DExD/H box RNA helicases: From generic motors to specific dissociation functions

Molecular Cell

Volumn 8, Issue 2, 2001, Pages 251-262

  Tanner, N Kyle ^a   Linder, Patrick ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ENZYME; HELICASE; RNA HELICASE; VIRUS ENZYME;

CELL ORGANELLE; CRYSTALLIZATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; GENE EXPRESSION; NONHUMAN; PROTEIN FAMILY; PROTEIN MOTIF; REVIEW; RIBOSOME; RNA EDITING; RNA SPLICING; RNA TRANSCRIPTION; RNA TRANSLATION;

EID: 0034857262     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(01)00329-X     Document Type: Review

References (81)

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3. Crystal structure of ATPase domain of translation initiation factor eIF4A from Saccharomyces cerevisiae - The prototype of the DEAD box protein family
4. The protein data bank
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6. Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicase
7. Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor
8. E. coli Rep oligomers are required to initiate DNA unwinding in vitro
9. Crystal structure of RNA helicase from genotype 1b hepatitis C virus: A feasible mechanism of unwinding duplex RNA
10. Requirement of the DEAD-box protein Ded1p for messenger RNA translation
11. Dhr1p, a putative DEAH-box RNA helicase is associated with the box C+D snoRNA U3
12. Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomes
13. The p20 and Ded1 proteins have antagonistic roles in eIF4E-dependent translation in Saccharomyces cerevisiae
14. Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families
15. Evolution of the SNF2 family of proteins: Subfamilies with distinct sequences and functions
16. ATP-binding site of adenylate kinase: Mechanistic implications of its homology with ras-encoded p21, F1-ATPase, and other nucleotide-binding proteins
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20. Helicases: Amino acid sequence comparisons and structure-function relationships
21. A fission yeast general translation factor reveals links between protein synthesis and cell cycle controls
22. The QRxGRxGRxxxG motif of the vaccinia virus DExH box RNA helicase NPH-II is required for ATP hydrolysis and RNA unwinding but not for RNA binding
23. SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
24. Helicase motifs: The engine that powers DNA unwinding
25. Generation of superhelical torsion by ATP-dependent chromatin remodeling activities
26. RNA helicase activity associated with the human p68 protein
27. The DExH/D protein family database
28. The DExH protein NPH-II is a processive and directional molecular motor for unwinding RNA
29. Active disruption of an RNA-protein interaction by a DExH/D RNA helicase
30. Crystallographic structure of the amino terminal domain of yeast initiation factor 4A, a representative DEAD-box RNA helicase
31. Virus-encoded RNA helicases
32. Mutations that affect dimer formation and helicase activity of the hepatitis C virus helicase
33. The first ATPase domain of the yeast 246-kDa protein is required for in vivo unwinding of the U4/U6 duplex
34. Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: The crystal structure provides insights into the mode of unwinding
35. Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for Sub2, an essential spliceosomal ATPase
36. Major domain swiveling revealed by the crystal structures of complexes of E. coli Rep helicase bound to single-stranded DNA and ADP
37. Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases
38. Protein trans-acting factors involved in ribosome biogenesis in Saccharomyces cerevisiae
39. The NTPase/helicase activities of Drosophila maleless, an essential factor in dosage compensation
40. The rRNA-processing function of the yeast U14 small nucleolar RNA can be rescued by a conserved RNA helicase-like protein
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43. A comprehensive web resource on RNA helicases from the baker's yeast Saccharomyces cerevisiae
44. From RNA helicases to RNPases
45. Mechanisms of helicase-catalyzed DNA unwinding
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47. Crawling and wiggling on DNA: Structural insights to the mechanism of DNA unwinding by helicases
48. ATP-dependent chromatin remodelling: SWI/SNF and Co. are on the job
49. Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex
50. Structure and function of hexameric helicases
51. Mutational analysis of a DEAD box RNA helicase: The mammalian translation initiation factor eIF-4A
52. Helicases and RNA unwinding in translation
53. The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis
54. Interaction of the Escherichia coli DEAD box protein DbpA with 23 S ribosomal RNA
55. The ins and outs of a molecular chaperone machine
56. Further characterization of the helicase activity of eIF4A. Substrate specificity
57. Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F
58. Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p
59. Functional domains of the yeast splicing factor prp22p
60. A new twist on RNA helicases: DExH/D box proteins as RNPases
61. RNA helicase dynamics in pre-mRNA splicing
62. Active site comparisons highlight structural similarities between myosin and other P-loop proteins
63. DNA helicases: "inching forward."
64. Unwinding the "Gordian knot" of helicase action
65. Uncoupling DNA translocation and helicase activity in PcrA: Direct evidence for an active mechanism
66. Mechanical devices of the spliceosome: Motors, clocks, springs, and things
67. Crystal structure of a DEAD box protein from the hyperthermophile Methanococcus jannaschii
68. The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5′ secondary structure
69. Ribozymes: The characteristics and properties of catalytic RNAs
70. + RNA export
71. The Escherichia coli DEAD protein DbpA recognizes a small RNA hairpin in 23S rRNA
72. Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism
73. Ribosome biosynthesis in Saccharomyces cerevisiae
74. Rok1p is a putative RNA helicase required for rRNA processing
75. Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
76. PRP16, a DEAH-box RNA helicase, is recruited to the spliceosome primarily via its nonconserved N-terminal domain
77. Characterization and mutational analysis of the helicase and NTPase activities of hepatitis C virus full-length NS3 protein
78. Alive with DEAD proteins
79. Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein
80. DNA helicases: One small step for PcrA, one giant leap for RecBC?
81. Structure of the hepatitis C virus RNA helicase domain