-
1
-
-
84856487711
-
Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010
-
K.M. Flegal, M.D. Carroll, B.K. Kit, and C.L. Ogden Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010 JAMA 307 2012 491 497
-
(2012)
JAMA
, vol.307
, pp. 491-497
-
-
Flegal, K.M.1
Carroll, M.D.2
Kit, B.K.3
Ogden, C.L.4
-
3
-
-
0142093526
-
Fatty acid metabolism and insulin secretion in pancreatic beta cells
-
G.C. Yaney, and B.E. Corkey Fatty acid metabolism and insulin secretion in pancreatic beta cells Diabetologia 46 2003 1297 1312
-
(2003)
Diabetologia
, vol.46
, pp. 1297-1312
-
-
Yaney, G.C.1
Corkey, B.E.2
-
4
-
-
39749122734
-
The opposing effects of n-3 and n-6 fatty acids
-
G. Schmitz, and J. Ecker The opposing effects of n-3 and n-6 fatty acids Prog Lipid Res 47 2008 147 155
-
(2008)
Prog Lipid Res
, vol.47
, pp. 147-155
-
-
Schmitz, G.1
Ecker, J.2
-
5
-
-
0035976638
-
Nuclear receptors and lipid physiology: Opening the X-files
-
A. Chawla, J.J. Repa, R.M. Evans, and D.J. Mangelsdorf Nuclear receptors and lipid physiology: opening the X-files Science 294 2001 1866 1870
-
(2001)
Science
, vol.294
, pp. 1866-1870
-
-
Chawla, A.1
Repa, J.J.2
Evans, R.M.3
Mangelsdorf, D.J.4
-
6
-
-
0034665566
-
Mechanism for the antitumor and anticachectic effects of n-3 fatty acids
-
L.A. Sauer, R.T. Dauchy, and D.E. Blask Mechanism for the antitumor and anticachectic effects of n-3 fatty acids Cancer Res 60 2000 5289 5295
-
(2000)
Cancer Res
, vol.60
, pp. 5289-5295
-
-
Sauer, L.A.1
Dauchy, R.T.2
Blask, D.E.3
-
7
-
-
0035865496
-
Long-chain fatty acids regulate liver carnitine palmitoyltransferase i gene (L-CPT I) expression through a peroxisome-proliferator-activated receptor α (PPARα)-independent pathway
-
J.F. Louet, F. Chatelain, J.F. Decaux, E.A. Park, C. Kohl, and T. Pineau Long-chain fatty acids regulate liver carnitine palmitoyltransferase I gene (L-CPT I) expression through a peroxisome-proliferator-activated receptor α (PPARα)-independent pathway Biochem J 354 2001 189 197
-
(2001)
Biochem J
, vol.354
, pp. 189-197
-
-
Louet, J.F.1
Chatelain, F.2
Decaux, J.F.3
Park, E.A.4
Kohl, C.5
Pineau, T.6
-
8
-
-
0242710648
-
Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives
-
R. Fredriksson, P.J. Hoglund, D.E.I. Gloriam, M.C. Lagerstrom, and H.B. Schioth Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives FEBS Lett 554 2003 381 388
-
(2003)
FEBS Lett
, vol.554
, pp. 381-388
-
-
Fredriksson, R.1
Hoglund, P.J.2
Gloriam, D.E.I.3
Lagerstrom, M.C.4
Schioth, H.B.5
-
9
-
-
53549127020
-
Free fatty acid receptors and drug discovery
-
A. Hirasawa, T. Hara, S. Katsuma, T. Adachi, and G. Tsujimoto Free fatty acid receptors and drug discovery Biol Pharm Bull 31 2008 1847 1851
-
(2008)
Biol Pharm Bull
, vol.31
, pp. 1847-1851
-
-
Hirasawa, A.1
Hara, T.2
Katsuma, S.3
Adachi, T.4
Tsujimoto, G.5
-
10
-
-
75749092632
-
New frontiers in gut nutrient sensor research: Free fatty acid sensing in the gastrointestinal tract
-
S. Miyauchi, A. Hirasawa, A. Ichimura, T. Hara, and G. Tsujimoto New frontiers in gut nutrient sensor research: free fatty acid sensing in the gastrointestinal tract J Pharmacol Sci 112 2010 19 24
-
(2010)
J Pharmacol Sci
, vol.112
, pp. 19-24
-
-
Miyauchi, S.1
Hirasawa, A.2
Ichimura, A.3
Hara, T.4
Tsujimoto, G.5
-
11
-
-
80052021813
-
Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases
-
S. Talukdar, J.M. Olefsky, and O. Osborn Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases Trends Pharmacol Sci 32 2011 543 550
-
(2011)
Trends Pharmacol Sci
, vol.32
, pp. 543-550
-
-
Talukdar, S.1
Olefsky, J.M.2
Osborn, O.3
-
13
-
-
13444263540
-
Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120
-
A. Hirasawa, K. Tsumaya, T. Awaji, S. Katsuma, T. Adachi, and M. Yamada Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120 Nat Med 11 2005 90 94
-
(2005)
Nat Med
, vol.11
, pp. 90-94
-
-
Hirasawa, A.1
Tsumaya, K.2
Awaji, T.3
Katsuma, S.4
Adachi, T.5
Yamada, M.6
-
14
-
-
72649095986
-
Cloning, expression, and pharmacological characterization of the GPR120 free fatty acid receptor from cynomolgus monkey: Comparison with human GPR120 splice variants
-
K. Moore, Q. Zhang, N. Murgolo, T. Hosted, and R. Duffy Cloning, expression, and pharmacological characterization of the GPR120 free fatty acid receptor from cynomolgus monkey: comparison with human GPR120 splice variants Comp Biochem Physiol B Biochem Mol Biol 154 2009 419 426
-
(2009)
Comp Biochem Physiol B Biochem Mol Biol
, vol.154
, pp. 419-426
-
-
Moore, K.1
Zhang, Q.2
Murgolo, N.3
Hosted, T.4
Duffy, R.5
-
15
-
-
45849153782
-
Cloning and characterization of the rat free fatty acid receptor GPR120: In vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells
-
T. Tanaka, T. Yano, T. Adachi, T.A. Koshimizu, A. Hirasawa, and G. Tsujimoto Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells Naunyn Schmiedebergs Arch Pharmacol 377 2008 515 522
-
(2008)
Naunyn Schmiedebergs Arch Pharmacol
, vol.377
, pp. 515-522
-
-
Tanaka, T.1
Yano, T.2
Adachi, T.3
Koshimizu, T.A.4
Hirasawa, A.5
Tsujimoto, G.6
-
16
-
-
33646162635
-
GRKs and beta-arrestins: Roles in receptor silencing, trafficking and signaling
-
E. Reiter, and R.J. Lefkowitz GRKs and beta-arrestins: roles in receptor silencing, trafficking and signaling Trends Endocrinol Metab 17 2006 159 165
-
(2006)
Trends Endocrinol Metab
, vol.17
, pp. 159-165
-
-
Reiter, E.1
Lefkowitz, R.J.2
-
17
-
-
47849101639
-
Location, location, location ... site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling
-
A.B. Tobin, A.J. Butcher, and K.C. Kong Location, location, location... site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling Trends Pharmacol Sci 29 2008 413 420
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 413-420
-
-
Tobin, A.B.1
Butcher, A.J.2
Kong, K.C.3
-
18
-
-
52649145895
-
GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy
-
Y. Xue, J. Ren, X.J. Gao, C.J. Jin, L.P. Wen, and X.B. Yao GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy Mol Cell Proteomics 7 2008 1598 1608
-
(2008)
Mol Cell Proteomics
, vol.7
, pp. 1598-1608
-
-
Xue, Y.1
Ren, J.2
Gao, X.J.3
Jin, C.J.4
Wen, L.P.5
Yao, X.B.6
-
19
-
-
77953287113
-
Agonism with the omega-3 fatty acids alpha-linolenic acid and docosahexaenoic acid mediates phosphorylation of both the short and long isoforms of the human GPR120 receptor
-
R.N. Burns, and N.H. Moniri Agonism with the omega-3 fatty acids alpha-linolenic acid and docosahexaenoic acid mediates phosphorylation of both the short and long isoforms of the human GPR120 receptor Biochem Biophys Res Commun 396 2010 1030 1035
-
(2010)
Biochem Biophys Res Commun
, vol.396
, pp. 1030-1035
-
-
Burns, R.N.1
Moniri, N.H.2
-
20
-
-
60849130394
-
Distribution and regulation of protein expression of the free fatty acid receptor GPR120
-
S. Miyauchi, A. Hirasawa, T. Iga, N. Liu, C. Itsubo, and K. Sadakane Distribution and regulation of protein expression of the free fatty acid receptor GPR120 Naunyn Schmiedebergs Arch Pharmacol 379 2009 427 434
-
(2009)
Naunyn Schmiedebergs Arch Pharmacol
, vol.379
, pp. 427-434
-
-
Miyauchi, S.1
Hirasawa, A.2
Iga, T.3
Liu, N.4
Itsubo, C.5
Sadakane, K.6
-
21
-
-
70350610662
-
Anatomical and histological profiling of orphan G-protein-coupled receptor expression in gastrointestinal tract of C57BL/6J mice
-
J. Ito, M. Ito, H. Nambu, T. Fujikawa, K. Tanaka, and H. Iwaasa Anatomical and histological profiling of orphan G-protein-coupled receptor expression in gastrointestinal tract of C57BL/6J mice Cell Tissue Res 338 2009 257 269
-
(2009)
Cell Tissue Res
, vol.338
, pp. 257-269
-
-
Ito, J.1
Ito, M.2
Nambu, H.3
Fujikawa, T.4
Tanaka, K.5
Iwaasa, H.6
-
22
-
-
33947700521
-
GPR expression in the rat taste bud relating to fatty acid sensing
-
S. Matsumura, T. Mizushige, T. Yoneda, T. Iwanaga, S. Tsuzuki, and K. Inoue GPR expression in the rat taste bud relating to fatty acid sensing Biomed Res 28 2007 49 55
-
(2007)
Biomed Res
, vol.28
, pp. 49-55
-
-
Matsumura, S.1
Mizushige, T.2
Yoneda, T.3
Iwanaga, T.4
Tsuzuki, S.5
Inoue, K.6
-
23
-
-
58149464981
-
Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells
-
H.E. Parker, A.M. Habib, G.J. Rogers, F.M. Gribble, and F. Reimann Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells Diabetologia 52 2009 289 298
-
(2009)
Diabetologia
, vol.52
, pp. 289-298
-
-
Parker, H.E.1
Habib, A.M.2
Rogers, G.J.3
Gribble, F.M.4
Reimann, F.5
-
24
-
-
84863084353
-
Sensing of fatty acids for octanoylation of ghrelin involves a gustatory g-protein
-
S. Janssen, J. Laermans, H. Iwakura, J. Tack, and I. Depoortere Sensing of fatty acids for octanoylation of ghrelin involves a gustatory g-protein PLoS One 7 2012 e40168
-
(2012)
PLoS One
, vol.7
, pp. 40168
-
-
Janssen, S.1
Laermans, J.2
Iwakura, H.3
Tack, J.4
Depoortere, I.5
-
25
-
-
77954501905
-
Establishment of a novel ghrelin-producing cell line
-
H. Iwakura, Y. Li, H. Ariyasu, H. Hosoda, N. Kanamoto, and M. Bando Establishment of a novel ghrelin-producing cell line Endocrinology 151 2010 2940 2945
-
(2010)
Endocrinology
, vol.151
, pp. 2940-2945
-
-
Iwakura, H.1
Li, Y.2
Ariyasu, H.3
Hosoda, H.4
Kanamoto, N.5
Bando, M.6
-
26
-
-
33846468320
-
The regulation of adipogenesis through GPR120
-
C. Gotoh, Y.H. Hong, T. Iga, D. Hishikawa, Y. Suzuki, and S.H. Song The regulation of adipogenesis through GPR120 Biochem Biophys Res Commun 354 2007 591 597
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 591-597
-
-
Gotoh, C.1
Hong, Y.H.2
Iga, T.3
Hishikawa, D.4
Suzuki, Y.5
Song, S.H.6
-
27
-
-
77956165390
-
GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects
-
D.Y. Oh, S. Talukdar, E.J. Bae, T. Imamura, H. Morinaga, and W.Q. Fan GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects Cell 142 2010 687 698
-
(2010)
Cell
, vol.142
, pp. 687-698
-
-
Oh, D.Y.1
Talukdar, S.2
Bae, E.J.3
Imamura, T.4
Morinaga, H.5
Fan, W.Q.6
-
28
-
-
84855900663
-
G protein-coupled receptors in human fat taste perception
-
M.M. Galindo, N. Voigt, J. Stein, J. van Lengerich, J.D. Raguse, and T. Hofmann G protein-coupled receptors in human fat taste perception Chem Senses 37 2012 123 139
-
(2012)
Chem Senses
, vol.37
, pp. 123-139
-
-
Galindo, M.M.1
Voigt, N.2
Stein, J.3
Van Lengerich, J.4
Raguse, J.D.5
Hofmann, T.6
-
29
-
-
70349988797
-
G-protein coupled receptors mediating long chain fatty acid signalling in the pancreatic beta-cell
-
N.G. Morgan, and S. Dhayal G-protein coupled receptors mediating long chain fatty acid signalling in the pancreatic beta-cell Biochem Pharmacol 78 2009 1419 1427
-
(2009)
Biochem Pharmacol
, vol.78
, pp. 1419-1427
-
-
Morgan, N.G.1
Dhayal, S.2
-
30
-
-
80555157690
-
Processing of proglucagon to GLP-1 in pancreatic alpha-cells: Is this a paracrine mechanism enabling GLP-1 to act on beta-cells?
-
N.M. Whalley, L.E. Pritchard, D.M. Smith, and A. White Processing of proglucagon to GLP-1 in pancreatic alpha-cells: is this a paracrine mechanism enabling GLP-1 to act on beta-cells? J Endocrinol 211 2011 99 106
-
(2011)
J Endocrinol
, vol.211
, pp. 99-106
-
-
Whalley, N.M.1
Pritchard, L.E.2
Smith, D.M.3
White, A.4
-
31
-
-
83755225879
-
Diet-induced obesity up-regulates the abundance of GPR43 and GPR120 in a tissue specific manner
-
L.M. Cornall, M.L. Mathai, D.H. Hryciw, and A.J. McAinch Diet-induced obesity up-regulates the abundance of GPR43 and GPR120 in a tissue specific manner Cell Physiol Biochem 28 2011 949 958
-
(2011)
Cell Physiol Biochem
, vol.28
, pp. 949-958
-
-
Cornall, L.M.1
Mathai, M.L.2
Hryciw, D.H.3
McAinch, A.J.4
-
32
-
-
53649083414
-
Oleic acid induces ERK1/2 activation and AP-1 DNA binding activity through a mechanism involving Src kinase and EGFR transactivation in breast cancer cells
-
A. Soto-Guzman, T. Robledo, M. Lopez-Perez, and E.P. Salazar Oleic acid induces ERK1/2 activation and AP-1 DNA binding activity through a mechanism involving Src kinase and EGFR transactivation in breast cancer cells Mol Cell Endocrinol 294 2008 81 91
-
(2008)
Mol Cell Endocrinol
, vol.294
, pp. 81-91
-
-
Soto-Guzman, A.1
Robledo, T.2
Lopez-Perez, M.3
Salazar, E.P.4
-
33
-
-
84872413987
-
The role of cholecystokinin receptors in the short-term control of food intake
-
A.I. Sayegh The role of cholecystokinin receptors in the short-term control of food intake Prog Mol Biol Trans Sci 114 2012 1 40
-
(2012)
Prog Mol Biol Trans Sci
, vol.114
, pp. 1-40
-
-
Sayegh, A.I.1
-
34
-
-
0032899523
-
Fatty acid chain length determines cholecystokinin secretion and effect on human gastric motility
-
J. McLaughlin, M. Grazia Luca, M.N. Jones, M. D'Amato, G.J. Dockray, and D.G. Thompson Fatty acid chain length determines cholecystokinin secretion and effect on human gastric motility Gastroenterology 116 1999 46 53
-
(1999)
Gastroenterology
, vol.116
, pp. 46-53
-
-
McLaughlin, J.1
Grazia Luca, M.2
Jones, M.N.3
D'Amato, M.4
Dockray, G.J.5
Thompson, D.G.6
-
35
-
-
45849102105
-
Free fatty acids induce cholecystokinin secretion through GPR120
-
T. Tanaka, S. Katsuma, T. Adachi, T.A. Koshimizu, A. Hirasawa, and G. Tsujimoto Free fatty acids induce cholecystokinin secretion through GPR120 Naunyn Schmiedebergs Arch Pharmacol 377 2008 523 527
-
(2008)
Naunyn Schmiedebergs Arch Pharmacol
, vol.377
, pp. 523-527
-
-
Tanaka, T.1
Katsuma, S.2
Adachi, T.3
Koshimizu, T.A.4
Hirasawa, A.5
Tsujimoto, G.6
-
36
-
-
83455250388
-
TRPM5 is critical for linoleic acid-induced CCK secretion from the enteroendocrine cell line, STC-1
-
B.P. Shah, P. Liu, T. Yu, D.R. Hansen, and T.A. Gilbertson TRPM5 is critical for linoleic acid-induced CCK secretion from the enteroendocrine cell line, STC-1 Am J Physiol Cell Physiol 302 2012 C210 C219
-
(2012)
Am J Physiol Cell Physiol
, vol.302
-
-
Shah, B.P.1
Liu, P.2
Yu, T.3
Hansen, D.R.4
Gilbertson, T.A.5
-
37
-
-
68349086914
-
Novel selective ligands for free fatty acid receptors GPR120 and GPR40
-
T. Hara, A. Hirasawa, Q. Sun, K. Sadakane, C. Itsubo, and T. Iga Novel selective ligands for free fatty acid receptors GPR120 and GPR40 Naunyn Schmiedebergs Arch Pharmacol 380 2009 247 255
-
(2009)
Naunyn Schmiedebergs Arch Pharmacol
, vol.380
, pp. 247-255
-
-
Hara, T.1
Hirasawa, A.2
Sun, Q.3
Sadakane, K.4
Itsubo, C.5
Iga, T.6
-
38
-
-
84863112820
-
Increased oral detection, but decreased intestinal signaling for fats in mice lacking gut microbiota
-
F.A. Duca, T.D. Swartz, Y. Sakar, and M. Covasa Increased oral detection, but decreased intestinal signaling for fats in mice lacking gut microbiota PLoS One 7 2012 e39748
-
(2012)
PLoS One
, vol.7
, pp. 39748
-
-
Duca, F.A.1
Swartz, T.D.2
Sakar, Y.3
Covasa, M.4
-
39
-
-
34047177401
-
GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo
-
M.G. Latour, T. Alquier, E. Oseid, C. Tremblay, T.L. Jetton, and J. Luo GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo Diabetes 56 2007 1087 1094
-
(2007)
Diabetes
, vol.56
, pp. 1087-1094
-
-
Latour, M.G.1
Alquier, T.2
Oseid, E.3
Tremblay, C.4
Jetton, T.L.5
Luo, J.6
-
40
-
-
0037434991
-
Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40
-
Y. Itoh, Y. Kawamata, M. Harada, M. Kobayashi, R. Fujii, and S. Fukusumi Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40 Nature 422 2003 173 176
-
(2003)
Nature
, vol.422
, pp. 173-176
-
-
Itoh, Y.1
Kawamata, Y.2
Harada, M.3
Kobayashi, M.4
Fujii, R.5
Fukusumi, S.6
-
41
-
-
84858285593
-
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
-
A. Ichimura, A. Hirasawa, O. Poulain-Godefroy, A. Bonnefond, T. Hara, and L. Yengo Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human Nature 483 2012 350 354
-
(2012)
Nature
, vol.483
, pp. 350-354
-
-
Ichimura, A.1
Hirasawa, A.2
Poulain-Godefroy, O.3
Bonnefond, A.4
Hara, T.5
Yengo, L.6
-
42
-
-
84863516095
-
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets
-
J. Taneera, S. Lang, A. Sharma, J. Fadista, Y. Zhou, and E. Ahlqvist A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets Cell Metab 16 2012 122 134
-
(2012)
Cell Metab
, vol.16
, pp. 122-134
-
-
Taneera, J.1
Lang, S.2
Sharma, A.3
Fadista, J.4
Zhou, Y.5
Ahlqvist, E.6
-
43
-
-
0030927581
-
Fat perception is related to PROP taster status
-
B.J. Tepper, and R.J. Nurse Fat perception is related to PROP taster status Physiol Behav 61 1997 949 954
-
(1997)
Physiol Behav
, vol.61
, pp. 949-954
-
-
Tepper, B.J.1
Nurse, R.J.2
-
44
-
-
0027731470
-
Role of olfaction in starch and oil preference
-
I. Ramirez Role of olfaction in starch and oil preference Am J Physiol 265 1993 R1404 R1409
-
(1993)
Am J Physiol
, vol.265
-
-
Ramirez, I.1
-
45
-
-
0029805363
-
The controls of fat intake
-
D. Greenberg, and G.P. Smith The controls of fat intake Psychosom Med 58 1996 559 569
-
(1996)
Psychosom Med
, vol.58
, pp. 559-569
-
-
Greenberg, D.1
Smith, G.P.2
-
46
-
-
0038356470
-
Role of gustation in the recognition of oleate and triolein in anosmic rats
-
T. Fukuwatari, K. Shibata, K. Iguchi, T. Saeki, A. Iwata, and K. Tani Role of gustation in the recognition of oleate and triolein in anosmic rats Physiol Behav 78 2003 579 583
-
(2003)
Physiol Behav
, vol.78
, pp. 579-583
-
-
Fukuwatari, T.1
Shibata, K.2
Iguchi, K.3
Saeki, T.4
Iwata, A.5
Tani, K.6
-
47
-
-
0041881949
-
Effects of oral stimulation with fats on the cephalic phase of pancreatic enzyme secretion in esophagostomized rats
-
T. Hiraoka, T. Fukuwatari, M. Imaizumi, and T. Fushiki Effects of oral stimulation with fats on the cephalic phase of pancreatic enzyme secretion in esophagostomized rats Physiol Behav 79 2003 713 717
-
(2003)
Physiol Behav
, vol.79
, pp. 713-717
-
-
Hiraoka, T.1
Fukuwatari, T.2
Imaizumi, M.3
Fushiki, T.4
-
48
-
-
27644533906
-
CD36 involvement in orosensory detection of dietary lipids, spontaneous fat preference, and digestive secretions
-
F. Laugerette, P. Passilly-Degrace, B. Patris, I. Niot, M. Febbraio, and J.P. Montmayeur CD36 involvement in orosensory detection of dietary lipids, spontaneous fat preference, and digestive secretions J Clin Invest 115 2005 3177 3184
-
(2005)
J Clin Invest
, vol.115
, pp. 3177-3184
-
-
Laugerette, F.1
Passilly-Degrace, P.2
Patris, B.3
Niot, I.4
Febbraio, M.5
Montmayeur, J.P.6
-
50
-
-
28444441946
-
Fatty acid responses in taste cells from obesity-prone and -resistant rats
-
T.A. Gilbertson, L. Liu, I. Kim, C.A. Burks, and D.R. Hansen Fatty acid responses in taste cells from obesity-prone and -resistant rats Physiol Behav 86 2005 681 690
-
(2005)
Physiol Behav
, vol.86
, pp. 681-690
-
-
Gilbertson, T.A.1
Liu, L.2
Kim, I.3
Burks, C.A.4
Hansen, D.R.5
-
51
-
-
0031559890
-
Expression of the putative membrane fatty acid transporter (FAT) in taste buds of the circumvallate papillae in rats
-
T. Fukuwatari, T. Kawada, M. Tsuruta, T. Hiraoka, T. Iwanaga, and E. Sugimoto Expression of the putative membrane fatty acid transporter (FAT) in taste buds of the circumvallate papillae in rats FEBS Lett 414 1997 461 464
-
(1997)
FEBS Lett
, vol.414
, pp. 461-464
-
-
Fukuwatari, T.1
Kawada, T.2
Tsuruta, M.3
Hiraoka, T.4
Iwanaga, T.5
Sugimoto, E.6
-
52
-
-
0033582645
-
Putative mammalian taste receptors: A class of taste-specific GPCRs with distinct topographic selectivity
-
M.A. Hoon, E. Adler, J. Lindemeier, J.F. Battey, N.J. Ryba, and C.S. Zuker Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity Cell 96 1999 541 551
-
(1999)
Cell
, vol.96
, pp. 541-551
-
-
Hoon, M.A.1
Adler, E.2
Lindemeier, J.3
Battey, J.F.4
Ryba, N.J.5
Zuker, C.S.6
-
53
-
-
0035839040
-
Mammalian sweet taste receptors
-
G. Nelson, M.A. Hoon, J. Chandrashekar, Y. Zhang, N.J. Ryba, and C.S. Zuker Mammalian sweet taste receptors Cell 106 2001 381 390
-
(2001)
Cell
, vol.106
, pp. 381-390
-
-
Nelson, G.1
Hoon, M.A.2
Chandrashekar, J.3
Zhang, Y.4
Ryba, N.J.5
Zuker, C.S.6
-
54
-
-
0037075555
-
An amino-acid taste receptor
-
G. Nelson, J. Chandrashekar, M.A. Hoon, L. Feng, G. Zhao, and N.J. Ryba An amino-acid taste receptor Nature 416 2002 199 202
-
(2002)
Nature
, vol.416
, pp. 199-202
-
-
Nelson, G.1
Chandrashekar, J.2
Hoon, M.A.3
Feng, L.4
Zhao, G.5
Ryba, N.J.6
-
55
-
-
77954134133
-
Taste preference for fatty acids is mediated by GPR40 and GPR120
-
C. Cartoni, K. Yasumatsu, T. Ohkuri, N. Shigemura, R. Yoshida, and N. Godinot Taste preference for fatty acids is mediated by GPR40 and GPR120 J Neurosci 30 2010 8376 8382
-
(2010)
J Neurosci
, vol.30
, pp. 8376-8382
-
-
Cartoni, C.1
Yasumatsu, K.2
Ohkuri, T.3
Shigemura, N.4
Yoshida, R.5
Godinot, N.6
-
56
-
-
0023624892
-
Obesity and postmenopausal bone loss - The influence of obesity on vertebral density and bone turnover in postmenopausal women
-
C. Ribot, F. Tremollieres, J.M. Pouilles, M. Bonneu, F. Germain, and J.P. Louvet Obesity and postmenopausal bone loss - the influence of obesity on vertebral density and bone turnover in postmenopausal women Bone 8 1987 327 331
-
(1987)
Bone
, vol.8
, pp. 327-331
-
-
Ribot, C.1
Tremollieres, F.2
Pouilles, J.M.3
Bonneu, M.4
Germain, F.5
Louvet, J.P.6
-
57
-
-
0026775342
-
Fat mass is an important determinant of whole-body bone-density in premenopausal women but not in men
-
I.R. Reid, L.D. Plank, and M.C. Evans Fat mass is an important determinant of whole-body bone-density in premenopausal women but not in men J Clin Endocrinol Metab 75 1992 779 782
-
(1992)
J Clin Endocrinol Metab
, vol.75
, pp. 779-782
-
-
Reid, I.R.1
Plank, L.D.2
Evans, M.C.3
-
58
-
-
0026642505
-
Determinants of total-body and regional bone-mineral density in normal postmenopausal women - A key role for fat mass
-
I.R. Reid, R. Ames, M.C. Evans, S. Sharpe, G. Gamble, and J.T. France Determinants of total-body and regional bone-mineral density in normal postmenopausal women - a key role for fat mass J Clin Endocrinol Metab 75 1992 45 51
-
(1992)
J Clin Endocrinol Metab
, vol.75
, pp. 45-51
-
-
Reid, I.R.1
Ames, R.2
Evans, M.C.3
Sharpe, S.4
Gamble, G.5
France, J.T.6
-
59
-
-
0036861322
-
Relationships among body mass, its components, and bone
-
I.R. Reid Relationships among body mass, its components, and bone Bone 31 2002 547 555
-
(2002)
Bone
, vol.31
, pp. 547-555
-
-
Reid, I.R.1
-
60
-
-
54349086815
-
Modulation of osteoclastogenesis by fatty acids
-
J. Cornish, A. MacGibbon, J.M. Lin, M. Watson, K.E. Callon, and P.C. Tong Modulation of osteoclastogenesis by fatty acids Endocrinology 149 2008 5688 5695
-
(2008)
Endocrinology
, vol.149
, pp. 5688-5695
-
-
Cornish, J.1
MacGibbon, A.2
Lin, J.M.3
Watson, M.4
Callon, K.E.5
Tong, P.C.6
-
62
-
-
33845866857
-
Inflammation and metabolic disorders
-
G.S. Hotamisligil Inflammation and metabolic disorders Nature 444 2006 860 867
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
64
-
-
19044393872
-
Adipose tissue, inflammation, and cardiovascular disease
-
A.H. Berg, and P.E. Scherer Adipose tissue, inflammation, and cardiovascular disease Circ Res 96 2005 939 949
-
(2005)
Circ Res
, vol.96
, pp. 939-949
-
-
Berg, A.H.1
Scherer, P.E.2
-
65
-
-
68749109536
-
A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth
-
B.Z. Qian, Y. Deng, J.H. Im, R.J. Muschel, Y.Y. Zou, and J.F. Li A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth PLoS One 4 2009 e6562
-
(2009)
PLoS One
, vol.4
, pp. 6562
-
-
Qian, B.Z.1
Deng, Y.2
Im, J.H.3
Muschel, R.J.4
Zou, Y.Y.5
Li, J.F.6
-
67
-
-
77958593218
-
N-3 fatty acids and periodontitis in US adults
-
A.Z. Naqvi, C. Buettner, R.S. Phillips, R.B. Davis, and K.J. Mukamal n-3 fatty acids and periodontitis in US adults J Am Diet Assoc 110 2010 1669 1675
-
(2010)
J Am Diet Assoc
, vol.110
, pp. 1669-1675
-
-
Naqvi, A.Z.1
Buettner, C.2
Phillips, R.S.3
Davis, R.B.4
Mukamal, K.J.5
-
68
-
-
61849109389
-
Omega-3 fatty acid supplementation decreases matrix metalloproteinase-9 production in relapsing-remitting multiple sclerosis
-
L. Shinto, G. Marracci, S. Baldauf-Wagner, A. Strehlow, V. Yadav, and L. Stuber Omega-3 fatty acid supplementation decreases matrix metalloproteinase-9 production in relapsing-remitting multiple sclerosis Prostaglandins Leukot Essent Fatty Acids 80 2009 131 136
-
(2009)
Prostaglandins Leukot Essent Fatty Acids
, vol.80
, pp. 131-136
-
-
Shinto, L.1
Marracci, G.2
Baldauf-Wagner, S.3
Strehlow, A.4
Yadav, V.5
Stuber, L.6
-
69
-
-
70349237729
-
Therapeutic potential of n-3 polyunsaturated fatty acids in disease
-
J.W. Fetterman, and M.M. Zdanowicz Therapeutic potential of n-3 polyunsaturated fatty acids in disease Am J Health Syst Pharm 66 2009 1169 1179
-
(2009)
Am J Health Syst Pharm
, vol.66
, pp. 1169-1179
-
-
Fetterman, J.W.1
Zdanowicz, M.M.2
-
70
-
-
84860575447
-
Omega-3 fatty acids in anti-inflammation (pro-resolution) and GPCRs
-
D.S. Im Omega-3 fatty acids in anti-inflammation (pro-resolution) and GPCRs Prog Lipid Res 51 2012 232 237
-
(2012)
Prog Lipid Res
, vol.51
, pp. 232-237
-
-
Im, D.S.1
-
71
-
-
84872419808
-
Low affinity GPCRs for metabolic intermediates: Challenges for pharmacologists
-
N.J. Smith Low affinity GPCRs for metabolic intermediates: challenges for pharmacologists Front Endocrinol (Lausanne) 3 2012 1
-
(2012)
Front Endocrinol (Lausanne)
, vol.3
, pp. 1
-
-
Smith, N.J.1
-
72
-
-
84855971481
-
Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity
-
D.E. Cintra, E.R. Ropelle, J.C. Moraes, J.R. Pauli, J. Morari, and C.T. de Souza Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity PLoS One 7 2012 e30571
-
(2012)
PLoS One
, vol.7
, pp. 30571
-
-
Cintra, D.E.1
Ropelle, E.R.2
Moraes, J.C.3
Pauli, J.R.4
Morari, J.5
De Souza, C.T.6
-
73
-
-
0026551309
-
Fatty-acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor
-
M. Gottlicher, E. Widmark, Q. Li, and J.A. Gustafsson Fatty-acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor Proc Natl Acad Sci USA 89 1992 4653 4657
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 4653-4657
-
-
Gottlicher, M.1
Widmark, E.2
Li, Q.3
Gustafsson, J.A.4
-
75
-
-
33745607930
-
Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: Identification of agonist and antagonist small molecules
-
C.P. Briscoe, A.J. Peat, S.C. McKeown, D.F. Corbett, A.S. Goetz, and T.R. Littleton Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules Br J Pharmacol 148 2006 619 628
-
(2006)
Br J Pharmacol
, vol.148
, pp. 619-628
-
-
Briscoe, C.P.1
Peat, A.J.2
McKeown, S.C.3
Corbett, D.F.4
Goetz, A.S.5
Littleton, T.R.6
-
76
-
-
57349135245
-
Identification of G protein-coupled receptor 120-selective agonists derived from PPAR gamma agonists
-
T. Suzuki, S.I. Igari, A. Hirasawa, M. Hata, M. Ishiguro, and H. Fujieda Identification of G protein-coupled receptor 120-selective agonists derived from PPAR gamma agonists J Med Chem 51 2008 7640 7644
-
(2008)
J Med Chem
, vol.51
, pp. 7640-7644
-
-
Suzuki, T.1
Igari, S.I.2
Hirasawa, A.3
Hata, M.4
Ishiguro, M.5
Fujieda, H.6
-
77
-
-
84861066914
-
Discovery of a potent and selective GPR120 agonist
-
B. Shimpukade, B.D. Hudson, C.K. Hovgaard, G. Milligan, and T. Ulven Discovery of a potent and selective GPR120 agonist J Med Chem 55 2012 4511 4515
-
(2012)
J Med Chem
, vol.55
, pp. 4511-4515
-
-
Shimpukade, B.1
Hudson, B.D.2
Hovgaard, C.K.3
Milligan, G.4
Ulven, T.5
-
78
-
-
77958142515
-
Structure-activity relationships of GPR120 agonists based on a docking simulation
-
Q. Sun, A. Hirasawa, T. Hara, I. Kimura, T. Adachi, and T. Awaji Structure-activity relationships of GPR120 agonists based on a docking simulation Mol Pharmacol 78 2010 804 810
-
(2010)
Mol Pharmacol
, vol.78
, pp. 804-810
-
-
Sun, Q.1
Hirasawa, A.2
Hara, T.3
Kimura, I.4
Adachi, T.5
Awaji, T.6
-
79
-
-
84859949278
-
Differential signaling by splice variants of the human free fatty acid receptor GPR120
-
S.J. Watson, A.J.H. Brown, and N.D. Holliday Differential signaling by splice variants of the human free fatty acid receptor GPR120 Mol Pharmacol 81 2012 631 642
-
(2012)
Mol Pharmacol
, vol.81
, pp. 631-642
-
-
Watson, S.J.1
Brown, A.J.H.2
Holliday, N.D.3
-
80
-
-
84872407744
-
Drug discovery opportunities and challenges at G protein-coupled receptors for long chain free fatty acids
-
N.D. Holliday, S.J. Watson, and A.J. Brown Drug discovery opportunities and challenges at G protein-coupled receptors for long chain free fatty acids Front Endocrinol (Lausanne) 2 2011 112
-
(2011)
Front Endocrinol (Lausanne)
, vol.2
, pp. 112
-
-
Holliday, N.D.1
Watson, S.J.2
Brown, A.J.3
-
81
-
-
4043093705
-
Functional characterization of melanocortin-3 receptor variants identify a loss-of-function mutation involving an amino acid critical for G protein-coupled receptor activation
-
Y.X. Tao, and D.L. Segaloff Functional characterization of melanocortin-3 receptor variants identify a loss-of-function mutation involving an amino acid critical for G protein-coupled receptor activation J Clin Endocrinol Metab 89 2004 3936 3942
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 3936-3942
-
-
Tao, Y.X.1
Segaloff, D.L.2
-
82
-
-
33746527488
-
Inactivating mutations of G protein-coupled receptors and diseases: Structure-function insights and therapeutic implications
-
Y.X. Tao Inactivating mutations of G protein-coupled receptors and diseases: structure-function insights and therapeutic implications Pharmacol Ther 111 2006 949 973
-
(2006)
Pharmacol Ther
, vol.111
, pp. 949-973
-
-
Tao, Y.X.1
-
83
-
-
21244503501
-
Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1
-
S. Katsuma, N. Hatae, T. Yano, Y. Ruike, M. Kimura, and A. Hirasawa Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1 J Biol Chem 280 2005 19507 19515
-
(2005)
J Biol Chem
, vol.280
, pp. 19507-19515
-
-
Katsuma, S.1
Hatae, N.2
Yano, T.3
Ruike, Y.4
Kimura, M.5
Hirasawa, A.6
-
84
-
-
33847037154
-
Protein kinase C zeta is required for oleic acid-induced secretion of glucagon-like peptide-1 by intestinal endocrine L cells
-
R. Iakoubov, A. Izzo, A. Yeung, C.I. Whiteside, and P.L. Brubaker Protein kinase C zeta is required for oleic acid-induced secretion of glucagon-like peptide-1 by intestinal endocrine L cells Endocrinology 148 2007 1089 1098
-
(2007)
Endocrinology
, vol.148
, pp. 1089-1098
-
-
Iakoubov, R.1
Izzo, A.2
Yeung, A.3
Whiteside, C.I.4
Brubaker, P.L.5
-
85
-
-
84872369928
-
Altered expression of gustatory-signaling elements in gastric tissue of morbidly obese patients
-
P. Widmayer, M. Kuper, M. Kramer, A. Konigsrainer, and H. Breer Altered expression of gustatory-signaling elements in gastric tissue of morbidly obese patients Int J Obes (Lond) 36 2012 1353 1359 http://dx.doi.org/10.1038/ijo.2011. 216
-
(2012)
Int J Obes (Lond)
, vol.36
, pp. 1353-1359
-
-
Widmayer, P.1
Kuper, M.2
Kramer, M.3
Konigsrainer, A.4
Breer, H.5
-
86
-
-
34447633368
-
Conformational complexity of G-protein-coupled receptors
-
B.K. Kobilka, and X. Deupi Conformational complexity of G-protein-coupled receptors Trends Pharmacol Sci 28 2007 397 406
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 397-406
-
-
Kobilka, B.K.1
Deupi, X.2
-
88
-
-
34548758543
-
Splicing in disease: Disruption of the splicing code and the decoding machinery
-
G.S. Wang, and T.A. Cooper Splicing in disease: disruption of the splicing code and the decoding machinery Nat Rev Genet 8 2007 749 761
-
(2007)
Nat Rev Genet
, vol.8
, pp. 749-761
-
-
Wang, G.S.1
Cooper, T.A.2
-
89
-
-
33749017409
-
The human obesity gene map: The 2005 update
-
T. Rankinen, A. Zuberi, Y.C. Chagnon, S.J. Weisnagel, G. Argyropoulos, and B. Walts The human obesity gene map: the 2005 update Obesity 14 2006 529 644
-
(2006)
Obesity
, vol.14
, pp. 529-644
-
-
Rankinen, T.1
Zuberi, A.2
Chagnon, Y.C.3
Weisnagel, S.J.4
Argyropoulos, G.5
Walts, B.6
|