Simvastatin alleviates the progression of periapical lesions by modulating autophagy and apoptosis in osteoblasts

Journal of Endodontics

Volumn 38, Issue 6, 2012, Pages 757-763

  Lai, Eddie Hsiang Hua ^a,b   Hong, Chi Yuan ^a,b   Kok, Sang Heng ^a,b   Hou, Kuo Liang ^a   Chao, Ling Hsiu ^a   Lin, Li Deh ^a,b   Chen, Mu Hsiung ^b   Wu, Ping Han ^c   Lin, Sze Kwan ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c TAIPEI CITY HOSPITAL   (Taiwan)

Author keywords

Apoptosis; autophagy; murine osteoblastic cells; periapical lesions; simvastatin

Indexed keywords

ANTIINFLAMMATORY AGENT; HYDROGEN PEROXIDE; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, MOUSE; SIMVASTATIN;

ANIMAL; APOPTOSIS; ARTICLE; AUTOPHAGY; BIOSYNTHESIS; CELL STRAIN 3T3; DRUG EFFECT; METABOLISM; MOUSE; NICK END LABELING; OSTEOBLAST; RAT; TOOTH PERIAPICAL DISEASE;

3T3 CELLS; ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; AUTOPHAGY; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; MICE; MICROTUBULE-ASSOCIATED PROTEINS; OSTEOBLASTS; PERIAPICAL PERIODONTITIS; POLY(ADP-RIBOSE) POLYMERASES; RATS; SIMVASTATIN;

EID: 84861198406     PISSN: 00992399     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joen.2012.02.023     Document Type: Article

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