Structure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity response

Journal of Biological Chemistry

Volumn 283, Issue 23, 2008, Pages 15825-15833

  Murali, Ayaluru ^a   Li, Xiaojun ^a   Ranjith Kumar, C T ^a   Bhardwaj, Kanchan ^a   Holzenburg, Andreas ^a,b   Li, Pingwei ^a   Kao, C Cheng ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b Texas AandM University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMAGE PROCESSING; IMAGE RECONSTRUCTION; NUCLEIC ACIDS; ORGANIC ACIDS;

CASPASE RECRUITMENT DOMAINS; COEXPRESSED; COOPERATIVITY; DNA HELICASE; DO-MAINS; HELICASE; INNATE IMMUNITIES; INSECT CELLS; RNA LIGANDS; RNA RECOGNITIONS; STRUCTURAL SIMILARITIES; VIRAL INFECTIONS;

RNA;

DOUBLE STRANDED DNA; HELICASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN LGP2; RECOMBINANT PROTEIN; RETINOIC ACID INDUCIBLE PROTEIN I; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; DEAD BOX PROTEIN; DHX58 PROTEIN, HUMAN; DOUBLE STRANDED RNA; IFIH1 PROTEIN, HUMAN; RARRES3 PROTEIN, HUMAN; RETINOIC ACID RECEPTOR; RNA HELICASE;

ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME SYNTHESIS; GENE EXPRESSION; HUMAN; HUMAN CELL; IMAGE RECONSTRUCTION; INNATE IMMUNITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; RNA BINDING; ANIMAL; ARMYWORM; CELL LINE; CHEMISTRY; DIMERIZATION; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION; STRUCTURAL HOMOLOGY; STRUCTURE ACTIVITY RELATION; VIRUS INFECTION;

HEXAPODA;

ANIMALS; CELL LINE; DEAD-BOX RNA HELICASES; DIMERIZATION; DNA HELICASES; GENE EXPRESSION; HUMANS; IMMUNITY, NATURAL; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, RETINOIC ACID; RECOMBINANT PROTEINS; RNA HELICASES; RNA, DOUBLE-STRANDED; SIGNAL TRANSDUCTION; SPODOPTERA; STRUCTURAL HOMOLOGY, PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS DISEASES;

EID: 46949102571     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800542200     Document Type: Article

References (35)

1. Meylan, E., and Tschopp, J. (2006) Mol. Cell 22, 561-569
2. Yoneyama, M., and Fujita, T. (2007) J. Biol. Chem. 282, 15315-15318
3. Tenoever, B. R., and Maniatis, T. (2006) Immunity 24, 510-512
4. Nallagatla, S. R., Hwang, J., Toroney, R., Zheng, X., Cameron, C. E., and Bevilacqua, P. C. (2007) Science 318, 1455-1458
5. Saito, T., and Gale, M., Jr. (2007) Curr. Opin. Immunol. 19, 17-23
6. Eisenacher, K., Steinberg, C., Reindl, W., and Krug, A. (2008) Immunobiology 212, 701-714
7. Underhill, D. M. (2004) Curr. Opin. Immunol. 16, 483-487
8. Gaspari, A. A. (2006) J. Am. Acad. Dermatol. 54, S67-S80
9. Kobayashi, T., Takaesu, G., and Yoshimura, A. (2006) Nat. Immunol. 7, 123-124
10. Komuro, A., and Horvath, C. M. (2006) J. Virol. 80, 12332-12342
11. Yoneyama, M., Kikuchi, M., Matsumoto, K., Imaizumi, T., Miyagishi, M., Taira, K., Foy, E., Loo, Y. M., Gale, M., Akira, S., Yonehara, S., Kato, A., and Fujita, T. (2005) J. Immunol. 175, 2851-2858
12. Lee, M. S., and Kim, Y. J. (2007) Mol. Cells 23, 1-10
13. Pichlmair, A., Schulz, O., Tan, C. P., Naslund, T. I., Liljestrom, P., Weber, F., and Sousa, C. R. E. (2006) Science 314, 997-1001
14. Hornung, V., Ellegast, J., Kim, S., Brzozka, K., Jung, A., Kato, H., Poeck, H., Akira, S., Conzelmann, K. K., Schlee, M., Endres, S., and Hartmann, G. (2006) Science 314, 994-997
15. Cui, S., Eisenacher, K., Kirchhofer, A., Brzozka, K., Lammens, A., Lammens, K., Fujita, T., Conzelmann, K. K., Krug, A., and Hopfner, K. P. (2008) Mol. Cell 29, 169-179
16. Takahasi, K., Yoneyama, M., Nishihori, T., Hirai, R., Kumeta, H., Narita, R., Gale, M., Jr., Inagaki, F., and Fujita, T. (2008) Mol. Cell 29, 428-440
17. Lee, M. S., and Min, Y. J. (2007) Annu. Rev. Biochem. 76, 447-480
18. Johnson, C. L., and Gale, M. (2006) Trends Immunol. 27, 1-4
19. Saito, T., Hirai, R., Loo, Y. M., Owen, D., Johnson, C. L., Sinha, S. C., Akira, S., Fujita, T., and Gale, M. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 582-587
20. Rothenfusser, S., Goutagny, N., DiPerna, G., Gong, M., Monks, B. G., Schoenemeyer, A., Yamamoto, M., Akira, S., and Fitzgerald, K. A. (2005) J. Immunol. 175, 5260-5268
21. Vilasco, M., Larrea, E., Vitour, D., Dabo, S., Breiman, A., Regnault, B., Riezu, J. I., Eid, P., Prieto, J., and Meurs, E. F. (2006) Hepatology 44, 1635-1647
22. Vitour, D., and Meurs, E. F. (2007) Science's STKE 2007, pe20
23. Venkataraman, T., Valdes, M., Elsby, R., Kakuta, S., Caceres, G., Saijo, S., Iwakura, Y., and Barber, G. N. (2007) J. Immunol. 178, 6444-6455
24. Nishino, T., Komori, K., Tsuchiya, D., Ishino, Y., and Morikawa, K. (2005) Structure 13, 143-153
25. Kao, C. C., Yang, X., Kline, A., Wang, Q. M., Barket, D., and Heinz, B. A. (2000) J. Virol. 74, 11121-11128
26. Ludtke, S. J., Baldwin, P. R., and Chiu, W. (1999) J. Struct. Biol. 128, 82-97
27. Sun, J., DuFort, C., Daniel, M. C., Murali, A., Chen, C., Gopinath, K., Stein, B., De, M., Rotello, V. M., Holzenburg, A., Kao, C. C., and Dragnea, B. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 1354-1359
28. Pettersen, E. F., Goddard, T. D., Huang, C. C., Couch, G. S., Greenblatt, D. M., Meng, E. C., and Ferrin, T. E. (2004) J. Comput. Chem. 25, 1605-1612
29. Ranjith-Kumar, C. T., Miller, W., Sun, J., Xiong, J., Santos, J., Yarbrough, I., Lamb, R. J., Mills, J., Duffy, K. E., Hoose, S., Cunningham, M., Holzenburg, A., Mbow, M. L., Sarisky, R. T., and Kao, C. C. (2007) J. Biol. Chem. 282, 17696-17705
30. Rixon, F. J., and Chiu, W. (2003) Adv. Protein Chem. 64, 379-408
31. Zhou, Z. H., and Chiu, W. (2003) Adv. Protein Chem. 64, 93-124
32. Caruthers, J. M., and McKay, D. B. (2002) Curr. Opin. Struct. Biol. 12, 123-133
33. Cordin, O., Banroques, J., Tanner, N. K., and Linder, P. (2006) Gene (Amst.) 367, 17-37
34. Kossen, K., Karginov, F. V., and Uhlenbeck, O. C. (2002) J. Mol. Biol. 324, 625-636
35. Park, H. H., Logette, E., Raunser, S., Cuenin, S., Walz, T., Tschopp, J., and Wu, H. (2007) Cell 128, 533-546