
J. Debnath, K.R. Mills, N.L. Collins, M.J. Reginato, S.K. Muthuswamy, and J.S. Brugge The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini Cell 111 2002 29 40
-
(2002)
Cell
, vol.111
, pp. 29-40
-
-
Debnath, J.1
Mills, K.R.2
Collins, N.L.3
Reginato, M.J.4
Muthuswamy, S.K.5
Brugge, J.S.6
-
15
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
K. Degenhardt, R. Mathew, B. Beaudoin, K. Bray, D. Anderson, and G. Chen Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis Cancer Cell 10 2006 51 64
-
(2006)
Cancer Cell
, vol.10
, pp. 51-64
-
-
Degenhardt, K.1
Mathew, R.2
Beaudoin, B.3
Bray, K.4
Anderson, D.5
Chen, G.6
-
16
-
-
28844490054
-
Statins and cancer prevention
-
M.F. Demierre, P.D.R. Higgins, S.B. Gruber, E. Hawk, and S.M. Lippman Statins and cancer prevention Nature Reviews Cancer 5 2005 930 942
-
(2005)
Nature Reviews Cancer
, vol.5
, pp. 930-942
-
-
Demierre, M.F.1
Higgins, P.D.R.2
Gruber, S.B.3
Hawk, E.4
Lippman, S.M.5
-
18
-
-
0346826281
-
Molecular mechanism of the anti-cancer activity of cerivastatin, an inhibitor of HMG-CoA reductase, on aggressive human breast cancer cells
-
C. Denoyelle, P. Albanese, G. Uzan, L. Hong, J.P. Vannier, and J. Soria Molecular mechanism of the anti-cancer activity of cerivastatin, an inhibitor of HMG-CoA reductase, on aggressive human breast cancer cells Cellular Signalling 15 2003 327 338
-
(2003)
Cellular Signalling
, vol.15
, pp. 327-338
-
-
Denoyelle, C.1
Albanese, P.2
Uzan, G.3
Hong, L.4
Vannier, J.P.5
Soria, J.6
-
19
-
-
4344627055
-
Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB
-
S. Douma, T. Van Laar, J. Zevenhoven, R. Meuwissen, E. Van Garderen, and D.S. Peeper Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB Nature 430 2004 1034 1039
-
(2004)
Nature
, vol.430
, pp. 1034-1039
-
-
Douma, S.1
Van Laar, T.2
Zevenhoven, J.3
Meuwissen, R.4
Van Garderen, E.5
Peeper, D.S.6
-
20
-
-
0036395370
-
Lovastatin alters cytoskeleton organization and inhibits experimental metastasis of mammary carcinoma cells
-
H.G. Farina, D.R. Bublik, D.F. Alonso, and D.E. Gomez Lovastatin alters cytoskeleton organization and inhibits experimental metastasis of mammary carcinoma cells Clinical and Experimental Metastasis 19 2002 551 560
-
(2002)
Clinical and Experimental Metastasis
, vol.19
, pp. 551-560
-
-
Farina, H.G.1
Bublik, D.R.2
Alonso, D.F.3
Gomez, D.E.4
-
21
-
-
41449109334
-
Induction of autophagy during extracellular matrix detachment promotes cell survival
-
C. Fung, R. Lock, S. Gao, E. Salas, and J. Debnath Induction of autophagy during extracellular matrix detachment promotes cell survival Molecular Biology of the Cell 19 2008 797 806
-
(2008)
Molecular Biology of the Cell
, vol.19
, pp. 797-806
-
-
Fung, C.1
Lock, R.2
Gao, S.3
Salas, E.4
Debnath, J.5
-
22
-
-
83455163746
-
Pharmacological actions of statins: A critical appraisal in the management of cancer
-
P. Gazzerro, M.C. Proto, G. Gangemi, A.M. Malfitano, E. Ciaglia, and S. Pisanti Pharmacological actions of statins: a critical appraisal in the management of cancer Pharmacological Reviews 64 2012 102 146
-
(2012)
Pharmacological Reviews
, vol.64
, pp. 102-146
-
-
Gazzerro, P.1
Proto, M.C.2
Gangemi, G.3
Malfitano, A.M.4
Ciaglia, E.5
Pisanti, S.6
-
23
-
-
79551622901
-
Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: A dual role for p53
-
S. Ghavami, M.M. Mutawe, P. Sharma, B. Yeganeh, K.D. McNeill, and T. Klonisch Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53 PLoS ONE 6 2011 e16523
-
(2011)
PLoS ONE
, vol.6
, pp. 16523
-
-
Ghavami, S.1
Mutawe, M.M.2
Sharma, P.3
Yeganeh, B.4
McNeill, K.D.5
Klonisch, T.6
-
24
-
-
84863425318
-
Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts
-
S. Ghavami, B. Yeganeh, G. Stelmack, H. Kashani, P. Sharma, and R. Cunnington Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts Cell Death & Disease 3 2012 e330
-
(2012)
Cell Death & Disease
, vol.3
, pp. 330
-
-
Ghavami, S.1
Yeganeh, B.2
Stelmack, G.3
Kashani, H.4
Sharma, P.5
Cunnington, R.6
-
25
-
-
44949133351
-
Tumor versus tumor-Associated macrophages: How hot is the link?
-
C. Guruvayoorappan Tumor versus tumor-Associated macrophages: how hot is the link? Integrative Cancer Therapies 7 2008 90 95
-
(2008)
Integrative Cancer Therapies
, vol.7
, pp. 90-95
-
-
Guruvayoorappan, C.1
-
26
-
-
0344013648
-
Inhibition of hydroxymethylglutaryl-coenzyme a reductase reduces Th1 development and promotes Th2 development
-
R. Hakamada-Taguchi, Y. Uehara, K. Kuribayashi, A. Numabe, K. Saito, and H. Negoro Inhibition of hydroxymethylglutaryl-coenzyme a reductase reduces Th1 development and promotes Th2 development Circulation Research 93 2003 948 956
-
(2003)
Circulation Research
, vol.93
, pp. 948-956
-
-
Hakamada-Taguchi, R.1
Uehara, Y.2
Kuribayashi, K.3
Numabe, A.4
Saito, K.5
Negoro, H.6
-
27
-
-
72549095406
-
Regulation mechanisms and signaling pathways of autophagy
-
C. He, and D.J. Klionsky Regulation mechanisms and signaling pathways of autophagy Annual Review of Genetics 43 2009 67
-
(2009)
Annual Review of Genetics
, vol.43
, pp. 67
-
-
He, C.1
Klionsky, D.J.2
-
28
-
-
0028274845
-
The role of isoprenylation in membrane attachment of nuclear lamins. A single point mutation prevents proteolytic cleavage of the lamin A precursor and confers membrane binding properties
-
H. Hennekes, and E.A. Nigg The role of isoprenylation in membrane attachment of nuclear lamins. A single point mutation prevents proteolytic cleavage of the lamin A precursor and confers membrane binding properties Journal of Cell Science 107 1994 1019 1029
-
(1994)
Journal of Cell Science
, vol.107
, pp. 1019-1029
-
-
Hennekes, H.1
Nigg, E.A.2
-
29
-
-
11144238571
-
3-Hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor, fluvastatin, as a novel agent for prophylaxis of renal cancer metastasis
-
A. Horiguchi, M. Sumitomo, J. Asakuma, T. Asano, and M. Hayakawa 3-Hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor, fluvastatin, as a novel agent for prophylaxis of renal cancer metastasis Clinical Cancer Research 10 2004 8648 8655
-
(2004)
Clinical Cancer Research
, vol.10
, pp. 8648-8655
-
-
Horiguchi, A.1
Sumitomo, M.2
Asakuma, J.3
Asano, T.4
Hayakawa, M.5
-
30
-
-
84860159791
-
Inhibitors of phosphatidylinositol 3′-kinases promote mitotic cell death in HeLa cells
-
H. Hou, Y. Zhang, Y. Huang, Q. Yi, L. Lv, and T. Zhang Inhibitors of phosphatidylinositol 3′-kinases promote mitotic cell death in HeLa cells PLoS ONE 7 2012 e35665
-
(2012)
PLoS ONE
, vol.7
, pp. 35665
-
-
Hou, H.1
Zhang, Y.2
Huang, Y.3
Yi, Q.4
Lv, L.5
Zhang, T.6
-
31
-
-
63049104211
-
Microenvironmental regulation of metastasis
-
J.A. Joyce, and J.W. Pollard Microenvironmental regulation of metastasis Nature Reviews Cancer 9 2008 239 252
-
(2008)
Nature Reviews Cancer
, vol.9
, pp. 239-252
-
-
Joyce, J.A.1
Pollard, J.W.2
-
32
-
-
20844451123
-
AMP-Activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
-
B.B. Kahn, T. Alquier, D. Carling, and D.G. Hardie AMP-Activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism Cell Metabolism 1 2005 15 25
-
(2005)
Cell Metabolism
, vol.1
, pp. 15-25
-
-
Kahn, B.B.1
Alquier, T.2
Carling, D.3
Hardie, D.G.4
-
33
-
-
0034948339
-
Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site
-
C.B. Kallen, S. Cottens, Y. Takada, and U. Hommel Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site Nature Medicine 7 2001 687
-
(2001)
Nature Medicine
, vol.7
, pp. 687
-
-
Kallen, C.B.1
Cottens, S.2
Takada, Y.3
Hommel, U.4
-
34
-
-
20344365809
-
Therapy insight: Potential of statins for cancer chemoprevention and therapy
-
M.S. Katz Therapy insight: potential of statins for cancer chemoprevention and therapy Nature Reviews Clinical Oncology 2 2005 82 89
-
(2005)
Nature Reviews Clinical Oncology
, vol.2
, pp. 82-89
-
-
Katz, M.S.1
-
36
-
-
0037016752
-
Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior tode novo vesicle formation
-
J. Kim, W.P. Huang, P.E. Stromhaug, and D.J. Klionsky Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior tode novo vesicle formation Journal of Biological Chemistry 277 2002 763 773
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 763-773
-
-
Kim, J.1
Huang, W.P.2
Stromhaug, P.E.3
Klionsky, D.J.4
-
37
-
-
84863357474
-
Anoikis resistance: An essential prerequisite for tumor metastasis
-
Y.N. Kim, K.H. Koo, J.Y. Sung, U.J. Yun, and H. Kim Anoikis resistance: an essential prerequisite for tumor metastasis International Journal of Cell Biology 2012 2012
-
(2012)
International Journal of Cell Biology
, pp. 2012
-
-
Kim, Y.N.1
Koo, K.H.2
Sung, J.Y.3
Yun, U.J.4
Kim, H.5
-
38
-
-
0035874879
-
Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors
-
T. Kusama, M. Mukai, T. Iwasaki, M. Tatsuta, Y. Matsumoto, and H. Akedo Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors Cancer Research 61 2001 4885
-
(2001)
Cancer Research
, vol.61
, pp. 4885
-
-
Kusama, T.1
Mukai, M.2
Iwasaki, T.3
Tatsuta, M.4
Matsumoto, Y.5
Akedo, H.6
-
39
-
-
0034533147
-
Statins as a newly recognized type of immunomodulator
-
B. Kwak, F. Mulhaupt, S. Myit, and F. Mach Statins as a newly recognized type of immunomodulator Nature Medicine 6 2000 1399 1402
-
(2000)
Nature Medicine
, vol.6
, pp. 1399-1402
-
-
Kwak, B.1
Mulhaupt, F.2
Myit, S.3
MacH, F.4
-
40
-
-
84861198406
-
Simvastatin alleviates the progression of periapical lesions by modulating autophagy and apoptosis in osteoblasts
-
E.H.H. Lai, C.Y. Hong, S.H. Kok, K.L. Hou, L.H. Chao, and L.D. Lin Simvastatin alleviates the progression of periapical lesions by modulating autophagy and apoptosis in osteoblasts Journal of Endodontics 38 2012 757 763
-
(2012)
Journal of Endodontics
, vol.38
, pp. 757-763
-
-
Lai, E.H.H.1
Hong, C.Y.2
Kok, S.H.3
Hou, K.L.4
Chao, L.H.5
Lin, L.D.6
-
41
-
-
82555181278
-
Tumor-Associated macrophages in breast cancer: Distinct subsets, distinct functions
-
D. Laoui, K. Movahedi, E. Van Overmeire, J. Van den Bossche, E. Schouppe, and C. Mommer Tumor-Associated macrophages in breast cancer: distinct subsets, distinct functions The International Journal of Developmental Biology 55 2011 861
-
(2011)
The International Journal of Developmental Biology
, vol.55
, pp. 861
-
-
Laoui, D.1
Movahedi, K.2
Van Overmeire, E.3
Van Den Bossche, J.4
Schouppe, E.5
Mommer, C.6
-
42
-
-
84857723095
-
Here, there be dragons: Charting autophagy-related alterations in human tumors
-
C.B. Lebovitz, S.B. Bortnik, and S.M. Gorski Here, there be dragons: charting autophagy-related alterations in human tumors Clinical Cancer Research 18 2012 1214 1226
-
(2012)
Clinical Cancer Research
, vol.18
, pp. 1214-1226
-
-
Lebovitz, C.B.1
Bortnik, S.B.2
Gorski, S.M.3
-
44
-
-
42049088710
-
Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-Associated HDAC1/2
-
Y.C. Lin, J.H. Lin, C.W. Chou, Y.F. Chang, S.H. Yeh, and C.C. Chen Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-Associated HDAC1/2 Cancer Research 68 2008 2375
-
(2008)
Cancer Research
, vol.68
, pp. 2375
-
-
Lin, Y.C.1
Lin, J.H.2
Chou, C.W.3
Chang, Y.F.4
Yeh, S.H.5
Chen, C.C.6
-
45
-
-
78649299438
-
Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma
-
Y.L. Liu, P.M. Yang, C.T. Shun, M.S. Wu, J.R. Weng, and C.C. Chen Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma Autophagy 6 2010 1057
-
(2010)
Autophagy
, vol.6
, pp. 1057
-
-
Liu, Y.L.1
Yang, P.M.2
Shun, C.T.3
Wu, M.S.4
Weng, J.R.5
Chen, C.C.6
-
47
-
-
77951243028
-
Autophagy regulation by p53
-
M.C. Maiuri, L. Galluzzi, E. Morselli, O. Kepp, S.A. Malik, and G. Kroemer Autophagy regulation by p53 Current Opinion in Cell Biology 22 2010 181 185
-
(2010)
Current Opinion in Cell Biology
, vol.22
, pp. 181-185
-
-
Maiuri, M.C.1
Galluzzi, L.2
Morselli, E.3
Kepp, O.4
Malik, S.A.5
Kroemer, G.6
-
48
-
-
0141756144
-
Role of Rho-family proteins in cell adhesion and cancer
-
A. Malliri, and J.G. Collard Role of Rho-family proteins in cell adhesion and cancer Current Opinion in Cell Biology 15 2003 583 589
-
(2003)
Current Opinion in Cell Biology
, vol.15
, pp. 583-589
-
-
Malliri, A.1
Collard, J.G.2
-
49
-
-
79953217743
-
Simvastatin prevents skeletal metastasis of breast cancer by an antagonistic interplay between p53 and CD44
-
C.C. Mandal, N. Ghosh-Choudhury, T. Yoneda, and G.G. Choudhury Simvastatin prevents skeletal metastasis of breast cancer by an antagonistic interplay between p53 and CD44 Journal of Biological Chemistry 286 2011 11314
-
(2011)
Journal of Biological Chemistry
, vol.286
, pp. 11314
-
-
Mandal, C.C.1
Ghosh-Choudhury, N.2
Yoneda, T.3
Choudhury, G.G.4
-
51
-
-
14644402451
-
Geranylgeranylated, but not farnesylated, RhoB suppresses Ras transformation of NIH-3T3 cells
-
J. Mazières, V. Tillement, C. Allal, C. Clanet, L. Bobin, and Z. Chen Geranylgeranylated, but not farnesylated, RhoB suppresses Ras transformation of NIH-3T3 cells Experimental Cell Research 304 2005 354 364
-
(2005)
Experimental Cell Research
, vol.304
, pp. 354-364
-
-
Mazières, J.1
Tillement, V.2
Allal, C.3
Clanet, C.4
Bobin, L.5
Chen, Z.6
-
53
-
-
34248593475
-
AMP-Activated protein kinase and autophagy
-
A.J. Meijer, and P. Codogno AMP-Activated protein kinase and autophagy Autophagy 3 2007 238
-
(2007)
Autophagy
, vol.3
, pp. 238
-
-
Meijer, A.J.1
Codogno, P.2
-
54
-
-
33845924783
-
AMP-Activated protein kinase and the regulation of autophagic proteolysis
-
D. Meley, C. Bauvy, J.H.P.M. Houben-Weerts, P.F. Dubbelhuis, M.T.J. Helmond, and P. Codogno AMP-Activated protein kinase and the regulation of autophagic proteolysis Journal of Biological Chemistry 281 2006 34870 34879
-
(2006)
Journal of Biological Chemistry
, vol.281
, pp. 34870-34879
-
-
Meley, D.1
Bauvy, C.2
Houben-Weerts, J.H.P.M.3
Dubbelhuis, P.F.4
Helmond, M.T.J.5
Codogno, P.6
-
55
-
-
84856008689
-
Inhibition of AMPK-dependent autophagy enhances in vitro antiglioma effect of simvastatin
-
M. Misirkic, K. Janjetovic, L. Vucicevic, G. Tovilovic, B. Ristic, and U. Vilimanovich Inhibition of AMPK-dependent autophagy enhances in vitro antiglioma effect of simvastatin Pharmacological Research 65 2011 111 119
-
(2011)
Pharmacological Research
, vol.65
, pp. 111-119
-
-
Misirkic, M.1
Janjetovic, K.2
Vucicevic, L.3
Tovilovic, G.4
Ristic, B.5
Vilimanovich, U.6
-
56
-
-
0035911162
-
Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells
-
N. Mizushima, A. Yamamoto, M. Hatano, Y. Kobayashi, Y. Kabeya, and K. Suzuki Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells The Journal of Cell Biology 152 2001 657 668
-
(2001)
The Journal of Cell Biology
, vol.152
, pp. 657-668
-
-
Mizushima, N.1
Yamamoto, A.2
Hatano, M.3
Kobayashi, Y.4
Kabeya, Y.5
Suzuki, K.6
-
57
-
-
63049090100
-
Metastasis: From dissemination to organ-specific colonization
-
D.X. Nguyen, P.D. Bos, and J. Massagué Metastasis: from dissemination to organ-specific colonization Nature Reviews Cancer 9 2009 274 284
-
(2009)
Nature Reviews Cancer
, vol.9
, pp. 274-284
-
-
Nguyen, D.X.1
Bos, P.D.2
Massagué, J.3
-
58
-
-
84873414109
-
The anti-tumor activities of statins
-
M. Nishibori The anti-tumor activities of statins Current Oncology 2007 14
-
(2007)
Current Oncology
, pp. 14
-
-
Nishibori, M.1
-
59
-
-
84864031857
-
Statins and cancer: Current and future prospects
-
M. Osmak Statins and cancer: current and future prospects Cancer Letters 324 2012 1 12
-
(2012)
Cancer Letters
, vol.324
, pp. 1-12
-
-
Osmak, M.1
-
60
-
-
77952933689
-
Statin-induced autophagy by inhibition of geranylgeranyl biosynthesis in prostate cancer PC3 cells
-
A. Parikh, C. Childress, K. Deitrick, Q. Lin, D. Rukstalis, and W. Yang Statin-induced autophagy by inhibition of geranylgeranyl biosynthesis in prostate cancer PC3 cells The Prostate 70 2010 971 981
-
(2010)
The Prostate
, vol.70
, pp. 971-981
-
-
Parikh, A.1
Childress, C.2
Deitrick, K.3
Lin, Q.4
Rukstalis, D.5
Yang, W.6
-
61
-
-
68049104247
-
Autophagy: Molecular machinery, regulation, and implications for renal pathophysiology
-
S. Periyasamy-Thandavan, M. Jiang, P. Schoenlein, and Z. Dong Autophagy: molecular machinery, regulation, and implications for renal pathophysiology American Journal of Physiology-Renal Physiology 297 2009 F244 F256
-
(2009)
American Journal of Physiology-Renal Physiology
, vol.297
-
-
Periyasamy-Thandavan, S.1
Jiang, M.2
Schoenlein, P.3
Dong, Z.4
-
62
-
-
0033529171
-
Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase
-
S. Rao, D.C. Porter, X. Chen, T. Herliczek, M. Lowe, and K. Keyomarsi Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase Proceedings of the National Academy of Sciences 96 1999 7797
-
(1999)
Proceedings of the National Academy of Sciences
, vol.96
, pp. 7797
-
-
Rao, S.1
Porter, D.C.2
Chen, X.3
Herliczek, T.4
Lowe, M.5
Keyomarsi, K.6
-
63
-
-
84860710342
-
Statins and prostate cancer: Role of cholesterol inhibition vs. prevention of small GTP-binding proteins
-
M. Roy, H.J. Kung, and P.M. Ghosh Statins and prostate cancer: role of cholesterol inhibition vs. prevention of small GTP-binding proteins American Journal of Cancer Research 1 2011 542
-
(2011)
American Journal of Cancer Research
, vol.1
, pp. 542
-
-
Roy, M.1
Kung, H.J.2
Ghosh, P.M.3
-
64
-
-
73349125101
-
Role of isoprenylation in simvastatin-induced inhibition of ovarian theca-interstitial growth in the rat
-
I.J. Rzepczynska, P.C. Piotrowski, D.H. Wong, A.B. Cress, J. Villanueva, and A.J. Duleba Role of isoprenylation in simvastatin-induced inhibition of ovarian theca-interstitial growth in the rat Biology of Reproduction 81 2009 850 855
-
(2009)
Biology of Reproduction
, vol.81
, pp. 850-855
-
-
Rzepczynska, I.J.1
Piotrowski, P.C.2
Wong, D.H.3
Cress, A.B.4
Villanueva, J.5
Duleba, A.J.6
-
65
-
-
77949697998
-
A novel geranylgeranyl transferase inhibitor in combination with lovastatin inhibits proliferation and induces autophagy in STS-26T MPNST cells
-
K.M. Sane, M. Mynderse, D.T. LaLonde, I.S. Dean, J.W. Wojtkowiak, and F. Fouad A novel geranylgeranyl transferase inhibitor in combination with lovastatin inhibits proliferation and induces autophagy in STS-26T MPNST cells Journal of Pharmacology and Experimental Therapeutics 333 2010 23 33
-
(2010)
Journal of Pharmacology and Experimental Therapeutics
, vol.333
, pp. 23-33
-
-
Sane, K.M.1
Mynderse, M.2
Lalonde, D.T.3
Dean, I.S.4
Wojtkowiak, J.W.5
Fouad, F.6
-
67
-
-
63849149937
-
LKB1 and AMP-Activated protein kinase control of mTOR signalling and growth
-
R.J. Shaw LKB1 and AMP-Activated protein kinase control of mTOR signalling and growth Acta Physiologica 196 2009 65 80
-
(2009)
Acta Physiologica
, vol.196
, pp. 65-80
-
-
Shaw, R.J.1
-
68
-
-
84873410001
-
Inhibition of atorvastatin on the autophagy of vascular endothelial cells
-
Z. Sheng-Xue, Q. Ling, X. Chuan-Shi, and F. Ya-Qin Inhibition of atorvastatin on the autophagy of vascular endothelial cells Heart 96 2010 A11 A12
-
(2010)
Heart
, vol.96
-
-
Sheng-Xue, Z.1
Ling, Q.2
Chuan-Shi, X.3
Ya-Qin, F.4
-
69
-
-
6444230927
-
Lovastatin inhibits tumor growth and lung metastasis in mouse mammary carcinoma model: A p53-independent mitochondrial-mediated apoptotic mechanism
-
M.A. Shibata, Y. Ito, J. Morimoto, and Y. Otsuki Lovastatin inhibits tumor growth and lung metastasis in mouse mammary carcinoma model: a p53-independent mitochondrial-mediated apoptotic mechanism Carcinogenesis 25 2004 1887 1898
-
(2004)
Carcinogenesis
, vol.25
, pp. 1887-1898
-
-
Shibata, M.A.1
Ito, Y.2
Morimoto, J.3
Otsuki, Y.4
-
70
-
-
84857788964
-
Role of tumor-Associated macrophages in the progression of hepatocellular carcinoma
-
K. Shirabe, Y. Mano, J. Muto, R. Matono, T. Motomura, and T. Toshima Role of tumor-Associated macrophages in the progression of hepatocellular carcinoma Surgery Today 2012 1 7
-
(2012)
Surgery Today
, pp. 1-7
-
-
Shirabe, K.1
Mano, Y.2
Muto, J.3
Matono, R.4
Motomura, T.5
Toshima, T.6
-
71
-
-
9244237677
-
Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma
-
K.J. Simpson, A.S. Dugan, and A.M. Mercurio Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma Cancer Research 64 2004 8694
-
(2004)
Cancer Research
, vol.64
, pp. 8694
-
-
Simpson, K.J.1
Dugan, A.S.2
Mercurio, A.M.3
-
72
-
-
11244313840
-
Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation
-
A. Singh, A.E. Karnoub, T.R. Palmby, E. Lengyel, J. Sondek, and C.J. Der Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation Oncogene 23 2004 9369 9380
-
(2004)
Oncogene
, vol.23
, pp. 9369-9380
-
-
Singh, A.1
Karnoub, A.E.2
Palmby, T.R.3
Lengyel, E.4
Sondek, J.5
Der, C.J.6
-
74
-
-
77954987492
-
Understanding micrometastatic disease and anoikis resistance in ewing family of tumors and osteosarcoma
-
S.J. Strauss, T. Ng, A. Mendoza-Naranjo, J. Whelan, and P.H.B. Sorensen Understanding micrometastatic disease and anoikis resistance in ewing family of tumors and osteosarcoma The Oncologist 15 2010 627 635
-
(2010)
The Oncologist
, vol.15
, pp. 627-635
-
-
Strauss, S.J.1
Ng, T.2
Mendoza-Naranjo, A.3
Whelan, J.4
Sorensen, P.H.B.5
-
75
-
-
0035503594
-
The pre-Autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation
-
K. Suzuki, T. Kirisako, Y. Kamada, N. Mizushima, T. Noda, and Y. Ohsumi The pre-Autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation The EMBO Journal 20 2001 5971 5981
-
(2001)
The EMBO Journal
, vol.20
, pp. 5971-5981
-
-
Suzuki, K.1
Kirisako, T.2
Kamada, Y.3
Mizushima, N.4
Noda, T.5
Ohsumi, Y.6
-
77
-
-
33751523611
-
Pravastatin reduces lung metastasis of rat hepatocellular carcinoma via a coordinated decrease of MMP expression and activity
-
D. Taras, J.F. Blanc, A. Rullier, N. Dugot-Senant, I. Laurendeau, and M. Vidaud Pravastatin reduces lung metastasis of rat hepatocellular carcinoma via a coordinated decrease of MMP expression and activity Journal of Hepatology 46 2007 69 76
-
(2007)
Journal of Hepatology
, vol.46
, pp. 69-76
-
-
Taras, D.1
Blanc, J.F.2
Rullier, A.3
Dugot-Senant, N.4
Laurendeau, I.5
Vidaud, M.6
-
78
-
-
50249145608
-
A dual role of p53 in the control of autophagy
-
E. Tasdemir, M. Chiara Maiuri, E. Morselli, A. Criollo, M. D'Amelio, and M. Djavaheri-Mergny A dual role of p53 in the control of autophagy Autophagy 4 2008 810 814
-
(2008)
Autophagy
, vol.4
, pp. 810-814
-
-
Tasdemir, E.1
Chiara Maiuri, M.2
Morselli, E.3
Criollo, A.4
D'Amelio, M.5
Djavaheri-Mergny, M.6
-
79
-
-
57649217868
-
Autophagy regulates selective HMGB1 release in tumor cells that are destined to die
-
J. Thorburn, H. Horita, J. Redzic, K. Hansen, A.E. Frankel, and A. Thorburn Autophagy regulates selective HMGB1 release in tumor cells that are destined to die Cell Death & Differentiation 16 2008 175 183
-
(2008)
Cell Death & Differentiation
, vol.16
, pp. 175-183
-
-
Thorburn, J.1
Horita, H.2
Redzic, J.3
Hansen, K.4
Frankel, A.E.5
Thorburn, A.6
-
81
-
-
81555210946
-
Depletion of tissue factor suppresses hepatic metastasis and tumor growth in colorectal cancer via the downregulation of MMPs and the induction of autophagy and apoptosis
-
M. Tian, Y. Wan, J. Tang, H. Li, G. Yu, and J. Zhu Depletion of tissue factor suppresses hepatic metastasis and tumor growth in colorectal cancer via the downregulation of MMPs and the induction of autophagy and apoptosis Cancer Biology & Therapy 12 2011 896 907
-
(2011)
Cancer Biology & Therapy
, vol.12
, pp. 896-907
-
-
Tian, M.1
Wan, Y.2
Tang, J.3
Li, H.4
Yu, G.5
Zhu, J.6
-
82
-
-
80054105509
-
Atorvastatin induces autophagy in prostate cancer PC3 cells through activation of LC3 transcription
-
N. Toepfer, C. Childress, A. Parikh, D. Rukstalis, and W. Yang Atorvastatin induces autophagy in prostate cancer PC3 cells through activation of LC3 transcription Cancer Biology & Therapy 12 2011 691 699
-
(2011)
Cancer Biology & Therapy
, vol.12
, pp. 691-699
-
-
Toepfer, N.1
Childress, C.2
Parikh, A.3
Rukstalis, D.4
Yang, W.5
-
83
-
-
0242290258
-
P21-Dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases
-
C. Ukomadu, and A. Dutta p21-Dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases Journal of Biological Chemistry 278 2003 43586 43594
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 43586-43594
-
-
Ukomadu, C.1
Dutta, A.2
-
84
-
-
78650835111
-
Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway
-
L. Vucicevic, M. Misirkic, K. Janjetovic, U. Vilimanovich, E. Sudar, and E. Isenovic Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway Autophagy 7 2011 40
-
(2011)
Autophagy
, vol.7
, pp. 40
-
-
Vucicevic, L.1
Misirkic, M.2
Janjetovic, K.3
Vilimanovich, U.4
Sudar, E.5
Isenovic, E.6
-
85
-
-
53549089861
-
Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation
-
Y. Wei, S. Sinha, and B. Levine Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation Autophagy 4 2008 949
-
(2008)
Autophagy
, vol.4
, pp. 949
-
-
Wei, Y.1
Sinha, S.2
Levine, B.3
-
86
-
-
5144235557
-
Targeted disruption of β1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction
-
D.E. White, N.A. Kurpios, D. Zuo, J.A. Hassell, S. Blaess, and U. Mueller Targeted disruption of β1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction Cancer Cell 6 2004 159 170
-
(2004)
Cancer Cell
, vol.6
, pp. 159-170
-
-
White, D.E.1
Kurpios, N.A.2
Zuo, D.3
Hassell, J.A.4
Blaess, S.5
Mueller, U.6
-
87
-
-
69949106925
-
The double-edged sword of autophagy modulation in cancer
-
E. White, and R.S. DiPaola The double-edged sword of autophagy modulation in cancer Clinical Cancer Research 15 2009 5308 5316
-
(2009)
Clinical Cancer Research
, vol.15
, pp. 5308-5316
-
-
White, E.1
Dipaola, R.S.2
-
88
-
-
79952996848
-
Aborted autophagy and nonapoptotic death induced by farnesyl transferase inhibitor and lovastatin
-
J.W. Wojtkowiak, K.M. Sane, M. Kleinman, B.F. Sloane, J.J. Reiners Jr., and R.R. Mattingly Aborted autophagy and nonapoptotic death induced by farnesyl transferase inhibitor and lovastatin Journal of Pharmacology and Experimental Therapeutics 337 2011 65 74
-
(2011)
Journal of Pharmacology and Experimental Therapeutics
, vol.337
, pp. 65-74
-
-
Wojtkowiak, J.W.1
Sane, K.M.2
Kleinman, M.3
Sloane, B.F.4
Reiners, Jr.J.J.5
Mattingly, R.R.6
-
89
-
-
80052731707
-
Timing is critical for an effective anti-metastatic immunotherapy: The decisive role of IFNγ/STAT1-mediated activation of autophagy
-
J. Yan, Z.Y. Wang, H.Z. Yang, H.Z. Liu, S. Mi, and X.X. Lv Timing is critical for an effective anti-metastatic immunotherapy: the decisive role of IFNγ/STAT1-mediated activation of autophagy PLoS ONE 6 2011 e24705
-
(2011)
PLoS ONE
, vol.6
, pp. 24705
-
-
Yan, J.1
Wang, Z.Y.2
Yang, H.Z.3
Liu, H.Z.4
Mi, S.5
Lv, X.X.6
-
91
-
-
77957367974
-
Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies
-
P.M. Yang, Y.L. Liu, Y.C. Lin, C.T. Shun, M.S. Wu, and C.C. Chen Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies Cancer Research 70 2010 7699 7709
-
(2010)
Cancer Research
, vol.70
, pp. 7699-7709
-
-
Yang, P.M.1
Liu, Y.L.2
Lin, Y.C.3
Shun, C.T.4
Wu, M.S.5
Chen, C.C.6
-
92
-
-
77956404377
-
Eaten alive: A history of macroautophagy
-
Z. Yang, and D.J. Klionsky Eaten alive: a history of macroautophagy Nature Cell Biology 12 2010 814 822
-
(2010)
Nature Cell Biology
, vol.12
, pp. 814-822
-
-
Yang, Z.1
Klionsky, D.J.2
-
93
-
-
73149089908
-
Treatment of metastatic spinal tumors by percutaneous vertebroplasty versus percutaneous vertebroplasty combined with interstitial implantation of 125I seeds
-
Z. Yang, D. Yang, L. Xie, Y. Sun, Y. Huang, and H. Sun Treatment of metastatic spinal tumors by percutaneous vertebroplasty versus percutaneous vertebroplasty combined with interstitial implantation of 125I seeds Acta Radiologica 50 2009 1142 1148
-
(2009)
Acta Radiologica
, vol.50
, pp. 1142-1148
-
-
Yang, Z.1
Yang, D.2
Xie, L.3
Sun, Y.4
Huang, Y.5
Sun, H.6
-
94
-
-
57049186623
-
How to live long and prosper: Autophagy, mitochondria, and aging
-
W.L. Yen, and D.J. Klionsky How to live long and prosper: autophagy, mitochondria, and aging Physiology 23 2008 248 262
-
(2008)
Physiology
, vol.23
, pp. 248-262
-
-
Yen, W.L.1
Klionsky, D.J.2
-
95
-
-
84861983563
-
Autophagy activation: A novel mechanism of atorvastatin to protect mesenchymal stem cells from hypoxia and serum deprivation via AMP-Activated protein kinase/mammalian target of rapamycin pathway
-
Q. Zhang, Y.J. Yang, H. Wang, Q.T. Dong, T.J. Wang, and H.Y. Qian Autophagy activation: a novel mechanism of atorvastatin to protect mesenchymal stem cells from hypoxia and serum deprivation via AMP-Activated protein kinase/mammalian target of rapamycin pathway Stem Cells and Development 21 2012 1321 1332
-
(2012)
Stem Cells and Development
, vol.21
, pp. 1321-1332
-
-
Zhang, Q.1
Yang, Y.J.2
Wang, H.3
Dong, Q.T.4
Wang, T.J.5
Qian, H.Y.6
-
96
-
-
84860855996
-
Effects of atorvastatin on the autophagy of vascular endothelial cells
-
S. Zhang, L. Qiu, C. Xiao, Y. Fang, and Y. Li Effects of atorvastatin on the autophagy of vascular endothelial cells Journal of Shanxi Medical University 40 2009 404 407
-
(2009)
Journal of Shanxi Medical University
, vol.40
, pp. 404-407
-
-
Zhang, S.1
Qiu, L.2
Xiao, C.3
Fang, Y.4
Li, Y.5
-
97
-
-
4143118857
-
Inverted signaling hierarchy between RAS and RAC in T-lymphocytes
-
J.L. Zugaza, M.J. Caloca, and X.R. Bustelo Inverted signaling hierarchy between RAS and RAC in T-lymphocytes Oncogene 23 2004 5823 5833
-
(2004)
Oncogene
, vol.23
, pp. 5823-5833
-
-
Zugaza, J.L.1
Caloca, M.J.2
Bustelo, X.R.3
|