-
1
-
-
0036795530
-
Activated TCRs remain marked for internalization after dissociation from pMHC
-
doi:10.1038/ni838
-
Coombs, D., Kalergis, A., Nathenson, S., Wofsy, C. &Goldstein, B. 2002 Activated TCRs remain marked for internalization after dissociation from pMHC. Nat. Immunol. 3, 926-931. (doi:10.1038/ni838)
-
(2002)
Nat. Immunol.
, vol.3
, pp. 926-931
-
-
Coombs, D.1
Kalergis, A.2
Nathenson, S.3
Wofsy, C.4
Goldstein, B.5
-
2
-
-
58149280299
-
T-cell receptor binding affinities and kinetics: Impact on T-cell activity and specificity
-
doi:10.1111/j.1365-2567.2008.03015.x
-
Stone, J., Chervin, A. & Kranz, D. 2009 T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity. Immunology 126, 165-176. (doi:10.1111/j.1365-2567.2008.03015.x)
-
(2009)
Immunology
, vol.126
, pp. 165-176
-
-
Stone, J.1
Chervin, A.2
Kranz, D.3
-
3
-
-
77958127055
-
Functional development of the T Cell receptor for antigen
-
doi:10.1016/S1877-1173(10)92004-8
-
Ebert, P., Li, Q., Huppa, J. & Davis, M. 2010 Functional development of the T Cell receptor for antigen. Prog. Mol. Biol. Trans. Sci. 92, 65-100. (doi:10.1016/S1877-1173(10)92004-8)
-
(2010)
Prog. Mol. Biol. Trans. Sci.
, vol.92
, pp. 65-100
-
-
Ebert, P.1
Li, Q.2
Huppa, J.3
Davis, M.4
-
4
-
-
55949095006
-
How the thymus designs antigen-specific and self-tolerant T cell receptor sequences
-
doi:10.1073/pnas.0808081105
-
Košmrlj, A., Jha, A., Huseby, E., Kardar, M. &Chakraborty, A. 2008 How the thymus designs antigen-specific and self-tolerant T cell receptor sequences. Proc. Natl Acad. Sci. USA 105, 16 671-16 676. (doi:10.1073/pnas. 0808081105)
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 16671-16676
-
-
Košmrlj, A.1
Jha, A.2
Huseby, E.3
Kardar, M.4
Chakraborty, A.5
-
5
-
-
0003104975
-
A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists
-
doi:10.1016/S1074-7613(00)80309-X
-
Lyons, D. S., Lieberman, S. A., Hampl, J., Boniface, J. J, Chien, Y., Berg, L. J. & Davis, M. M. 1996 A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists. Immunity 5, 53-61. (doi:10.1016/S1074-7613(00)80309-X)
-
(1996)
Immunity
, vol.5
, pp. 53-61
-
-
Lyons, D.S.1
Lieberman, S.A.2
Hampl, J.3
Boniface, J.J.4
Chien, Y.5
Berg, L.J.6
Davis, M.M.7
-
6
-
-
0033534678
-
From TCR engagement to T cell activation: A kinetic view of T cell behavior
-
doi:10.1016/S0092-8674(00)80952-6
-
Lanzavecchia, A., Lezzi, G. & Viola, A. 1999 From TCR engagement to T cell activation: a kinetic view of T cell behavior. Cell 96, 1-4. (doi:10.1016/S0092-8674(00)80952-6)
-
(1999)
Cell
, vol.96
, pp. 1-4
-
-
Lanzavecchia, A.1
Lezzi, G.2
Viola, A.3
-
7
-
-
0346521283
-
Making sense of mass destruction: Quantitating MHC class I antigen presentation
-
doi:10.1038/nri1250
-
Yewdell, J., Reits, E. & Neefjes, J. 2003 Making sense of mass destruction: quantitating MHC class I antigen presentation. Nat. Rev. Immunol. 3, 952-961. (doi:10.1038/nri1250)
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 952-961
-
-
Yewdell, J.1
Reits, E.2
Neefjes, J.3
-
8
-
-
0033399166
-
Quantitative aspects of T cell activation-peptide generation and editing by MHC class I molecules
-
doi:10.1006/smim.1999.0195
-
Stevanovic, S. & Schild, H. 1999 Quantitative aspects of T cell activation-peptide generation and editing by MHC class I molecules. Semin. Immunol. 11, 375-384. (doi:10.1006/smim.1999.0195)
-
(1999)
Semin. Immunol.
, vol.11
, pp. 375-384
-
-
Stevanovic, S.1
Schild, H.2
-
9
-
-
0027399243
-
Peptides naturally presented by MHC class I molecules
-
doi:10.1146/annurev.iy.11.040193.001241
-
Rammensee, H., Falk, K. & Rötzschk, O. 1993 Peptides naturally presented by MHC class I molecules. Annu. Rev. Immunol. 11, 213-244. (doi:10.1146/annurev.iy.11.040193.001241)
-
(1993)
Annu. Rev. Immunol.
, vol.11
, pp. 213-244
-
-
Rammensee, H.1
Falk, K.2
Rötzschk, O.3
-
10
-
-
0026507564
-
Characterization of peptides bound to the class I MHC molecule HLA-A2. 1 by mass spectrometry
-
doi:10.1126/ science.1546328
-
Hunt, D., Henderson, R., Shabanowitz, J., Sakaguchi, K., Michel, H., Sevilir, N., Cox, A., Appella, E. & Engelhard, V. 1992 Characterization of peptides bound to the class I MHC molecule HLA-A2. 1 by mass spectrometry. Science 255, 1261-1263. (doi:10.1126/ science.1546328)
-
(1992)
Science
, vol.255
, pp. 1261-1263
-
-
Hunt, D.1
Henderson, R.2
Shabanowitz, J.3
Sakaguchi, K.4
Michel, H.5
Sevilir, N.6
Cox, A.7
Appella, E.8
Engelhard, V.9
-
11
-
-
0026335733
-
An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein
-
doi:10.1073/pnas.88.24.11276
-
Tsomides, T., Walker, B. & Eisen, H. 1991 An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein. Proc. Natl Acad. Sci USA 88, 11 276-11 280.(doi:10.1073/pnas.88.24. 11276)
-
(1991)
Proc. Natl Acad. Sci USA
, vol.88
, pp. 11276-11280
-
-
Tsomides, T.1
Walker, B.2
Eisen, H.3
-
12
-
-
67651177609
-
Dead man walking: How thymocytes scan the medulla
-
doi:10.1038/ni0809-809
-
Klein, L. 2009 Dead man walking: how thymocytes scan the medulla. Nat. Immunol. 10, 809-811. (doi:10.1038/ni0809-809)
-
(2009)
Nat. Immunol.
, vol.10
, pp. 809-811
-
-
Klein, L.1
-
13
-
-
76149086153
-
Thymic development beyond β-selection requires phosphatidylinositol 3-kinase activation by CXCR4
-
doi:10.1084/jem.20091430
-
Janas, M., Varano, G., Gudmundsson, K., Noda, M., Nagasawa, T. & Turner, M. 2010 Thymic development beyond β-selection requires phosphatidylinositol 3-kinase activation by CXCR4. J. Exp. Med. 207, 247-261. (doi:10.1084/jem.20091430)
-
(2010)
J. Exp. Med.
, vol.207
, pp. 247-261
-
-
Janas, M.1
Varano, G.2
Gudmundsson, K.3
Noda, M.4
Nagasawa, T.5
Turner, M.6
-
14
-
-
0033581935
-
Selecting and maintaining a diverse T-cell repertoire
-
Goldrath, A. & Bevan, M. 1999 Selecting and maintaining a diverse T-cell repertoire. Nature 402, 6-13.
-
(1999)
Nature
, vol.402
, pp. 6-13
-
-
Goldrath, A.1
Bevan, M.2
-
15
-
-
0038725685
-
Negative selection: Clearing out the bad apples from the T-cell repertoire
-
doi:10.1038/nri1085
-
Palmer, E. 2003 Negative selection: clearing out the bad apples from the T-cell repertoire. Nat. Rev. Immunol. 3, 383-391. (doi:10.1038/nri1085)
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 383-391
-
-
Palmer, E.1
-
16
-
-
33845205745
-
The T-cell antigen receptor: A logical response to an unknown ligand
-
doi:10.1080/10799890600919094
-
Palmer, E. 2006 The T-cell antigen receptor: a logical response to an unknown ligand. J. Recept. Signal Transduct. Res. 26, 367-378. (doi:10.1080/10799890600919094)
-
(2006)
J. Recept. Signal Transduct. Res.
, vol.26
, pp. 367-378
-
-
Palmer, E.1
-
17
-
-
0031048826
-
Quantitative impact of thymic clonal deletion on the T cell repertoire
-
doi:10.1084/jem.185.3.377
-
van Meerwijk, J., Marguerat, S., Lees, R., Germain, R., Fowlkes, B. & MacDonald, H. R. 1997 Quantitative impact of thymic clonal deletion on the T cell repertoire. J. Exp. Med. 185, 377-384. (doi:10.1084/jem.185.3.377)
-
(1997)
J. Exp. Med.
, vol.185
, pp. 377-384
-
-
Van Meerwijk, J.1
Marguerat, S.2
Lees, R.3
Germain, R.4
Fowlkes, B.5
MacDonald, H.R.6
-
18
-
-
34247882592
-
Zoned out: Functional mapping of stromal signaling microenvironments in the thymus
-
doi:10.1146/annurev.immunol.23.021704.115715
-
Petrie, H. & Zúñiga-Pflücker, J. 2007 Zoned out: functional mapping of stromal signaling microenvironments in the thymus. Annu. Rev. Immunol. 25, 649-679. (doi:10.1146/annurev.immunol.23.021704.115715)
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 649-679
-
-
Petrie, H.1
Zúñiga-Pflücker, J.2
-
19
-
-
35748983843
-
A constant affinity threshold for T cell tolerance
-
doi:10.1084/jem.20070254
-
Naeher, D., Daniels, M., Hausmann, B., Guillaume, P., Luescher, I. & Palmer, E. 2007 A constant affinity threshold for T cell tolerance. J. Exp. Med. 204, 2553-2559. (doi:10.1084/jem.20070254)
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2553-2559
-
-
Naeher, D.1
Daniels, M.2
Hausmann, B.3
Guillaume, P.4
Luescher, I.5
Palmer, E.6
-
20
-
-
61349149901
-
Affinity threshold for thymic selection through a T-cell receptor-co-receptor zipper
-
doi:10.1038/nri2469
-
Palmer, E. & Naeher, D. 2009 Affinity threshold for thymic selection through a T-cell receptor-co-receptor zipper. Nat. Rev. Immunol. 9, 207-213. (doi:10.1038/nri2469)
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 207-213
-
-
Palmer, E.1
Naeher, D.2
-
21
-
-
0034907484
-
How much TCR does a T cell need?
-
doi:10.1016/S1074-7613(01)00170-4
-
Labrecque, N., Whitfield, L. S., Obst, R., Waltzinger, C., Benoist, C. & Mathis, D. 2001 How much TCR does a T cell need? Immunity 15, 71-82. (doi:10.1016/S1074-7613(01)00170-4)
-
(2001)
Immunity
, vol.15
, pp. 71-82
-
-
Labrecque, N.1
Whitfield, L.S.2
Obst, R.3
Waltzinger, C.4
Benoist, C.5
Mathis, D.6
-
22
-
-
3442896233
-
T cell avidity determines the level of CTL activation
-
doi:10.1002/eji.200425088
-
Hofmann, M. et al. 2004 T cell avidity determines the level of CTL activation. Eur. J. Immunol. 34, 1798-1806. (doi:10.1002/eji.200425088)
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 1798-1806
-
-
Hofmann, M.1
-
23
-
-
79955541353
-
Strength of TCR-peptide/MHC interactions and in vivo T cell responses
-
doi:10.4049/jimmunol.1003650
-
Corse, E., Gottschalk, R. & Allison, J. 2011 Strength of TCR-peptide/MHC interactions and in vivo T cell responses. J. Immunol. 186, 5039-5045. (doi:10.4049/jimmunol.1003650)
-
(2011)
J. Immunol.
, vol.186
, pp. 5039-5045
-
-
Corse, E.1
Gottschalk, R.2
Allison, J.3
-
24
-
-
0029037210
-
Serial triggering of many T-cell receptors by a few peptide MHC complexes
-
doi:10.1038/ 375148a0
-
Valitutti, S., Müller, S., Cella, M., Padovan, E. & Lanzavecchia, A. 1995 Serial triggering of many T-cell receptors by a few peptide MHC complexes. Nature 375, 148-151. (doi:10.1038/ 375148a0)
-
(1995)
Nature
, vol.375
, pp. 148-151
-
-
Valitutti, S.1
Müller, S.2
Cella, M.3
Padovan, E.4
Lanzavecchia, A.5
-
25
-
-
78649855808
-
The space and time frames of T cell activation at the immunological synapse
-
doi:10.1016/j.febslet.2010.10.010
-
Valitutti, S., Coombs, D. & Dupré, L. 2010 The space and time frames of T cell activation at the immunological synapse. FEBS lett. 584, 4851-4857. (doi:10.1016/j.febslet.2010.10.010)
-
(2010)
FEBS Lett.
, vol.584
, pp. 4851-4857
-
-
Valitutti, S.1
Coombs, D.2
Dupré, L.3
-
26
-
-
0030176270
-
Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response
-
doi:10.1016/S1074-7613(00)80483-5
-
Sykulev, Y., Joo, M., Vturina, I., Tsomides, T. & Eisen, H. 1996 Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response. Immunity 4, 565-571. (doi:10.1016/S1074-7613(00) 80483-5)
-
(1996)
Immunity
, vol.4
, pp. 565-571
-
-
Sykulev, Y.1
Joo, M.2
Vturina, I.3
Tsomides, T.4
Eisen, H.5
-
27
-
-
0037167816
-
Direct observation of ligand recognition by T cells
-
doi:10.1038/nature01076
-
Irvine, D. J, Purbhoo, M. A., Krogsgaard, M. & Davis, M. M 2002 Direct observation of ligand recognition by T cells. Nature 419, 845-849. (doi:10.1038/nature01076)
-
(2002)
Nature
, vol.419
, pp. 845-849
-
-
Irvine, D.J.1
Purbhoo, M.A.2
Krogsgaard, M.3
Davis, M.M.4
-
28
-
-
0346244099
-
T-cell-antigen recognition and the immunological synapse
-
doi:10.1038/nri1245
-
Huppa, J. B. & Davis, M. M. 2003 T-cell-antigen recognition and the immunological synapse. Nat. Rev. Immunol. 3, 973-983. (doi:10.1038/nri1245)
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 973-983
-
-
Huppa, J.B.1
Davis, M.M.2
-
29
-
-
0034903068
-
The impact of duration versus extent of TCR occupancy on T cell activation: A revision of the kinetic proofreading model
-
doi:10.1016 /S1074-7613(01)00173-X
-
Rosette, C., Werlen, G., Daniels, M., Holman, P., Alam, S., Travers, P. J., Gascoigne, N. R. J., Palmer, E. & Jameson, S. C. 2001 The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model. Immunity 15, 59-70. (doi:10.1016 /S1074-7613(01)00173-X)
-
(2001)
Immunity
, vol.15
, pp. 59-70
-
-
Rosette, C.1
Werlen, G.2
Daniels, M.3
Holman, P.4
Alam, S.5
Travers, P.J.6
Gascoigne, N.R.J.7
Palmer, E.8
Jameson, S.C.9
-
30
-
-
79958213129
-
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation
-
doi:10.1126/scisignal.2001430
-
Dushek, O. et al. 2011 Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation. Sci. Signal. 4, ra39. (doi:10.1126/scisignal.2001430)
-
(2011)
Sci. Signal.
, vol.4
-
-
Dushek, O.1
-
31
-
-
58249092059
-
Digital signaling and hysteresis characterize ras activation in lymphoid cells
-
doi:10.1016/j.cell.2008.11.051
-
Das, J., Ho, M., Zikherman, J., Govern, C., Yang, M., Weiss, A., Chakraborty, A. K. & Roose, J. P. 2009 Digital signaling and hysteresis characterize ras activation in lymphoid cells. Cell 136, 337-351. (doi:10.1016/j.cell.2008.11.051)
-
(2009)
Cell
, vol.136
, pp. 337-351
-
-
Das, J.1
Ho, M.2
Zikherman, J.3
Govern, C.4
Yang, M.5
Weiss, A.6
Chakraborty, A.K.7
Roose, J.P.8
-
32
-
-
77951669881
-
Statistical mechanical concepts in immunology
-
doi:10.1146/annurev.physchem.59.032607.093537
-
Chakraborty, A. & Košmrlj, A. 2010 Statistical mechanical concepts in immunology. Annu. Rev. Phys. Chem. 61, 283-303. (doi:10.1146/ annurev.physchem.59.032607.093537)
-
(2010)
Annu. Rev. Phys. Chem.
, vol.61
, pp. 283-303
-
-
Chakraborty, A.1
Košmrlj, A.2
-
33
-
-
72949108077
-
Pairing computation with experimentation: A powerful coupling for understanding T cell signalling
-
doi:10.1038/nri2688
-
Chakraborty, A. & Das, J. 2010 Pairing computation with experimentation: a powerful coupling for understanding T cell signalling. Nat. Rev. Immunol. 10, 59-71. (doi:10.1038/nri2688)
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 59-71
-
-
Chakraborty, A.1
Das, J.2
-
34
-
-
33947268563
-
Quantitative theories of T-cell responsiveness
-
doi:10.1111/j.1600-065X.2006.00491.x
-
Van Den Berg, H. & Rand, D. 2007 Quantitative theories of T-cell responsiveness. Immunol. Rev. 216, 81-92. (doi:10.1111/j.1600-065X.2006.00491.x)
-
(2007)
Immunol. Rev.
, vol.216
, pp. 81-92
-
-
Van Den Berg, H.1
Rand, D.2
-
35
-
-
78650599246
-
Mechanisms for T cell receptor triggering
-
doi:10.1038/nri2887
-
van der Merwe, P. & Dushek, O. 2010 Mechanisms for T cell receptor triggering. Nat. Rev. Immunol. 11, 47-55. (doi:10.1038/nri2887)
-
(2010)
Nat. Rev. Immunol.
, vol.11
, pp. 47-55
-
-
Van Der Merwe, P.1
Dushek, O.2
-
36
-
-
0001596858
-
Kinetics of small systems. I
-
doi:10.1063/1.1733676
-
McQuarrie, D. 1963 Kinetics of small systems. I. J. Chem. Phys. 38, 433-436. (doi:10.1063/1.1733676)
-
(1963)
J. Chem. Phys.
, vol.38
, pp. 433-436
-
-
McQuarrie, D.1
-
37
-
-
36849118694
-
Kinetics of small systems. II
-
doi:10.1063/1.1724926
-
McQuarrie, D., Jachimowski, C. & Russell, M. 1964 Kinetics of small systems. II. J. Chem. Phys. 40, 2914-2921. (doi:10.1063/1.1724926)
-
(1964)
J. Chem. Phys.
, vol.40
, pp. 2914-2921
-
-
McQuarrie, D.1
Jachimowski, C.2
Russell, M.3
-
38
-
-
0001601301
-
Stochastic approach to chemical kinetics
-
doi:10.2307/3212214
-
McQuarrie, D. 1967 Stochastic approach to chemical kinetics. J. Appl. Probab. 4, 413-478. (doi:10.2307/3212214)
-
(1967)
J. Appl. Probab.
, vol.4
, pp. 413-478
-
-
McQuarrie, D.1
-
39
-
-
84874216929
-
A review of mathematical models for T cell receptor triggering and antigen discrimination
-
eds C. Molina-París & G. Lythe, Berlin, Germany: Springer
-
Coombs, D., Dushek, O. & Merwe, P. 2011 A review of mathematical models for T cell receptor triggering and antigen discrimination. In Mathematical models and immune cell biology (eds C. Molina-París & G. Lythe), pp. 25-45. Berlin, Germany: Springer.
-
(2011)
Mathematical Models and Immune Cell Biology
, pp. 25-45
-
-
Coombs, D.1
Dushek, O.2
Merwe, P.3
-
40
-
-
0034753172
-
T-cell activation by soluble MHC oligomers can be described by a two-parameter binding model
-
doi:10.1016/S0006-3495(01)75899-7
-
Stone, J., Cochran, J. & Stern, L. 2001 T-cell activation by soluble MHC oligomers can be described by a two-parameter binding model. Biophys. J. 81, 2547-2557. (doi:10.1016/S0006-3495(01)75899-7)
-
(2001)
Biophys. J.
, vol.81
, pp. 2547-2557
-
-
Stone, J.1
Cochran, J.2
Stern, L.3
-
41
-
-
83755178630
-
Interaction of streptavidin-based peptide-MHC oligomers (tetramers) with cellsurface TCRs
-
doi:10.4049/jimmunol.1101734
-
Stone, J., Artyomov, M., Chervin, A., Chakraborty, A., Eisen, H. & Kranz, D. M. 2011 Interaction of streptavidin-based peptide-MHC oligomers (tetramers) with cellsurface TCRs. J. Immunol. 187, 6281-6290. (doi:10.4049/jimmunol.1101734)
-
(2011)
J. Immunol.
, vol.187
, pp. 6281-6290
-
-
Stone, J.1
Artyomov, M.2
Chervin, A.3
Chakraborty, A.4
Eisen, H.5
Kranz, D.M.6
-
42
-
-
76949085272
-
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time
-
doi:10.1016/j.immuni.2009.11.013
-
Aleksic, M., Dushek, O., Zhang, H., Shenderov, E., Chen, J., Cerundolo, V., Coombs, D. & Anton van der Merwe, P. 2010 Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time. Immunity 32, 163-174. (doi:10.1016/j.immuni.2009.11.013)
-
(2010)
Immunity
, vol.32
, pp. 163-174
-
-
Aleksic, M.1
Dushek, O.2
Zhang, H.3
Shenderov, E.4
Chen, J.5
Cerundolo, V.6
Coombs, D.7
Anton Van Der Merwe, P.8
-
43
-
-
77952712883
-
Fast on-rates allow short dwell time ligands to activate T cells
-
doi:10.1073/pnas.1000966107
-
Govern, C., Paczosa, M., Chakraborty, A. & Huseby, E. 2010 Fast on-rates allow short dwell time ligands to activate T cells. Proc. Natl Acad. Sci. 107, 8724-8729. (doi:10.1073/pnas.1000966107)
-
(2010)
Proc. Natl Acad. Sci.
, vol.107
, pp. 8724-8729
-
-
Govern, C.1
Paczosa, M.2
Chakraborty, A.3
Huseby, E.4
-
44
-
-
0003519552
-
-
Oxford, UK: Oxford University Press
-
Lauffenburger, D. & Linderman, J. 1996 Receptors: models for binding, trafficking, and signaling. Oxford, UK: Oxford University Press.
-
(1996)
Receptors: Models for Binding, Trafficking, and Signaling
-
-
Lauffenburger, D.1
Linderman, J.2
-
45
-
-
30644464347
-
A mathematical model for crystal growth by aggregation of precursor metastable nanoparticles
-
doi:10.1021/jp0537299
-
Drews, T., Katsoulakis, M. & Tsapatsis, M. 2005 A mathematical model for crystal growth by aggregation of precursor metastable nanoparticles. J. Phys. Chem. B 109, 23879-23887.(doi:10.1021/jp0537299)
-
(2005)
J. Phys. Chem. B
, vol.109
, pp. 23879-23887
-
-
Drews, T.1
Katsoulakis, M.2
Tsapatsis, M.3
-
46
-
-
1542547925
-
A metabolic force for gene clustering
-
doi:10.1016/j.bulm.2003.09.008
-
Svetic, R., MacCluer, C., Buckley, C., Smythe, K. & Jackson, J. 2004 A metabolic force for gene clustering. Bull. Math. Biol. 66, 559-581. (doi:10.1016/j.bulm.2003.09.008)
-
(2004)
Bull. Math. Biol.
, vol.66
, pp. 559-581
-
-
Svetic, R.1
MacCluer, C.2
Buckley, C.3
Smythe, K.4
Jackson, J.5
-
47
-
-
0036204115
-
STOCKS: STOChastic Kinetic Simulations of biochemical systems with Gillespie algorithm
-
doi:10.1093/bioinformatics/18.3.470
-
Kierzek, A. 2002 STOCKS: STOChastic Kinetic Simulations of biochemical systems with Gillespie algorithm. Bioinformatics 18, 470-481. (doi:10.1093/bioinformatics/18.3.470)
-
(2002)
Bioinformatics
, vol.18
, pp. 470-481
-
-
Kierzek, A.1
-
48
-
-
79960137914
-
Scaffold-mediated nucleation of protein signaling complexes: Elementary principles
-
doi:10.1016/j.mbs.2011.06.003
-
Yang, J. & Hlavacek, W. 2011 Scaffold-mediated nucleation of protein signaling complexes: elementary principles. Math. Biosci. 232, 164-173. (doi:10.1016/j.mbs.2011.06.003)
-
(2011)
Math. Biosci.
, vol.232
, pp. 164-173
-
-
Yang, J.1
Hlavacek, W.2
-
52
-
-
27844541328
-
Modeling T cell antigen discrimination based on feedback control of digital ERK responses
-
doi:10.1371/journal.pbio.0030356
-
Altan-Bonnet, G. & Germain, R. 2005 Modeling T cell antigen discrimination based on feedback control of digital ERK responses. PLoS Biol. 3, e356. (doi:10.1371/journal.pbio.0030356)
-
(2005)
PLoS Biol.
, vol.3
-
-
Altan-Bonnet, G.1
Germain, R.2
-
53
-
-
49049088099
-
Stochastic effects and bistability in T cell receptor signaling
-
doi:10.1016/j.jtbi.2008.05.001
-
Lipniacki, T., Hat, B., Faeder, J. R. & Hlavacek, W. S. 2008 Stochastic effects and bistability in T cell receptor signaling. J. Theor. Biol. 254, 110-122. (doi:10.1016/j.jtbi.2008.05.001)
-
(2008)
J. Theor. Biol.
, vol.254
, pp. 110-122
-
-
Lipniacki, T.1
Hat, B.2
Faeder, J.R.3
Hlavacek, W.S.4
-
55
-
-
77249114784
-
TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity
-
doi:10.1038/nature08746
-
Huppa, J., Axmann, M., Mörtelmaier, M., Lillemeier, B., Newell, E., Brameshuber, M., Klein, L. O., Schüz, G. J. & Davis, M. M. 2010 TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity. Nature 463, 963-967. (doi:10.1038/nature08746)
-
(2010)
Nature
, vol.463
, pp. 963-967
-
-
Huppa, J.1
Axmann, M.2
Mörtelmaier, M.3
Lillemeier, B.4
Newell, E.5
Brameshuber, M.6
Klein, L.O.7
Schüz, G.J.8
Davis, M.M.9
-
56
-
-
77950809538
-
The kinetics of two dimensional TCR and pMHC interactions determine T cell responsiveness
-
doi:10.1038/nature08944
-
Huang, J., Zarnitsyna, V., Liu, B., Edwards, L., Jiang, N., Evavold, B. D. & Zhu, C. 2010 The kinetics of two dimensional TCR and pMHC interactions determine T cell responsiveness. Nature 464, 932-936. (doi:10.1038/nature08944)
-
(2010)
Nature
, vol.464
, pp. 932-936
-
-
Huang, J.1
Zarnitsyna, V.2
Liu, B.3
Edwards, L.4
Jiang, N.5
Evavold, B.D.6
Zhu, C.7
-
59
-
-
36749092326
-
Memory in receptor-ligand-mediated cell adhesion
-
doi:10.1073/pnas.0704811104
-
Zarnitsyna, V., Huang, J., Zhang, F., Chien, Y., Leckband, D. & Zhu, C. 2007 Memory in receptor-ligand-mediated cell adhesion. Proc. Natl Acad. Sci. USA 104, 18037-18042.(doi:10.1073/pnas.0704811104)
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 18037-18042
-
-
Zarnitsyna, V.1
Huang, J.2
Zhang, F.3
Chien, Y.4
Leckband, D.5
Zhu, C.6
-
60
-
-
84856020544
-
Kinetics and mechanics of two-dimensional interactions between T cell receptors and different activating ligands
-
doi:10.1016/j.bpj.2011.11.4018
-
Robert, P., Aleksic, M., Dushek, O., Cerundolo, V., Bongrand, P. & van der Merwe, P. A. 2012 Kinetics and mechanics of two-dimensional interactions between T cell receptors and different activating ligands. Biophys. J. 102, 248-257. (doi:10.1016/j.bpj.2011.11.4018)
-
(2012)
Biophys. J.
, vol.102
, pp. 248-257
-
-
Robert, P.1
Aleksic, M.2
Dushek, O.3
Cerundolo, V.4
Bongrand, P.5
Van Der Merwe, P.A.6
-
61
-
-
0029063148
-
Kinetic proofreading in T-cell receptor signal transduction
-
doi:10.1073/pnas.92.11.5042
-
Mckeithan, T. 1995 Kinetic proofreading in T-cell receptor signal transduction. Proc. Natl Acad. Sci USA 92, 5042-5046. (doi:10.1073/pnas.92.11. 5042)
-
(1995)
Proc. Natl Acad. Sci USA
, vol.92
, pp. 5042-5046
-
-
Mckeithan, T.1
-
62
-
-
66249102308
-
Multisite protein phosphorylation-from molecular mechanisms to kinetic models
-
doi:10.1111/j.1742-4658.2009.07027.x
-
Salazar, C. & Höfer, T. 2009 Multisite protein phosphorylation-from molecular mechanisms to kinetic models. FEBS J. 276, 3177-3198. (doi:10.1111/j.1742-4658.2009.07027.x)
-
(2009)
FEBS J.
, vol.276
, pp. 3177-3198
-
-
Salazar, C.1
Höfer, T.2
-
63
-
-
73449105773
-
A role for rebinding in rapid and reliable T cell responses to antigen
-
doi:10.1371/journal.pcbi.1000578
-
Dushek, O., Das, R. & Coombs, D. 2009 A role for rebinding in rapid and reliable T cell responses to antigen. PLoS Comput. Biol. 5, e1000578. (doi:10.1371/journal.pcbi.1000578)
-
(2009)
PLoS Comput. Biol.
, vol.5
-
-
Dushek, O.1
Das, R.2
Coombs, D.3
-
64
-
-
85012563943
-
T-cell receptor binding kinetics in T-cell development and activation
-
Gascoigne, N., Zal, T. & Alam, S. 2001 T-cell receptor binding kinetics in T-cell development and activation. Expert Rev. Mol. Med. 2, 1-17.
-
(2001)
Expert Rev. Mol. Med.
, vol.2
, pp. 1-17
-
-
Gascoigne, N.1
Zal, T.2
Alam, S.3
-
65
-
-
0037459321
-
Signaling life and death in the thymus: Timing is everything
-
doi:10.1126/science.1067833
-
Werlen, G., Hausmann, B., Naeher, D. & Palmer, E. 2003 Signaling life and death in the thymus: timing is everything. Science 299, 1859-1863. (doi:10.1126/science.1067833)
-
(2003)
Science
, vol.299
, pp. 1859-1863
-
-
Werlen, G.1
Hausmann, B.2
Naeher, D.3
Palmer, E.4
-
66
-
-
0030806085
-
In thymic selection, peptide diversity minireview gives and takes away
-
doi:10.1016/ S1074-7613(00)80520-8
-
Bevan, M. 1997 In thymic selection, peptide diversity minireview gives and takes away. Immunity 7, 175-178. (doi:10.1016/ S1074-7613(00)80520-8)
-
(1997)
Immunity
, vol.7
, pp. 175-178
-
-
Bevan, M.1
-
67
-
-
0030975532
-
Antigen localisation regulates immune responses in a dose-and time-dependent fashion: A geographical view of immune reactivity
-
doi:10.1111/j.1600-065X.1997.tb00969.x
-
Zinkernagel, R., Ehl, S., Aichele, P., Oehen, S., Kündig, T. &Hengartner, H. 1997 Antigen localisation regulates immune responses in a dose-and time-dependent fashion: a geographical view of immune reactivity. Immunol. Rev. 156, 199-209. (doi:10.1111/j.1600-065X.1997.tb00969.x)
-
(1997)
Immunol. Rev.
, vol.156
, pp. 199-209
-
-
Zinkernagel, R.1
Ehl, S.2
Aichele, P.3
Oehen, S.4
Kündig, T.5
Hengartner, H.6
-
68
-
-
33748452685
-
T-cell activation: A queuing theory analysis at low agonist density
-
doi:10.1529/biophysj.105.066001
-
Wedagedera, J. & Burroughs, N. 2006 T-cell activation: A queuing theory analysis at low agonist density. Biophys. J. 91, 1604-1618. (doi:10.1529/biophysj.105.066001)
-
(2006)
Biophys. J.
, vol.91
, pp. 1604-1618
-
-
Wedagedera, J.1
Burroughs, N.2
-
69
-
-
43649103144
-
Analysis of serial engagement and peptide-MHC transport in T cell receptor microclusters
-
doi:10.1529/biophysj.107.116897
-
Dushek, O. & Coombs, D. 2008 Analysis of serial engagement and peptide-MHC transport in T cell receptor microclusters. Biophys. J. 94, 3447-3460. (doi:10.1529/biophysj.107.116897)
-
(2008)
Biophys. J.
, vol.94
, pp. 3447-3460
-
-
Dushek, O.1
Coombs, D.2
-
71
-
-
33645429016
-
Exact stochastic simulation of coupled chemical reactions
-
doi:10.1021/ j100540a008
-
Gillespie, D. 1977 Exact stochastic simulation of coupled chemical reactions. J. Phys. Chem. 81, 2340-2361. (doi:10.1021/ j100540a008)
-
(1977)
J. Phys. Chem.
, vol.81
, pp. 2340-2361
-
-
Gillespie, D.1
-
72
-
-
44049109914
-
A rigorous derivation of the chemical master equation
-
doi:10.1016/0378-4371(92)90283-V
-
Gillespie, D. 1992 A rigorous derivation of the chemical master equation. Physica A 188, 404-425. (doi:10.1016/0378-4371(92)90283-V)
-
(1992)
Physica A
, vol.188
, pp. 404-425
-
-
Gillespie, D.1
|