-
1
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
Monks C.R., Freiberg B.A., Kupfer H., Sciaky N., Kupfer A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 1998, 395:82-86.
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.R.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
2
-
-
0033538574
-
The immunological synapse: a molecular machine controlling T cell activation
-
Grakoui A., Bromley S.K., Sumen C., Davis M.M., Shaw A.S., Allen P.M., Dustin M.L. The immunological synapse: a molecular machine controlling T cell activation. Science 1999, 285:221-227.
-
(1999)
Science
, vol.285
, pp. 221-227
-
-
Grakoui, A.1
Bromley, S.K.2
Sumen, C.3
Davis, M.M.4
Shaw, A.S.5
Allen, P.M.6
Dustin, M.L.7
-
3
-
-
34247847666
-
T cells as a self-referential, sensory organ
-
Davis M.M., Krogsgaard M., Huse M., Huppa J., Lillemeier B.F., Li Q.J. T cells as a self-referential, sensory organ. Annu. Rev. Immunol. 2007, 25:681-695.
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 681-695
-
-
Davis, M.M.1
Krogsgaard, M.2
Huse, M.3
Huppa, J.4
Lillemeier, B.F.5
Li, Q.J.6
-
4
-
-
33845455093
-
Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes
-
Bajenoff M., Egen J.G., Koo L.Y., Laugier J.P., Brau F., Glaichenhaus N., Germain R.N. Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. Immunity 2006, 25:989-1001.
-
(2006)
Immunity
, vol.25
, pp. 989-1001
-
-
Bajenoff, M.1
Egen, J.G.2
Koo, L.Y.3
Laugier, J.P.4
Brau, F.5
Glaichenhaus, N.6
Germain, R.N.7
-
5
-
-
0028961573
-
Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton
-
Valitutti S., Dessing M., Aktories K., Gallati H., Lanzavecchia A. Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton. J. Exp. Med. 1995, 181:577-584.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 577-584
-
-
Valitutti, S.1
Dessing, M.2
Aktories, K.3
Gallati, H.4
Lanzavecchia, A.5
-
6
-
-
0005448458
-
Polarity of T cell shape, motility, and sensitivity to antigen
-
Negulescu P.A., Krasieva T.B., Khan A., Kerschbaum H.H., Cahalan M.D. Polarity of T cell shape, motility, and sensitivity to antigen. Immunity 1996, 4:421-430.
-
(1996)
Immunity
, vol.4
, pp. 421-430
-
-
Negulescu, P.A.1
Krasieva, T.B.2
Khan, A.3
Kerschbaum, H.H.4
Cahalan, M.D.5
-
7
-
-
0042931251
-
Regulation of sustained actin dynamics by the TCR and costimulation as a mechanism of receptor localization
-
Tskvitaria-Fuller I., Rozelle A.L., Yin H.L., Wulfing C. Regulation of sustained actin dynamics by the TCR and costimulation as a mechanism of receptor localization. J. Immunol. 2003, 171:2287-2295.
-
(2003)
J. Immunol.
, vol.171
, pp. 2287-2295
-
-
Tskvitaria-Fuller, I.1
Rozelle, A.L.2
Yin, H.L.3
Wulfing, C.4
-
8
-
-
64049108784
-
The cellular context of T cell signaling
-
Dustin M.L. The cellular context of T cell signaling. Immunity 2009, 30:482-492.
-
(2009)
Immunity
, vol.30
, pp. 482-492
-
-
Dustin, M.L.1
-
9
-
-
67349114397
-
T cell antigen receptor signaling and immunological synapse stability require myosin IIA
-
Ilani T., Vasiliver-Shamis G., Vardhana S., Bretscher A., Dustin M.L. T cell antigen receptor signaling and immunological synapse stability require myosin IIA. Nat. Immunol. 2009, 10:531-539.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 531-539
-
-
Ilani, T.1
Vasiliver-Shamis, G.2
Vardhana, S.3
Bretscher, A.4
Dustin, M.L.5
-
10
-
-
0036794399
-
Staging and resetting T cell activation in SMACs
-
Freiberg B.A., Kupfer H., Maslanik W., Delli J., Kappler J., Zaller D.M., Kupfer A. Staging and resetting T cell activation in SMACs. Nat. Immunol. 2002, 3:911-917.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 911-917
-
-
Freiberg, B.A.1
Kupfer, H.2
Maslanik, W.3
Delli, J.4
Kappler, J.5
Zaller, D.M.6
Kupfer, A.7
-
11
-
-
0035075507
-
Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT
-
Bunnell S.C., Kapoor V., Trible R.P., Zhang W., Samelson L.E. Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. Immunity 2001, 14:315-329.
-
(2001)
Immunity
, vol.14
, pp. 315-329
-
-
Bunnell, S.C.1
Kapoor, V.2
Trible, R.P.3
Zhang, W.4
Samelson, L.E.5
-
14
-
-
35648969165
-
Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses
-
Dustin M.L. Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses. Curr. Opin. Cell Biol. 2007, 19:529-533.
-
(2007)
Curr. Opin. Cell Biol.
, vol.19
, pp. 529-533
-
-
Dustin, M.L.1
-
15
-
-
39449094869
-
T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation
-
Henrickson S.E., et al. T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation. Nat. Immunol. 2008, 9:282-291.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 282-291
-
-
Henrickson, S.E.1
-
16
-
-
34547135943
-
Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes
-
Skokos D., et al. Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes. Nat. Immunol. 2007, 8:835-844.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 835-844
-
-
Skokos, D.1
-
17
-
-
77649255627
-
Subcellular dynamics of T cell immunological synapses and kinapses in lymph nodes
-
Azar G.A., Lemaitre F., Robey E.A., Bousso P. Subcellular dynamics of T cell immunological synapses and kinapses in lymph nodes. Proc. Natl. Acad. Sci. USA 2010, 107:3675-3680.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 3675-3680
-
-
Azar, G.A.1
Lemaitre, F.2
Robey, E.A.3
Bousso, P.4
-
18
-
-
51349131307
-
The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality
-
Cemerski S., Das J., Giurisato E., Markiewicz M.A., Allen P.M., Chakraborty A.K., Shaw A.S. The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality. Immunity 2008, 29:414-422.
-
(2008)
Immunity
, vol.29
, pp. 414-422
-
-
Cemerski, S.1
Das, J.2
Giurisato, E.3
Markiewicz, M.A.4
Allen, P.M.5
Chakraborty, A.K.6
Shaw, A.S.7
-
19
-
-
0242497659
-
The immunological synapse balances T cell receptor signaling and degradation
-
Lee K.H., et al. The immunological synapse balances T cell receptor signaling and degradation. Science 2003, 302:1218-1222.
-
(2003)
Science
, vol.302
, pp. 1218-1222
-
-
Lee, K.H.1
-
20
-
-
51549097744
-
Immunological synapse: center of attention again
-
Valitutti S. Immunological synapse: center of attention again. Immunity 2008, 29:384-386.
-
(2008)
Immunity
, vol.29
, pp. 384-386
-
-
Valitutti, S.1
-
21
-
-
30044441433
-
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76
-
Yokosuka T., Sakata-Sogawa K., Kobayashi W., Hiroshima M., Hashimoto-Tane A., Tokunaga M., Dustin M.L., Saito T. Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. Nat. Immunol. 2005, 6:1253-1262.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1253-1262
-
-
Yokosuka, T.1
Sakata-Sogawa, K.2
Kobayashi, W.3
Hiroshima, M.4
Hashimoto-Tane, A.5
Tokunaga, M.6
Dustin, M.L.7
Saito, T.8
-
22
-
-
27544441784
-
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
-
Campi G., Varma R., Dustin M.L. Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J. Exp. Med. 2005, 202:1031-1036.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1031-1036
-
-
Campi, G.1
Varma, R.2
Dustin, M.L.3
-
23
-
-
33746011209
-
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster
-
Varma R., Campi G., Yokosuka T., Saito T., Dustin M.L. T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster. Immunity 2006, 25:117-127.
-
(2006)
Immunity
, vol.25
, pp. 117-127
-
-
Varma, R.1
Campi, G.2
Yokosuka, T.3
Saito, T.4
Dustin, M.L.5
-
24
-
-
0028354216
-
Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions
-
Kupfer H., Monks C.R., Kupfer A. Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions. J. Exp. Med. 1994, 179:1507-1515.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1507-1515
-
-
Kupfer, H.1
Monks, C.R.2
Kupfer, A.3
-
25
-
-
0036166541
-
Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing
-
Kuhn J.R., Poenie M. Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing. Immunity 2002, 16:111-121.
-
(2002)
Immunity
, vol.16
, pp. 111-121
-
-
Kuhn, J.R.1
Poenie, M.2
-
26
-
-
78049386951
-
Activation of the ancestral polarity regulator protein kinase Czeta at the immunological synapse drives polarization of Th cell secretory machinery toward APCs
-
Bertrand F., Esquerre M., Petit A.E., Rodrigues M., Duchez S., Delon J., Valitutti S. Activation of the ancestral polarity regulator protein kinase Czeta at the immunological synapse drives polarization of Th cell secretory machinery toward APCs. J. Immunol. 2010, 185:2887-2894.
-
(2010)
J. Immunol.
, vol.185
, pp. 2887-2894
-
-
Bertrand, F.1
Esquerre, M.2
Petit, A.E.3
Rodrigues, M.4
Duchez, S.5
Delon, J.6
Valitutti, S.7
-
27
-
-
0035655587
-
The immunological synapse of CTL contains a secretory domain and membrane bridges
-
Stinchcombe J.C., Bossi G., Booth S., Griffiths G.M. The immunological synapse of CTL contains a secretory domain and membrane bridges. Immunity 2001, 15:751-761.
-
(2001)
Immunity
, vol.15
, pp. 751-761
-
-
Stinchcombe, J.C.1
Bossi, G.2
Booth, S.3
Griffiths, G.M.4
-
28
-
-
15744368010
-
T-cell activation is accompanied by an ubiquitination process occurring at the immunological synapse
-
Wiedemann A., Muller S., Favier B., Penna D., Guiraud M., Delmas C., Champagne E., Valitutti S. T-cell activation is accompanied by an ubiquitination process occurring at the immunological synapse. Immunol. Lett. 2005, 98:57-61.
-
(2005)
Immunol. Lett.
, vol.98
, pp. 57-61
-
-
Wiedemann, A.1
Muller, S.2
Favier, B.3
Penna, D.4
Guiraud, M.5
Delmas, C.6
Champagne, E.7
Valitutti, S.8
-
29
-
-
0345257150
-
Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: manifestation of a dual activation threshold
-
Faroudi M., Utzny C., Salio M., Cerundolo V., Guiraud M., Muller S., Valitutti S. Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: manifestation of a dual activation threshold. Proc. Natl. Acad. Sci. USA 2003, 100:14145-14150.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 14145-14150
-
-
Faroudi, M.1
Utzny, C.2
Salio, M.3
Cerundolo, V.4
Guiraud, M.5
Muller, S.6
Valitutti, S.7
-
30
-
-
2442651482
-
T cell killing does not require the formation of a stable mature immunological synapse
-
Purbhoo M.A., Irvine D.J., Huppa J.B., Davis M.M. T cell killing does not require the formation of a stable mature immunological synapse. Nat. Immunol. 2004, 5:524-530.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 524-530
-
-
Purbhoo, M.A.1
Irvine, D.J.2
Huppa, J.B.3
Davis, M.M.4
-
31
-
-
2442511061
-
Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse; involvement of SNARE complexes
-
Das V., Nal B., Dujeancourt A., Thoulouze M.I., Galli T., Roux P., Dautry-Varsat A., Alcover A. Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse; involvement of SNARE complexes. Immunity 2004, 20:577-588.
-
(2004)
Immunity
, vol.20
, pp. 577-588
-
-
Das, V.1
Nal, B.2
Dujeancourt, A.3
Thoulouze, M.I.4
Galli, T.5
Roux, P.6
Dautry-Varsat, A.7
Alcover, A.8
-
32
-
-
51649088000
-
MTOC translocation modulates IS formation and controls sustained T cell signaling
-
Martin-Cofreces N.B., et al. MTOC translocation modulates IS formation and controls sustained T cell signaling. J. Cell Biol. 2008, 182:951-962.
-
(2008)
J. Cell Biol.
, vol.182
, pp. 951-962
-
-
Martin-Cofreces, N.B.1
-
33
-
-
70449517408
-
Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse
-
Finetti F., Paccani S.R., Riparbelli M.G., Giacomello E., Perinetti G., Pazour G.J., Rosenbaum J.L., Baldari C.T. Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse. Nat. Cell Biol. 2009, 11:1332-1339.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1332-1339
-
-
Finetti, F.1
Paccani, S.R.2
Riparbelli, M.G.3
Giacomello, E.4
Perinetti, G.5
Pazour, G.J.6
Rosenbaum, J.L.7
Baldari, C.T.8
-
34
-
-
0036798653
-
In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern
-
Blanchard N., Di Bartolo V., Hivroz C. In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern. Immunity 2002, 17:389-399.
-
(2002)
Immunity
, vol.17
, pp. 389-399
-
-
Blanchard, N.1
Di Bartolo, V.2
Hivroz, C.3
-
35
-
-
70249114140
-
The polarity protein Par1b/EMK/MARK2 regulates T cell receptor-induced microtubule-organizing center polarization
-
Lin J., Hou K.K., Piwnica-Worms H., Shaw A.S. The polarity protein Par1b/EMK/MARK2 regulates T cell receptor-induced microtubule-organizing center polarization. J. Immunol. 2009, 183:1215-1221.
-
(2009)
J. Immunol.
, vol.183
, pp. 1215-1221
-
-
Lin, J.1
Hou, K.K.2
Piwnica-Worms, H.3
Shaw, A.S.4
-
36
-
-
0025286210
-
Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation
-
Harding C.V., Unanue E.R. Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation. Nature 1990, 346:574-576.
-
(1990)
Nature
, vol.346
, pp. 574-576
-
-
Harding, C.V.1
Unanue, E.R.2
-
37
-
-
0025182003
-
The minimal number of class II MHC-antigen complexes needed for T cell activation
-
Demotz S., Grey H.M., Sette A. The minimal number of class II MHC-antigen complexes needed for T cell activation. Science 1990, 249:1028-1030.
-
(1990)
Science
, vol.249
, pp. 1028-1030
-
-
Demotz, S.1
Grey, H.M.2
Sette, A.3
-
38
-
-
0032547759
-
Antigen-dependent and -independent Ca2+ responses triggered in T cells by dendritic cells compared with B cells
-
Delon J., Bercovici N., Raposo G., Liblau R., Trautmann A. Antigen-dependent and -independent Ca2+ responses triggered in T cells by dendritic cells compared with B cells. J. Exp. Med. 1998, 188:1473-1484.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1473-1484
-
-
Delon, J.1
Bercovici, N.2
Raposo, G.3
Liblau, R.4
Trautmann, A.5
-
39
-
-
0030176270
-
Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response
-
Sykulev Y., Joo M., Vturina I., Tsomides T.J., Eisen H.N. Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response. Immunity 1996, 4:565-571.
-
(1996)
Immunity
, vol.4
, pp. 565-571
-
-
Sykulev, Y.1
Joo, M.2
Vturina, I.3
Tsomides, T.J.4
Eisen, H.N.5
-
40
-
-
0037167816
-
Direct observation of ligand recognition by T cells
-
Irvine D.J., Purbhoo M.A., Krogsgaard M., Davis M.M. Direct observation of ligand recognition by T cells. Nature 2002, 419:845-849.
-
(2002)
Nature
, vol.419
, pp. 845-849
-
-
Irvine, D.J.1
Purbhoo, M.A.2
Krogsgaard, M.3
Davis, M.M.4
-
41
-
-
0026606454
-
Imaging early steps of human T cell activation by antigen-presenting cells
-
Donnadieu E., Cefai D., Tan Y.P., Paresys G., Bismuth G., Trautmann A. Imaging early steps of human T cell activation by antigen-presenting cells. J. Immunol. 1992, 148:2643-2653.
-
(1992)
J. Immunol.
, vol.148
, pp. 2643-2653
-
-
Donnadieu, E.1
Cefai, D.2
Tan, Y.P.3
Paresys, G.4
Bismuth, G.5
Trautmann, A.6
-
42
-
-
0036852243
-
Imaging antigen-induced PI3K activation in T cells
-
Harriague J., Bismuth G. Imaging antigen-induced PI3K activation in T cells. Nat. Immunol. 2002, 3:1090-1096.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1090-1096
-
-
Harriague, J.1
Bismuth, G.2
-
43
-
-
0036853106
-
Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse
-
Costello P.S., Gallagher M., Cantrell D.A. Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse. Nat. Immunol. 2002, 3:1082-1089.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1082-1089
-
-
Costello, P.S.1
Gallagher, M.2
Cantrell, D.A.3
-
44
-
-
0023156442
-
Ligand-receptor interactions required for commitment to the activation of the interleukin 2 gene
-
Weiss A., Shields R., Newton M., Manger B., Imboden J. Ligand-receptor interactions required for commitment to the activation of the interleukin 2 gene. J. Immunol. 1987, 138:2169-2176.
-
(1987)
J. Immunol.
, vol.138
, pp. 2169-2176
-
-
Weiss, A.1
Shields, R.2
Newton, M.3
Manger, B.4
Imboden, J.5
-
45
-
-
0031884839
-
The duration of antigenic stimulation determines the fate of naive and effector T cells
-
Iezzi G., Karjalainen K., Lanzavecchia A. The duration of antigenic stimulation determines the fate of naive and effector T cells. Immunity 1998, 8:89-95.
-
(1998)
Immunity
, vol.8
, pp. 89-95
-
-
Iezzi, G.1
Karjalainen, K.2
Lanzavecchia, A.3
-
46
-
-
0037120052
-
The proliferative capacity of individual naive CD4(+) T cells is amplified by prolonged T cell antigen receptor triggering
-
Schrum A.G., Turka L.A. The proliferative capacity of individual naive CD4(+) T cells is amplified by prolonged T cell antigen receptor triggering. J. Exp. Med. 2002, 196:793-803.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 793-803
-
-
Schrum, A.G.1
Turka, L.A.2
-
47
-
-
0029851762
-
Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression
-
Timmerman L.A., Clipstone N.A., Ho S.N., Northrop J.P., Crabtree G.R. Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression. Nature 1996, 383:837-840.
-
(1996)
Nature
, vol.383
, pp. 837-840
-
-
Timmerman, L.A.1
Clipstone, N.A.2
Ho, S.N.3
Northrop, J.P.4
Crabtree, G.R.5
-
48
-
-
15444369929
-
Stable activation of phosphatidylinositol 3-kinase in the T cell immunological synapse stimulates Akt signaling to FoxO1 nuclear exclusion and cell growth control
-
Fabre S., Lang V., Harriague J., Jobart A., Unterman T.G., Trautmann A., Bismuth G. Stable activation of phosphatidylinositol 3-kinase in the T cell immunological synapse stimulates Akt signaling to FoxO1 nuclear exclusion and cell growth control. J. Immunol. 2005, 174:4161-4171.
-
(2005)
J. Immunol.
, vol.174
, pp. 4161-4171
-
-
Fabre, S.1
Lang, V.2
Harriague, J.3
Jobart, A.4
Unterman, T.G.5
Trautmann, A.6
Bismuth, G.7
-
49
-
-
0032580202
-
Calcium oscillations increase the efficiency and specificity of gene expression
-
Dolmetsch R.E., Xu K., Lewis R.S. Calcium oscillations increase the efficiency and specificity of gene expression. Nature 1998, 392:933-936.
-
(1998)
Nature
, vol.392
, pp. 933-936
-
-
Dolmetsch, R.E.1
Xu, K.2
Lewis, R.S.3
-
50
-
-
11244256431
-
Frequency encoding of T-cell receptor engagement dynamics in calcium time series
-
Utzny C., Faroudi M., Valitutti S. Frequency encoding of T-cell receptor engagement dynamics in calcium time series. Biophys. J. 2005, 88:1-14.
-
(2005)
Biophys. J.
, vol.88
, pp. 1-14
-
-
Utzny, C.1
Faroudi, M.2
Valitutti, S.3
-
51
-
-
0029063148
-
Kinetic proofreading in T-cell receptor signal transduction
-
McKeithan T.W. Kinetic proofreading in T-cell receptor signal transduction. Proc. Natl. Acad. Sci. USA 1995, 92:5042-5046.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5042-5046
-
-
McKeithan, T.W.1
-
52
-
-
85012563943
-
T-cell receptor binding kinetics in T-cell development and activation
-
Gascoigne N.R., Zal T., Alam S.M. T-cell receptor binding kinetics in T-cell development and activation. Expert Rev. Mol. Med. 2001, 2001:1-17.
-
(2001)
Expert Rev. Mol. Med.
, vol.2001
, pp. 1-17
-
-
Gascoigne, N.R.1
Zal, T.2
Alam, S.M.3
-
53
-
-
0029037210
-
Serial triggering of many T-cell receptors by a few peptide-MHC complexes
-
Valitutti S., Muller S., Cella M., Padovan E., Lanzavecchia A. Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature 1995, 375:148-151.
-
(1995)
Nature
, vol.375
, pp. 148-151
-
-
Valitutti, S.1
Muller, S.2
Cella, M.3
Padovan, E.4
Lanzavecchia, A.5
-
54
-
-
0031571327
-
Peptide antigen or superantigen-induced down-regulation of TCRs involves both stimulated and unstimulated receptors
-
Niedergang F., Dautry-Varsat A., Alcover A. Peptide antigen or superantigen-induced down-regulation of TCRs involves both stimulated and unstimulated receptors. J. Immunol. 1997, 159:1703-1710.
-
(1997)
J. Immunol.
, vol.159
, pp. 1703-1710
-
-
Niedergang, F.1
Dautry-Varsat, A.2
Alcover, A.3
-
55
-
-
0034288890
-
Triggering the TCR complex causes the downregulation of nonengaged receptors by a signal transduction-dependent mechanism
-
San Jose E., Borroto A., Niedergang F., Alcover A., Alarcon B. Triggering the TCR complex causes the downregulation of nonengaged receptors by a signal transduction-dependent mechanism. Immunity 2000, 12:161-170.
-
(2000)
Immunity
, vol.12
, pp. 161-170
-
-
San Jose, E.1
Borroto, A.2
Niedergang, F.3
Alcover, A.4
Alarcon, B.5
-
56
-
-
0042834315
-
TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism
-
Bonefeld C.M., Rasmussen A.B., Lauritsen J.P., von Essen M., Odum N., Andersen P.S., Geisler C. TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism. J. Immunol. 2003, 171:3003-3009.
-
(2003)
J. Immunol.
, vol.171
, pp. 3003-3009
-
-
Bonefeld, C.M.1
Rasmussen, A.B.2
Lauritsen, J.P.3
von Essen, M.4
Odum, N.5
Andersen, P.S.6
Geisler, C.7
-
57
-
-
3442882817
-
Dual T cell receptor T cells with two defined specificities mediate tumor suppression via both receptors
-
Gladow M., Uckert W., Blankenstein T. Dual T cell receptor T cells with two defined specificities mediate tumor suppression via both receptors. Eur. J. Immunol. 2004, 34:1882-1891.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 1882-1891
-
-
Gladow, M.1
Uckert, W.2
Blankenstein, T.3
-
58
-
-
33749256646
-
Analysis of peptide/MHC-induced TCR downregulation: deciphering the triggering kinetics
-
Utzny C., Coombs D., Muller S., Valitutti S. Analysis of peptide/MHC-induced TCR downregulation: deciphering the triggering kinetics. Cell Biochem. Biophys. 2006, 46:101-111.
-
(2006)
Cell Biochem. Biophys.
, vol.46
, pp. 101-111
-
-
Utzny, C.1
Coombs, D.2
Muller, S.3
Valitutti, S.4
-
59
-
-
0035146577
-
Calculations show substantial serial engagement of T cell receptors
-
Wofsy C., Coombs D., Goldstein B. Calculations show substantial serial engagement of T cell receptors. Biophys. J. 2001, 80:606-612.
-
(2001)
Biophys. J.
, vol.80
, pp. 606-612
-
-
Wofsy, C.1
Coombs, D.2
Goldstein, B.3
-
60
-
-
0036795530
-
Activated TCRs remain marked for internalization after dissociation from pMHC
-
Coombs D., Kalergis A.M., Nathenson S.G., Wofsy C., Goldstein B. Activated TCRs remain marked for internalization after dissociation from pMHC. Nat. Immunol. 2002, 3:926-931.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 926-931
-
-
Coombs, D.1
Kalergis, A.M.2
Nathenson, S.G.3
Wofsy, C.4
Goldstein, B.5
-
61
-
-
0032528403
-
The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement
-
Hudrisier D., Kessler B., Valitutti S., Horvath C., Cerottini J.C., Luescher I.F. The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement. J. Immunol. 1998, 161:553-562.
-
(1998)
J. Immunol.
, vol.161
, pp. 553-562
-
-
Hudrisier, D.1
Kessler, B.2
Valitutti, S.3
Horvath, C.4
Cerottini, J.C.5
Luescher, I.F.6
-
62
-
-
0035286588
-
Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex
-
Kalergis A.M., Boucheron N., Doucey M.A., Palmieri E., Goyarts E.C., Vegh Z., Luescher I.F., Nathenson S.G. Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex. Nat. Immunol. 2001, 2:229-234.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 229-234
-
-
Kalergis, A.M.1
Boucheron, N.2
Doucey, M.A.3
Palmieri, E.4
Goyarts, E.C.5
Vegh, Z.6
Luescher, I.F.7
Nathenson, S.G.8
-
63
-
-
33947189706
-
The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse
-
Cemerski S., et al. The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse. Immunity 2007, 26:345-355.
-
(2007)
Immunity
, vol.26
, pp. 345-355
-
-
Cemerski, S.1
-
64
-
-
0035887216
-
CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation
-
Holler P.D., Lim A.R., Cho B.K., Rund L.A., Kranz D.M. CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation. J. Exp. Med. 2001, 194:1043-1052.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1043-1052
-
-
Holler, P.D.1
Lim, A.R.2
Cho, B.K.3
Rund, L.A.4
Kranz, D.M.5
-
65
-
-
38449086723
-
CD8+ T cell activation is governed by TCR-peptide/MHC Affinity, not dissociation rate
-
Tian S., Maile R., Collins E.J., Frelinger J.A. CD8+ T cell activation is governed by TCR-peptide/MHC Affinity, not dissociation rate. J. Immunol. 2007, 179:2952-2960.
-
(2007)
J. Immunol.
, vol.179
, pp. 2952-2960
-
-
Tian, S.1
Maile, R.2
Collins, E.J.3
Frelinger, J.A.4
-
66
-
-
76949085272
-
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time
-
Aleksic M., Dushek O., Zhang H., Shenderov E., Chen J.L., Cerundolo V., Coombs D., van der Merwe P.A. Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time. Immunity 2010, 32:163-174.
-
(2010)
Immunity
, vol.32
, pp. 163-174
-
-
Aleksic, M.1
Dushek, O.2
Zhang, H.3
Shenderov, E.4
Chen, J.L.5
Cerundolo, V.6
Coombs, D.7
van der Merwe, P.A.8
-
67
-
-
77952712883
-
Fast on-rates allow short dwell time ligands to activate T cells
-
Govern C.C., Paczosa M.K., Chakraborty A.K., Huseby E.S. Fast on-rates allow short dwell time ligands to activate T cells. Proc. Natl. Acad. Sci. USA 2010, 107:8724-8729.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 8724-8729
-
-
Govern, C.C.1
Paczosa, M.K.2
Chakraborty, A.K.3
Huseby, E.S.4
-
68
-
-
73449105773
-
A role for rebinding in rapid and reliable T cell responses to antigen
-
Dushek O., Das R., Coombs D. A role for rebinding in rapid and reliable T cell responses to antigen. PLoS Comput. Biol. 2009, 5:e1000578.
-
(2009)
PLoS Comput. Biol.
, vol.5
-
-
Dushek, O.1
Das, R.2
Coombs, D.3
-
69
-
-
0037331525
-
Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation
-
Holler P.D., Kranz D.M. Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation. Immunity 2003, 18:255-264.
-
(2003)
Immunity
, vol.18
, pp. 255-264
-
-
Holler, P.D.1
Kranz, D.M.2
-
70
-
-
34548264739
-
Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties
-
Laugel B., et al. Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties. J. Biol. Chem. 2007, 282:23799-23810.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 23799-23810
-
-
Laugel, B.1
-
71
-
-
4444298148
-
CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse
-
Li Q.J., Dinner A.R., Qi S., Irvine D.J., Huppa J.B., Davis M.M., Chakraborty A.K. CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse. Nat. Immunol. 2004, 5:791-799.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 791-799
-
-
Li, Q.J.1
Dinner, A.R.2
Qi, S.3
Irvine, D.J.4
Huppa, J.B.5
Davis, M.M.6
Chakraborty, A.K.7
-
72
-
-
77249114784
-
TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity
-
Huppa J.B., et al. TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity. Nature 2010, 463:963-967.
-
(2010)
Nature
, vol.463
, pp. 963-967
-
-
Huppa, J.B.1
-
73
-
-
0028797801
-
CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes
-
Luescher I.F., Vivier E., Layer A., Mahiou J., Godeau F., Malissen B., Romero P. CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes. Nature 1995, 373:353-356.
-
(1995)
Nature
, vol.373
, pp. 353-356
-
-
Luescher, I.F.1
Vivier, E.2
Layer, A.3
Mahiou, J.4
Godeau, F.5
Malissen, B.6
Romero, P.7
-
74
-
-
78049266750
-
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery
-
Artyomov M.N., Lis M., Devadas S., Davis M.M., Chakraborty A.K. CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery. Proc. Natl. Acad. Sci. USA 2010, 107:16916-16921.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 16916-16921
-
-
Artyomov, M.N.1
Lis, M.2
Devadas, S.3
Davis, M.M.4
Chakraborty, A.K.5
-
75
-
-
77950809538
-
The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness
-
Huang J., Zarnitsyna V.I., Liu B., Edwards L.J., Jiang N., Evavold B.D., Zhu C. The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness. Nature 2010, 464:932-936.
-
(2010)
Nature
, vol.464
, pp. 932-936
-
-
Huang, J.1
Zarnitsyna, V.I.2
Liu, B.3
Edwards, L.J.4
Jiang, N.5
Evavold, B.D.6
Zhu, C.7
-
76
-
-
33748809527
-
T cell receptor recognition via cooperative conformational plasticity
-
Gagnon S.J., Borbulevych O.Y., Davis-Harrison R.L., Turner R.V., Damirjian M., Wojnarowicz A., Biddison W.E., Baker B.M. T cell receptor recognition via cooperative conformational plasticity. J. Mol. Biol. 2006, 363:228-243.
-
(2006)
J. Mol. Biol.
, vol.363
, pp. 228-243
-
-
Gagnon, S.J.1
Borbulevych, O.Y.2
Davis-Harrison, R.L.3
Turner, R.V.4
Damirjian, M.5
Wojnarowicz, A.6
Biddison, W.E.7
Baker, B.M.8
-
77
-
-
31144479383
-
CD8 T cells, like CD4 T cells, are triggered by multivalent engagement of TCRs by MHC-peptide ligands but not by monovalent engagement
-
Stone J.D., Stern L.J. CD8 T cells, like CD4 T cells, are triggered by multivalent engagement of TCRs by MHC-peptide ligands but not by monovalent engagement. J. Immunol. 2006, 176:1498-1505.
-
(2006)
J. Immunol.
, vol.176
, pp. 1498-1505
-
-
Stone, J.D.1
Stern, L.J.2
-
78
-
-
0032192469
-
Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]
-
Boniface J.J., et al. Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]. Immunity 1998, 9:459-466.
-
(1998)
Immunity
, vol.9
, pp. 459-466
-
-
Boniface, J.J.1
-
79
-
-
0033666324
-
Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential
-
Gunzer M., Schafer A., Borgmann S., Grabbe S., Zanker K.S., Brocker E.B., Kampgen E., Friedl P. Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential. Immunity 2000, 13:323-332.
-
(2000)
Immunity
, vol.13
, pp. 323-332
-
-
Gunzer, M.1
Schafer, A.2
Borgmann, S.3
Grabbe, S.4
Zanker, K.S.5
Brocker, E.B.6
Kampgen, E.7
Friedl, P.8
-
80
-
-
0042847271
-
Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling
-
Faroudi M., Zaru R., Paulet P., Muller S., Valitutti S. Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling. J. Immunol. 2003, 171:1128-1132.
-
(2003)
J. Immunol.
, vol.171
, pp. 1128-1132
-
-
Faroudi, M.1
Zaru, R.2
Paulet, P.3
Muller, S.4
Valitutti, S.5
-
81
-
-
0038491287
-
Restricted clonal expression of IL-2 by naive T cells reflects differential dynamic interactions with dendritic cells
-
Hurez V., Saparov A., Tousson A., Fuller M.J., Kubo T., Oliver J., Weaver B.T., Weaver C.T. Restricted clonal expression of IL-2 by naive T cells reflects differential dynamic interactions with dendritic cells. J. Exp. Med. 2003, 198:123-132.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 123-132
-
-
Hurez, V.1
Saparov, A.2
Tousson, A.3
Fuller, M.J.4
Kubo, T.5
Oliver, J.6
Weaver, B.T.7
Weaver, C.T.8
|