Recognition of viruses in the cytoplasm by RLRs and other helicases-how conformational changes, mitochondrial dynamics and ubiquitination control innate immune responses

International Immunology

Volumn 24, Issue 12, 2012, Pages 739-749

  Seng, Ng Chen ^a   Kato, Hiroki ^a   Fujita, Takashi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Anti viral; Interferon; Pathogen recognition receptors; RNA helicases; RNA viruses

Indexed keywords

LGP2 PROTEIN; MDA5 PROTEIN; PROTEIN; RECEPTOR; RETINOIC ACID INDUCIBLE GENE I LIKE RECEPTOR; RETINOIC ACID INDUCIBLE PROTEIN I; RNA HELICASE; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

CONFORMATIONAL TRANSITION; CYTOPLASM; HUMAN; INNATE IMMUNITY; MITOCHONDRION; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; UBIQUITINATION;

ALLOSTERIC REGULATION; ANIMALS; CYTOPLASM; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; MITOCHONDRIA; PROTEIN CONFORMATION; RECEPTORS, PATTERN RECOGNITION; RNA HELICASES; RNA, VIRAL; UBIQUITINATION; VIRUSES;

EID: 84870359715     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxs099     Document Type: Review

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