-
3
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D. & Weinberg, R. A. The hallmarks of cancer. Cell 100, 57-70 (2000).
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
4
-
-
0024851534
-
trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development
-
Klein, R., Parada, L. F., Coulier, F. & Barbacid, M. trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development. EMBO J. 8, 3701-3709 (1989).
-
(1989)
EMBO J.
, vol.8
, pp. 3701-3709
-
-
Klein, R.1
Parada, L.F.2
Coulier, F.3
Barbacid, M.4
-
5
-
-
0041488911
-
Trk receptors: Roles in neuronal signal transduction
-
Huang, E. J. & Reichardt, L. F. Trk receptors: roles in neuronal signal transduction. Annu. Rev. Biochem. 72, 609-642 (2003).
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 609-642
-
-
Huang, E.J.1
Reichardt, L.F.2
-
6
-
-
0034725690
-
Oncogenic Ras-mediated cell growth arrest and apoptosis are associated with increased ubiquitin-dependent cyclin D1 degradation
-
Shao, J., Sheng, H., DuBois, R. N. & Beauchamp, R. D. Oncogenic Ras-mediated cell growth arrest and apoptosis are associated with increased ubiquitin-dependent cyclin D1 degradation. J. Biol. Chem. 275, 22916-22924 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 22916-22924
-
-
Shao, J.1
Sheng, H.2
DuBois, R.N.3
Beauchamp, R.D.4
-
7
-
-
0034928862
-
Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase
-
McFall, A. et al. Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase. Mol. Cell Biol. 21, 5488-5499 (2001).
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 5488-5499
-
-
McFall, A.1
-
8
-
-
0037114239
-
Novel retroviral vectors to facilitate expression screens in mammalian cells
-
Koh, E. Y., Chen, T. & Daley, G. Q. Novel retroviral vectors to facilitate expression screens in mammalian cells. Nucleic Acids Res. 30, e142 (2002).
-
(2002)
Nucleic Acids Res.
, vol.30
-
-
Koh, E.Y.1
Chen, T.2
Daley, G.Q.3
-
9
-
-
0025896342
-
TrkB mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low affinity NGF receptor
-
Glass, D. J. et al. TrkB mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low affinity NGF receptor. Cell 66, 405-413 (1991).
-
(1991)
Cell
, vol.66
, pp. 405-413
-
-
Glass, D.J.1
-
10
-
-
0037430992
-
Cisplatin-induced cytotoxicity is blocked by brain-derived neurotrophic factor activation of TrkB signal transduction path in neuroblastoma
-
Jaboin, J., Hong, A., Kim, C. J. & Thiele, C. J. Cisplatin-induced cytotoxicity is blocked by brain-derived neurotrophic factor activation of TrkB signal transduction path in neuroblastoma. Cancer Lett. 193, 109-114 (2003).
-
(2003)
Cancer Lett.
, vol.193
, pp. 109-114
-
-
Jaboin, J.1
Hong, A.2
Kim, C.J.3
Thiele, C.J.4
-
11
-
-
0037112433
-
Resistance to chemotherapy mediated by TrkB in neuroblastomas
-
Ho, R. et al. Resistance to chemotherapy mediated by TrkB in neuroblastomas. Cancer Res. 62, 6462-6466 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 6462-6466
-
-
Ho, R.1
-
12
-
-
0027491104
-
Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death
-
Klein, R. et al. Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death. Cell 75, 113-122 (1993).
-
(1993)
Cell
, vol.75
, pp. 113-122
-
-
Klein, R.1
-
13
-
-
0036357241
-
Elucidating the molecular mechanisms that underlie the target control of motoneuron death
-
Banks, G. B. & Noakes, P. G. Elucidating the molecular mechanisms that underlie the target control of motoneuron death. Int. J. Dev. Biol. 46, 551-558 (2002).
-
(2002)
Int. J. Dev. Biol.
, vol.46
, pp. 551-558
-
-
Banks, G.B.1
Noakes, P.G.2
-
14
-
-
0025827738
-
The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor
-
Soppet, D. et al. The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor. Cell 65, 895-903 (1991).
-
(1991)
Cell
, vol.65
, pp. 895-903
-
-
Soppet, D.1
-
15
-
-
0025731382
-
trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor
-
Squinto, S. P. et al. trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor. Cell 65, 885-893 (1991).
-
(1991)
Cell
, vol.65
, pp. 885-893
-
-
Squinto, S.P.1
-
16
-
-
0031252506
-
Cell-to-cell contact and extracellular matrix
-
Ruoslahti, E. & Vaheri, A. Cell-to-cell contact and extracellular matrix. Curr. Opin. Cell Biol. 9, 605-607 (1997).
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 605-607
-
-
Ruoslahti, E.1
Vaheri, A.2
-
17
-
-
0042696985
-
Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis
-
Reginato, M. J. et al. Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Nature Cell Biol. 5, 733-740 (2003).
-
(2003)
Nature Cell Biol.
, vol.5
, pp. 733-740
-
-
Reginato, M.J.1
-
18
-
-
0030913673
-
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
-
Khwaja, A., Rodriguez-Viciana, P., Wennstrom, S., Warne, P. H. & Downward, J. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J. 16, 2783-2793 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 2783-2793
-
-
Khwaja, A.1
Rodriguez-Viciana, P.2
Wennstrom, S.3
Warne, P.H.4
Downward, J.5
-
19
-
-
0037037374
-
A novel form of constitutively active farnesylated Akt1 prevents mammary epithelial cells from anoikis and suppresses chemotherapy-induced apoptosis
-
Schmidt, M., Hovelmann, S. & Beckers, T. L. A novel form of constitutively active farnesylated Akt1 prevents mammary epithelial cells from anoikis and suppresses chemotherapy-induced apoptosis. Br. J. Cancer 87, 924-932 (2002).
-
(2002)
Br. J. Cancer
, vol.87
, pp. 924-932
-
-
Schmidt, M.1
Hovelmann, S.2
Beckers, T.L.3
-
20
-
-
1642586272
-
Survival signalling by Akt and eIF 4E in oncogenesis and cancer therapy
-
Wendel, H. G. et al. Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. Nature 428, 332-337 (2004).
-
(2004)
Nature
, vol.428
, pp. 332-337
-
-
Wendel, H.G.1
-
21
-
-
0037086089
-
Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumours in mice
-
Vooijs, M., Jonkers, J., Lyons, S. & Berns, A. Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumours in mice. Cancer Res. 62, 1862-1867 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 1862-1867
-
-
Vooijs, M.1
Jonkers, J.2
Lyons, S.3
Berns, A.4
-
22
-
-
0028107269
-
Expression and function of TRK-B and BDNF in human neuroblastomas
-
Nakagawara, A., Azar, C. G., Scavarda, N. J. & Brodeur, G. M. Expression and function of TRK-B and BDNF in human neuroblastomas. Mol. Cell Biol. 14, 759-767 (1994).
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 759-767
-
-
Nakagawara, A.1
Azar, C.G.2
Scavarda, N.J.3
Brodeur, G.M.4
-
23
-
-
0035836071
-
Human neuroblastomas with unfavorable biologies express high levels of brain-derived neurotrophic factor mRNA and a variety of its variants
-
Aoyama, M. et al. Human neuroblastomas with unfavorable biologies express high levels of brain-derived neurotrophic factor mRNA and a variety of its variants. Cancer Lett. 164, 51-60 (2001).
-
(2001)
Cancer Lett.
, vol.164
, pp. 51-60
-
-
Aoyama, M.1
-
24
-
-
0035253655
-
Expression of the neurotrophin receptor TrkB is associated with unfavorable outcome in Wilms' tumor
-
Eggert, A. et al. Expression of the neurotrophin receptor TrkB is associated with unfavorable outcome in Wilms' tumor. J. Clin. Oncol. 19, 689-696 (2001).
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 689-696
-
-
Eggert, A.1
-
25
-
-
0037366067
-
Neuroblastoma: Biological insights into a clinical enigma
-
Brodeur, G. M. Neuroblastoma: biological insights into a clinical enigma. Nature Rev. Cancer 3, 203-216 (2003).
-
(2003)
Nature Rev. Cancer
, vol.3
, pp. 203-216
-
-
Brodeur, G.M.1
-
26
-
-
0038670241
-
Mutational analysis of the tyrosine kinome in colorectal cancers
-
Bardelli, A. et al. Mutational analysis of the tyrosine kinome in colorectal cancers. Science 300, 949 (2003).
-
(2003)
Science
, vol.300
, pp. 949
-
-
Bardelli, A.1
-
27
-
-
0037158692
-
A progression puzzle
-
Bernards, R. & Weinberg, R. A. A progression puzzle. Nature 418, 823 (2002).
-
(2002)
Nature
, vol.418
, pp. 823
-
-
Bernards, R.1
Weinberg, R.A.2
-
28
-
-
0032877546
-
Role of neurotrophin-trk interactions in oncology: The anti-tumor efficacy of potent and selective trk tyrosine kinase inhibitors in pre-clinical tumor models
-
Ruggeri, B. A., Miknyoczki, S. J., Singh, J. & Hudkins, R. L. Role of neurotrophin-trk interactions in oncology: the anti-tumor efficacy of potent and selective trk tyrosine kinase inhibitors in pre-clinical tumor models. Curr. Med. Chem. 6, 845-857 (1999).
-
(1999)
Curr. Med. Chem.
, vol.6
, pp. 845-857
-
-
Ruggeri, B.A.1
Miknyoczki, S.J.2
Singh, J.3
Hudkins, R.L.4
-
29
-
-
0036167650
-
A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence
-
Peeper, D. S. et al. A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence. Nature Cell Biol. 4, 148-153 (2002).
-
(2002)
Nature Cell Biol.
, vol.4
, pp. 148-153
-
-
Peeper, D.S.1
-
30
-
-
0029862706
-
Mitochondrial control of nuclear apoptosis
-
Zamzami, N. et al. Mitochondrial control of nuclear apoptosis. J. Exp. Med. 183, 1533-1544 (1996).
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1533-1544
-
-
Zamzami, N.1
|