Atorvastatin induces autophagy in prostate cancer PC3 cells through activation of LC3 transcription

Cancer Biology and Therapy

Volumn 12, Issue 8, 2011, Pages 691-699

  Toepfer, Nicholas ^a   Childress, Chandra ^b   Parikh, Ankur ^a   Rukstalis, Daniel ^a   Yang, Wannian ^b  

^a GEISINGER MEDICAL CENTER   (United States)

^b WEIS CENTER FOR RESEARCH   (United States)

Author keywords

Autophagy; Erk; Geranylgeranyl; JNK; LC3; Prostate cancer; Statin

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ATORVASTATIN; GERANYLGERANIOL; GGTI 298; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE;

ARTICLE; AUTOPHAGY; BIOSYNTHESIS; CANCER CELL CULTURE; DRUG MECHANISM; GENE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LC3 GENE; POLYMERASE CHAIN REACTION; PROSTATE CANCER; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AUTOPHAGY; CELL GROWTH PROCESSES; DITERPENES; HEK293 CELLS; HEPTANOIC ACIDS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; MAP KINASE SIGNALING SYSTEM; MICROTUBULE-ASSOCIATED PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PROSTATIC NEOPLASMS; PYRROLES; TOR SERINE-THREONINE KINASES; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 80054105509     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.12.8.15978     Document Type: Article

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