메뉴 건너뛰기




Volumn 3 MAR, Issue , 2012, Pages

Aspects of innate immunity and Parkinson's disease

Author keywords

Immunity; Mitochondrial dysfunction; Parkinson's disease; Synapse dysfunction; Ubiquitination

Indexed keywords

ALPHA SYNUCLEIN; ATM PROTEIN; DJ 1 PROTEIN; HISTONE DEACETYLASE; HLA DR ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUCINE RICH REPEAT KINASE 2; PARKIN; SERINE PROTEINASE OMI; SNARE PROTEIN; UBIQUITIN THIOLESTERASE;

EID: 84865967984     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2012.00033     Document Type: Article
Times cited : (17)

References (111)
  • 2
    • 70350362348 scopus 로고    scopus 로고
    • Alpha-synuclein inhibits poly (ADP-ribose) polymerase-1 (PARP-1) activity via NO-dependent pathway
    • Adamczyk, A., and Kazmierczak, A. (2009). Alpha-synuclein inhibits poly (ADP-ribose) polymerase-1 (PARP-1) activity via NO-dependent pathway. Folia Neuropathol. 47, 247-251.
    • (2009) Folia Neuropathol , vol.47 , pp. 247-251
    • Adamczyk, A.1    Kazmierczak, A.2
  • 3
    • 79251543343 scopus 로고    scopus 로고
    • Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice
    • doi:10.1371/journal.pone. 0016038
    • Akundi, R. S., Huang, Z., Eason, J., Pandya, J. D., Zhi, L., Cass, W. A., Sullivan, P. G., and Bueler, H. (2011). Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice. PLoS ONE 6, e16038. doi:10.1371/journal.pone. 0016038
    • (2011) PLoS ONE , vol.6
    • Akundi, R.S.1    Huang, Z.2    Eason, J.3    Pandya, J.D.4    Zhi, L.5    Cass, W.A.6    Sullivan, P.G.7    Bueler, H.8
  • 4
    • 2342580076 scopus 로고    scopus 로고
    • The RNA binding protein Sam68 is acetylated in tumor cell lines, and its acetylation correlates with enhanced RNA binding activity
    • Babic, I., Jakymiw, A., and Fujita, D. J. (2004). The RNA binding protein Sam68 is acetylated in tumor cell lines, and its acetylation correlates with enhanced RNA binding activity. Oncogene 23, 3781-3789.
    • (2004) Oncogene , vol.23 , pp. 3781-3789
    • Babic, I.1    Jakymiw, A.2    Fujita, D.J.3
  • 7
    • 0023337475 scopus 로고
    • Cigarette smoking Parkinson's disease and ulcerative colitis
    • Bihari, K., and Lees, A. J. (1987). Cigarette smoking, Parkinson's disease and ulcerative colitis. J. Neurol. Neurosurg. Psychiatr. 50, 635.
    • (1987) J. Neurol. Neurosurg. Psychiatr. , vol.50 , pp. 635
    • Bihari, K.1    Lees, A.J.2
  • 8
    • 2942635265 scopus 로고    scopus 로고
    • Microarray expression analysis of gad mice implicates involvement of Parkinson's disease associated UCHL1 in multiple metabolic pathways
    • Bonin, M., Poths, S., Osaka, H., Wang, Y. L., Wada, K., and Riess, O. (2004). Microarray expression analysis of gad mice implicates involvement of Parkinson's disease associated UCHL1 in multiple metabolic pathways. Brain Res. Mol. Brain Res. 126,88-97.
    • (2004) Brain Res. Mol Brain Res. , vol.126 , pp. 88-97
    • Bonin, M.1    Poths, S.2    Osaka, H.3    Wang, Y.L.4    Wada, K.5    Riess, O.6
  • 9
    • 0038748401 scopus 로고    scopus 로고
    • Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen
    • Braak, H., Rub, U., Gai, W. P., and Del Tredici, K. (2003). Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen. J. Neural Transm. 110, 517-536.
    • (2003) J. Neural Transm , vol.110 , pp. 517-536
    • Braak, H.1    Rub, U.2    Gai, W.P.3    Del Tredici, K.4
  • 11
    • 79956078781 scopus 로고    scopus 로고
    • Leprosy susceptibility: genetic variations regulate innate and adaptive immunity, and disease outcome
    • Cardoso, C. C., Pereira, A. C., De Sales Marques, C., and Moraes, M. O. (2011). Leprosy susceptibility: genetic variations regulate innate and adaptive immunity, and disease outcome. Future Microbiol. 6, 533-549.
    • (2011) Future Microbiol , vol.6 , pp. 533-549
    • Cardoso, C.C.1    Pereira, A.C.2    De Sales Marques, C.3    Moraes, M.O.4
  • 13
    • 4344691112 scopus 로고    scopus 로고
    • Prenatal exposure to the bacteriotoxin lipopolysaccharide leads to longterm losses of dopamine neurons in offspring: a potential, new model of Parkinson's disease
    • Carvey, P. M., Chang, Q., Lipton, J. W., and Ling, Z. (2003). Prenatal exposure to the bacteriotoxin lipopolysaccharide leads to longterm losses of dopamine neurons in offspring: a potential, new model of Parkinson's disease. Front. Biosci. 8, s826-s837.
    • (2003) Front. Biosci. , vol.8
    • Carvey, P.M.1    Chang, Q.2    Lipton, J.W.3    Ling, Z.4
  • 15
    • 27544507306 scopus 로고    scopus 로고
    • Alphasynuclein cooperates with CSPalpha in preventing neurodegeneration
    • Chandra, S., Gallardo, G., Fernandez-Chacon, R., Schluter, O. M., and Sudhof, T. C. (2005). Alphasynuclein cooperates with CSPalpha in preventing neurodegeneration. Cell 123, 383-396.
    • (2005) Cell , vol.123 , pp. 383-396
    • Chandra, S.1    Gallardo, G.2    Fernandez-Chacon, R.3    Schluter, O.M.4    Sudhof, T.C.5
  • 16
    • 23144449789 scopus 로고    scopus 로고
    • Ubiquitin signalling in the NF-kappaB pathway
    • Chen, Z. J. (2005). Ubiquitin signalling in the NF-kappaB pathway. Nat. Cell Biol. 7, 758-765.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 758-765
    • Chen, Z.J.1
  • 17
    • 13844289143 scopus 로고    scopus 로고
    • Regulation of alphasynuclein expression by poly (ADP ribose) polymerase-1 (PARP-1) binding to the NACP-Rep1 polymorphic site upstream of the SNCA gene
    • Chiba-Falek, O., Kowalak, J. A., Smulson, M. E., and Nussbaum, R. L. (2005). Regulation of alphasynuclein expression by poly (ADP ribose) polymerase-1 (PARP-1) binding to the NACP-Rep1 polymorphic site upstream of the SNCA gene. Am. J. Hum. Genet. 76, 478-492.
    • (2005) Am. J. Hum. Genet. , vol.76 , pp. 478-492
    • Chiba-Falek, O.1    Kowalak, J.A.2    Smulson, M.E.3    Nussbaum, R.L.4
  • 19
    • 80054787664 scopus 로고    scopus 로고
    • What genetics tells us about the causes and mechanisms of Parkinson's disease
    • Corti, O., Lesage, S., and Brice, A. (2011). What genetics tells us about the causes and mechanisms of Parkinson's disease. Physiol. Rev. 91, 1161-1218.
    • (2011) Physiol. Rev. , vol.91 , pp. 1161-1218
    • Corti, O.1    Lesage, S.2    Brice, A.3
  • 22
    • 78649745833 scopus 로고    scopus 로고
    • The Toll-like receptor3 agonist polyinosinic:polycytidylic acid triggers nigrostriatal dopaminergic degeneration
    • Deleidi, M., Hallett, P. J., Koprich, J. B., Chung, C. Y., and Isacson, O. (2010). The Toll-like receptor3 agonist polyinosinic:polycytidylic acid triggers nigrostriatal dopaminergic degeneration. J. Neurosci. 30, 16091-16101.
    • (2010) J. Neurosci , vol.30 , pp. 16091-16101
    • Deleidi, M.1    Hallett, P.J.2    Koprich, J.B.3    Chung, C.Y.4    Isacson, O.5
  • 24
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • Diebold, S. S., Kaisho, T., Hemmi, H., Akira,S.,and Reis E Sousa,C. (2004). Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303, 1529-1531.
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reis, E.5    Sousa, C.6
  • 25
    • 20444450523 scopus 로고    scopus 로고
    • Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains
    • Doss-Pepe, E. W., Chen, L., and Madura, K. (2005). Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains. J. Biol. Chem. 280, 16619-16624.
    • (2005) J. Biol. Chem. , vol.280 , pp. 16619-16624
    • Doss-Pepe, E.W.1    Chen, L.2    Madura, K.3
  • 26
    • 52449115580 scopus 로고    scopus 로고
    • The lipopolysaccharide Parkinson's disease animal model: mechanistic studies and drug discovery
    • Dutta, G., Zhang, P., and Liu, B. (2008). The lipopolysaccharide Parkinson's disease animal model: mechanistic studies and drug discovery. Fundam. Clin. Pharmacol. 22, 453-464.
    • (2008) Fundam. Clin. Pharmacol. , vol.22 , pp. 453-464
    • Dutta, G.1    Zhang, P.2    Liu, B.3
  • 28
    • 79955501079 scopus 로고    scopus 로고
    • Postencephalitic parkinsonism and basal ganglia necrosis due to Epstein-Barr virus infection
    • Espay, A. J., and Henderson, K. K. (2011). Postencephalitic parkinsonism and basal ganglia necrosis due to Epstein-Barr virus infection. Neurology 76, 1529-1530.
    • (2011) Neurology , vol.76 , pp. 1529-1530
    • Espay, A.J.1    Henderson, K.K.2
  • 29
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: substantia nigra regional selectivity
    • Fearnley, J. M., and Lees, A. J. (1991). Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114 (Pt 5), 2283-2301.
    • (1991) Brain , vol.114 , Issue.PART 5 , pp. 2283-2301
    • Fearnley, J.M.1    Lees, A.J.2
  • 30
    • 67349128592 scopus 로고    scopus 로고
    • Early involvement of the cerebral cortex in Parkinson's disease: convergence of multiple metabolic defects
    • Ferrer, I. (2009). Early involvement of the cerebral cortex in Parkinson's disease: convergence of multiple metabolic defects. Prog. Neurobiol. 88, 89-103.
    • (2009) Prog. Neurobiol. , vol.88 , pp. 89-103
    • Ferrer, I.1
  • 36
    • 33749249590 scopus 로고    scopus 로고
    • NF-kappaB activation by doublestrand breaks
    • Habraken, Y., and Piette, J. (2006). NF-kappaB activation by doublestrand breaks. Biochem. Pharmacol. 72, 1132-1141.
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 1132-1141
    • Habraken, Y.1    Piette, J.2
  • 37
    • 0032476602 scopus 로고    scopus 로고
    • CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation
    • Hacker, H., Mischak, H., Miethke, T., Liptay, S., Schmid, R., Sparwasser, T., Heeg, K., Lipford, G. B., and Wagner, H. (1998). CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. EMBO J. 17, 6230-6240.
    • (1998) EMBO J , vol.17 , pp. 6230-6240
    • Hacker, H.1    Mischak, H.2    Miethke, T.3    Liptay, S.4    Schmid, R.5    Sparwasser, T.6    Heeg, K.7    Lipford, G.B.8    Wagner, H.9
  • 38
    • 78751554067 scopus 로고    scopus 로고
    • Signals from the nucleus: activation of NF-kappaB by cytosolic ATM in the DNA damage response
    • Hadian, K., and Krappmann, D. (2011). Signals from the nucleus: activation of NF-kappaB by cytosolic ATM in the DNA damage response. Sci. Signal. 4, pe2.
    • (2011) Sci. Signal. , vol.4
    • Hadian, K.1    Krappmann, D.2
  • 39
    • 79951499176 scopus 로고    scopus 로고
    • Glia: initiators and progressors of pathology in Parkinson's disease
    • Halliday, G. M., and Stevens, C. H. (2011). Glia: initiators and progressors of pathology in Parkinson's disease. Mov. Disord. 26, 6-17.
    • (2011) Mov. Disord. , vol.26 , pp. 6-17
    • Halliday, G.M.1    Stevens, C.H.2
  • 42
    • 0035796025 scopus 로고    scopus 로고
    • Functions of poly (ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death
    • Herceg, Z., and Wang, Z. Q. (2001). Functions of poly (ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death. Mutat. Res. 477, 97-110.
    • (2001) Mutat. Res. , vol.477 , pp. 97-110
    • Herceg, Z.1    Wang, Z.Q.2
  • 43
    • 80655141577 scopus 로고    scopus 로고
    • Evidence for more than one Parkinson's disease-associated variant within the HLA region
    • doi:10.1371/journal.pone.0027109
    • Hill-Burns, E. M., Factor, S. A., Zabetian, C. P., Thomson, G., and Payami, H. (2011). Evidence for more than one Parkinson's disease-associated variant within the HLA region. PLoS ONE 6, e27109. doi:10.1371/journal.pone.0027109
    • (2011) PLoS ONE , vol.6
    • Hill-Burns, E.M.1    Factor, S.A.2    Zabetian, C.P.3    Thomson, G.4    Payami, H.5
  • 44
    • 77957333810 scopus 로고    scopus 로고
    • A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-kappaB activation
    • Hinz, M., Stilmann, M., Arslan, S. C., Khanna, K. K., Dittmar, G., and Scheidereit, C. (2010). A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-kappaB activation. Mol. Cell 40, 63-74.
    • (2010) Mol. Cell , vol.40 , pp. 63-74
    • Hinz, M.1    Stilmann, M.2    Arslan, S.C.3    Khanna, K.K.4    Dittmar, G.5    Scheidereit, C.6
  • 46
    • 0141995596 scopus 로고    scopus 로고
    • The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI
    • Huynh, D. P., Scoles, D. R., Nguyen, D., and Pulst, S. M. (2003). The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI. Hum. Mol. Genet. 12, 2587-2597.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 2587-2597
    • Huynh, D.P.1    Scoles, D.R.2    Nguyen, D.3    Pulst, S.M.4
  • 47
    • 44649101850 scopus 로고    scopus 로고
    • Atypical ubiquitin chains: new molecular signals " Protein Modifications: Beyond the Usual Suspects" review series
    • Ikeda, F., and Dikic, I. (2008). Atypical ubiquitin chains: new molecular signals. " Protein Modifications: Beyond the Usual Suspects" review series. EMBO Rep. 9, 536-542.
    • (2008) EMBO Rep , vol.9 , pp. 536-542
    • Ikeda, F.1    Dikic, I.2
  • 48
    • 78149233131 scopus 로고    scopus 로고
    • Regulation of MyD88 aggregation and the MyD88-dependent signaling pathway by sequestosome 1 and histone deacetylase 6
    • Into, T., Inomata, M., Niida, S., Murakami, Y., and Shibata, K. (2010). Regulation of MyD88 aggregation and the MyD88-dependent signaling pathway by sequestosome 1 and histone deacetylase 6. J. Biol. Chem. 285, 35759-35769.
    • (2010) J. Biol. Chem. , vol.285 , pp. 35759-35769
    • Into, T.1    Inomata, M.2    Niida, S.3    Murakami, Y.4    Shibata, K.5
  • 49
    • 0028985267 scopus 로고
    • The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system
    • Iwai, A., Masliah, E., Yoshimoto, M., Ge, N., Flanagan, L., De Silva, H. A., Kittel,A., and Saitoh, T. (1995). The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system. Neuron 14, 467-475.
    • (1995) Neuron , vol.14 , pp. 467-475
    • Iwai, A.1    Masliah, E.2    Yoshimoto, M.3    Ge, N.4    Flanagan, L.5    De Silva, H.A.6    Kittel, A.7    Saitoh, T.8
  • 50
    • 34247127355 scopus 로고    scopus 로고
    • The role of poly (ADPribose) polymerase-1 in CNS disease
    • Kauppinen, T. M., and Swanson, R. A. (2007). The role of poly (ADPribose) polymerase-1 in CNS disease. Neuroscience 145, 1267-1272.
    • (2007) Neuroscience , vol.145 , pp. 1267-1272
    • Kauppinen, T.M.1    Swanson, R.A.2
  • 51
    • 31344461659 scopus 로고    scopus 로고
    • Innate immune recognition of viral infection
    • Kawai, T., and Akira, S. (2006). Innate immune recognition of viral infection. Nat. Immunol. 7, 131-137.
    • (2006) Nat. Immunol. , vol.7 , pp. 131-137
    • Kawai, T.1    Akira, S.2
  • 54
    • 84861336468 scopus 로고    scopus 로고
    • Genome-wide expression profiling implicates a MAST3regulated gene set in colonic mucosal inflammation of ulcerative colitis patients
    • doi: 10.1002/ibd.21887. [Epub ahead of print]
    • Labbe, C., Boucher, G., Foisy, S., Alikashani, A., Nkwimi, H., David, G., Beaudoin, M., Goyette, P., Charron, G., Xavier, R. J., and Rioux, J. D. (2011). Genome-wide expression profiling implicates a MAST3regulated gene set in colonic mucosal inflammation of ulcerative colitis patients. Inflamm. Bowel Dis. doi: 10.1002/ibd.21887. [Epub ahead of print].
    • (2011) Inflamm. Bowel Dis.
    • Labbe, C.1    Boucher, G.2    Foisy, S.3    Alikashani, A.4    Nkwimi, H.5    David, G.6    Beaudoin, M.7    Goyette, P.8    Charron, G.9    Xavier, R.J.10    Rioux, J.D.11
  • 55
    • 0021239393 scopus 로고
    • Parkinsonism induced by 1-methyl-4-phenyl-1,2,3 6tetrahydropyridine (MPTP): implications for treatment and the pathogenesis of Parkinson's disease
    • Langston, J. W., and Ballard, P. (1984). Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6tetrahydropyridine (MPTP): implications for treatment and the pathogenesis of Parkinson's disease. Can. J. Neurol. Sci. 11, 160-165.
    • (1984) Can. J. Neurol. Sci. , vol.11 , pp. 160-165
    • Langston, J.W.1    Ballard, P.2
  • 57
    • 0036902707 scopus 로고    scopus 로고
    • Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress
    • Ledesma, M. D., Galvan, C., Hellias, B., Dotti, C., and Jensen, P. H. (2002). Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress. J. Neurochem. 83, 1431-1440.
    • (2002) J. Neurochem. , vol.83 , pp. 1431-1440
    • Ledesma, M.D.1    Galvan, C.2    Hellias, B.3    Dotti, C.4    Jensen, P.H.5
  • 58
    • 33746065340 scopus 로고    scopus 로고
    • Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity
    • Leng, Y., and Chuang, D. M. (2006). Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity. J. Neurosci. 26, 7502-7512.
    • (2006) J. Neurosci. , vol.26 , pp. 7502-7512
    • Leng, Y.1    Chuang, D.M.2
  • 60
    • 0036460861 scopus 로고    scopus 로고
    • utero bacterial endotoxin exposure causes loss of tyrosine hydroxylase neurons in the postnatal rat midbrain
    • Ling, Z., Gayle, D. A., Ma, S. Y., Lipton, J. W., Tong, C. W., Hong, J. S., and Carvey,P. M. (2002). In utero bacterial endotoxin exposure causes loss of tyrosine hydroxylase neurons in the postnatal rat midbrain. Mov. Disord. 17, 116-124.
    • (2002) Mov. Disord. , vol.17 , pp. 116-124
    • Ling, Z.1    Gayle, D.A.2    Ma, S.Y.3    Lipton, J.W.4    Tong, C.W.5    Hong, J.S.6    Carvey, P.M.7
  • 61
    • 33749556982 scopus 로고    scopus 로고
    • Modulation of microglial pro-inflammatory and neurotoxic activity for the treatment of Parkinson's disease
    • Liu, B. (2006). Modulation of microglial pro-inflammatory and neurotoxic activity for the treatment of Parkinson's disease. AAPS J. 8, E606-E621.
    • (2006) AAPS J , vol.8
    • Liu, B.1
  • 62
    • 0037131567 scopus 로고    scopus 로고
    • The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility
    • Liu, Y., Fallon, L., Lashuel, H. A., Liu, Z., and Lansbury, P. T. Jr. (2002). The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. Cell 111, 209-218.
    • (2002) Cell , vol.111 , pp. 209-218
    • Liu, Y.1    Fallon, L.2    Lashuel, H.A.3    Liu, Z.4    Lansbury Jr., P.T.5
  • 64
    • 0023789193 scopus 로고
    • Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
    • McGeer, P. L., Itagaki, S., Boyes, B. E., and McGeer, E. G. (1988). Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 38, 1285-1291.
    • (1988) Neurology , vol.38 , pp. 1285-1291
    • McGeer, P.L.1    Itagaki, S.2    Boyes, B.E.3    McGeer, E.G.4
  • 66
    • 30444443297 scopus 로고    scopus 로고
    • Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys
    • Miklossy, J., Doudet, D. D., Schwab, C., Yu, S.,Mcgeer, E. G., and Mcgeer, P. L. (2006). Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys. Exp. Neurol. 197, 275-283.
    • (2006) Exp. Neurol. , vol.197 , pp. 275-283
    • Miklossy, J.1    Doudet, D.D.2    Schwab, C.3    Yu, S.4    Mcgeer, E.G.5    Mcgeer, P.L.6
  • 67
    • 0032738677 scopus 로고    scopus 로고
    • The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease
    • Mirza, B., Hadberg, H., Thomsen, P., and Moos, T. (2000). The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease. Neuroscience 95, 425-432.
    • (2000) Neuroscience , vol.95 , pp. 425-432
    • Mirza, B.1    Hadberg, H.2    Thomsen, P.3    Moos, T.4
  • 68
    • 33646411492 scopus 로고    scopus 로고
    • Mitochondria in Parkinson disease: back in fashion with a little help from genetics
    • Muqit, M. M., Gandhi, S., and Wood, N. W. (2006). Mitochondria in Parkinson disease: back in fashion with a little help from genetics. Arch. Neurol. 63, 649-654.
    • (2006) Arch. Neurol. , vol.63 , pp. 649-654
    • Muqit, M.M.1    Gandhi, S.2    Wood, N.W.3
  • 70
    • 0036518997 scopus 로고    scopus 로고
    • Innate immunity: the missing link in neuroprotection and neurodegeneration?
    • Nguyen, M. D., Julien, J. P., and Rivest, S. (2002). Innate immunity: the missing link in neuroprotection and neurodegeneration? Nat. Rev. Neurosci. 3, 216-227.
    • (2002) Nat Rev. Neurosci. , vol.3 , pp. 216-227
    • Nguyen, M.D.1    Julien, J.P.2    Rivest, S.3
  • 71
    • 0344304443 scopus 로고    scopus 로고
    • Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and histone deacetylase 1
    • Nusinzon, I., and Horvath, C. M. (2003). Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and histone deacetylase 1. Proc. Natl. Acad. Sci. U.S.A. 100, 14742-14747.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 14742-14747
    • Nusinzon, I.1    Horvath, C.M.2
  • 72
    • 0036935553 scopus 로고    scopus 로고
    • An inflammatory review of Parkinson's disease
    • Orr, C. F., Rowe, D. B., and Halliday, G. M. (2002). An inflammatory review of Parkinson's disease. Prog. Neurobiol. 68, 325-340.
    • (2002) Prog. Neurobiol. , vol.68 , pp. 325-340
    • Orr, C.F.1    Rowe, D.B.2    Halliday, G.M.3
  • 73
    • 27644531857 scopus 로고    scopus 로고
    • A possible role for humoral immunity in the pathogenesis of Parkinson's disease
    • Orr, C. F., Rowe, D. B., Mizuno,Y., Mori, H., and Halliday, G. M. (2005). A possible role for humoral immunity in the pathogenesis of Parkinson's disease. Brain 128, 2665-2674.
    • (2005) Brain , vol.128 , pp. 2665-2674
    • Orr, C.F.1    Rowe, D.B.2    Mizuno, Y.3    Mori, H.4    Halliday, G.M.5
  • 75
    • 3242710339 scopus 로고    scopus 로고
    • The influence of systemic inflammation on inflammation in the brain: implications for chronic neurodegenerative disease
    • Perry, V. H. (2004). The influence of systemic inflammation on inflammation in the brain: implications for chronic neurodegenerative disease. Brain Behav. Immun. 18, 407-413.
    • (2004) Brain Behav. Immun. , vol.18 , pp. 407-413
    • Perry, V.H.1
  • 79
    • 0035070697 scopus 로고    scopus 로고
    • Regulation of proteasome complexes by gamma-interferon and phosphorylation
    • Rivett, A. J., Bose, S., Brooks, P., and Broadfoot, K. I. (2001). Regulation of proteasome complexes by gamma-interferon and phosphorylation. Biochimie 83, 363-366.
    • (2001) Biochimie , vol.83 , pp. 363-366
    • Rivett, A.J.1    Bose, S.2    Brooks, P.3    Broadfoot, K.I.4
  • 80
    • 34447554529 scopus 로고    scopus 로고
    • Starring roles for astroglia in barrier pathologies of gut and brain
    • Savidge, T. C., Sofroniew, M. V., and Neunlist, M. (2007). Starring roles for astroglia in barrier pathologies of gut and brain. Lab. Invest. 87, 731-736.
    • (2007) Lab. Invest. , vol.87 , pp. 731-736
    • Savidge, T.C.1    Sofroniew, M.V.2    Neunlist, M.3
  • 83
    • 27844507557 scopus 로고    scopus 로고
    • Double-stranded RNA signals antiviral and inflammatory programs and dysfunctional glutamate transport in TLR3-expressing astrocytes
    • Scumpia, P. O., Kelly, K. M., Reeves, W. H., and Stevens, B. R. (2005). Double-stranded RNA signals antiviral and inflammatory programs and dysfunctional glutamate transport in TLR3-expressing astrocytes. Glia 52, 153-162.
    • (2005) Glia , vol.52 , pp. 153-162
    • Scumpia, P.O.1    Kelly, K.M.2    Reeves, W.H.3    Stevens, B.R.4
  • 84
    • 32644456874 scopus 로고    scopus 로고
    • Antiviral innate immunity pathways
    • Seth, R. B., Sun, L., and Chen, Z. J. (2006). Antiviral innate immunity pathways. Cell Res. 16, 141-147.
    • (2006) Cell Res , vol.16 , pp. 141-147
    • Seth, R.B.1    Sun, L.2    Chen, Z.J.3
  • 85
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
    • Seth, R. B., Sun, L., Ea, C. K., and Chen, Z. J. (2005). Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122, 669-682.
    • (2005) Cell , vol.122 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.K.3    Chen, Z.J.4
  • 86
    • 21244499845 scopus 로고    scopus 로고
    • The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alphasynuclein degradation decisions between proteasomal and lysosomal pathways
    • Shin, Y., Klucken, J., Patterson, C., Hyman, B. T., and Mclean, P. J. (2005). The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alphasynuclein degradation decisions between proteasomal and lysosomal pathways. J. Biol. Chem. 280, 23727-23734.
    • (2005) J. Biol. Chem. , vol.280 , pp. 23727-23734
    • Shin, Y.1    Klucken, J.2    Patterson, C.3    Hyman, B.T.4    Mclean, P.J.5
  • 87
    • 0035883151 scopus 로고    scopus 로고
    • NF-kappaB signaling pathways in mammalian and insect innate immunity
    • Silverman, N., and Maniatis, T. (2001). NF-kappaB signaling pathways in mammalian and insect innate immunity. Genes Dev. 15, 2321-2342.
    • (2001) Genes Dev , vol.15 , pp. 2321-2342
    • Silverman, N.1    Maniatis, T.2
  • 88
    • 77957785465 scopus 로고    scopus 로고
    • Emerging role of ISG15 in antiviral immunity
    • Skaug, B., and Chen, Z. J. (2010). Emerging role of ISG15 in antiviral immunity. Cell 143, 187-190.
    • (2010) Cell , vol.143 , pp. 187-190
    • Skaug, B.1    Chen, Z.J.2
  • 89
    • 79953288616 scopus 로고    scopus 로고
    • Clinical correlates of similar pathologies in parkinsonian syndromes
    • Song, Y. J., Huang, Y., and Halliday, G. M. (2011). Clinical correlates of similar pathologies in parkinsonian syndromes. Mov. Disord. 26, 499-506.
    • (2011) Mov. Disord. , vol.26 , pp. 499-506
    • Song, Y.J.1    Huang, Y.2    Halliday, G.M.3
  • 90
    • 80052473816 scopus 로고    scopus 로고
    • Toll-like receptor 4 promotes alpha-synuclein clearance and survival of nigral dopaminergic neurons
    • Stefanova, N., Fellner, L., Reindl, M., Masliah, E., Poewe, W., and Wenning, G. K. (2011). Toll-like receptor 4 promotes alpha-synuclein clearance and survival of nigral dopaminergic neurons. Am. J. Pathol. 179, 954-963.
    • (2011) Am. J. Pathol. , vol.179 , pp. 954-963
    • Stefanova, N.1    Fellner, L.2    Reindl, M.3    Masliah, E.4    Poewe, W.5    Wenning, G.K.6
  • 91
    • 79955882722 scopus 로고    scopus 로고
    • Nonsteroidal analgesics have a protective effect against Parkinson disease
    • Steurer, J. (2011). [Nonsteroidal analgesics have a protective effect against Parkinson disease]. Praxis (Bern 1994) 100, 617-618.
    • (2011) Praxis (Bern 1994) , vol.100 , pp. 617-618
    • Steurer, J.1
  • 92
    • 68249145501 scopus 로고    scopus 로고
    • Innate and adaptive immunity for the pathobiology of Parkinson's disease
    • Stone, D. K., Reynolds, A. D., Mosley, R. L., and Gendelman, H. E. (2009). Innate and adaptive immunity for the pathobiology of Parkinson's disease. Antioxid. Redox Signal. 11, 2151-2166.
    • (2009) Antioxid. Redox Signal. , vol.11 , pp. 2151-2166
    • Stone, D.K.1    Reynolds, A.D.2    Mosley, R.L.3    Gendelman, H.E.4
  • 94
    • 33748751765 scopus 로고    scopus 로고
    • Histone deacetylase (HDAC) 4 involvement in both Lewy and Marinesco bodies
    • Takahashi-Fujigasaki, J., and Fujigasaki, H. (2006). Histone deacetylase (HDAC) 4 involvement in both Lewy and Marinesco bodies. Neuropathol. Appl. Neurobiol. 32, 562-566.
    • (2006) Neuropathol. Appl. Neurobiol. , vol.32 , pp. 562-566
    • Takahashi-Fujigasaki, J.1    Fujigasaki, H.2
  • 95
    • 0035870881 scopus 로고    scopus 로고
    • Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
    • Tanaka, Y., Engelender, S., Igarashi, S., Rao, R. K., Wanner, T., Tanzi, R. E., Sawa, A., V, L. D., Dawson, T. M., and Ross, C. A. (2001). Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Hum. Mol. Genet. 10, 919-926.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 919-926
    • Tanaka, Y.1    Engelender, S.2    Igarashi, S.3    Rao, R.K.4    Wanner, T.5    Tanzi, R.E.6    Sawa, A.V.L.D.7    Dawson, T.M.8    Ross, C.A.9
  • 96
    • 77949427242 scopus 로고    scopus 로고
    • TRAF5 is a downstream target of MAVS in antiviral innate immune signaling
    • doi:10.1371/journal.pone.0009172
    • Tang, E. D., and Wang, C. Y. (2010). TRAF5 is a downstream target of MAVS in antiviral innate immune signaling. PLoS ONE 5, e9172. doi:10.1371/journal.pone.0009172
    • (2010) PLoS ONE , vol.5
    • Tang, E.D.1    Wang, C.Y.2
  • 98
    • 80855131625 scopus 로고    scopus 로고
    • Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis
    • Umeno, J., Asano, K., Matsushita, T., Matsumoto, T., Kiyohara, Y., Iida, M., Nakamura, Y., Kamatani, N., and Kubo, M. (2011). Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis. Inflamm. Bowel. Dis. 17, 2407-2415.
    • (2011) Inflamm. Bowel. Dis. , vol.17 , pp. 2407-2415
    • Umeno, J.1    Asano, K.2    Matsushita, T.3    Matsumoto, T.4    Kiyohara, Y.5    Iida, M.6    Nakamura, Y.7    Kamatani, N.8    Kubo, M.9
  • 102
    • 0346850824 scopus 로고    scopus 로고
    • Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction
    • Visintin, A., Latz, E., Monks, B. G., Espevik, T., and Golenbock, D. T. (2003). Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction. J. Biol. Chem. 278, 48313-48320.
    • (2003) J. Biol. Chem. , vol.278 , pp. 48313-48320
    • Visintin, A.1    Latz, E.2    Monks, B.G.3    Espevik, T.4    Golenbock, D.T.5
  • 103
    • 35948985533 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs may protect against Parkinson disease
    • Wahner, A. D., Bronstein, J. M., Bordelon, Y. M., and Ritz, B. (2007). Nonsteroidal anti-inflammatory drugs may protect against Parkinson disease. Neurology 69, 1836-1842.
    • (2007) Neurology , vol.69 , pp. 1836-1842
    • Wahner, A.D.1    Bronstein, J.M.2    Bordelon, Y.M.3    Ritz, B.4
  • 106
    • 79957597757 scopus 로고    scopus 로고
    • Mitochondria in innate immune responses
    • West, A. P., Shadel, G. S., and Ghosh, S. (2011). Mitochondria in innate immune responses. Nat. Rev. Immunol. 11, 389-402.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 389-402
    • West, A.P.1    Shadel, G.S.2    Ghosh, S.3
  • 107
    • 0037366093 scopus 로고    scopus 로고
    • Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: implications for Parkinson's disease
    • Wilms, H., Rosenstiel, P., Sievers, J., Deuschl, G., Zecca, L., and Lucius, R. (2003). Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: implications for Parkinson's disease. FASEB J. 17, 500-502
    • (2003) FASEB J , vol.17 , pp. 500-502
    • Wilms, H.1    Rosenstiel, P.2    Sievers, J.3    Deuschl, G.4    Zecca, L.5    Lucius, R.6
  • 108
    • 79551510429 scopus 로고    scopus 로고
    • AnovelroleforATMinregulating proteasome-mediated protein degradation through suppression of the ISG15 conjugation pathway
    • doi:10.1371/journal.pone.0016422
    • Wood, L. M., Sankar, S., Reed, R. E., Haas, A. L., Liu, L. F., Mckinnon, P., and Desai, S. D. (2011). AnovelroleforATMinregulating proteasome-mediated protein degradation through suppression of the ISG15 conjugation pathway. PLoS ONE 6, e16422. doi:10.1371/journal.pone.0016422
    • (2011) PLoS ONE , vol.6
    • Wood, L.M.1    Sankar, S.2    Reed, R.E.3    Haas, A.L.4    Liu, L.F.5    Mckinnon, P.6    Desai, S.D.7
  • 109
    • 33645703930 scopus 로고    scopus 로고
    • NEMO is a sensor of Lys 63-linked polyubiquitination and functions in NF-kappaB activation
    • Wu, C. J., Conze, D. B., Li, T., Srinivasula, S. M., and Ashwell, J. D. (2006). NEMO is a sensor of Lys 63-linked polyubiquitination and functions in NF-kappaB activation. Nat. Cell Biol. 8, 398-406.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 398-406
    • Wu, C.J.1    Conze, D.B.2    Li, T.3    Srinivasula, S.M.4    Ashwell, J.D.5
  • 110
    • 0034700158 scopus 로고    scopus 로고
    • Parkin functions as an E2dependent ubiquitinprotein ligase and promotes the degradation of the synaptic vesicle-associated protein CDCrel-1
    • Zhang, Y., Gao, J., Chung, K. K., Huang, H., Dawson,V. L., and Dawson, T. M. (2000). Parkin functions as an E2dependent ubiquitinprotein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proc. Natl. Acad. Sci. U.S.A. 97, 13354-13359.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 13354-13359
    • Zhang, Y.1    Gao, J.2    Chung, K.K.3    Huang, H.4    Dawson, V.L.5    Dawson, T.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.