Peroxynitrite transforms nerve growth factor into an apoptotic factor for motor neurons

Free Radical Biology and Medicine

Volumn 41, Issue 11, 2006, Pages 1632-1644

  Pehar, Mariana ^a   Vargas, Marcelo R ^a   Robinson, Kristine M ^b   Cassina, Patricia ^c   England, Patrick ^d   Beckman, Joseph S ^b   Alzari, Pedro M ^d   Barbeito, Luis ^a  

^a INSTITUTO DE INVESTIGACIONES BIOLÓGICAS CLEMENTE ESTABLE   (Uruguay)

^b OREGON STATE UNIVERSITY   (United States)

^c DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

^d INSTITUT PASTEUR   (France)

Author keywords

Apoptosis; Free radicals; Motor neurons; NGF; Nitrotyrosine; p75NTR; Peroxynitrite

Indexed keywords

ANTIBODY; NERVE GROWTH FACTOR; NEUROTROPHIN; NEUROTROPHIN RECEPTOR; NITRIC OXIDE; OLIGOMER; PEROXYNITRITE; TYROSINE; URATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; MOLECULAR WEIGHT; MOTONEURON; NITRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; RAT;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELLS, CULTURED; ELECTROPHORETIC MOBILITY SHIFT ASSAY; MASS SPECTROMETRY; MOTOR NEURONS; NERVE GROWTH FACTOR; OLIGONUCLEOTIDES, ANTISENSE; PEROXYNITROUS ACID; RATS; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; RECEPTOR, NERVE GROWTH FACTOR; TYROSINE;

EID: 33750361150     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2006.08.010     Document Type: Article

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