-
1
-
-
0033581935
-
Selecting and maintaining a diverse T-cell repertoire
-
Goldrath AW, Bevan MJ. Selecting and maintaining a diverse T-cell repertoire. Nature 1999;402:255-262.
-
(1999)
Nature
, vol.402
, pp. 255-262
-
-
Goldrath, A.W.1
Bevan, M.J.2
-
3
-
-
0033615678
-
A direct estimate of the human α-β T cell receptor diversity
-
Arstila TP, Casrouge A, Baron B, Even J, Kanellopoulos J, Kourilsky P. A direct estimate of the human α-β T cell receptor diversity. Science 1999;286:958-961.
-
(1999)
Science
, vol.286
, pp. 958-961
-
-
Arstila, T.P.1
Casrouge, A.2
Baron, B.3
Even, J.4
Kanellopoulos, J.5
Kourilsky, P.6
-
5
-
-
0023663430
-
T cell tolerance by clonal elimination in the thymus
-
Kappler JW, Roehm N, Marrack P. T cell tolerance by clonal elimination in the thymus. Cell 1987;49:273-280.
-
(1987)
Cell
, vol.49
, pp. 273-280
-
-
Kappler, J.W.1
Roehm, N.2
Marrack, P.3
-
6
-
-
0023900635
-
Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes
-
Kisielow P, Blüthmann H, Staerz UD, Steinmetz M, von Boehmer H. Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes. Nature 1988;333:742-746.
-
(1988)
Nature
, vol.333
, pp. 742-746
-
-
Kisielow, P.1
Blüthmann, H.2
Staerz, U.D.3
Steinmetz, M.4
von Boehmer, H.5
-
7
-
-
0033136289
-
Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo
-
Laufer TM, Fan L, Glimcher LH. Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo. J Immunol 1999;162:5078-5084.
-
(1999)
J Immunol
, vol.162
, pp. 5078-5084
-
-
Laufer, T.M.1
Fan, L.2
Glimcher, L.H.3
-
9
-
-
0033738329
-
The role of different subsets of T regulatory cells in controlling autoimmunity
-
Roncarolo M-G, Levings MK. The role of different subsets of T regulatory cells in controlling autoimmunity. Curr Opin Immunol 2000;12:676-683.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 676-683
-
-
Roncarolo, M.-G.1
Levings, M.K.2
-
10
-
-
1342345915
-
CD86 and CD80 differentially modulate the suppressive function of human regulatory T cells
-
Zheng Y, Manzotti CN, Liu M, Burke F, Mead KI, Sansom DM. CD86 and CD80 differentially modulate the suppressive function of human regulatory T cells. J Immunol 2004;172:2778-2784.
-
(2004)
J Immunol
, vol.172
, pp. 2778-2784
-
-
Zheng, Y.1
Manzotti, C.N.2
Liu, M.3
Burke, F.4
Mead, K.I.5
Sansom, D.M.6
-
11
-
-
0035059417
-
Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation
-
Salomon B, Bluestone JA. Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation. Annu Rev Immunol 2001;19:225-252.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 225-252
-
-
Salomon, B.1
Bluestone, J.A.2
-
12
-
-
0030694234
-
The emerging role of CTLA-4 as an immune attenuator
-
Thompson CB, Allison JP. The emerging role of CTLA-4 as an immune attenuator. Immunity 1997;7:445-450.
-
(1997)
Immunity
, vol.7
, pp. 445-450
-
-
Thompson, C.B.1
Allison, J.P.2
-
13
-
-
0043268924
-
Dynamics of cell surface molecules during T cell recognition
-
Davis MM, et al. Dynamics of cell surface molecules during T cell recognition. Annu Rev Biochem 2003;72:717-742.
-
(2003)
Annu Rev Biochem
, vol.72
, pp. 717-742
-
-
Davis, M.M.1
-
14
-
-
0032171644
-
A very high level of crossreactivity is an essential feature of the T-cell receptor
-
Mason D. A very high level of crossreactivity is an essential feature of the T-cell receptor. Immunol Today 1998;19:395-404.
-
(1998)
Immunol Today
, vol.19
, pp. 395-404
-
-
Mason, D.1
-
15
-
-
0034659119
-
Autoantigen-responsive T cell clones demonstrate unfocused TCR cross-reactivity toward multiple related ligands: Implications for autoimmunity
-
Abderson AC, et al. Autoantigen-responsive T cell clones demonstrate unfocused TCR cross-reactivity toward multiple related ligands: implications for autoimmunity. Cell Immunol 2000;202:88-96.
-
(2000)
Cell Immunol
, vol.202
, pp. 88-96
-
-
Abderson, A.C.1
-
16
-
-
0036467394
-
The specificity of TCR.pMCH interaction
-
Rudolph MG, Wilson IA. The specificity of TCR.pMCH interaction. Curr Opin Immunol 2002;14:52-65.
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 52-65
-
-
Rudolph, M.G.1
Wilson, I.A.2
-
17
-
-
0032549142
-
Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen
-
Garcia KC, et al. Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen. Science 1998;279:1166-1172.
-
(1998)
Science
, vol.279
, pp. 1166-1172
-
-
Garcia, K.C.1
-
18
-
-
0030925578
-
Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone
-
Hemmer B, et al. Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone. J Exp Med 1997;185:1651-1659.
-
(1997)
J Exp Med
, vol.185
, pp. 1651-1659
-
-
Hemmer, B.1
-
19
-
-
0031966527
-
Probing degeneracy in T-cell recognition using peptide combinatorial libraries
-
Hemmer B, Vergelli M, Pinilla C, Houghten R, Martin R. Probing degeneracy in T-cell recognition using peptide combinatorial libraries. Immunol Today 1998;19:163-168.
-
(1998)
Immunol Today
, vol.19
, pp. 163-168
-
-
Hemmer, B.1
Vergelli, M.2
Pinilla, C.3
Houghten, R.4
Martin, R.5
-
20
-
-
0030058657
-
The repertoire of T cells shaped by a single MHC/peptide ligand
-
Ignatowicz L, Kappler J, Marrack P. The repertoire of T cells shaped by a single MHC/peptide ligand. Cell 1996;84:521-529.
-
(1996)
Cell
, vol.84
, pp. 521-529
-
-
Ignatowicz, L.1
Kappler, J.2
Marrack, P.3
-
21
-
-
0029961893
-
Structural basis for T cell recognition of altered peptide ligands: A single T cell receptor can productively recognize a large continuum of related ligands
-
Kersh GH, Allen PM. Structural basis for T cell recognition of altered peptide ligands: a single T cell receptor can productively recognize a large continuum of related ligands. J Exp Med 1996;184:1259-1268.
-
(1996)
J Exp Med
, vol.184
, pp. 1259-1268
-
-
Kersh, G.H.1
Allen, P.M.2
-
22
-
-
0031817312
-
Glimpses at the recognition of peptide/MHC complexes by T-cell antigen receptors
-
Mazza G, et al. Glimpses at the recognition of peptide/MHC complexes by T-cell antigen receptors. Immunol Rev 1998;163:187-196.
-
(1998)
Immunol Rev
, vol.163
, pp. 187-196
-
-
Mazza, G.1
-
23
-
-
0028017808
-
A differential-avidity model for T-cell selection
-
Ashton-Rickardt PG, Tonegawa S. A differential-avidity model for T-cell selection. Immunol Today 1994;15:362-366.
-
(1994)
Immunol Today
, vol.15
, pp. 362-366
-
-
Ashton-Rickardt, P.G.1
Tonegawa, S.2
-
24
-
-
0034630306
-
Differential expansion and survival of high and low avidity cytotoxic T cell populations during the immune response to a viral infection
-
Alexander-Miller MA. Differential expansion and survival of high and low avidity cytotoxic T cell populations during the immune response to a viral infection. Cell Immunol 2000;201:58-62.
-
(2000)
Cell Immunol
, vol.201
, pp. 58-62
-
-
Alexander-Miller, M.A.1
-
25
-
-
11144356391
-
High vaccination efficiency of low-affinity epitopes in antitumor immunotherapy
-
Gross D-A, et al. High vaccination efficiency of low-affinity epitopes in antitumor immunotherapy. J Clin Invest 2004;113:425-433.
-
(2004)
J Clin Invest
, vol.113
, pp. 425-433
-
-
Gross, D.-A.1
-
26
-
-
0037340388
-
The nature of molecular recognition by T cells
-
Davis SJ, Ikemizu S, Evans EJ, Fugger L, Bakker TR, van der Merwe PA. The nature of molecular recognition by T cells. Nat Immunol 2003;4:1-8.
-
(2003)
Nat Immunol
, vol.4
, pp. 1-8
-
-
Davis, S.J.1
Ikemizu, S.2
Evans, E.J.3
Fugger, L.4
Bakker, T.R.5
van der Merwe, P.A.6
-
27
-
-
0033399166
-
Quantitative aspects of T cell activation - peptide generation and editing by MHC class I molecule
-
Stevanović S, Schild H. Quantitative aspects of T cell activation - peptide generation and editing by MHC class I molecule. Semin Immunol 1999;11:375-384.
-
(1999)
Semin Immunol
, vol.11
, pp. 375-384
-
-
Stevanović, S.1
Schild, H.2
-
28
-
-
4544382384
-
Discriminating self from nonself with short peptides from large proteomes
-
Burroughs N, Kesxmir C, de Boer R. Discriminating self from nonself with short peptides from large proteomes. Immunogenetics 2004;56:311-320.
-
(2004)
Immunogenetics
, vol.56
, pp. 311-320
-
-
Burroughs, N.1
Kesxmir, C.2
de Boer, R.3
-
29
-
-
0036604916
-
The TCR signalosome: A dynamic structure with expanding complexity
-
Werlen G, Palmer E. The TCR signalosome: a dynamic structure with expanding complexity. Curr Opin Immunol 2002;14:299-305.
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 299-305
-
-
Werlen, G.1
Palmer, E.2
-
30
-
-
33947266978
-
-
New York: Garland Publishing
-
Parham O. The Immue System. New York: Garland Publishing, 2000.
-
(2000)
The Immue System
-
-
Parham, O.1
-
31
-
-
0027399243
-
Peptides naturally presented by MHC class I molecules
-
Rannessee H-G, Falk K, Rotzshke O. Peptides naturally presented by MHC class I molecules. Annu Rev Immunol 1993;11:213-244.
-
(1993)
Annu Rev Immunol
, vol.11
, pp. 213-244
-
-
Rannessee, H.-G.1
Falk, K.2
Rotzshke, O.3
-
33
-
-
0037066427
-
The danger model: A renewed sense of self
-
Matzinger P. The danger model: a renewed sense of self. Science 2002;296:301-305.
-
(2002)
Science
, vol.296
, pp. 301-305
-
-
Matzinger, P.1
-
34
-
-
0035286588
-
Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex
-
Kalergis AM, et al. Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex. Nat Immunol 2001;2:229-234.
-
(2001)
Nat Immunol
, vol.2
, pp. 229-234
-
-
Kalergis, A.M.1
-
35
-
-
0036664812
-
Quantifying the strength of ligand antagonism in TCR triggering
-
van den Berg HA, Burroughs N, Rand DA. Quantifying the strength of ligand antagonism in TCR triggering. Bull Math Biol 2002;64:781-808.
-
(2002)
Bull Math Biol
, vol.64
, pp. 781-808
-
-
van den Berg, H.A.1
Burroughs, N.2
Rand, D.A.3
-
36
-
-
0034613152
-
Dynamics of T lymphocyte responses: Intermediates, effectors, and memory cells
-
Lanzavecchia A, Sallusto F. Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells. Science 2000;290:92-97.
-
(2000)
Science
, vol.290
, pp. 92-97
-
-
Lanzavecchia, A.1
Sallusto, F.2
-
37
-
-
0031557886
-
Modeling T-cell proliferation: An investigation of the consequences of the Hayflick limit
-
Pilyugin S, Mittler J, Antia R. Modeling T-cell proliferation: an investigation of the consequences of the Hayflick limit. J Theor Biol 1997;186:117-129.
-
(1997)
J Theor Biol
, vol.186
, pp. 117-129
-
-
Pilyugin, S.1
Mittler, J.2
Antia, R.3
-
38
-
-
0032827889
-
Competition for antigenic sites during T cell proliferation: A mathematical interpretation of in vitro data
-
Borghans JAM, Taams LS, Wauben MHM, de Boer R. Competition for antigenic sites during T cell proliferation: a mathematical interpretation of in vitro data. Proc Natl Acad Sci USA 1999;96:10782-10787.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10782-10787
-
-
Borghans, J.A.M.1
Taams, L.S.2
Wauben, M.H.M.3
de Boer, R.4
-
39
-
-
0032007065
-
Massive expansion of antigen-specific CD8pT cells during an acute virus infection
-
Butz EA, Bevan MJ. Massive expansion of antigen-specific CD8pT cells during an acute virus infection. Immunity 1998;8:167-175.
-
(1998)
Immunity
, vol.8
, pp. 167-175
-
-
Butz, E.A.1
Bevan, M.J.2
-
40
-
-
0029552310
-
Increased peptide promiscuity provides a rationale for the lack of N regions in the neonatal T cell repertoire
-
Gavin MA, Bevan MJ. Increased peptide promiscuity provides a rationale for the lack of N regions in the neonatal T cell repertoire. Immunity 1995;3:793-800.
-
(1995)
Immunity
, vol.3
, pp. 793-800
-
-
Gavin, M.A.1
Bevan, M.J.2
-
41
-
-
0029965055
-
Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy
-
Alexander-Miller MA, Leggatt GR, Berzofsky JA. Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. Proc Natl Acad Sci USA 1996;93:4102-4107.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4102-4107
-
-
Alexander-Miller, M.A.1
Leggatt, G.R.2
Berzofsky, J.A.3
-
43
-
-
0032410748
-
Models of immune memory: On the role of cross-reactive stimulation, competition, and homeostasis in maintaining immune memory
-
Antia R, Pilyugin SS, Ahmed R. Models of immune memory: on the role of cross-reactive stimulation, competition, and homeostasis in maintaining immune memory. Proc Natl Acad Sci USA 1998;95:14926-14931.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14926-14931
-
-
Antia, R.1
Pilyugin, S.S.2
Ahmed, R.3
-
44
-
-
0034906066
-
Stability of a diverse immunological memory is determined by T cell population dynamics
-
Utzny C, Burroughs NJ. Stability of a diverse immunological memory is determined by T cell population dynamics. Bull Math Biol 2001;63:685-713.
-
(2001)
Bull Math Biol
, vol.63
, pp. 685-713
-
-
Utzny, C.1
Burroughs, N.J.2
-
45
-
-
33746743790
-
Cell death and the maintenance of immunological memory
-
Yates AJ, Callard RE. Cell death and the maintenance of immunological memory. Discr Cont Dynam Sys B 2001;1:43-60.
-
Discr Cont Dynam Sys
, vol.B 2001
, Issue.1
, pp. 43-60
-
-
Yates, A.J.1
Callard, R.E.2
-
46
-
-
0023123622
-
Immunological discrimination between self and non-self by precursor depletion and memory accumulation
-
de Boer RJ, Hogeweg P. Immunological discrimination between self and non-self by precursor depletion and memory accumulation. J Theor Biol 1987;124:343-369.
-
(1987)
J Theor Biol
, vol.124
, pp. 343-369
-
-
de Boer, R.J.1
Hogeweg, P.2
-
48
-
-
0031870528
-
Crossreactivity of the T-cell receptor
-
Borghans J, de Boer RJ. Crossreactivity of the T-cell receptor. Immunol Today 1998;19:428-429.
-
(1998)
Immunol Today
, vol.19
, pp. 428-429
-
-
Borghans, J.1
de Boer, R.J.2
-
49
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
Jordan MS, et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol 2001;2:301-306.
-
(2001)
Nat Immunol
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
-
50
-
-
0035181750
-
Some quantitative aspects of T cell repertoire se-lection: The requirement for regulatory T cells
-
Mason D. Some quantitative aspects of T cell repertoire se-lection: the requirement for regulatory T cells. Immunol Rev 2001;182:80-88.
-
(2001)
Immunol Rev
, vol.182
, pp. 80-88
-
-
Mason, D.1
-
51
-
-
17044454394
-
Inverse correlation between the incidences of autoimmune disease and infection predicted by a model of T cell mediated tolerance
-
León K, Faro J, Lage A, Carneiro J. Inverse correlation between the incidences of autoimmune disease and infection predicted by a model of T cell mediated tolerance. J Autoimmun 2004;22:31-42.
-
(2004)
J Autoimmun
, vol.22
, pp. 31-42
-
-
León, K.1
Faro, J.2
Lage, A.3
Carneiro, J.4
-
52
-
-
5644255710
-
Foreignness as a matter of degree: The relative immunogenicity of peptide/MHC ligands
-
van den Berg HA, Rand DA. Foreignness as a matter of degree: the relative immunogenicity of peptide/MHC ligands. J Theor Biol 2004;231:535-548.
-
(2004)
J Theor Biol
, vol.231
, pp. 535-548
-
-
van den Berg, H.A.1
Rand, D.A.2
-
53
-
-
0037310510
-
Preferential escape of subdominant CD8+T cells during negative selection results in an altered antiviral T cell hierarchy
-
Slifka MK, et al. Preferential escape of subdominant CD8+T cells during negative selection results in an altered antiviral T cell hierarchy. J Immunol 2003;170:1231-1239.
-
(2003)
J Immunol
, vol.170
, pp. 1231-1239
-
-
Slifka, M.K.1
-
54
-
-
0030475056
-
Could endogenous selfpeptides presented by dendritic cells initiate rheumatoid arthritis?
-
Thomas R, Lipsky PE. Could endogenous selfpeptides presented by dendritic cells initiate rheumatoid arthritis? Immunol Today 1996;17:559-564.
-
(1996)
Immunol Today
, vol.17
, pp. 559-564
-
-
Thomas, R.1
Lipsky, P.E.2
-
56
-
-
0035925931
-
A reliable and safe T cell repertoire based on low-affinity T cell receptors
-
van den Berg HA, Rand DA, Burroughs NJ. A reliable and safe T cell repertoire based on low-affinity T cell receptors. J Theor Biol 2001;209:465-486.
-
(2001)
J Theor Biol
, vol.209
, pp. 465-486
-
-
van den Berg, H.A.1
Rand, D.A.2
Burroughs, N.J.3
-
57
-
-
0041620480
-
Antigen presentation on MHC molecules as a diversity filter that enhances immune efficacy
-
van den Berg HA, Rand DA. Antigen presentation on MHC molecules as a diversity filter that enhances immune efficacy. J Theor Biol 2003;224:249-267.
-
(2003)
J Theor Biol
, vol.224
, pp. 249-267
-
-
van den Berg, H.A.1
Rand, D.A.2
-
58
-
-
0034700306
-
Designing lymphocyte functional structure for optimal signal detection: Voilà, T cells
-
Noest AJ. Designing lymphocyte functional structure for optimal signal detection: voilà, T cells. J Theor Biol 2000;207:195-216.
-
(2000)
J Theor Biol
, vol.207
, pp. 195-216
-
-
Noest, A.J.1
-
59
-
-
0344739964
-
Thymic presentation of autoantigens and the efficiency of negative selection
-
van den Berg HA, Molina-París C. Thymic presentation of autoantigens and the efficiency of negative selection. J Theor Med 2003;5:1-22.
-
(2003)
J Theor Med
, vol.5
, pp. 1-22
-
-
van den Berg, H.A.1
Molina-París, C.2
-
60
-
-
0033179679
-
On the role of feedback in promoting conflicting goals of the adaptive immune system
-
Segel LA, Lev Bar-Or R. On the role of feedback in promoting conflicting goals of the adaptive immune system. J Immunol 1999;163:1342-1349.
-
(1999)
J Immunol
, vol.163
, pp. 1342-1349
-
-
Segel, L.A.1
Lev Bar-Or, R.2
-
61
-
-
0033231115
-
Cytokines, chaos, and complexity
-
Callard RE, George AJT, Stark J. Cytokines, chaos, and complexity. Immunity 1999;11:507-513.
-
(1999)
Immunity
, vol.11
, pp. 507-513
-
-
Callard, R.E.1
George, A.J.T.2
Stark, J.3
-
62
-
-
0034699775
-
Cytokine-modulated regulation of helper T cell populations
-
Yates AJ, Bergmann L, van Hemmen C, Stark J, Callard RE. Cytokine-modulated regulation of helper T cell populations. J Theor Biol 2000;205:539-560.
-
(2000)
J Theor Biol
, vol.205
, pp. 539-560
-
-
Yates, A.J.1
Bergmann, L.2
van Hemmen, C.3
Stark, J.4
Callard, R.E.5
-
63
-
-
0037437760
-
Perturbation theory analysis of competition in a heterogeneous population
-
Utzny C, Burroughs NJ. Perturbation theory analysis of competition in a heterogeneous population. Physica D 2003;175:109-126.
-
(2003)
Physica D
, vol.175
, pp. 109-126
-
-
Utzny, C.1
Burroughs, N.J.2
-
64
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
Monks CRF, Freiberg BA, Kupfer H, Sciaky N, Kupfer A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 1998;395:82-86.
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.R.F.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
65
-
-
0033614036
-
Costimulation: Building an immunological synapse
-
Dustin ML, Shaw AA. Costimulation: building an immunological synapse. Science 1999;283:649-650.
-
(1999)
Science
, vol.283
, pp. 649-650
-
-
Dustin, M.L.1
Shaw, A.A.2
-
66
-
-
0033538574
-
The immunological synapse: A molecular machine controlling T cell activation
-
Grakoui A, et al. The immunological synapse: a molecular machine controlling T cell activation. Science 1999;285:221-227.
-
(1999)
Science
, vol.285
, pp. 221-227
-
-
Grakoui, A.1
-
67
-
-
0036794399
-
Staging and resetting T cell activation in SMACs
-
Freiberg BA, et al. Staging and resetting T cell activation in SMACs. Nat Immunol 2002;3:911-917.
-
(2002)
Nat Immunol
, vol.3
, pp. 911-917
-
-
Freiberg, B.A.1
-
69
-
-
0036141994
-
Costimulation and endogenous MHC ligands contribute to T cell recognition
-
Wülfing C, Sumen C, Sjaastad MD, Wu LC, Dustin ML, Davis MM. Costimulation and endogenous MHC ligands contribute to T cell recognition. Nat Immunol 2002;3:42-47.
-
(2002)
Nat Immunol
, vol.3
, pp. 42-47
-
-
Wülfing, C.1
Sumen, C.2
Sjaastad, M.D.3
Wu, L.C.4
Dustin, M.L.5
Davis, M.M.6
-
70
-
-
0035826696
-
Cooperative enhancement of specificity in a lattice of T cell receptors
-
Chan C, George AJT, Stark J. Cooperative enhancement of specificity in a lattice of T cell receptors. Proc Natl Acad Sci USA 2001;98:5758-5763.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5758-5763
-
-
Chan, C.1
George, A.J.T.2
Stark, J.3
-
71
-
-
0036739732
-
Kinetic proofreading in receptor-mediated transduction of cellular signals: Receptor aggregation, partially activated receptors, and cytosolic messengers
-
Hlavacek WS, Redondo A, Wofsy C, Goldstein B. Kinetic proofreading in receptor-mediated transduction of cellular signals: receptor aggregation, partially activated receptors, and cytosolic messengers. Bull Math Biol 2002;64:887-911.
-
(2002)
Bull Math Biol
, vol.64
, pp. 887-911
-
-
Hlavacek, W.S.1
Redondo, A.2
Wofsy, C.3
Goldstein, B.4
-
72
-
-
2942588906
-
Mathematical and computational models of immune-receptor signalling
-
Goldstein B, Faeder JR, Hlavacek W. Mathematical and computational models of immune-receptor signalling. Nat Rev Immunol 2004;4:445-456.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 445-456
-
-
Goldstein, B.1
Faeder, J.R.2
Hlavacek, W.3
-
73
-
-
0029928254
-
A model for antigen-induced T cell unresponsiveness based on autophosphorylative protein tyrosine kinase activity
-
Kaufman M, Andris F, Leo O. A model for antigen-induced T cell unresponsiveness based on autophosphorylative protein tyrosine kinase activity. Int Immunol 1996;8:613-624.
-
(1996)
Int Immunol
, vol.8
, pp. 613-624
-
-
Kaufman, M.1
Andris, F.2
Leo, O.3
-
75
-
-
23044469067
-
Interaction between the CD8 coreceptor and MHC class I stabilizes TCR-antigen complexes at the cell surface
-
Wooldridge L, et al. Interaction between the CD8 coreceptor and MHC class I stabilizes TCR-antigen complexes at the cell surface. J Biol Chem 2005;280:27491-27501.
-
(2005)
J Biol Chem
, vol.280
, pp. 27491-27501
-
-
Wooldridge, L.1
-
76
-
-
0035914485
-
lck complexes
-
lck complexes. J Exp Med 2001;194:1485-1495.
-
(2001)
J Exp Med
, vol.194
, pp. 1485-1495
-
-
Arcaro, A.1
-
77
-
-
0036467498
-
Interactions between MHC molecules and coreceptors of the TCR
-
König R. Interactions between MHC molecules and coreceptors of the TCR. Curr Opin Immunol 2002;14:75-83.
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 75-83
-
-
König, R.1
-
78
-
-
0029807351
-
CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes
-
Garcia KC, Scott CA, Brunmark A, Carbone FR, Peterson PA, Teyton L. CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes. Nature 1996;384:577-581.
-
(1996)
Nature
, vol.384
, pp. 577-581
-
-
Garcia, K.C.1
Scott, C.A.2
Brunmark, A.3
Carbone, F.R.4
Peterson, P.A.5
Teyton, L.6
-
79
-
-
0028797801
-
CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes
-
Luescher IF, et al. CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes. Nature 1995;373:353-356.
-
(1995)
Nature
, vol.373
, pp. 353-356
-
-
Luescher, I.F.1
-
80
-
-
0029063148
-
Kinetic proofreading in T-cell receptor signal transduction
-
McKeithan TW. Kinetic proofreading in T-cell receptor signal transduction. Proc Natl Acad Sci USA 1995;92:5042-5046.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5042-5046
-
-
McKeithan, T.W.1
-
81
-
-
0029926145
-
Kinetic discrimination in T-cell activation
-
Rabinowitz JD, Beeson C, Lyons DS, Davis MM, McConnell HM. Kinetic discrimination in T-cell activation. Proc Natl Acad Sci USA 1996;93:1401- 1405.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1401-1405
-
-
Rabinowitz, J.D.1
Beeson, C.2
Lyons, D.S.3
Davis, M.M.4
McConnell, H.M.5
-
82
-
-
0030219704
-
Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity
-
Schodin BA, Tsomides TJ, Kranz DM. Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity. Immunity 1996;5:137-146.
-
(1996)
Immunity
, vol.5
, pp. 137-146
-
-
Schodin, B.A.1
Tsomides, T.J.2
Kranz, D.M.3
-
83
-
-
0033579882
-
The avidity spectrum of T cell receptor interactions accounts for T cell anergy in a double transgenic model
-
Girgis L, Davis MM, Fazekas de St. Groth B. The avidity spectrum of T cell receptor interactions accounts for T cell anergy in a double transgenic model. J Exp Med 1999;189:265-277.
-
(1999)
J Exp Med
, vol.189
, pp. 265-277
-
-
Girgis, L.1
Davis, M.M.2
Fazekas de, S.3
Groth, B.4
-
84
-
-
0042853581
-
T cell sensitivity and specificity - kinetic proofreading revisited
-
Chan C, George AFT, Stark J. T cell sensitivity and specificity - kinetic proofreading revisited. Discr Cont Dynam Sys B 2003;3:343-360.
-
Discr Cont Dynam Sys
, vol.B 2003
, Issue.3
, pp. 343-360
-
-
Chan, C.1
George, A.F.T.2
Stark, J.3
-
85
-
-
0031172162
-
Serial triggering of TCRs: A basis for the sensitivity and specificity of antigen recognition
-
Valitutti S, Lanzavecchia A. Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition. Immunol Today 1997;18:299-304.
-
(1997)
Immunol Today
, vol.18
, pp. 299-304
-
-
Valitutti, S.1
Lanzavecchia, A.2
-
86
-
-
16344370564
-
T-cell receptor binding kinetics required for T-cell activation depend on the density of the cognate ligand of the antigen-presenting cell
-
Gonzales PA, et al. T-cell receptor binding kinetics required for T-cell activation depend on the density of the cognate ligand of the antigen-presenting cell. Proc Natl Acad Sci USA 2005;102:4824-4829.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4824-4829
-
-
Gonzales, P.A.1
-
87
-
-
0033592574
-
A quantitative theory of affinity-driven T cell repertoire selection
-
Detours V, Mehr R, Perelson AS. A quantitative theory of affinity-driven T cell repertoire selection. J Theor Biol 1999;200:389-403.
-
(1999)
J Theor Biol
, vol.200
, pp. 389-403
-
-
Detours, V.1
Mehr, R.2
Perelson, A.S.3
-
88
-
-
2342502543
-
Dynamics of T cell activation threshold tuning
-
van den Berg HA, Rand DA. Dynamics of T cell activation threshold tuning. J Theor Biol 2004;228:397-416.
-
(2004)
J Theor Biol
, vol.228
, pp. 397-416
-
-
van den Berg, H.A.1
Rand, D.A.2
-
89
-
-
0026447431
-
The optimal number of major histocompatibility molecules in an individual
-
Nowak MA, Tarczy-Hornoch K, Austyn JM. The optimal number of major histocompatibility molecules in an individual. Proc Natl Acad Sci USA 1992;89:10896-10899.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10896-10899
-
-
Nowak, M.A.1
Tarczy-Hornoch, K.2
Austyn, J.M.3
-
90
-
-
0347405308
-
Thymic selection does not limit the individual MHC diversity
-
Borghans J, Noest A, de Boer RJ. Thymic selection does not limit the individual MHC diversity. Eur J Immunol 2003;33:3353-3358.
-
(2003)
Eur J Immunol
, vol.33
, pp. 3353-3358
-
-
Borghans, J.1
Noest, A.2
de Boer, R.J.3
-
91
-
-
0037373593
-
Quantitative constraints on the scope of negative selection
-
Müller V, Bonhoeffer S. Quantitative constraints on the scope of negative selection. Trends Immunol 2003;24:132-135.
-
(2003)
Trends Immunol
, vol.24
, pp. 132-135
-
-
Müller, V.1
Bonhoeffer, S.2
|