메뉴 건너뛰기




Volumn 19, Issue 25, 2012, Pages 4247-4258

Insights into targeting colon cancer cell fate at the level of proteoglycans / glycosaminoglycans

Author keywords

Chondroitin sulfate; Colorectal cancer; Glycosaminoglycans; Heparan sulfate; Hyaluronan; Metastasis; Proteoglycans; Therapeutic targets; Tumor cell signaling

Indexed keywords

CD44V ANTIGEN; CHONDROITIN; DERMATAN SULFATE; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HERMES ANTIGEN; HYALURONIC ACID; PROTEOGLYCAN; RECEPTOR; RECEPTOR FOR HYALURONAN MEDIATED MOTILITY; UNCLASSIFIED DRUG;

EID: 84866673728     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712802884268     Document Type: Article
Times cited : (28)

References (167)
  • 1
    • 79957749035 scopus 로고    scopus 로고
    • The intestinal epithelial barrier in the control of homeostasis and immunity
    • Rescigno, M. The intestinal epithelial barrier in the control of homeostasis and immunity. Trends Immunol., 2011, 32, 256-264
    • (2011) Trends Immunol. , vol.32 , pp. 256-264
    • Rescigno, M.1
  • 2
    • 79955799724 scopus 로고    scopus 로고
    • Wound healing of intestinal epithelial cells
    • Iizuka, M.; Konno, S. Wound healing of intestinal epithelial cells. World J. Gastroenterol., 2011, 17, 2161-2171
    • (2011) World J. Gastroenterol. , vol.17 , pp. 2161-2171
    • Iizuka, M.1    Konno, S.2
  • 3
    • 77955504104 scopus 로고    scopus 로고
    • Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesis
    • Li, P.; Waldman, S.A. Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesis. Cancer Biol. Ther., 2010, 10, 211-218
    • (2010) Cancer Biol. Ther. , vol.10 , pp. 211-218
    • Li, P.1    Waldman, S.A.2
  • 4
    • 79959544806 scopus 로고    scopus 로고
    • Molecular regulation of the intestinal epithelial barrier: Implication in human diseases
    • Liu, Z.; Shi, C.; Yang, J.; Zhang, P.; Ma, Y.; Wang, F.; Qin, H. Molecular regulation of the intestinal epithelial barrier: implication in human diseases. Front. Biosci., 2011, 17, 2903-2909
    • (2011) Front. Biosci. , vol.17 , pp. 2903-2909
    • Liu, Z.1    Shi, C.2    Yang, J.3    Zhang, P.4    Ma, Y.5    Wang, F.6    Qin, H.7
  • 6
    • 1242292420 scopus 로고    scopus 로고
    • Genomic instability and colon cancer
    • Grady, W.M. Genomic instability and colon cancer. Cancer Metastasis Rev., 2004, 23, 11-27
    • (2004) Cancer Metastasis Rev. , vol.23 , pp. 11-27
    • Grady, W.M.1
  • 7
    • 36649020481 scopus 로고    scopus 로고
    • Inherited multitumoral syndromes including colorectal carcinoma
    • Cetta, F.; Dhamo, D. Inherited multitumoral syndromes including colorectal carcinoma. Surg. Oncol., 2007, 16, S17-23
    • (2007) Surg. Oncol. , vol.16
    • Cetta, F.1    Dhamo, D.2
  • 8
    • 34249690154 scopus 로고    scopus 로고
    • Microarray analysis to reveal genes involved in colon carcinogenesis
    • Joyce, T.; Pintzas, A. Microarray analysis to reveal genes involved in colon carcinogenesis. Expert Opin. Pharmacother, 2007, 8, 895-900
    • (2007) Expert Opin. Pharmacother , vol.8 , pp. 895-900
    • Joyce, T.1    Pintzas, A.2
  • 9
    • 0027023012 scopus 로고
    • Suppressor gene alterations in the colorectal adenoma-carcinoma sequence
    • Cho, K.R.; Vogelstein, B. Suppressor gene alterations in the colorectal adenoma-carcinoma sequence. J. Cell Biochem., 1992, 16, 137-141
    • (1992) J. Cell Biochem. , vol.16 , pp. 137-141
    • Cho, K.R.1    Vogelstein, B.2
  • 10
    • 13844311204 scopus 로고    scopus 로고
    • Environmental and other risk factors for colorectal carcinogenesis
    • Papapolychroniadis, C. Environmental and other risk factors for colorectal carcinogenesis. Tech. Coloproctol., 2004, 8, 7-9
    • (2004) Tech. Coloproctol. , vol.8 , pp. 7-9
    • Papapolychroniadis, C.1
  • 12
    • 35348930394 scopus 로고    scopus 로고
    • Long-term use of progestogens: Colon adenoma and colon carcinoma
    • Schindler, A.E. Long-term use of progestogens: colon adenoma and colon carcinoma. Gynecol. Endocrinol., 2007, 23, 42-44
    • (2007) Gynecol. Endocrinol. , vol.23 , pp. 42-44
    • Schindler, A.E.1
  • 14
    • 0036113238 scopus 로고    scopus 로고
    • Tumor-associated fibroblasts (part I): Active stromal participants in tumor development and progression?
    • 2002
    • Kunz-Schughart, L.A.; Knuechel, R. (2002) Tumor-associated fibroblasts (part I): active stromal participants in tumor development and progression? Histol Histopathol., 2002, 17, 599-621
    • (2002) Histol Histopathol. , vol.17 , pp. 599-621
    • Kunz-Schughart, L.A.1    Knuechel, R.2
  • 15
    • 0036329807 scopus 로고    scopus 로고
    • New insights into the role of extracellular matrix during tumor onset and progression
    • Pupa, S.M.; Menard, S.; Forti, S.; Tagliabue, E. New insights into the role of extracellular matrix during tumor onset and progression. J. Cell Physiol., 2002, 192, 259-267
    • (2002) J. Cell Physiol. , vol.192 , pp. 259-267
    • Pupa, S.M.1    Menard, S.2    Forti, S.3    Tagliabue, E.4
  • 16
    • 15244348665 scopus 로고    scopus 로고
    • Tumor-stroma interactions: Their role in the control of tumor cell invasion
    • Zigrino, P.; Loffek, S.; Mauch, C. Tumor-stroma interactions: their role in the control of tumor cell invasion. Biochimie, 2005, 87, 321-328
    • (2005) Biochimie , vol.87 , pp. 321-328
    • Zigrino, P.1    Loffek, S.2    Mauch, C.3
  • 17
    • 8444250723 scopus 로고    scopus 로고
    • Tumour-stroma interaction: Cancer-associated fibroblasts as novel targets in anti-cancer therapy
    • Micke, P.; Ostman, A. Tumour-stroma interaction: cancer-associated fibroblasts as novel targets in anti-cancer therapy. Lung Cancer, 2004, 45 (Suppl 2), S163-175
    • (2004) Lung Cancer , vol.45 , Issue.SUPPL. 2
    • Micke, P.1    Ostman, A.2
  • 18
    • 0032842777 scopus 로고    scopus 로고
    • Extracellular matrix remodelling and cellular differentiation
    • Streuli, C. Extracellular matrix remodelling and cellular differentiation. Curr Opin. Cell Biol., 1999, 11, 634-640
    • (1999) Curr Opin. Cell Biol. , vol.11 , pp. 634-640
    • Streuli, C.1
  • 19
    • 33745928751 scopus 로고    scopus 로고
    • Management of advanced colorectal cancer: State of the art
    • Saunders, M.; Iveson, T. Management of advanced colorectal cancer: state of the art. Br. J Cancer, 2006, 95, 131-138.
    • (2006) Br. J Cancer , vol.95 , pp. 131-138
    • Saunders, M.1    Iveson, T.2
  • 20
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • Siegel, R.; Ward, E.; Brawley, O.; Jemal, A. Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin., 2011, 61, 212-236
    • (2011) CA Cancer J Clin. , vol.61 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawley, O.3    Jemal, A.4
  • 21
    • 84859949610 scopus 로고    scopus 로고
    • The extracellular matrix: A dynamic niche in cancer progression
    • Lu, P.; Weaver, V.M.; Werb, Z. The extracellular matrix: a dynamic niche in cancer progression. J. Cell Biol. 2012, 196, 395-406
    • (2012) J. Cell Biol. , vol.196 , pp. 395-406
    • Lu, P.1    Weaver, V.M.2    Werb, Z.3
  • 22
    • 77956637386 scopus 로고    scopus 로고
    • Proteoglycans in health and disease: Emerging concepts and future directions
    • Iozzo, R.V.; Karamanos, N.K. Proteoglycans in health and disease: emerging concepts and future directions. FEBS J., 2010, 277, 3863
    • (2010) FEBS J , vol.277 , pp. 3863
    • Iozzo, R.V.1    Karamanos, N.K.2
  • 23
    • 77956641177 scopus 로고    scopus 로고
    • Proteoglycans in health and disease: Novel roles for proteoglycans in malignancy and their pharmacological targeting
    • Theocharis, A.D.; Skandalis, S.S.; Tzanakakis, G.N.; Karamanos, N.K. Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting. FEBS J, 2010, 277, 3904-3923
    • (2010) FEBS J , vol.277 , pp. 3904-3923
    • Theocharis, A.D.1    Skandalis, S.S.2    Tzanakakis, G.N.3    Karamanos, N.K.4
  • 24
    • 84859102378 scopus 로고    scopus 로고
    • Glycosaminoglycans: From "cellular glue" to novel therapeutical agents
    • Feb 9. [Epub ahead of print]
    • Karamanos, N.K.; Tzanakakis, G.N. Glycosaminoglycans: from "cellular glue" to novel therapeutical agents. Curr. Opin. Pharmacol., 2012, Feb 9. [Epub ahead of print]
    • (2012) Curr. Opin. Pharmacol.
    • Karamanos, N.K.1    Tzanakakis, G.N.2
  • 26
    • 0035988813 scopus 로고    scopus 로고
    • Matrix-directed regulation of pericellular proteolysis and tumor progression
    • Hornebeck, W.; Emonard, H.; Monboisse, J.C.; Bellon, G. Matrix-directed regulation of pericellular proteolysis and tumor progression. Semin Cancer Biol., 2002, 12, 231-241
    • (2002) Semin Cancer Biol. , vol.12 , pp. 231-241
    • Hornebeck, W.1    Emonard, H.2    Monboisse, J.C.3    Bellon, G.4
  • 27
    • 0032855574 scopus 로고    scopus 로고
    • Effects of glycosaminoglycans on proliferation of epithelial and fibroblast human malignant mesothelioma cells: A structure-function relationship
    • Syrokou, A.; Tzanakakis, G.; Tsegenidis, T.; Hjerpe, A.; Karamanos, N.K. Effects of glycosaminoglycans on proliferation of epithelial and fibroblast human malignant mesothelioma cells: a structure-function relationship. Cell Prolif., 1999, 32, 85-99
    • (1999) Cell Prolif. , vol.32 , pp. 85-99
    • Syrokou, A.1    Tzanakakis, G.2    Tsegenidis, T.3    Hjerpe, A.4    Karamanos, N.K.5
  • 28
    • 22944470086 scopus 로고    scopus 로고
    • Effects of glycosaminoglycans on cell proliferation of normal osteoblasts and human osteosarcoma cells depend on their type and fine chemical compositions
    • Nikitovic, D.; Zafiropoulos, A.; Tzanakakis, G.N.; Karamanos, N.K.; Tsatsakis, A.M. Effects of glycosaminoglycans on cell proliferation of normal osteoblasts and human osteosarcoma cells depend on their type and fine chemical compositions. Anticancer Res., 2005, 25, 2851-2856
    • (2005) Anticancer Res. , vol.25 , pp. 2851-2856
    • Nikitovic, D.1    Zafiropoulos, A.2    Tzanakakis, G.N.3    Karamanos, N.K.4    Tsatsakis, A.M.5
  • 29
    • 0036990102 scopus 로고    scopus 로고
    • Tumor-stroma interactions directing phenotype and progression of epithelial skin tumor cells
    • Mueller, M.M.; Fusenig, N.E. Tumor-stroma interactions directing phenotype and progression of epithelial skin tumor cells. Differentiation, 2002, 70, 486-497
    • (2002) Differentiation , vol.70 , pp. 486-497
    • Mueller, M.M.1    Fusenig, N.E.2
  • 30
    • 0036765669 scopus 로고    scopus 로고
    • In vitro effects of genistein on the synthesis and distribution of glycosaminoglycans/proteoglycans by estrogen receptorpositive and -negative human breast cancer epithelial cells
    • Mitropoulou, T.N.; Tzanakakis, G.N.; Nikitovic, D.; Tsatsakis, A.; Karamanos, N.K. In vitro effects of genistein on the synthesis and distribution of glycosaminoglycans/proteoglycans by estrogen receptorpositive and -negative human breast cancer epithelial cells. Anticancer Res., 2002, 22, 2841-2846
    • (2002) Anticancer Res. , vol.22 , pp. 2841-2846
    • Mitropoulou, T.N.1    Tzanakakis, G.N.2    Nikitovic, D.3    Tsatsakis, A.4    Karamanos, N.K.5
  • 31
    • 37549021042 scopus 로고    scopus 로고
    • Protein tyrosine kinase and estrogen receptor-dependent pathways regulate the synthesis and distribution of glycosaminoglycans/proteoglycans produced by two human colon cancer cell lines
    • Chatzinikolaou, G.; Nikitovic, D.; Stathopoulos, E.N.; Velegrakis, G.A.; Karamanos, N.K.; Tzanakakis, G.N. Protein tyrosine kinase and estrogen receptor-dependent pathways regulate the synthesis and distribution of glycosaminoglycans/proteoglycans produced by two human colon cancer cell lines. Anticancer Res., 2007, 27, 4101-4106
    • (2007) Anticancer Res. , vol.27 , pp. 4101-4106
    • Chatzinikolaou, G.1    Nikitovic, D.2    Stathopoulos, E.N.3    Velegrakis, G.A.4    Karamanos, N.K.5    Tzanakakis, G.N.6
  • 32
    • 0029896318 scopus 로고    scopus 로고
    • Hyaluronan distribution in the normal epithelium of esophagus, stomach, and colon and their cancers
    • Wang, C.; Tammi, M.; Guo, H. Tammi, R. Hyaluronan distribution in the normal epithelium of esophagus, stomach, and colon and their cancers, Am J Pathol., 148, 1861-1869.
    • Am J Pathol. , vol.148 , pp. 1861-1869
    • Wang, C.1    Tammi, M.2    Guo, H.3    Tammi, R.4
  • 33
    • 47549100061 scopus 로고    scopus 로고
    • Association of loss of epithelial syndecan-1 with stage and local metastasis of colorectal adenocarcinomas: An immunohistochemical study of clinically annotated tumors
    • doi: 10.1186/1471-2407-8-18
    • Hashimoto, Y.; Skacel, M.; Adams, J.C. Association of loss of epithelial syndecan-1 with stage and local metastasis of colorectal adenocarcinomas: an immunohistochemical study of clinically annotated tumors. BMC Cancer, 2008, 8:185. doi: 10.1186/1471-2407-8-18
    • (2008) BMC Cancer , vol.8 , pp. 185
    • Hashimoto, Y.1    Skacel, M.2    Adams, J.C.3
  • 34
    • 54249114166 scopus 로고    scopus 로고
    • Immunohistochemical study of decorin expression in polyps and carcinomas of the colon
    • Augoff, K.; Rabczynski, J.; Tabola, R.; Czapla, L.; Ratajczak, K.; Grabowski, "Immunohistochemical study of decorin expression in polyps and carcinomas of the colon, " Med Sci. Monit., 2008, 14, CR530-535
    • (2008) Med Sci. Monit. , vol.14
    • Augoff, K.1    Rabczynski, J.2    Tabola, R.3    Czapla, L.4    Ratajczak, K.5    Grabowski6
  • 36
    • 0036819199 scopus 로고    scopus 로고
    • Mammalian hyaluronan synthases
    • Itano, N.; Kimata, K. Mammalian hyaluronan synthases. IUBMB Life, 2002, 54, 195-199
    • (2002) IUBMB Life , vol.54 , pp. 195-199
    • Itano, N.1    Kimata, K.2
  • 37
    • 0035202430 scopus 로고    scopus 로고
    • The six hyaluronidase-like genes in the human and mouse genomes
    • Csoka, A.; Frost, G.; Stern, R. The six hyaluronidase-like genes in the human and mouse genomes. Matrix Biol., 2001, 20, 499-508
    • (2001) Matrix Biol. , vol.20 , pp. 499-508
    • Csoka, A.1    Frost, G.2    Stern, R.3
  • 38
    • 0037085372 scopus 로고    scopus 로고
    • Hyaluronan-binding proteins: Tying up the giant
    • J Biol Chem
    • Day, A. J.; Prestwich, G. D. J Biol Chem. Hyaluronan-binding proteins: tying up the giant. J. Biol. Chem., 2002, 277, 4585-4588
    • (2002) J. Biol. Chem. , vol.277 , pp. 4585-4588
    • Day, A.J.1    Prestwich, G.D.2
  • 39
    • 0035444147 scopus 로고    scopus 로고
    • Hyaluronan: Polysaccharide chaos to protein organisation
    • Day AJ, Sheehan JK. Hyaluronan: polysaccharide chaos to protein organisation. Curr. Opin. Struc. Biol., 2001, 11, 617-622
    • (2001) Curr. Opin. Struc. Biol. , vol.11 , pp. 617-622
    • Day, A.J.1    Sheehan, J.K.2
  • 40
    • 3042697038 scopus 로고    scopus 로고
    • Hyaluronan: From extracellular glue to pericellular cue
    • Toole BP. Hyaluronan: from extracellular glue to pericellular cue. Nat. Rev. Cancer, 2004, 4, 528-539
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 528-539
    • Toole, B.P.1
  • 42
    • 22844432511 scopus 로고    scopus 로고
    • Towards a structure for a TSG-6.hyaluronan complex by modeling and NMR spectroscopy: Insights into other members of the link module superfamily
    • Blundell, C.D.; Almond, A.; Mahoney, D.J.; DeAngelis, P.L.; Campbell, I.D.; Day, A.J. Towards a structure for a TSG-6.hyaluronan complex by modeling and NMR spectroscopy: insights into other members of the link module superfamily. J. Bio.l Chem., 2005, 280, 18189-18201
    • (2005) J. Bio.l Chem. , vol.280 , pp. 18189-18201
    • Blundell, C.D.1    Almond, A.2    Mahoney, D.J.3    Deangelis, P.L.4    Campbell, I.D.5    Day, A.J.6
  • 43
    • 0030690228 scopus 로고    scopus 로고
    • Requirement for CD44 in activated T cell extravasation into an inflammatory site
    • De Grendele, H.C.; Estess, P.; Siegelman, M.H. Requirement for CD44 in activated T cell extravasation into an inflammatory site. Science, 1997, 278, 672-675
    • (1997) Science , vol.278 , pp. 672-675
    • De Grendele, H.C.1    Estess, P.2    Siegelman, M.H.3
  • 44
    • 0036731866 scopus 로고    scopus 로고
    • Hyaluronan and tumor growth
    • Toole, B.P.; Hascall, V.C. Hyaluronan and tumor growth. Am J Pathol., 2002, 161, 745-747.
    • (2002) Am J Pathol. , vol.161 , pp. 745-747
    • Toole, B.P.1    Hascall, V.C.2
  • 45
    • 77954938543 scopus 로고    scopus 로고
    • Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal squamous carcinoma cells
    • Twarock, S.; Tammi, M.I.; Savani, R.C.; Fischer, J.W. Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal squamous carcinoma cells. J. Bio.l Chem., 2010, 285, 23276-23284
    • (2010) J. Bio.l Chem. , vol.285 , pp. 23276-23284
    • Twarock, S.1    Tammi, M.I.2    Savani, R.C.3    Fischer, J.W.4
  • 48
    • 0033964912 scopus 로고    scopus 로고
    • CD44s expression in human colon carcinomas influences growth of liver metastases
    • Choi, S.H.; Takahashi, K.; Eto, H.; Yoon, S.S.; Tanabe, K.K. CD44s expression in human colon carcinomas influences growth of liver metastases. Int. J. Cancer, 2000, 85, 523-526
    • (2000) Int. J. Cancer , vol.85 , pp. 523-526
    • Choi, S.H.1    Takahashi, K.2    Eto, H.3    Yoon, S.S.4    Tanabe, K.K.5
  • 49
    • 33748846786 scopus 로고    scopus 로고
    • Overexpression of the receptor for hyaluronic acid mediated motility is an independent adverse prognostic factor in colorectal cancer
    • Lugli, A.; Zlobec, I. Overexpression of the receptor for hyaluronic acid mediated motility is an independent adverse prognostic factor in colorectal cancer. Mod. Pathol., 2006, 19, 1302-1309
    • (2006) Mod. Pathol. , vol.19 , pp. 1302-1309
    • Lugli, A.1    Zlobec, I.2
  • 50
    • 44749083057 scopus 로고    scopus 로고
    • Hyaluronan in human tumors: Pathobiological and prognostic messages from cell-associated and stromal hyaluronan
    • Tammi, R.H.; Kultti, A.; Kosma, V.M.; Pirinen, R.; Auvinen, P.; Tammi, M.I. Hyaluronan in human tumors: pathobiological and prognostic messages from cell-associated and stromal hyaluronan. Semin. Cancer Biol., 2008, 18, 288-295
    • (2008) Semin. Cancer Biol. , vol.18 , pp. 288-295
    • Tammi, R.H.1    Kultti, A.2    Kosma, V.M.3    Pirinen, R.4    Auvinen, P.5    Tammi, M.I.6
  • 51
    • 9944222565 scopus 로고    scopus 로고
    • Epithelial hyaluronic acid and CD44v6 are mutually involved in invasion of colorectal adenocarcinomas and linked to patient prognosis
    • Köbel, M.; Weichert, W.; Cruwell, K.; Schmitt, W.D.; Lautenschlager, C.; Hauptmann. S. Epithelial hyaluronic acid and CD44v6 are mutually involved in invasion of colorectal adenocarcinomas and linked to patient prognosis Virchows Arch. 2004, 445, 456-464
    • (2004) Virchows Arch. , vol.445 , pp. 456-464
    • Köbel, M.1    Weichert, W.2    Cruwell, K.3    Schmitt, W.D.4    Lautenschlager, C.5    Hauptmann, S.6
  • 52
    • 0242332100 scopus 로고    scopus 로고
    • Hyaluronan synthase-3 is upregulated in metastatic colon carcinoma cells and manipulation of expression alters matrix retention and cellular growth
    • Bullard, K.M.; Kim, H.R.; Wheeler, M.A.; Wilson, C.M.; Neudauer, C.L, .; Simpson, M.A.; McCarthy, J.B. Hyaluronan synthase-3 is upregulated in metastatic colon carcinoma cells and manipulation of expression alters matrix retention and cellular growth. Int. J. Cancer, 2003, 107, 739-746
    • (2003) Int. J. Cancer , vol.107 , pp. 739-746
    • Bullard, K.M.1    Kim, H.R.2    Wheeler, M.A.3    Wilson, C.M.4    Neudauer, C.L.5    Simpson, M.A.6    McCarthy, J.B.7
  • 55
    • 0037145745 scopus 로고    scopus 로고
    • Expression of hyaluronan synthase 2 or hyaluronidase 1 differentially affect the growth rate of transplantable colon carcinoma cell tumors
    • Jacobson, A.; Rahmanian, M.; Rubin, K.; Heldin, P. Expression of hyaluronan synthase 2 or hyaluronidase 1 differentially affect the growth rate of transplantable colon carcinoma cell tumors. Int J Cancer, 2002, 102, 212-219.
    • (2002) Int J Cancer , vol.102 , pp. 212-219
    • Jacobson, A.1    Rahmanian, M.2    Rubin, K.3    Heldin, P.4
  • 64
    • 85027938316 scopus 로고    scopus 로고
    • Discriminant function based on parameters of hyaluronic acid metabolism and nitric oxide to differentiate metastatic from non-metastatic colorectal cancer patients
    • Jan 26. [Epub ahead of print]
    • El-Mezayen, H.A.; Toson, E.S.; Darwish, H.; El-Badry, E. Discriminant function based on parameters of hyaluronic acid metabolism and nitric oxide to differentiate metastatic from non-metastatic colorectal cancer patients. Tumour Biol., 2012 Jan 26. [Epub ahead of print].
    • (2012) Tumour Biol.
    • El-Mezayen, H.A.1    Toson, E.S.2    Darwish, H.3    El-Badry, E.4
  • 67
    • 0031972103 scopus 로고    scopus 로고
    • Expression of CD44 and variant proteins in human colorectal cancer and its relevance for prognosis
    • Ropponen, K.M.; Eskelinen, M.J.; Lipponen, P.K.; Alhava, E.; Kosma, V.M. Expression of CD44 and variant proteins in human colorectal cancer and its relevance for prognosis. Scand. J. Gastroenterol., 1998, 33, 301-309
    • (1998) Scand. J. Gastroenterol. , vol.33 , pp. 301-309
    • Ropponen, K.M.1    Eskelinen, M.J.2    Lipponen, P.K.3    Alhava, E.4    Kosma, V.M.5
  • 68
    • 70350752040 scopus 로고    scopus 로고
    • Frequent expression of the high molecular, 673-bp CD44v3, v8-10 variant in colorectal adenomas and carcinomas
    • Kopp, R.; Fichter, M.; Schalhorn, G.; Danescu, J.; Classen. S. Frequent expression of the high molecular, 673-bp CD44v3, v8-10 variant in colorectal adenomas and carcinomas. Int. J. Mol. Med., 2009, 24, 677-683
    • (2009) Int. J. Mol. Med. , vol.24 , pp. 677-683
    • Kopp, R.1    Fichter, M.2    Schalhorn, G.3    Danescu, J.4    Classen, S.5
  • 69
    • 0033812645 scopus 로고    scopus 로고
    • Loss of standard type of CD44 expression in invaded area as a good indicator of lymph-node metastasis in colorectal carcinoma
    • Asao, T.; Nakamura, J.; Shitara, Y.; Tsutsumi, S.; Mochiki, E.; Shimura, T.; Takenoshita, S.; Kuwano, H. Loss of standard type of CD44 expression in invaded area as a good indicator of lymph-node metastasis in colorectal carcinoma. Dis. Colon Rectum., 2000, 43, 1250-1254
    • (2000) Dis. Colon Rectum. , vol.43 , pp. 1250-1254
    • Asao, T.1    Nakamura, J.2    Shitara, Y.3    Tsutsumi, S.4    Mochiki, E.5    Shimura, T.6    Takenoshita, S.7    Kuwano, H.8
  • 70
    • 0035983872 scopus 로고    scopus 로고
    • TNFalpha and IL-8 regulate the expression and function of CD44 variant proteins in human colon carcinoma cells
    • Barshishat, M.; Ariel, A.; Cahalon, L.; Chowers, Y.; Lider, O.; Schwartz, B. TNFalpha and IL-8 regulate the expression and function of CD44 variant proteins in human colon carcinoma cells. Clin. Exp. Metastasis, 2002, 19, 327-337
    • (2002) Clin. Exp. Metastasis , vol.19 , pp. 327-337
    • Barshishat, M.1    Ariel, A.2    Cahalon, L.3    Chowers, Y.4    Lider, O.5    Schwartz, B.6
  • 71
    • 0029825416 scopus 로고    scopus 로고
    • Regulated clustering of variant CD44 proteins increases their hyaluronate binding capacity
    • Sleeman, J; Rudy W.; Hofmann, M.; Moll, J.; Herrlich, P.; Ponta, H. Regulated clustering of variant CD44 proteins increases their hyaluronate binding capacity. J. Cell Biol., 1996, 135, 1139-1150
    • (1996) J. Cell Biol. , vol.135 , pp. 1139-1150
    • Sleeman, J.1    Rudy, W.2    Hofmann, M.3    Moll, J.4    Herrlich, P.5    Ponta, H.6
  • 72
    • 15744372318 scopus 로고    scopus 로고
    • Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells
    • Ghatak, S.; Misra, S.; Toole, B.P. Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells. J. Biol Chem., 2005, 280, 8875-8883
    • (2005) J. Biol Chem. , vol.280 , pp. 8875-8883
    • Ghatak, S.1    Misra, S.2    Toole, B.P.3
  • 73
    • 47249092311 scopus 로고    scopus 로고
    • Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells
    • Misra, S.; Obeid, L.M.; Hannun, Y.A.; Minamisawa, S.; Berger, F.G.; Markwald, R.R.; Toole, B.P.; Ghatak, S. Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells. J. Biol. Chem., 2008, 283, 14335-143442
    • (2008) J. Biol. Chem. , vol.283 , pp. 14335-143442
    • Misra, S.1    Obeid, L.M.2    Hannun, Y.A.3    Minamisawa, S.4    Berger, F.G.5    Markwald, R.R.6    Toole, B.P.7    Ghatak, S.8
  • 74
    • 66449110672 scopus 로고    scopus 로고
    • Delivery of CD44 shRNA/nanoparticles within cancer cells: Perturbation of hyaluronan/CD44v6 interactions and reduction in adenoma growth in Apc Min/+ MICE
    • Misra, S.; Hascall, V.C.; De Giovanni, C.; Markwald, R.R.; Ghatak, S. Delivery of CD44 shRNA/nanoparticles within cancer cells: perturbation of hyaluronan/CD44v6 interactions and reduction in adenoma growth in Apc Min/+ MICE. J. Biol. Chem., 2009, 284, 12432-1446
    • (2009) J. Biol. Chem. , vol.284 , pp. 12432-21446
    • Misra, S.1    Hascall, V.C.2    De Giovanni, C.3    Markwald, R.R.4    Ghatak, S.5
  • 75
    • 77953611147 scopus 로고    scopus 로고
    • Cyclooxygenase-2 in tumorigenesis of gastrointestinal cancers: An update on the molecular mechanisms
    • Wu, W.K.; Sung, J.J.; Lee, C.W.; Yu, J.; Cho, C.H. Cyclooxygenase-2 in tumorigenesis of gastrointestinal cancers: an update on the molecular mechanisms. Cancer Lett., 2010, 295, 7-16
    • (2010) Cancer Lett. , vol.295 , pp. 7-16
    • Wu, W.K.1    Sung, J.J.2    Lee, C.W.3    Yu, J.4    Cho, C.H.5
  • 76
    • 2342591455 scopus 로고    scopus 로고
    • The discovery of receptor tyrosine kinases: Targets for cancer therapy
    • Gschwind, A.; Fischer, O.M.; Ullrich, A. The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat. Rev. Cancer, 2004, 4, 361-370
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 361-370
    • Gschwind, A.1    Fischer, O.M.2    Ullrich, A.3
  • 77
    • 33845951437 scopus 로고    scopus 로고
    • Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells
    • Misra, S.; Toole, B.P, ; Ghatak, S. Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells. J. Biol. Chem, 2006, 281, 34936-34941
    • (2006) J. Biol. Chem , vol.281 , pp. 34936-34941
    • Misra, S.1    Toole, B.P.2    Ghatak, S.3
  • 78
    • 33646250437 scopus 로고    scopus 로고
    • Proteomic analysis of differentially expressed proteins in fungal elicitor-treated Arabidopsis cell cultures
    • Chivasa, S.; Hamilton, J.M.; Pringle, R.S.; Ndimba, B.K.; Simon, W.J.; Lindsey, K.; Slabas, A.R. Proteomic analysis of differentially expressed proteins in fungal elicitor-treated Arabidopsis cell cultures. J. Exp. Bot., 2006, 57, 1553-1562
    • (2006) J. Exp. Bot. , vol.57 , pp. 1553-1562
    • Chivasa, S.1    Hamilton, J.M.2    Pringle, R.S.3    Ndimba, B.K.4    Simon, W.J.5    Lindsey, K.6    Slabas, A.R.7
  • 79
    • 0029828693 scopus 로고    scopus 로고
    • The characterization of a human RHAMM cDNA: Conservation of the hyaluronan-binding domains
    • Wang, C.; Entwistle, J.; Hou, G.; Li, Q.; Turley, E.A. The characterization of a human RHAMM cDNA: conservation of the hyaluronan-binding domains. Gene, 1996, 174, 299-306
    • (1996) Gene , vol.174 , pp. 299-306
    • Wang, C.1    Entwistle, J.2    Hou, G.3    Li, Q.4    Turley, E.A.5
  • 80
    • 43149106462 scopus 로고    scopus 로고
    • Cell-surface and mitotic-spindle RHAMM: Moonlighting or dual oncogenic functions?
    • Maxwell, C.A.; McCarthy, J.; Turley, E. Cell-surface and mitotic-spindle RHAMM: moonlighting or dual oncogenic functions? J. Cell Sci., 2008, 121, 925-932
    • (2008) J. Cell Sci. , vol.121 , pp. 925-932
    • Maxwell, C.A.1    McCarthy, J.2    Turley, E.3
  • 82
    • 0032735286 scopus 로고    scopus 로고
    • Receptor for hyaluronan-mediated motility and CD44 expressions in colon cancer assessed by quantitative analysis using real-time reverse transcriptase-polymerase chain reaction
    • Yamada, Y.; Itano, N.; Narimatsu, H.; Kudo, T.; Hirohashi, S.; Ochiai, A.; Niimi, A.; Ueda, M.; Kimata, K.N. Receptor for hyaluronan-mediated motility and CD44 expressions in colon cancer assessed by quantitative analysis using real-time reverse transcriptase-polymerase chain reaction. Jpn. J. Cancer Res., 1999, 90, 987-992
    • (1999) Jpn. J. Cancer Res. , vol.90 , pp. 987-992
    • Yamada, Y.1    Itano, N.2    Narimatsu, H.3    Kudo, T.4    Hirohashi, S.5    Ochiai, A.6    Niimi, A.7    Ueda, M.8    Kimata, K.N.9
  • 84
    • 55949134332 scopus 로고    scopus 로고
    • Two-marker protein profile predicts poor prognosis in patients with early rectal cancer
    • Zlobec, I.; Baker, K.; Terracciano, L.; Peter, S.; Degen, L.;, Beglinger C.; Lugli, A. Two-marker protein profile predicts poor prognosis in patients with early rectal cancer. Br. J. Cancer, 2008, 99, 1712-1717
    • (2008) Br. J. Cancer , vol.99 , pp. 1712-1717
    • Zlobec, I.1    Baker, K.2    Terracciano, L.3    Peter, S.4    Degen, L.5    Beglinger, C.6    Lugli, A.7
  • 85
    • 52649176459 scopus 로고    scopus 로고
    • Role of RHAMM within the hierarchy of well-established prognostic factors in colorectal cancer
    • Zlobec, I.; Terracciano, L.; Tornillo, L.; Günthert, U.; Vuong, T.; Jass, J.R.; Lugli, A. Role of RHAMM within the hierarchy of well-established prognostic factors in colorectal cancer. Gut, 2008, 57, 1413-1419
    • (2008) Gut , vol.57 , pp. 1413-1419
    • Zlobec, I.1    Terracciano, L.2    Tornillo, L.3    Günthert, U.4    Vuong, T.5    Jass, J.R.6    Lugli, A.7
  • 87
    • 79955054709 scopus 로고    scopus 로고
    • Regulatory roles of hyaluronan in health and disease
    • Hascall, V.; Karamanos N. Regulatory roles of hyaluronan in health and disease. FEBS J., 2011, 278, 1411
    • (2011) FEBS J , vol.278 , pp. 1411
    • Hascall, V.1    Karamanos, N.2
  • 88
    • 0037227965 scopus 로고    scopus 로고
    • CD44: From adhesion molecules to signaling regulators
    • Ponta, H.; Sherman, L.; Herrlich, P.A. CD44: from adhesion molecules to signaling regulators. Nat. Mol. Cell Biol., 2003, 4, 33-45
    • (2003) Nat. Mol. Cell Biol. , vol.4 , pp. 33-45
    • Ponta, H.1    Sherman, L.2    Herrlich, P.A.3
  • 89
    • 36049048637 scopus 로고    scopus 로고
    • Suppression of human colon cancer tumors in nude mice by siRNA CD44 gene therapy
    • Subramaniam, V.; Vincent, I.R.; Gilakjan, M.; Jothy, S. Suppression of human colon cancer tumors in nude mice by siRNA CD44 gene therapy. Exp. Mol. Pathol., 2007, 83, 332-340
    • (2007) Exp. Mol. Pathol. , vol.83 , pp. 332-340
    • Subramaniam, V.1    Vincent, I.R.2    Gilakjan, M.3    Jothy, S.4
  • 90
    • 84862933195 scopus 로고    scopus 로고
    • ShRNA against CD44 inhibits cell proliferation, invasion and migration, and promotes apoptosis of colon carcinoma cells
    • Park, Y.S.; Huh, J.W.; Lee, J.H.; Kim, H.R. shRNA against CD44 inhibits cell proliferation, invasion and migration, and promotes apoptosis of colon carcinoma cells. Oncol. Rep., 2012, 27, 339-346
    • (2012) Oncol. Rep. , vol.27 , pp. 339-346
    • Park, Y.S.1    Huh, J.W.2    Lee, J.H.3    Kim, H.R.4
  • 91
    • 79957467315 scopus 로고    scopus 로고
    • Molecular identification and targeting of colorectal cancer stem cells
    • Kemper, K.; Grandela, C.; Medema, J.P. Molecular identification and targeting of colorectal cancer stem cells. Oncotarget, 2010, 1, 387-395.
    • (2010) Oncotarget , vol.1 , pp. 387-395
    • Kemper, K.1    Grandela, C.2    Medema, J.P.3
  • 92
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham, D.; Humblet, Y.; Siena, S.; et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N. Engl. J. Med., 2004, 351, 337-345
    • (2004) N. Engl. J. Med. , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 93
    • 13744251436 scopus 로고    scopus 로고
    • Systemic therapy for colorectal cancer
    • Meyerhardt, J.A.; Mayer, R.J. Systemic therapy for colorectal cancer. N. Engl. J Med., 2005, 352, 476-487
    • (2005) N. Engl. J Med. , vol.352 , pp. 476-487
    • Meyerhardt, J.A.1    Mayer, R.J.2
  • 96
    • 0034947648 scopus 로고    scopus 로고
    • Molecular diversity of heparan sulfate
    • Esko, J.D.; Lindahl, U. Molecular diversity of heparan sulfate. Clin. Invest., 2001, 108, 169-173
    • (2001) Clin. Invest. , vol.108 , pp. 169-173
    • Esko, J.D.1    Lindahl, U.2
  • 97
    • 77956618577 scopus 로고    scopus 로고
    • Tumorigenic and adhesive properties of heparanase
    • Levy-Adam, F.; Ilan, N.; Vlodavsky, I. Tumorigenic and adhesive properties of heparanase. Semin. Cancer Biol., 2010, 20, 153-160
    • (2010) Semin. Cancer Biol. , vol.20 , pp. 153-160
    • Levy-Adam, F.1    Ilan, N.2    Vlodavsky, I.3
  • 98
    • 33746614761 scopus 로고    scopus 로고
    • Interactions between heparan sulfate and proteins: The concept of specificity
    • Kreuger J, Spillmann D, Li JP, Lindahl U. Interactions between heparan sulfate and proteins: the concept of specificity. J. Cell Biol. 2006, 174, 323-327
    • (2006) J. Cell Biol. , vol.174 , pp. 323-327
    • Kreuger, J.1    Spillmann, D.2    Li, J.P.3    Lindahl, U.4
  • 99
    • 77950833141 scopus 로고    scopus 로고
    • Tumor biology of heparan sulfate proteoglycans
    • Raman, K.; Kuberan, B. Tumor Biology of Heparan Sulfate Proteoglycans. Cur.r Chem. Biol., 2010, 4, 20-31
    • (2010) Cur.r Chem. Biol. , vol.4 , pp. 20-31
    • Raman, K.1    Kuberan, B.2
  • 100
    • 79956226810 scopus 로고    scopus 로고
    • SULFs in human neoplasia: Implication as progression and prognosis factors
    • doi: 10.1186/1479-5876-9-72
    • Bret, C.; Moreaux, J.; Schved, J.F.; Hose, D.; Klein, B. SULFs in human neoplasia: implication as progression and prognosis factors. J. Transl. Med., 2011, 9:72. doi: 10.1186/1479-5876-9-72
    • (2011) J. Transl. Med. , vol.9 , pp. 72
    • Bret, C.1    Moreaux, J.2    Schved, J.F.3    Hose, D.4    Klein, B.5
  • 101
    • 0036591497 scopus 로고    scopus 로고
    • Ectopic expression of a GlcNAc 6-O-sulfotransferase, GlcNAc6ST-2, in colonic mucinous adenocarcinoma
    • Seko, A.; Nagata, K; Yonezawa, S.; Yamashita, K. Ectopic expression of a GlcNAc 6-O-sulfotransferase, GlcNAc6ST-2, in colonic mucinous adenocarcinoma. Glycobiology, 2002, 12, 379-388
    • (2002) Glycobiology , vol.12 , pp. 379-388
    • Seko, A.1    Nagata, K.2    Yonezawa, S.3    Yamashita, K.4
  • 102
    • 0030906030 scopus 로고    scopus 로고
    • Oncogenic activation of p21ras or pp60c-src in human colonic Caco-2 cells induces post-translation alterations of syndecan-1
    • Lévy, P.; Munier, A.; Baron-Delage, S.; Chastre, E.; Gespach, C.; Capeau, J.; Cherqui, G. Oncogenic activation of p21ras or pp60c-src in human colonic Caco-2 cells induces post-translation alterations of syndecan-1. Bull Cancer, 1997, 84, 235-237
    • (1997) Bull Cancer , vol.84 , pp. 235-237
    • Lévy, P.1    Munier, A.2    Baron-Delage, S.3    Chastre, E.4    Gespach, C.5    Capeau, J.6    Cherqui, G.7
  • 104
    • 0033810052 scopus 로고    scopus 로고
    • Expression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma
    • Friedmann, Y.; Vlodavsky, I.; Aingorn, H.; Aviv, A.; Peretz, T.; Pecker, I.; Pappo, O. Expression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma. Am. J. Pathol., 2000, 157, 1167-1175
    • (2000) Am. J. Pathol. , vol.157 , pp. 1167-1175
    • Friedmann, Y.1    Vlodavsky, I.2    Aingorn, H.3    Aviv, A.4    Peretz, T.5    Pecker, I.6    Pappo, O.7
  • 105
    • 33646879997 scopus 로고    scopus 로고
    • Spatial and temporal heparanase expression in colon mucosa throughout the adenoma-carcinoma sequence
    • Doviner, V.; Maly, B.; Kaplan, V.; Gingis-Velitski, S.; Ilan, N.; Vlodavsky, ; Sherman. Y. Spatial and temporal heparanase expression in colon mucosa throughout the adenoma-carcinoma sequence. Mod. Pathol., 2006, 19, 878-888
    • (2006) Mod. Pathol. , vol.19 , pp. 878-888
    • Doviner, V.1    Maly, B.2    Kaplan, V.3    Gingis-Velitski, S.4    Ilan, N.5    Vlodavsky6    Sherman, Y.7
  • 108
    • 73849090217 scopus 로고    scopus 로고
    • IKK/NF-kappaB and STAT3 pathways: Central signaling hubs in inflammation-mediated tumour promotion and metastasis
    • Bollrath, J.; Greten, F.R. IKK/NF-kappaB and STAT3 pathways: central signaling hubs in inflammation-mediated tumour promotion and metastasis. EMBO Rep., 2009, 10, 1314-1319
    • (2009) EMBO Rep. , vol.10 , pp. 1314-1319
    • Bollrath, J.1    Greten, F.R.2
  • 109
    • 77953479589 scopus 로고    scopus 로고
    • Inflammatory bowel disease and intestinal cancer: A paradigm of the Yin-Yang interplay between inflammation and cancer
    • Danese, S.; Mantovani, A. Inflammatory bowel disease and intestinal cancer: a paradigm of the Yin-Yang interplay between inflammation and cancer. Oncogene, 2010, 29, 3313-3323
    • (2010) Oncogene , vol.29 , pp. 3313-3323
    • Danese, S.1    Mantovani, A.2
  • 111
    • 50249117779 scopus 로고    scopus 로고
    • EXTL3 promoter methylation down-regulates EXTL3 and heparan sulphate expression in mucinous colorectal cancers
    • Karibe, T.; Fukui, H.; Sekikawa, A.; Shiratori, K.; Fujimori, T. EXTL3 promoter methylation down-regulates EXTL3 and heparan sulphate expression in mucinous colorectal cancers. J. Pathol., 2008, 216, 32-42
    • (2008) J. Pathol. , vol.216 , pp. 32-42
    • Karibe, T.1    Fukui, H.2    Sekikawa, A.3    Shiratori, K.4    Fujimori, T.5
  • 112
    • 0031982631 scopus 로고    scopus 로고
    • Heparan sulfate undergoes specific structural changes during the progression from human colon adenoma to carcinoma in vitro
    • Jayson, G.C.; Lyon, M.; Paraskeva, C.; Turnbull, J.E.; Deakin, J.A.; Gallagher, J.T. Heparan sulfate undergoes specific structural changes during the progression from human colon adenoma to carcinoma in vitro. J. Biol. Chem., 1998, 273, 51-57
    • (1998) J. Biol. Chem. , vol.273 , pp. 51-57
    • Jayson, G.C.1    Lyon, M.2    Paraskeva, C.3    Turnbull, J.E.4    Deakin, J.A.5    Gallagher, J.T.6
  • 114
    • 0028345937 scopus 로고
    • Heparin stimulates the proliferation of intestinal epithelial cells in primary culture
    • Flint, N.; Cove, F.L.; Evans, G.S. Heparin stimulates the proliferation of intestinal epithelial cells in primary culture. J. Cell Sci., 1994, 107(2), 401-411
    • (1994) J. Cell Sci. , vol.107 , Issue.2 , pp. 401-411
    • Flint, N.1    Cove, F.L.2    Evans, G.S.3
  • 115
    • 0037052642 scopus 로고    scopus 로고
    • Heparin-derived disaccharides modulate proliferation and Erb-B2-mediated signal transduction in colon cancer cell lines
    • Fishman, S.; Brill, S.; Papa, M.; Halpern, Z.; Zvibel, I. "Heparin-derived disaccharides modulate proliferation and Erb-B2-mediated signal transduction in colon cancer cell lines, " Int. J. Cancer, 2002, 99, 179-184
    • (2002) Int. J. Cancer , vol.99 , pp. 179-184
    • Fishman, S.1    Brill, S.2    Papa, M.3    Halpern, Z.4    Zvibel, I.5
  • 117
    • 0035254952 scopus 로고    scopus 로고
    • Soluble and matrix-associated heparan sulfate proteoglycans increase expression of erb-B2 and erb-B3 in colon cancer cell lines
    • Zvibel, I., Brill, S.; Halpern, Z.; Moskovitz, S.; Yayon, A.; Papa, M. Soluble and matrix-associated heparan sulfate proteoglycans increase expression of erb-B2 and erb-B3 in colon cancer cell lines. Int. J. Cancer, 2001, 91, 316-321
    • (2001) Int. J. Cancer , vol.91 , pp. 316-321
    • Zvibel, I.1    Brill, S.2    Halpern, Z.3    Moskovitz, S.4    Yayon, A.5    Papa, M.6
  • 118
    • 0033403227 scopus 로고    scopus 로고
    • Amphiregulin and hepatocytederived extracellular matrix regulate proliferation and autocrine growth factor expression in colon cancer cell lines of varying liver-colonizing capability
    • Zvibel, I.; Brill, S.; Halpern, Z.; Papa, M. Amphiregulin and hepatocytederived extracellular matrix regulate proliferation and autocrine growth factor expression in colon cancer cell lines of varying liver-colonizing capability. J. Cell Biochem., 1999, 76, 332-340
    • (1999) J. Cell Biochem. , vol.76 , pp. 332-340
    • Zvibel, I.1    Brill, S.2    Halpern, Z.3    Papa, M.4
  • 120
    • 0033050810 scopus 로고    scopus 로고
    • Coordinated modulation of the fibroblast growth factor dual receptor mechanism during transformation from human colon adenoma to carcinoma
    • Jayson, G.C.; Vives, C.; Paraskeva, C.; Schofield, K.; Coutts, J.; Fleetwood, A.; Gallagher, JT. Coordinated modulation of the fibroblast growth factor dual receptor mechanism during transformation from human colon adenoma to carcinoma. Int. J. Cancer, 1999, 82, 298-304
    • (1999) Int. J. Cancer , vol.82 , pp. 298-304
    • Jayson, G.C.1    Vives, C.2    Paraskeva, C.3    Schofield, K.4    Coutts, J.5    Fleetwood, A.6    Gallagher, J.T.7
  • 121
    • 0035674835 scopus 로고    scopus 로고
    • Heparan sulfate enhances invasion by human colon carcinoma cell lines through expression of CD44 variant exon 3
    • Kuniyasu, H.; Oue, N.; Tsutsumi, M.; Tahara, E.; Yasui, W. Heparan sulfate enhances invasion by human colon carcinoma cell lines through expression of CD44 variant exon 3. Clin Cancer Res., 2001, 7, 4067-4072.
    • (2001) Clin Cancer Res. , vol.7 , pp. 4067-4072
    • Kuniyasu, H.1    Oue, N.2    Tsutsumi, M.3    Tahara, E.4    Yasui, W.5
  • 123
    • 0037119429 scopus 로고    scopus 로고
    • Syndecan-2 mediates adhesion and proliferation of colon carcinoma cells
    • Park, H.; Kim, Y.; Lim, Y.; Han, I.; Oh, E.S. Syndecan-2 mediates adhesion and proliferation of colon carcinoma cells. J. Biol. Chem., 2002, 277, 29730-29736
    • (2002) J. Biol. Chem. , vol.277 , pp. 29730-29736
    • Park, H.1    Kim, Y.2    Lim, Y.3    Han, I.4    Oh, E.S.5
  • 125
    • 79956194358 scopus 로고    scopus 로고
    • Syndecan-2 cytoplasmic domain regulates colon cancer cell migration via interaction with syntenin-1
    • Lee, H.; Kim, Y.; Choi, Y.; Choi, S.; Hong, E.; Oh, E.S. Syndecan-2 cytoplasmic domain regulates colon cancer cell migration via interaction with syntenin-1. Biochem. Biophys. Res. Commun., 2011, 409, 148-153
    • (2011) Biochem. Biophys. Res. Commun. , vol.409 , pp. 148-153
    • Lee, H.1    Kim, Y.2    Choi, Y.3    Choi, S.4    Hong, E.5    Oh, E.S.6
  • 126
    • 74949093867 scopus 로고    scopus 로고
    • An immunohistochemical study of colon adenomas and carcinomas: E-cadherin, Syndecan-1, Ets-1
    • Pap, Z.; Pávai, Z.; Dénes, L.; Kovalszky, I.; Jung, J. An immunohistochemical study of colon adenomas and carcinomas: E-cadherin, Syndecan-1, Ets-1. Pathol. Oncol. Res., 2009, 15, 579-587
    • (2009) Pathol. Oncol. Res. , vol.15 , pp. 579-587
    • Pap, Z.1    Pávai, Z.2    Dénes, L.3    Kovalszky, I.4    Jung, J.5
  • 128
    • 79951676056 scopus 로고    scopus 로고
    • PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models
    • Dredge, K.; Hammond, E.; Handley, P.; Gonda, T.J.; Smith, M.T.; Vincent, C.; Brandt, R.; Ferro, V.; Bytheway, I. PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models. Br. J. Cancer, 2011, 104, 635-642
    • (2011) Br. J. Cancer , vol.104 , pp. 635-642
    • Dredge, K.1    Hammond, E.2    Handley, P.3    Gonda, T.J.4    Smith, M.T.5    Vincent, C.6    Brandt, R.7    Ferro, V.8    Bytheway, I.9
  • 130
    • 36049013035 scopus 로고    scopus 로고
    • Heparin attenuates metastasis mainly due to inhibition of P-and L-selectin, but non-anticoagulant heparins can have additional effects
    • Stevenson, J.L.; Varki, A.; Borsig, L Heparin attenuates metastasis mainly due to inhibition of P-and L-selectin, but non-anticoagulant heparins can have additional effects. Thromb. Res., 2007, 120, S107-111
    • (2007) Thromb. Res. , vol.120
    • Stevenson, J.L.1    Varki, A.2    Borsig, L.3
  • 131
    • 0035853111 scopus 로고    scopus 로고
    • Heparin and cancer revisited: Mechanistic connections involving platelets. Pselectin, carcinoma mucins, and tumor metastasis
    • Borsig, L.; Wong, R; Feramisco, J, ; Nadeau, D.R.; Varki, N.M.; Varki, A. Heparin and cancer revisited: mechanistic connections involving platelets. Pselectin, carcinoma mucins, and tumor metastasis. PNAS, 2001, 98, 3352-3357
    • (2001) PNAS , vol.98 , pp. 3352-3357
    • Borsig, L.1    Wong, R.2    Feramisco, J.3    Nadeau, D.R.4    Varki, N.M.5    Varki, A.6
  • 132
    • 0033391856 scopus 로고    scopus 로고
    • In vivo treatment of rats with unfractionated heparin (UFH) or low molecular weight heparin (LMWH) does not affect experimentally induced colon carcinoma metastasis
    • Smorenburg, S.M.; Vink, R.; te Lintelo, M.; Tigchelaar, W.; Maas, A.; Büller, H.R.; van Noorden, C.J. In vivo treatment of rats with unfractionated heparin (UFH) or low molecular weight heparin (LMWH) does not affect experimentally induced colon carcinoma metastasis. Clin. Exp. Metastasis, 1999, 17, 451-456
    • (1999) Clin. Exp. Metastasis , vol.17 , pp. 451-456
    • Smorenburg, S.M.1    Vink, R.2    Te Lintelo, M.3    Tigchelaar, W.4    Maas, A.5    Büller, H.R.6    Van Noorden, C.J.7
  • 133
  • 134
    • 0021871028 scopus 로고
    • Two Nacetylgalactosaminyltransferase are involved in the biosynthesis of chondroitin sulfate
    • Rohrmann, K.; Niemann, R.; Buddecke, E. Two Nacetylgalactosaminyltransferase are involved in the biosynthesis of chondroitin sulfate. Eur. J. Biochem., 1985, 148, 463-469
    • (1985) Eur. J. Biochem. , vol.148 , pp. 463-469
    • Rohrmann, K.1    Niemann, R.2    Buddecke, E.3
  • 135
    • 0029876794 scopus 로고    scopus 로고
    • Identification and partial purification of PAPS translocase
    • Ozeran, J.D.; Westley, J.; Schwartz, N.B. Identification and partial purification of PAPS translocase. Biochemistry, 1996, 35, 3695-3703
    • (1996) Biochemistry , vol.35 , pp. 3695-3703
    • Ozeran, J.D.1    Westley, J.2    Schwartz, N.B.3
  • 136
    • 0016755611 scopus 로고
    • Biosynthesis of dermatan sulfate. 1. Formation of L-iduronic acid residues
    • 1975
    • Malmstrom, A., Fransson, L.-A., Hook, M.; Lindahl, U. (1975) Biosynthesis of dermatan sulfate. 1. Formation of L-iduronic acid residues. J. Biol. Chem. 1975, 250, 3419-3425
    • (1975) J. Biol. Chem. , vol.250 , pp. 3419-3425
    • Malmstrom, A.1    Fransson, L.-A.2    Hook, M.3    Lindahl, U.4
  • 137
    • 33846247156 scopus 로고    scopus 로고
    • Chondroitin sulfate lyases: Applications in analysis and glycobiology
    • Petit, E.; Delattre, C.; Papy-Garcia, D.; Michaud, P. Chondroitin sulfate lyases: applications in analysis and glycobiology Adv. Pharmacol., 2006, 53, 167-186
    • (2006) Adv. Pharmacol. , vol.53 , pp. 167-186
    • Petit, E.1    Delattre, C.2    Papy-Garcia, D.3    Michaud, P.4
  • 140
    • 0025351937 scopus 로고
    • Altered expression of chondroitin sulfate proteoglycan in the stroma of human colon carcinoma. Hypomethylation of PG-40 gene correlates with increased PG-40 content and mRNA levels
    • Adany, R.; Heimer, R.; Caterson, B.; Sorrell, J.M.; Iozzo, R.V. Altered expression of chondroitin sulfate proteoglycan in the stroma of human colon carcinoma. Hypomethylation of PG-40 gene correlates with increased PG-40 content and mRNA levels J. Biol. Chem., 1990, 265, 11389-11396
    • (1990) J. Biol. Chem. , vol.265 , pp. 11389-11396
    • Adany, R.1    Heimer, R.2    Caterson, B.3    Sorrell, J.M.4    Iozzo, R.V.5
  • 141
    • 0037145715 scopus 로고    scopus 로고
    • Human colon adenocarcinoma is associated with specific post-translational modifications of versican and decorin
    • Theocharis, A.D. Human colon adenocarcinoma is associated with specific post-translational modifications of versican and decorin. Biochim. Biophys. Acta, 2002, 1588, 165-172
    • (2002) Biochim. Biophys. Acta , vol.1588 , pp. 165-172
    • Theocharis, A.D.1
  • 143
    • 0036163970 scopus 로고    scopus 로고
    • Neoplastic changes in saccharide sequence of dermatan sulfate chains derived from human colon cancer
    • Daidouji, K.; Takagaki, K.; Yoshihara, S.; Matsuya, H.; Sasaki, M.; Endo, M.; Neoplastic changes in saccharide sequence of dermatan sulfate chains derived from human colon cancer. Dig. Dis. Sci., 2002, 47, 331-337
    • (2002) Dig. Dis. Sci. , vol.47 , pp. 331-337
    • Daidouji, K.1    Takagaki, K.2    Yoshihara, S.3    Matsuya, H.4    Sasaki, M.5    Endo, M.6
  • 144
    • 7044247840 scopus 로고    scopus 로고
    • Versican and hyaluronan expression in canine colonic adenomas and carcinomas: Relation to malignancy and depth of tumour invasion
    • Mukaratirwa, S.; van Ederen, A.M.; Gruys, E; Nederbragt, H. Versican and hyaluronan expression in canine colonic adenomas and carcinomas: relation to malignancy and depth of tumour invasion. J. Comp. Pathol., 2004, 131, 259-270
    • (2004) J. Comp. Pathol. , vol.131 , pp. 259-270
    • Mukaratirwa, S.1    Van Ederen, A.M.2    Gruys, E.3    Nederbragt, H.4
  • 145
    • 0037180503 scopus 로고    scopus 로고
    • Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53
    • Yoon, H.; Liyanarachchi, S.; Wright, F.A.; Davuluri, R.; Lockman, J.C.; de la Chapelle, A.; Pellegata, N.S. Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53. Proc. Natl. Acad. Sci. U S A, 2002, 99, 15632-15637.
    • (2002) Proc. Natl. Acad. Sci. U S A , vol.99 , pp. 15632-15637
    • Yoon, H.1    Liyanarachchi, S.2    Wright, F.A.3    Davuluri, R.4    Lockman, J.C.5    De La Chapelle, A.6    Pellegata, N.S.7
  • 146
    • 23844507181 scopus 로고    scopus 로고
    • The role of the Wnt signaling pathway in colorectal tumorigenesis
    • Behrens, J. "The role of the Wnt signaling pathway in colorectal tumorigenesis, " Biochem Soc Trans, 2005, 33, 672-675.
    • (2005) Biochem Soc Trans , vol.33 , pp. 672-675
    • Behrens, J.1
  • 148
    • 0035861577 scopus 로고    scopus 로고
    • WISP-1 binds to decorin and biglycan
    • Desnoyers, L.; Arnott, D.; Pennica, D. WISP-1 binds to decorin and biglycan. J. Biol. Chem., 2001, 276, 47599-47607
    • (2001) J. Biol. Chem. , vol.276 , pp. 47599-47607
    • Desnoyers, L.1    Arnott, D.2    Pennica, D.3
  • 149
    • 70349868190 scopus 로고    scopus 로고
    • Presence of activating KRAS mutations correlates significantly with expression of tumour suppressor genes DCN and TPM1 in colorectal cancer
    • doi: 10.1186/1471-2407-9-282
    • Mlakar, V.; Berginc, G.; Volavsek, M.; Stor, Z.; Rems, M.; Glavac, D. Presence of activating KRAS mutations correlates significantly with expression of tumour suppressor genes DCN and TPM1 in colorectal cancer. BMC Cancer, 2009, (13), 9:282, doi: 10.1186/1471-2407-9-282
    • (2009) BMC Cancer , vol.9 , Issue.13 , pp. 282
    • Mlakar, V.1    Berginc, G.2    Volavsek, M.3    Stor, Z.4    Rems, M.5    Glavac, D.6
  • 151
    • 84863012228 scopus 로고    scopus 로고
    • Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice
    • Bi, X.; Pohl, N.M.; Qian, Z.; Yang, G.R.; Gou, Y.; Guzman, G.; Kajdacsy-Balla, A.; Iozzo, R.V.; Yang, W. Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice. Carcinogenesis, 2012, 33, 326-330
    • (2012) Carcinogenesis , vol.33 , pp. 326-330
    • Bi, X.1    Pohl, N.M.2    Qian, Z.3    Yang, G.R.4    Gou, Y.5    Guzman, G.6    Kajdacsy-Balla, A.7    Iozzo, R.V.8    Yang, W.9
  • 155
    • 84865464893 scopus 로고    scopus 로고
    • Upregulated biglycan expression correlates with the malignancy in human colorectal cancers
    • doi: 10.1007/s10238-011-0155-4 [Epub ahead of print]
    • Gu, X.; Ma, Y.; Xiao, J.; Zheng, H.; Song, C.; Gong, Y.; Xing, X. Upregulated biglycan expression correlates with the malignancy in human colorectal cancers. Clin. Exp. Med., 2011, doi: 10.1007/s10238-011-0155-4 [Epub ahead of print]
    • (2011) Clin. Exp. Med.
    • Gu, X.1    Ma, Y.2    Xiao, J.3    Zheng, H.4    Song, C.5    Gong, Y.6    Xing, X.7
  • 156
    • 0027243231 scopus 로고
    • Altered proteoglycan gene expression and the tumor stroma
    • Iozzo, R.V.; Cohen, I. Altered proteoglycan gene expression and the tumor stroma. Experientia, 1993, 49, 447-455
    • (1993) Experientia , vol.49 , pp. 447-455
    • Iozzo, R.V.1    Cohen, I.2
  • 157
    • 0037261751 scopus 로고    scopus 로고
    • Regulation of cell growth and the expression of extracellular matrix proteins in colorectal adenocarcinoma: A fibroblast-tumor cell coculture model to study tumor-host interactions in vitro
    • Hauptmann, S.; Siegert, A.; Berger, S.; Denkert, C.; Köbel, M.; Ott, S.; Siri A.; Borsi, L. Regulation of cell growth and the expression of extracellular matrix proteins in colorectal adenocarcinoma: a fibroblast-tumor cell coculture model to study tumor-host interactions in vitro. Eur J Cell Biol., 2003, 82, 1-8.
    • (2003) Eur J Cell Biol. , vol.82 , pp. 1-8
    • Hauptmann, S.1    Siegert, A.2    Berger, S.3    Denkert, C.4    Köbel, M.5    Ott, S.6    Siri, A.7    Borsi, L.8
  • 158
    • 0021839795 scopus 로고
    • Neoplastic modulation of extracellular matrix. Colon carcinoma cells release polypeptides that alter proteoglycan metabolism in colon fibroblasts
    • Iozzo RV. Neoplastic modulation of extracellular matrix. Colon carcinoma cells release polypeptides that alter proteoglycan metabolism in colon fibroblasts. J. Biol. Chem., 1985, 260, 7464-7473
    • (1985) J. Biol. Chem. , vol.260 , pp. 7464-7473
    • Iozzo, R.V.1
  • 159
    • 0025351937 scopus 로고
    • Altered expression of chondroitin sulfate proteoglycan in the stroma of human colon carcinoma. Hypomethylation of PG-40 gene correlates with increased PG-40 content and mRNA levels
    • Adany, R.; Heimer, R.; Caterson, B.; Sorrell, J.M. and Iozzo R.V. Altered expression of chondroitin sulfate proteoglycan in the stroma of human colon carcinoma. Hypomethylation of PG-40 gene correlates with increased PG-40 content and mRNA levels. J. Biol. Chem., 1990, 265, 11389-11396
    • (1990) J. Biol. Chem. , vol.265 , pp. 11389-11396
    • Adany, R.1    Heimer, R.2    Caterson, B.3    Sorrell, J.M.4    Iozzo, R.V.5
  • 164
    • 23044488163 scopus 로고    scopus 로고
    • Mutual paracrine effects of colorectal tumour cells and stromal cells: Modulation of tumour and stromal cell differentiation and extracellular matrix component production in culture
    • Mukaratirwa, S.; Koninkx, J.F.; Gruys, E.; Nederbragt, H. Mutual paracrine effects of colorectal tumour cells and stromal cells: modulation of tumour and stromal cell differentiation and extracellular matrix component production in culture. Int. J Exp. Pathol., 2005, 86, 219-229
    • (2005) Int. J Exp. Pathol. , vol.86 , pp. 219-229
    • Mukaratirwa, S.1    Koninkx, J.F.2    Gruys, E.3    Nederbragt, H.4
  • 166
    • 1642297480 scopus 로고    scopus 로고
    • Histological categorisation of fibrotic cancer stroma in advanced rectal cancer
    • Ueno, H.; Jones, A.M.; Wilkinson, K.H.; Jass, J.R.; Talbot, I.C. Histological categorisation of fibrotic cancer stroma in advanced rectal cancer. Gut, 2004, 53, 581-586
    • (2004) Gut , vol.53 , pp. 581-586
    • Ueno, H.1    Jones, A.M.2    Wilkinson, K.H.3    Jass, J.R.4    Talbot, I.C.5
  • 167
    • 0024548418 scopus 로고
    • Association between invasiveness, inflammatory reaction, desmoplasia and survival in colorectal cancer
    • Halvorsen, T.B.; Seim, E. Association between invasiveness, inflammatory reaction, desmoplasia and survival in colorectal cancer. J. Clin. Pathol, . 1989, 42, 162-166.
    • (1989) J. Clin. Pathol , vol.42 , pp. 162-166
    • Halvorsen, T.B.1    Seim, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.