-
1
-
-
0031657808
-
Matrix proteoglycans: From molecular design to cellular function
-
Iozzo,R.V. (1999) Matrix proteoglycans: From molecular design to cellular function. Annu. Rev. Biochem., 67, 609-652.
-
(1999)
Annu. Rev. Biochem
, vol.67
, pp. 609-652
-
-
Iozzo, R.V.1
-
2
-
-
0033582415
-
Decorin is a biological ligand for the epidermal growth factor receptor
-
Iozzo,R.V. et al. (1999) Decorin is a biological ligand for the epidermal growth factor receptor. J. Biol. Chem., 274, 4489-4492.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 4489-4492
-
-
Iozzo, R.V.1
-
3
-
-
0141763811
-
The role of decorin in collagen fibrillogenesis and skin homeostasis
-
Reed,C.C. et al. (2002) The role of decorin in collagen fibrillogenesis and skin homeostasis. Glycoconj. J., 19, 249-255.
-
(2002)
Glycoconj. J
, vol.19
, pp. 249-255
-
-
Reed, C.C.1
-
4
-
-
0034693263
-
Sustained down-regulation of the epidermal growth factor receptor by decorin. A mechanism for controlling tumor growth in vivo
-
Csordas,G. et al. (2000) Sustained down-regulation of the epidermal growth factor receptor by decorin. A mechanism for controlling tumor growth in vivo. J. Biol. Chem., 275, 32879-32887.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 32879-32887
-
-
Csordas, G.1
-
5
-
-
0032518407
-
Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor
-
Moscatello,D.K. et al. (1998) Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor. J. Clin. Invest. 101, 406-412.
-
(1998)
J. Clin. Invest
, vol.101
, pp. 406-412
-
-
Moscatello, D.K.1
-
6
-
-
0035798706
-
Decorin-mediated signal transduction in endothelial cells. Involvement of Akt/protein kinase B in up-regulation of p21(WAF1/CIP1) hut not p27(KIP1)
-
Schonherr,E. et al. (2001) Decorin-mediated signal transduction in endothelial cells. Involvement of Akt/protein kinase B in up-regulation of p21(WAF1/CIP1) hut not p27(KIP1). J. Biol. Chem., 276, 40687-40692.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 40687-40692
-
-
Schonherr, E.1
-
7
-
-
0344412939
-
Aberrant expression and localization of decorin in human oral dysplasia and squamous cell carcinoma
-
Banerjee,A.G. et al. (2003) Aberrant expression and localization of decorin in human oral dysplasia and squamous cell carcinoma. Cancer Res., 63, 7769-7776.
-
(2003)
Cancer Res
, vol.63
, pp. 7769-7776
-
-
Banerjee, A.G.1
-
8
-
-
0037161919
-
Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin
-
Reed,C.C. et al. (2002) Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin. Oncogene, 21, 3688-3695.
-
(2002)
Oncogene
, vol.21
, pp. 3688-3695
-
-
Reed, C.C.1
-
9
-
-
33644868712
-
Transforming growth factor-beta: A molecular target for ihe future therapy of glioblastoma
-
Wick,W. et al. (2006) Transforming growth factor-beta: A molecular target for ihe future therapy of glioblastoma. Curr. Pharm. Des., 12, 341-349.
-
(2006)
Curr. Pharm. Des
, vol.12
, pp. 341-349
-
-
Wick, W.1
-
10
-
-
0029088680
-
De novo decorin gene expression suppresses the malignant phenotype in human colon cancer cells
-
Santra,M. et al. (1995) De novo decorin gene expression suppresses the malignant phenotype in human colon cancer cells. Proc. Natl Acad. Sci. USA, 92, 7016-7020.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 7016-7020
-
-
Santra, M.1
-
11
-
-
0029785662
-
Decorin-induced growth suppression is associated with up-regulation of p21, an inhibitor of cyclin-dependent kinases
-
De Luca,A. et al. (1996) Decorin-induced growth suppression is associated with up-regulation of p21, an inhibitor of cyclin-dependent kinases. J. Biol. Chem., 271, 18961-18965.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 18961-18965
-
-
De Luca, A.1
-
12
-
-
13944249920
-
Decorin prevents metastatic spreading of breast cancer
-
Reed,C.C. et al. (2005) Decorin prevents metastatic spreading of breast cancer. Oncogene, 24, 1104-1110.
-
(2005)
Oncogene
, vol.24
, pp. 1104-1110
-
-
Reed, C.C.1
-
13
-
-
0031044872
-
Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility
-
Danielson, K.G. et al. (1997) Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility. J. Cell Biol., 136, 729-743.
-
(1997)
J. Cell Biol
, vol.136
, pp. 729-743
-
-
Danielson, K.G.1
-
14
-
-
34547653108
-
c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression
-
Tong,C. et al. (2007) c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression. Am. J. Pathol. 171, 297-303.
-
(2007)
Am. J. Pathol
, vol.171
, pp. 297-303
-
-
Tong, C.1
-
15
-
-
0035863515
-
Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal
-
Yang,W. et al. (2001) Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal. Cancer Res., 61, 565-569.
-
(2001)
Cancer Res
, vol.61
, pp. 565-569
-
-
Yang, W.1
-
16
-
-
0042941403
-
Targeted inactivation of p27kip1 is sufficient for large and small intestinal tumorigenesis in the mouse, which can be augmented by a Western-style high-risk diet
-
Yang,W. et al. (2003) Targeted inactivation of p27kip1 is sufficient for large and small intestinal tumorigenesis in the mouse, which can be augmented by a Western-style high-risk diet. Cancer Res. 63, 4990-4996.
-
(2003)
Cancer Res
, vol.63
, pp. 4990-4996
-
-
Yang, W.1
-
17
-
-
0028567875
-
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors
-
Fodde,R. et al. (1994) A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proc. Natl Acad Sci. USA, 91, 8969-8973.
-
(1994)
Proc. Natl Acad Sci. USA
, vol.91
, pp. 8969-8973
-
-
Fodde, R.1
-
18
-
-
27144529070
-
p27kip1 in intestinal tumorigenesis and chemoprevention in the mouse
-
Yang,W. et al. (2005) p27kip1 in intestinal tumorigenesis and chemoprevention in the mouse. Cancer Res., 65, 9363-9368.
-
(2005)
Cancer Res
, vol.65
, pp. 9363-9368
-
-
Yang, W.1
-
19
-
-
0035169454
-
A Western-style diet induces benign and malignant neoplasms in the colon of normal C57B1/6 mice
-
Newmark,H.L. et al. (2001) A Western-style diet induces benign and malignant neoplasms in the colon of normal C57B1/6 mice. Carcinogenesis, 22, 1871-1875.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1871-1875
-
-
Newmark, H.L.1
-
20
-
-
33745177351
-
Regulation of mucin expression: Mechanistic aspects and implications for cancer and inflammatory diseases
-
Andrianifahanana,M. et al. (2006) Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseases. Biochim. Biophys. Acta, 1765, 189-222.
-
(2006)
Biochim. Biophys. Acta
, vol.1765
, pp. 189-222
-
-
Andrianifahanana, M.1
-
21
-
-
0036500996
-
Colorectal cancer in mice genetically deficient in the mucin Muc2
-
Velcich,A. et al. (2002) Colorectal cancer in mice genetically deficient in the mucin Muc2. Science, 295, 1726-1729.
-
(2002)
Science
, vol.295
, pp. 1726-1729
-
-
Velcich, A.1
-
22
-
-
0033046972
-
Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis
-
Iozzo,R.V. et al. (1999) Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis. Proc. Natl Acad. Sci. USA, 96, 3092-3097.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 3092-3097
-
-
Iozzo, R.V.1
-
23
-
-
0027496935
-
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
Harper,J.W. et al. (1993) The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell, 75, 805-816.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
-
24
-
-
0028981086
-
Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues
-
el-Deiry,W.S. et al. (1995) Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. Cancer Res., 95 2910-2919.
-
(1995)
Cancer Res
, vol.95
, pp. 2910-2919
-
-
el-Deiry, W.S.1
-
25
-
-
0030057835
-
Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia
-
Polyak,K. et al. (1996) Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia. Am. J. Pathol., 149 381-387.
-
(1996)
Am. J. Pathol
, vol.149
, pp. 381-387
-
-
Polyak, K.1
-
26
-
-
0033572612
-
In vitro growth inhibition of ovarian cancer cells by decorin: Synergism of action between decorin and carboplatin
-
Nash,M.A. et al. (1999) In vitro growth inhibition of ovarian cancer cells by decorin: Synergism of action between decorin and carboplatin. Cancer Res., 59, 6192-6196.
-
(1999)
Cancer Res
, vol.59
, pp. 6192-6196
-
-
Nash, M.A.1
-
27
-
-
0030798869
-
Isotopic expression of decorin protein core causes a generalized growth suppression in nepplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases
-
Santa,M. et al. (1997) Isotopic expression of decorin protein core causes a generalized growth suppression in nepplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases. J. Clin. Invest., 100, 149-157.
-
(1997)
J. Clin. Invest
, vol.100
, pp. 149-157
-
-
Santa, M.1
-
28
-
-
0035496907
-
Decorin inhibits macrophage colony-stimulating factor proliferition of macrophages and enhances cell survival through induction of p27 (Kip1) and p21(Waf1)
-
Xaus,J. et al. (2001) Decorin inhibits macrophage colony-stimulating factor proliferition of macrophages and enhances cell survival through induction of p27 (Kip1) and p21(Waf1). Blood, 98, 2124-2133.
-
(2001)
Blood
, vol.98
, pp. 2124-2133
-
-
Xaus, J.1
-
29
-
-
17144374133
-
Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice
-
Yang,W. et al. (2005) Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice. Am. J. Pathol., 166 1239-1246.
-
(2005)
Am. J. Pathol
, vol.166
, pp. 1239-1246
-
-
Yang, W.1
-
30
-
-
0030938715
-
Organization and regulatory aspects of the human intestinal mucin gene (MUC2) locus
-
Velcich,A. et al. (1997) Organization and regulatory aspects of the human intestinal mucin gene (MUC2) locus. J. Biol. Chem., 272, 7968-7976.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 7968-7976
-
-
Velcich, A.1
-
31
-
-
0344076341
-
-
van Minken,B.J. et al. (1999) Gastrointestinal expression and partial cDNA cloning of murine Muc:2. Am. J. Physiol., 276, G115-G124.
-
van Minken,B.J. et al. (1999) Gastrointestinal expression and partial cDNA cloning of murine Muc:2. Am. J. Physiol., 276, G115-G124.
-
-
-
-
32
-
-
0033564697
-
CDK inhibitors: Positive and negative regulators of G1-phase progression
-
Sherr,C.J. et al. (1999) CDK inhibitors: Positive and negative regulators of G1-phase progression. Genes Dev., 13, 1501-1512.
-
(1999)
Genes Dev
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
-
33
-
-
0032444464
-
Prognostic implications of expression of the cell cycle inhibitor protein p27Kip1
-
Cariou,S. et al. (1998) Prognostic implications of expression of the cell cycle inhibitor protein p27Kip1. Breast Cancer Res. Treat. 52, 29-41.
-
(1998)
Breast Cancer Res. Treat
, vol.52
, pp. 29-41
-
-
Cariou, S.1
-
34
-
-
0035121553
-
Role of p27(Kip1) in human intestinal cell differentiation
-
Deschenes,C. et al. (2001) Role of p27(Kip1) in human intestinal cell differentiation. Gastroenterology, 120, 423-438.
-
(2001)
Gastroenterology
, vol.120
, pp. 423-438
-
-
Deschenes, C.1
-
35
-
-
0032587495
-
p27kip1: A multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers
-
Lloyd,R.V. et al. (1999) p27kip1: A multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers. Am. J. Pathol., 154, 313-323.
-
(1999)
Am. J. Pathol
, vol.154
, pp. 313-323
-
-
Lloyd, R.V.1
-
36
-
-
0031689717
-
Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases
-
Thomas,G.V. et al. (1998) Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases. Am. J. Pathol., 153, 681-687.
-
(1998)
Am. J. Pathol
, vol.153
, pp. 681-687
-
-
Thomas, G.V.1
-
37
-
-
0032980308
-
The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer
-
Tsihlias,J. et al. (1999) The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer. Annu. Rev. Med. 50, 401-423.
-
(1999)
Annu. Rev. Med
, vol.50
, pp. 401-423
-
-
Tsihlias, J.1
-
38
-
-
0033918737
-
Down-regulation of p27 is a significant predictor of poor overall survival and may facilitate metastasis in colorectal carcinomas
-
Yao,J. et al. (2000) Down-regulation of p27 is a significant predictor of poor overall survival and may facilitate metastasis in colorectal carcinomas. Int. J. Cancer, 89, 213-216.
-
(2000)
Int. J. Cancer
, vol.89
, pp. 213-216
-
-
Yao, J.1
-
39
-
-
0035407504
-
Loss of p27 expression predicts poor prognosis in patients with Dukes' B stage or proximal colorectal cancer
-
Zhang,H. et al. (2001) Loss of p27 expression predicts poor prognosis in patients with Dukes' B stage or proximal colorectal cancer. Int. J. Oncol., 19, 49-52.
-
(2001)
Int. J. Oncol
, vol.19
, pp. 49-52
-
-
Zhang, H.1
-
40
-
-
18644373146
-
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
-
van de Wetering,M. et al. (2002) The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 111, 241-250.
-
(2002)
Cell
, vol.111
, pp. 241-250
-
-
van de Wetering, M.1
-
41
-
-
8444251784
-
The Wnt signaling pathway in development and disease
-
Logan,C.Y. et al. (2004) The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol., 20, 781-810.
-
(2004)
Annu. Rev. Cell Dev. Biol
, vol.20
, pp. 781-810
-
-
Logan, C.Y.1
-
42
-
-
0141651204
-
Cadherins as modulators of cellular phenotype
-
Wheelock,M.J. et al. (2003) Cadherins as modulators of cellular phenotype. Annu. Rev. Cell Dev. Biol., 19, 207-235.
-
(2003)
Annu. Rev. Cell Dev. Biol
, vol.19
, pp. 207-235
-
-
Wheelock, M.J.1
|