-
1
-
-
0029805324
-
Regulation of phosphorylation pathways by p21 GTPases-The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways
-
L. Lim, E. Manser, T. Leung, and C. Hall Regulation of phosphorylation pathways by p21 GTPases-The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways Eur. J. Biochem. 242 1996 171 185
-
(1996)
Eur. J. Biochem.
, vol.242
, pp. 171-185
-
-
Lim, L.1
Manser, E.2
Leung, T.3
Hall, C.4
-
2
-
-
0030968580
-
Rho GTPases and signaling networks
-
L. Van Aelst, and C. D'Souza-Schorey Rho GTPases and signaling networks Genes Dev. 11 1997 2295 2322
-
(1997)
Genes Dev.
, vol.11
, pp. 2295-2322
-
-
Van Aelst, L.1
D'Souza-Schorey, C.2
-
3
-
-
0029898894
-
Protein prenylation: Molecular mechanisms and functional consequences
-
F.L. Zhang, and P.J. Casey Protein prenylation: molecular mechanisms and functional consequences Annu. Rev. Biochem. 65 1996 241 269
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 241-269
-
-
Zhang, F.L.1
Casey, P.J.2
-
4
-
-
0029894664
-
Identification of a novel human rho protein with unusual properties: GTPase deficiency and in vivo farnesylation
-
R. Foster, K.Q. Hu, Y. Lu, K.M. Nolan, J. Thissen, and J. Settleman Identification of a novel human rho protein with unusual properties: GTPase deficiency and in vivo farnesylation Mol. Cell. Biol. 16 1996 2689 2699
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2689-2699
-
-
Foster, R.1
Hu, K.Q.2
Lu, Y.3
Nolan, K.M.4
Thissen, J.5
Settleman, J.6
-
5
-
-
0026001936
-
A protein geranylgeranyltransferase from bovine brain: Implications for protein prenylation specificity
-
K. Yokoyama, G.W. Goodwin, F. Ghomashchi, J.A. Glomset, and M.H. Gelb A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity Proc. Natl. Acad. Sci. U. S. A. 88 1991 5302 5306
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 5302-5306
-
-
Yokoyama, K.1
Goodwin, G.W.2
Ghomashchi, F.3
Glomset, J.A.4
Gelb, M.H.5
-
6
-
-
0027416643
-
Purification of a mammalian protein geranylgeranyltransferase-Formation and catalytic properties of an enzyme-geranylgeranyl pyrophosphate complex
-
K. Yokoyama, and M.H. Gelb Purification of a mammalian protein geranylgeranyltransferase-Formation and catalytic properties of an enzyme-geranylgeranyl pyrophosphate complex J. Biol. Chem. 268 1993 4055 4060
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 4055-4060
-
-
Yokoyama, K.1
Gelb, M.H.2
-
8
-
-
0030916369
-
Farnesyltransferase inhibitors alter the prenylation and growth-stimulating function of RhoB
-
P.F. Lebowitz, P.J. Casey, G.C. Prendergast, and J.A. Thissen Farnesyltransferase inhibitors alter the prenylation and growth-stimulating function of RhoB J. Biol. Chem. 272 1997 15591 15594
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 15591-15594
-
-
Lebowitz, P.F.1
Casey, P.J.2
Prendergast, G.C.3
Thissen, J.A.4
-
9
-
-
0034633651
-
RhoB prenylation is driven by the three carboxyl-terminal amino acids of the protein: Evidenced in vivo by an anti-farnesyl cysteine antibody
-
R. Baron, E. Fourcade, I. Lajoie-Mazenc, C. Allal, B. Couderc, R. Barbaras, G. Favre, J.C. Faye, and A. Pradines RhoB prenylation is driven by the three carboxyl-terminal amino acids of the protein: evidenced in vivo by an anti-farnesyl cysteine antibody Proc. Natl. Acad. Sci. U. S. A. 97 2000 11626 11631
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 11626-11631
-
-
Baron, R.1
Fourcade, E.2
Lajoie-Mazenc, I.3
Allal, C.4
Couderc, B.5
Barbaras, R.6
Favre, G.7
Faye, J.C.8
Pradines, A.9
-
10
-
-
0028933716
-
Ultrastructural localization of ras-related proteins using epitope-tagged plasmids
-
D. Robertson, H.F. Paterson, P. Adamson, A. Hall, and P. Monaghan Ultrastructural localization of ras-related proteins using epitope-tagged plasmids J. Histochem. Cytochem. 43 1995 471 480
-
(1995)
J. Histochem. Cytochem.
, vol.43
, pp. 471-480
-
-
Robertson, D.1
Paterson, H.F.2
Adamson, P.3
Hall, A.4
Monaghan, P.5
-
11
-
-
0026612457
-
Intracellular localization of the p21Rho proteins
-
P. Adamson, H.F. Paterson, and A. Hall Intracellular localization of the p21Rho proteins J. Cell Biol. 119 1992 617 627
-
(1992)
J. Cell Biol.
, vol.119
, pp. 617-627
-
-
Adamson, P.1
Paterson, H.F.2
Hall, A.3
-
12
-
-
4344619948
-
Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase
-
M. Wherlock, A. Gampel, C. Futter, and H. Mellor Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase J. Cell Sci. 117 2004 3221 3231
-
(2004)
J. Cell Sci.
, vol.117
, pp. 3221-3231
-
-
Wherlock, M.1
Gampel, A.2
Futter, C.3
Mellor, H.4
-
13
-
-
0035825193
-
Differential localization of Rho GTPases in live cells. Regulation by hypervariable regions and rhogdi binding
-
D. Michaelson, J. Silletti, G. Murphy, P. D'Eustachio, M. Rush, and M.R. Philips Differential localization of Rho GTPases in live cells. Regulation by hypervariable regions and rhogdi binding J. Cell Biol. 152 2001 111 126
-
(2001)
J. Cell Biol.
, vol.152
, pp. 111-126
-
-
Michaelson, D.1
Silletti, J.2
Murphy, G.3
D'Eustachio, P.4
Rush, M.5
Philips, M.R.6
-
14
-
-
0032540280
-
RhoB is stabilized by TGFβ and antagonizes transcriptional activation
-
M.E. Engel, P.K. Datta, and H.L. Moses RhoB is stabilized by TGFβ and antagonizes transcriptional activation J. Biol. Chem. 273 1998 9921 9926
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9921-9926
-
-
Engel, M.E.1
Datta, P.K.2
Moses, H.L.3
-
15
-
-
0028998476
-
Regulation of ras-related RhoB protein expression during the cell cycle
-
G. Zalcman, V. Closson, G. Linarescruz, F. Lerebours, N. Honore, A. Tavitian, and B. Olofsson Regulation of ras-related RhoB protein expression during the cell cycle Oncogene 10 1995 1935 1945
-
(1995)
Oncogene
, vol.10
, pp. 1935-1945
-
-
Zalcman, G.1
Closson, V.2
Linarescruz, G.3
Lerebours, F.4
Honore, N.5
Tavitian, A.6
Olofsson, B.7
-
16
-
-
0028072995
-
EGF modulation of the ras-related rhoB gene expression in human breast-cancer cell lines
-
P. De Cremoux, C. Gauville, V. Closson, G. Linares, F. Calvo, A. Tavitian, and B. Olofsson EGF modulation of the ras-related rhoB gene expression in human breast-cancer cell lines Int. J. Cancer 59 1994 408 415
-
(1994)
Int. J. Cancer
, vol.59
, pp. 408-415
-
-
De Cremoux, P.1
Gauville, C.2
Closson, V.3
Linares, G.4
Calvo, F.5
Tavitian, A.6
Olofsson, B.7
-
17
-
-
0032945213
-
Regulation of actin organisation by TGF-beta in H-ras-transformed fibroblasts
-
A. Moustakas, and C. Stournaras Regulation of actin organisation by TGF-beta in H-ras-transformed fibroblasts J. Cell Sci. 112 1999 1169 1179
-
(1999)
J. Cell Sci.
, vol.112
, pp. 1169-1179
-
-
Moustakas, A.1
Stournaras, C.2
-
18
-
-
0028849261
-
The ras-related small GTP-binding protein RhoB is immediate-early inducible by DNA damaging treatments
-
G. Fritz, B. Kaina, and K. Aktories The ras-related small GTP-binding protein RhoB is immediate-early inducible by DNA damaging treatments J. Biol. Chem. 270 1995 25172 25177
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25172-25177
-
-
Fritz, G.1
Kaina, B.2
Aktories, K.3
-
19
-
-
0025831433
-
The ras-related gene rhoB is an immediate-early gene inducible by v-Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts
-
D. Jahner, and T. Hunter The ras-related gene rhoB is an immediate-early gene inducible by v-Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts Mol. Cell. Biol. 11 1991 3682 3690
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 3682-3690
-
-
Jahner, D.1
Hunter, T.2
-
20
-
-
0028892646
-
Evidence that farnesyltransferase inhibitors suppress ras transformation by interfering with rho activity
-
P.F. Lebowitz, J.P. Davide, and G.C. Prendergast Evidence that farnesyltransferase inhibitors suppress ras transformation by interfering with rho activity Mol. Cell. Biol. 15 1995 6613 6622
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6613-6622
-
-
Lebowitz, P.F.1
Davide, J.P.2
Prendergast, G.C.3
-
21
-
-
0032541650
-
Increasing complexity of Ras signaling
-
S.L. Campbell, R. KhosraviFar, K.L. Rossman, G.J. Clark, and C.J. Der Increasing complexity of Ras signaling Oncogene 17 1998 1395 1413
-
(1998)
Oncogene
, vol.17
, pp. 1395-1413
-
-
Campbell, S.L.1
Khosravifar, R.2
Rossman, K.L.3
Clark, G.J.4
Der, C.J.5
-
22
-
-
0032541613
-
Rho family proteins and Ras transformation: The RHOad less traveled gets congested
-
I.M. Zohn, S.L. Campbell, R. KhosraviFar, K.L. Rossman, and C.J. Der Rho family proteins and Ras transformation: the RHOad less traveled gets congested Oncogene 17 1998 1415 1438
-
(1998)
Oncogene
, vol.17
, pp. 1415-1438
-
-
Zohn, I.M.1
Campbell, S.L.2
Khosravifar, R.3
Rossman, K.L.4
Der, C.J.5
-
23
-
-
0033539150
-
Regulation of epidermal growth factor receptor traffic by the small GTPase rhoB
-
A. Gampel, P.J. Parker, and H. Mellor Regulation of epidermal growth factor receptor traffic by the small GTPase rhoB Curr. Biol. 9 1999 955 958
-
(1999)
Curr. Biol.
, vol.9
, pp. 955-958
-
-
Gampel, A.1
Parker, P.J.2
Mellor, H.3
-
24
-
-
0034708159
-
Ras-related GTPase RhoB forces alkylation-induced apoptotic cell death
-
G. Fritz, and B. Kaina Ras-related GTPase RhoB forces alkylation-induced apoptotic cell death Biochem. Biophys. Res. Commun. 268 2000 784 789
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.268
, pp. 784-789
-
-
Fritz, G.1
Kaina, B.2
-
26
-
-
0031034469
-
Activation of the nuclear factor-kB by Rho, CDC42, and Rac-1 proteins
-
R. Perona, S. Montaner, L. Saniger, I. Sanchez-Perez, R. Bravo, and J.C. Lacal Activation of the nuclear factor-kB by Rho, CDC42, and Rac-1 proteins Genes Dev. 11 1997 463 475
-
(1997)
Genes Dev.
, vol.11
, pp. 463-475
-
-
Perona, R.1
Montaner, S.2
Saniger, L.3
Sanchez-Perez, I.4
Bravo, R.5
Lacal, J.C.6
-
27
-
-
0035793611
-
Ras-related GTPase RhoB represses NF-kB signaling
-
G. Fritz, and B. Kaina Ras-related GTPase RhoB represses NF-kB signaling J. Biol. Chem. 276 2001 3115 3122
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3115-3122
-
-
Fritz, G.1
Kaina, B.2
-
28
-
-
0029101360
-
An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1
-
M.F. Olson, A. Ashworth, and A. Hall An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1 Science 269 1995 1270 1272
-
(1995)
Science
, vol.269
, pp. 1270-1272
-
-
Olson, M.F.1
Ashworth, A.2
Hall, A.3
-
29
-
-
0027191250
-
Tumorigenic activity of rho genes from Aplysia californica
-
R. Perona, P. Esteve, B. Jimenez, R.P. Ballestero, S. Ramon y Cajal, and J.C. Lacal Tumorigenic activity of rho genes from Aplysia californica Oncogene 8 1993 1285 1292
-
(1993)
Oncogene
, vol.8
, pp. 1285-1292
-
-
Perona, R.1
Esteve, P.2
Jimenez, B.3
Ballestero, R.P.4
Ramon Cajal, Y.S.5
Lacal, J.C.6
-
30
-
-
0028800305
-
Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation
-
R. Khosravi-Far, P.A. Solski, G.J. Clark, M.S. Kinch, and C.J. Der Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation Mol. Cell. Biol. 15 1995 6443 6453
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6443-6453
-
-
Khosravi-Far, R.1
Solski, P.A.2
Clark, G.J.3
Kinch, M.S.4
Der, C.J.5
-
31
-
-
0028903247
-
An essential role for rac in ras transformation
-
R.G. Qiu, J. Chen, D. Kirn, F. Mccormick, and M. Symons An essential role for rac in ras transformation Nature 374 1995 457 459
-
(1995)
Nature
, vol.374
, pp. 457-459
-
-
Qiu, R.G.1
Chen, J.2
Kirn, D.3
McCormick, F.4
Symons, M.5
-
33
-
-
0030992814
-
Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation
-
R.G. Qiu, A. Abo, F. McCormick, and M. Symons Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation Mol. Cell. Biol. 17 1997 3449 3458
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3449-3458
-
-
Qiu, R.G.1
Abo, A.2
McCormick, F.3
Symons, M.4
-
34
-
-
0029057465
-
Critical role of rho in cell transformation by oncogenic ras
-
G.C. Prendergast, R. Khosravi-Far, P.A. Solski, H. Kurzawa, P.F. Lebowitz, and C.J. Der Critical role of rho in cell transformation by oncogenic ras Oncogene 10 1995 2289 2296
-
(1995)
Oncogene
, vol.10
, pp. 2289-2296
-
-
Prendergast, G.C.1
Khosravi-Far, R.2
Solski, P.A.3
Kurzawa, H.4
Lebowitz, P.F.5
Der, C.J.6
-
35
-
-
0030910236
-
Prenylation of RhoB is required for its cell transforming function but not its ability to activate serum response element-dependent transcription
-
P.F. Lebowitz, W. Du, and G.C. Prendergast Prenylation of RhoB is required for its cell transforming function but not its ability to activate serum response element-dependent transcription J. Biol. Chem. 272 1997 16093 16095
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16093-16095
-
-
Lebowitz, P.F.1
Du, W.2
Prendergast, G.C.3
-
36
-
-
0033231190
-
Geranylgeranylated RhoB mediates suppression of human tumor cell growth by farnesyltransferase inhibitors
-
W. Du, and G.C. Prendergast Geranylgeranylated RhoB mediates suppression of human tumor cell growth by farnesyltransferase inhibitors Cancer Res. 59 1999 5492 5496
-
(1999)
Cancer Res.
, vol.59
, pp. 5492-5496
-
-
Du, W.1
Prendergast, G.C.2
-
37
-
-
0034674417
-
Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation, induce apoptosis and suppress human tumor growth in nude mice
-
Z. Chen, J. Sun, A. Pradines, G. Favre, J. Adnane, and S.M. Sebti Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation, induce apoptosis and suppress human tumor growth in nude mice J. Biol. Chem. 275 2000 17974 17978
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17974-17978
-
-
Chen, Z.1
Sun, J.2
Pradines, A.3
Favre, G.4
Adnane, J.5
Sebti, S.M.6
-
38
-
-
0035992372
-
Suppression of rho B expression in invasive carcinoma from head and neck cancer patients
-
J. Adnane, C. Muro-Cacho, L. Mathews, S.M. Sebti, and T. Munoz-Antonia Suppression of rho B expression in invasive carcinoma from head and neck cancer patients Clin. Cancer Res. 8 2002 2225 2232
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 2225-2232
-
-
Adnane, J.1
Muro-Cacho, C.2
Mathews, L.3
Sebti, S.M.4
Munoz-Antonia, T.5
-
39
-
-
1942502372
-
Loss of RhoB expression in human lung cancer progression
-
J. Mazieres, T. Antonia, G. Daste, C. Muro-Cacho, D. Berchery, V. Tillement, A. Pradines, S. Sebti, and G. Favre Loss of RhoB expression in human lung cancer progression Clin. Cancer Res. 10 2004 2742 2750
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 2742-2750
-
-
Mazieres, J.1
Antonia, T.2
Daste, G.3
Muro-Cacho, C.4
Berchery, D.5
Tillement, V.6
Pradines, A.7
Sebti, S.8
Favre, G.9
-
40
-
-
1442352096
-
EGFR, ErbB2 and Ras but not Src suppress RhoB expression while ectopic expression of RhoB antagonizes oncogene-mediated transformation
-
K. Jiang, F.L. Delarue, and S.M. Sebti EGFR, ErbB2 and Ras but not Src suppress RhoB expression while ectopic expression of RhoB antagonizes oncogene-mediated transformation Oncogene 23 2004 1136 1145
-
(2004)
Oncogene
, vol.23
, pp. 1136-1145
-
-
Jiang, K.1
Delarue, F.L.2
Sebti, S.M.3
-
41
-
-
0033016719
-
Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated RhoB
-
W. Du, P.F. Lebowitz, and G.C. Prendergast Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated RhoB Mol. Cell. Biol. 19 1999 1831 1840
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 1831-1840
-
-
Du, W.1
Lebowitz, P.F.2
Prendergast, G.C.3
-
42
-
-
0031038148
-
Improved oligonucleotide uptake and stability by a new drug carrier, the SupraMolecular Bio Vector (SMBV)
-
M. Berton, S. Sixou, R. Kravtzoff, C. Dartigues, L. Imbertie, C. Allal, and G. Favre Improved oligonucleotide uptake and stability by a new drug carrier, the SupraMolecular Bio Vector (SMBV) Biochim. Biophys. Acta 1355 1997 7 19
-
(1997)
Biochim. Biophys. Acta
, vol.1355
, pp. 7-19
-
-
Berton, M.1
Sixou, S.2
Kravtzoff, R.3
Dartigues, C.4
Imbertie, L.5
Allal, C.6
Favre, G.7
-
43
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer drug screening
-
P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. McMahon, D. Vistica, J.T. Warren, H. Bokesch, S. Kenney, and M.R. Boyd New colorimetric cytotoxicity assay for anticancer drug screening J. Natl. Cancer Inst. 82 1990 1107 1112
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
Vistica, D.6
Warren, J.T.7
Bokesch, H.8
Kenney, S.9
Boyd, M.R.10
-
44
-
-
0030952552
-
Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitors in human tumor cell lines
-
E.A. Lerner, T.-T. Zhang, D.B. Knowles, Y. Qian, A.D. Hamilton, and S.M. Sebti Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitors in human tumor cell lines Oncogene 15 1997 1283 1288
-
(1997)
Oncogene
, vol.15
, pp. 1283-1288
-
-
Lerner, E.A.1
Zhang, T.-T.2
Knowles, D.B.3
Qian, Y.4
Hamilton, A.D.5
Sebti, S.M.6
-
45
-
-
0032489443
-
Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane
-
T. Okamoto, A. Schlegel, P.E. Scherer, and M.P. Lisanti Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane J. Biol. Chem. 273 1998 5419 5422
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5419-5422
-
-
Okamoto, T.1
Schlegel, A.2
Scherer, P.E.3
Lisanti, M.P.4
-
47
-
-
0344867849
-
Reduction of caveolin 1 gene expression in lung carcinoma cell lines
-
C. Racine, M. Belanger, H. Hirabayashi, M. Boucher, J. Chakir, and J. Couet Reduction of caveolin 1 gene expression in lung carcinoma cell lines Biochem. Biophys. Res. Commun. 255 1999 580 586
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.255
, pp. 580-586
-
-
Racine, C.1
Belanger, M.2
Hirabayashi, H.3
Boucher, M.4
Chakir, J.5
Couet, J.6
-
48
-
-
0036709020
-
Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling
-
J. Pouyssegur, V. Volmat, and P. Lenormand Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling Biochem. Pharmacol. 64 2002 755 763
-
(2002)
Biochem. Pharmacol.
, vol.64
, pp. 755-763
-
-
Pouyssegur, J.1
Volmat, V.2
Lenormand, P.3
-
49
-
-
0034808219
-
RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells
-
A.X. Liu, N. Rane, J.P. Liu, and G.C. Prendergast RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells Mol. Cell. Biol. 21 2001 6906 6912
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6906-6912
-
-
Liu, A.X.1
Rane, N.2
Liu, J.P.3
Prendergast, G.C.4
-
50
-
-
0029890896
-
Oncogenic ras activation of raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation
-
R. Khosravi-Far, M.A. White, J.K. Westwick, P.A. Solski, M. Chrzanowskawodnicka, L. Vanaelst, M.H. Wigler, and C.J. Der Oncogenic ras activation of raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation Mol. Cell. Biol. 16 1996 3923 3933
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3923-3933
-
-
Khosravi-Far, R.1
White, M.A.2
Westwick, J.K.3
Solski, P.A.4
Chrzanowskawodnicka, M.5
Vanaelst, L.6
Wigler, M.H.7
Der, C.J.8
-
51
-
-
0034703471
-
Geranylgeranylated RhoB is sufficient to mediate tissue-specific suppression of Akt kinase activity by farnesyltransferase inhibitors
-
A. Liu, and G.C. Prendergast Geranylgeranylated RhoB is sufficient to mediate tissue-specific suppression of Akt kinase activity by farnesyltransferase inhibitors FEBS Lett. 481 2000 205 208
-
(2000)
FEBS Lett.
, vol.481
, pp. 205-208
-
-
Liu, A.1
Prendergast, G.C.2
-
52
-
-
0033860183
-
RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors
-
A. Liu, W. Du, J.P. Liu, T.M. Jessell, and G.C. Prendergast RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors Mol. Cell. Biol. 20 2000 6105 6113
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 6105-6113
-
-
Liu, A.1
Du, W.2
Liu, J.P.3
Jessell, T.M.4
Prendergast, G.C.5
-
53
-
-
0242266953
-
RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development
-
I. Adini, I. Rabinovitz, J.F. Sun, G.C. Prendergast, and L.E. Benjamin RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development Genes Dev. 17 2003 2721 2732
-
(2003)
Genes Dev.
, vol.17
, pp. 2721-2732
-
-
Adini, I.1
Rabinovitz, I.2
Sun, J.F.3
Prendergast, G.C.4
Benjamin, L.E.5
-
54
-
-
0029858387
-
TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
-
C.Y. Wang, M.W. Mayo, and A.S. Baldwin Jr. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB Science 274 1996 784 787
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin Jr., A.S.3
-
55
-
-
0034982061
-
GTPase RhoB: An early predictor of neuronal death after transient focal ischemia in mice
-
T. Trapp, L. Olah, I. Holker, M. Besselmann, C. Tiesler, K. Maeda, and K.A. Hossmann GTPase RhoB: an early predictor of neuronal death after transient focal ischemia in mice Mol. Cell. Neurosci. 17 2001 883 894
-
(2001)
Mol. Cell. Neurosci.
, vol.17
, pp. 883-894
-
-
Trapp, T.1
Olah, L.2
Holker, I.3
Besselmann, M.4
Tiesler, C.5
Maeda, K.6
Hossmann, K.A.7
-
56
-
-
85047689142
-
RhoB and the cellular response to farnesyltransferase inhibitors: The search for clues to cell death mechanisms
-
E.J. Bernhard RhoB and the cellular response to farnesyltransferase inhibitors: the search for clues to cell death mechanisms Cancer Biol. Ther. 2 2003 281 282
-
(2003)
Cancer Biol. Ther.
, vol.2
, pp. 281-282
-
-
Bernhard, E.J.1
-
57
-
-
2942628062
-
Akt mediates Ras downregulation of RhoB, a suppressor of transformation, invasion, and metastasis
-
K. Jiang, J. Sun, J. Cheng, J.Y. Djeu, S. Wei, and S. Sebti Akt mediates Ras downregulation of RhoB, a suppressor of transformation, invasion, and metastasis Mol. Cell. Biol. 24 2004 5565 5576
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 5565-5576
-
-
Jiang, K.1
Sun, J.2
Cheng, J.3
Djeu, J.Y.4
Wei, S.5
Sebti, S.6
-
58
-
-
0037468252
-
Role for RhoB and PRK in the suppression of epithelial cell transformation by farnesyltransferase inhibitors
-
P.Y. Zeng, N. Rane, W. Du, J. Chintapalli, and G.C. Prendergast Role for RhoB and PRK in the suppression of epithelial cell transformation by farnesyltransferase inhibitors Oncogene 22 2003 1124 1134
-
(2003)
Oncogene
, vol.22
, pp. 1124-1134
-
-
Zeng, P.Y.1
Rane, N.2
Du, W.3
Chintapalli, J.4
Prendergast, G.C.5
-
59
-
-
0034646677
-
Rho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinase
-
P. Flynn, H. Mellor, A. Casamassima, and P.J. Parker Rho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide- dependent protein kinase J. Biol. Chem. 275 2000 11064 11070
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 11064-11070
-
-
Flynn, P.1
Mellor, H.2
Casamassima, A.3
Parker, P.J.4
-
60
-
-
0034704141
-
Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1
-
M.J. Wick, L.Q. Dong, R.A. Riojas, F.J. Ramos, and F. Liu Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1 J. Biol. Chem. 275 2000 40400 40406
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40400-40406
-
-
Wick, M.J.1
Dong, L.Q.2
Riojas, R.A.3
Ramos, F.J.4
Liu, F.5
-
61
-
-
0033523091
-
Role of isoprenoid lipids on the heterotrimeric G protein gamma subunit in determining effector activation
-
C.S. Myung, H. Yasuda, W.W. Liu, T.K. Harden, and J.C. Garrison Role of isoprenoid lipids on the heterotrimeric G protein gamma subunit in determining effector activation J. Biol. Chem. 274 1999 16595 16603
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 16595-16603
-
-
Myung, C.S.1
Yasuda, H.2
Liu, W.W.3
Harden, T.K.4
Garrison, J.C.5
-
62
-
-
0035930546
-
G beta gamma affinity for bovine rhodopsin is determined by the carboxyl-terminal sequences of the gamma subunit
-
X. Jian, W.A. Clark, J. Kowalak, S.P. Markey, W.F. Simonds, and J.K. Northup G beta gamma affinity for bovine rhodopsin is determined by the carboxyl-terminal sequences of the gamma subunit J. Biol. Chem. 276 2001 48518 48525
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48518-48525
-
-
Jian, X.1
Clark, W.A.2
Kowalak, J.3
Markey, S.P.4
Simonds, W.F.5
Northup, J.K.6
-
63
-
-
0027998986
-
The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation
-
A.D. Cox, A.M. Garcia, J.K. Westwick, J.J. Kowalczyk, M.D. Lewis, D.A. Brenner, and C.J. Der The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation J. Biol. Chem. 269 1994 19203 19206
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 19203-19206
-
-
Cox, A.D.1
Garcia, A.M.2
Westwick, J.K.3
Kowalczyk, J.J.4
Lewis, M.D.5
Brenner, D.A.6
Der, C.J.7
-
64
-
-
0034613286
-
RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription
-
C. Allal, G. Favre, B. Couderc, S. Salicio, S. Sixou, A.D. Hamilton, S.M. Sebti, I. Lajoie-Mazenc, and A. Pradines RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription J. Biol. Chem. 275 2000 31001 31008
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31001-31008
-
-
Allal, C.1
Favre, G.2
Couderc, B.3
Salicio, S.4
Sixou, S.5
Hamilton, A.D.6
Sebti, S.M.7
Lajoie-Mazenc, I.8
Pradines, A.9
|