TRPM5 is critical for linoleic acid-induced CCK secretion from the enteroendocrine cell line, STC-1

American Journal of Physiology - Cell Physiology

Volumn 302, Issue 1, 2012, Pages

  Shah, Bhavik P ^a   Liu, Pin ^a   Yu, Tian ^a   Hansen, Dane R ^a   Gilbertson, Timothy A ^a  

^a UTAH STATE UNIVERSITY   (United States)

Author keywords

Calcium; Cholecystokinin; GPR120; Patch clamp recording

Indexed keywords

CALCIUM; CHOLECYSTOKININ; FATTY ACID; G PROTEIN COUPLED RECEPTOR 120; LINOLEIC ACID; MESSENGER RNA; MONOVALENT CATION; PHOSPHOLIPASE C; PROTEIN G; SODIUM; TRANSIENT RECEPTOR POTENTIAL CHANNEL M5;

ANIMAL CELL; ARTICLE; BITTER TASTE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; ENTEROENDOCRINE CELL; EXTRACELLULAR SPACE; HORMONE RELEASE; MEMBRANE ELECTROPHYSIOLOGY; MOUSE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOMETRY; REAL TIME ECHOGRAPHY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SODIUM TRANSPORT; SWEETNESS; TASTE DISCRIMINATION;

ANIMALS; CALCIUM; CELL LINE, TUMOR; CELL POLARITY; CHOLECYSTOKININ; DOWN-REGULATION; ENTEROENDOCRINE CELLS; LINOLEIC ACID; MEMBRANE POTENTIALS; MICE; MICE, TRANSGENIC; RNA INTERFERENCE; TRPM CATION CHANNELS; UP-REGULATION;

EID: 83455250388     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00209.2011     Document Type: Article

References (30)

1. Bezencon C, le Coutre J, Damak S. Taste-signaling proteins are coexpressed in solitary intestinal epithelial cells. Chem Senses 32: 41-49, 2007.
2. Briscoe CP, Tadayyon M, Andrews JL, Benson WG, Chambers JK, Eilert MM, Ellis C, Elshourbagy NA, Goetz AS, Minnick DT, Murdock PR, Sauls HR Jr, Shabon U, Spinage LD, Strum JC, Szekeres PG, Tan KB, Way JM, Ignar DM, Wilson S, Muir AI. The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. J Biol Chem 278: 11303-11311, 2003.
3. Brown AJ, Goldsworthy SM, Barnes AA, Eilert MM, Tcheang L, Daniels D, Muir AI, Wigglesworth MJ, Kinghorn I, Fraser NJ, Pike NB, Strum JC, Steplewski KM, Murdock PR, Holder JC, Marshall FH, Szekeres PG, Wilson S, Ignar DM, Foord SM, Wise A, Dowell SJ. The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem 278: 11312-11319, 2003.
4. + channels. Am J Physiol Cell Physiol 291: C726-C739, 2006.
5. + channels in taste receptor cells: gustatory cues for dietary fat. Am J Physiol Cell Physiol 272: C1203-C1210, 1997.
6. Gutzwiller JP, Goke B, Drewe J, Hildebrand P, Ketterer S, Handschin D, Winterhalder R, Conen D, Beglinger C. Glucagon-like peptide-1: a potent regulator of food intake in humans. Gut 44: 81-86, 1999.
7. Herrmann C, Goke R, Richter G, Fehmann HC, Arnold R, Goke B. Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients. Digestion 56: 117-126, 1995.
8. Hirasawa A, Hara T, Katsuma S, Adachi T, Tsujimoto G. Free fatty acid receptors and drug discovery. Biol Pharm Bull 31: 1847-1851, 2008.
9. Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T, Yamada M, Sugimoto Y, Miyazaki S, Tsujimoto G. Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nat Med 11: 90-94, 2005.
10. Itoh Y, Kawamata Y, Harada M, Kobayashi M, Fujii R, Fukusumi S, Ogi K, Hosoya M, Tanaka Y, Uejima H, Tanaka H, Maruyama M, Satoh R, Okubo S, Kizawa H, Komatsu H, Matsumura F, Noguchi Y, Shinohara T, Hinuma S, Fujisawa Y, Fujino M. Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. Nature 422: 173-176, 2003.
11. Kaske S, Krasteva G, Konig P, Kummer W, Hofmann T, Gudermann T, Chubanov V. TRPM5, a taste-signaling transient receptor potential ion-channel, is a ubiquitous signaling component in chemosensory cells. BMC Neurosci 8: 49, 2007.
12. Laugerette F, Passilly-Degrace P, Patris B, Niot I, Febbraio M, Montmayeur JP, Besnard P. CD36 involvement in orosensory detection of dietary lipids, spontaneous fat preference, and digestive secretions. J Clin Invest 115: 3177-3184, 2005.
13. Le Poul E, Loison C, Struyf S, Springael JY, Lannoy V, Decobecq ME, Brezillon S, Dupriez V, Vassart G, Van Damme J, Parmentier M, Detheux M. Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. J Biol Chem 278: 25481-25489, 2003.
14. Liddle RA. Cholecystokinin cells. Annu Rev Physiol 59: 221-242, 1997.
15. Lin W, Ogura T, Margolskee RF, Finger TE, Restrepo D. TRPM5- expressing solitary chemosensory cells respond to odorous irritants. J Neurophysiol 99: 1451-1460, 2008.
16. + and the phospholipid PIP2 regulate the taste transduction ion channel TRPM5. Proc Natl Acad Sci USA 100: 15160-15165, 2003.
17. Liu P, Shah BP, Croasdell S, Gilbertson TA. Transient receptor potential channel type M5 is essential for fat taste. J Neurosci 31: 8634-8642, 2011.
18. +-dependent mechanism in the enteroendocrine cell line STC-1. J Physiol 513: 11-18, 1998.
19. Palmer RK, Atwal K, Bakaj I, Carlucci-Derbyshire S, Buber MT, Cerne R, Cortes RY, Devantier HR, Jorgensen V, Pawlyk A, Lee SP, Sprous DG, Zhang Z, Bryant R. Triphenylphosphine oxide is a potentand selective inhibitor of the transient receptor potential melastatin-5 ion channel. Assay Drug Dev Technol 8: 703-713, 2010.
20. Perez CA, Huang L, Rong M, Kozak JA, Preuss AK, Zhang H, Max M, Margolskee RF. A transient receptor potential channel expressed in taste receptor cells. Nat Neurosci 5: 1169-1176, 2002.
21. +]i. Proc Natl Acad Sci USA 100: 15166-15171, 2003.
22. Samuel BS, Shaito A, Motoike T, Rey FE, Backhed F, Manchester JK, Hammer RE, Williams SC, Crowley J, Yanagisawa M, Gordon JI. Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41. Proc Natl Acad Sci USA 105: 16767-16772, 2008.
23. Sidhu SS, Thompson DG, Warhurst G, Case RM, Benson RS. Fatty acid-induced cholecystokinin secretion and changes in intracellular Ca2+ in two enteroendocrine cell lines, STC-1 and GLUTag. J Physiol 528: 165-176, 2000.
24. Smith GP, Gibbs J. Cholecystokinin: a putative satiety signal. Pharmacol Biochem Behav 3: 135-138, 1975.
25. Talavera K, Yasumatsu K, Voets T, Droogmans G, Shigemura N, Ninomiya Y, Margolskee RF, Nilius B. Heat activation of TRPM5 underlies thermal sensitivity of sweet taste. Nature 438: 1022-1025, 2005.
26. Tanaka T, Katsuma S, Adachi T, Koshimizu TA, Hirasawa A, Tsujimoto G. Free fatty acids induce cholecystokinin secretion through GPR120. Naunyn Schmiedebergs Arch Pharmacol 377: 523-527, 2008.
27. Wang J, Wu X, Simonavicius N, Tian H, Ling L. Medium-chain fatty acids as ligands for orphan G protein-coupled receptor GPR84. J Biol Chem 281: 34457-34464, 2006.
28. Welch IM, Sepple CP, Read NW. Comparisons of the effects on satiety and eating behaviour of infusion of lipid into the different regions of the small intestine. Gut 29: 306-311, 1988.
29. Xiong Y, Miyamoto N, Shibata K, Valasek MA, Motoike T, Kedzierski RM, Yanagisawa M. Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci USA 101: 1045-1050, 2004.
30. Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. Cell 112: 293-301, 2003.