-
1
-
-
79959216005
-
Genetics and pathogenesis of inflammatory bowel disease
-
Khor B, Gardet A, Xavier RJ,. Genetics and pathogenesis of inflammatory bowel disease. Nature. 2011; 474: 307-317.
-
(2011)
Nature
, vol.474
, pp. 307-317
-
-
Khor, B.1
Gardet, A.2
Xavier, R.J.3
-
2
-
-
79952195585
-
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
-
Anderson CA, Boucher G, Lees CW, et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet. 2011; 43: 246-252.
-
(2011)
Nat Genet
, vol.43
, pp. 246-252
-
-
Anderson, C.A.1
Boucher, G.2
Lees, C.W.3
-
3
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke A, McGovern DP, Barrett JC, et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet. 2011; 42: 1118-1125.
-
(2011)
Nat Genet
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
-
4
-
-
67651177623
-
MAST3: A novel IBD risk factor that modulates TLR4 signaling
-
Labbe C, Goyette P, Lefebvre C, et al. MAST3: a novel IBD risk factor that modulates TLR4 signaling. Genes Immun. 2008; 9: 602-612.
-
(2008)
Genes Immun
, vol.9
, pp. 602-612
-
-
Labbe, C.1
Goyette, P.2
Lefebvre, C.3
-
5
-
-
39149127954
-
Expression of the MAST family of serine/threonine kinases
-
Garland P, Quraishe S, French P, et al. Expression of the MAST family of serine/threonine kinases. Brain Res. 2008; 1195: 12-19.
-
(2008)
Brain Res
, vol.1195
, pp. 12-19
-
-
Garland, P.1
Quraishe, S.2
French, P.3
-
6
-
-
6344243618
-
Interaction of TRAF6 with MAST205 regulates NF-kappaB activation and MAST205 stability
-
Xiong H, Li H, Chen Y, et al. Interaction of TRAF6 with MAST205 regulates NF-kappaB activation and MAST205 stability. J Biol Chem. 2004; 279: 43675-43683.
-
(2004)
J Biol Chem
, vol.279
, pp. 43675-43683
-
-
Xiong, H.1
Li, H.2
Chen, Y.3
-
7
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
Gentleman RC, Carey VJ, Bates DM, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 2004; 5: R80.
-
(2004)
Genome Biol
, vol.5
-
-
Gentleman, R.C.1
Carey, V.J.2
Bates, D.M.3
-
8
-
-
46249088370
-
Lumi: A pipeline for processing Illumina microarray
-
Du P, Kibbe WA, Lin SM,. Lumi: a pipeline for processing Illumina microarray. Bioinformatics. 2008; 24: 1547-1548.
-
(2008)
Bioinformatics
, vol.24
, pp. 1547-1548
-
-
Du, P.1
Kibbe, W.A.2
Lin, S.M.3
-
10
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang da W, Sherman BT, Lempicki RA,. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 2009; 4: 44-57.
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang Da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
11
-
-
0037316303
-
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
-
Bolstad BM, Irizarry RA, Astrand M, et al. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics. 2003; 19: 185-193.
-
(2003)
Bioinformatics
, vol.19
, pp. 185-193
-
-
Bolstad, B.M.1
Irizarry, R.A.2
Astrand, M.3
-
12
-
-
1342288026
-
Affy-analysis of Affymetrix GeneChip data at the probe level
-
Gautier L, Cope L, Bolstad BM, et al. Affy-analysis of Affymetrix GeneChip data at the probe level. Bioinformatics. 2004; 20: 307-315.
-
(2004)
Bioinformatics
, vol.20
, pp. 307-315
-
-
Gautier, L.1
Cope, L.2
Bolstad, B.M.3
-
13
-
-
79952081448
-
CCR6 as a mediator of immunity in the lung and gut
-
Ito T, Carson WFT, Cavassani KA, et al. CCR6 as a mediator of immunity in the lung and gut. Exp Cell Res. 2011; 317: 613-619.
-
(2011)
Exp Cell Res
, vol.317
, pp. 613-619
-
-
Ito, T.1
Carson, W.F.T.2
Cavassani, K.A.3
-
14
-
-
0030067724
-
Increased interleukin 8 expression in the colon mucosa of patients with inflammatory bowel disease
-
Daig R, Andus T, Aschenbrenner E, et al. Increased interleukin 8 expression in the colon mucosa of patients with inflammatory bowel disease. Gut. 1996; 38: 216-222.
-
(1996)
Gut
, vol.38
, pp. 216-222
-
-
Daig, R.1
Andus, T.2
Aschenbrenner, E.3
-
15
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature. 2001; 411: 599-603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
-
16
-
-
4444332518
-
Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations
-
Li J, Moran T, Swanson E, et al. Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations. Hum Mol Genet. 2004; 13: 1715-1725.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1715-1725
-
-
Li, J.1
Moran, T.2
Swanson, E.3
-
17
-
-
77749298990
-
Molecular mechanisms of system control of NF-kappaB signaling by IkappaBalpha
-
Ferreiro DU, Komives EA,. Molecular mechanisms of system control of NF-kappaB signaling by IkappaBalpha. Biochemistry. 2010; 49: 1560-1567.
-
(2010)
Biochemistry
, vol.49
, pp. 1560-1567
-
-
Ferreiro, D.U.1
Komives, E.A.2
-
18
-
-
0032939356
-
The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kappaB activation at the level of TRAF6
-
Heyninck K, Beyaert R,. The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kappaB activation at the level of TRAF6. FEBS Lett. 1999; 442: 147-150.
-
(1999)
FEBS Lett
, vol.442
, pp. 147-150
-
-
Heyninck, K.1
Beyaert, R.2
-
19
-
-
0037418749
-
Regulation of Toll-like receptor 4 signalling by A20 zinc finger protein
-
O'Reilly SM, Moynagh PN,. Regulation of Toll-like receptor 4 signalling by A20 zinc finger protein. Biochem Biophys Res Commun. 2003; 303: 586-593.
-
(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 586-593
-
-
O'Reilly, S.M.1
Moynagh, P.N.2
-
20
-
-
67349182481
-
The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
-
Park BS, Song DH, Kim HM, et al. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature. 2009; 458: 1191-1195.
-
(2009)
Nature
, vol.458
, pp. 1191-1195
-
-
Park, B.S.1
Song, D.H.2
Kim, H.M.3
-
21
-
-
41949114612
-
IEX-1 directly interferes with RelA/p65 dependent transactivation and regulation of apoptosis
-
Arlt A, Rosenstiel P, Kruse ML, et al. IEX-1 directly interferes with RelA/p65 dependent transactivation and regulation of apoptosis. Biochim Biophys Acta. 2008; 1783: 941-952.
-
(2008)
Biochim Biophys Acta
, vol.1783
, pp. 941-952
-
-
Arlt, A.1
Rosenstiel, P.2
Kruse, M.L.3
-
22
-
-
79955018886
-
Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC
-
Billmann-Born S, Till A, Arlt A, et al. Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC. J Immunol. 2011; 186: 4027-4038.
-
(2011)
J Immunol
, vol.186
, pp. 4027-4038
-
-
Billmann-Born, S.1
Till, A.2
Arlt, A.3
-
23
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi KS, Chamaillard M, Ogura Y, et al. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science. 2005; 307: 731-734.
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
-
24
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett JC, Hansoul S, Nicolae DL, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet. 2008; 40: 955-962.
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
-
25
-
-
0026531017
-
Tumour necrosis factor alpha in stool as a marker of intestinal inflammation
-
Braegger CP, Nicholls S, Murch SH, et al. Tumour necrosis factor alpha in stool as a marker of intestinal inflammation. Lancet. 1992; 339: 89-91.
-
(1992)
Lancet
, vol.339
, pp. 89-91
-
-
Braegger, C.P.1
Nicholls, S.2
Murch, S.H.3
-
26
-
-
0027451455
-
Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease
-
Reinecker HC, Steffen M, Witthoeft T, et al. Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease. Clin Exp Immunol. 1993; 94: 174-181.
-
(1993)
Clin Exp Immunol
, vol.94
, pp. 174-181
-
-
Reinecker, H.C.1
Steffen, M.2
Witthoeft, T.3
-
27
-
-
0037018761
-
Maintenance infliximab for Crohn's disease: The ACCENT i randomised trial
-
Hanauer SB, Feagan BG, Lichtenstein GR, et al. Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet. 2002; 359: 1541-1549.
-
(2002)
Lancet
, vol.359
, pp. 1541-1549
-
-
Hanauer, S.B.1
Feagan, B.G.2
Lichtenstein, G.R.3
-
28
-
-
10744221312
-
Infliximab maintenance therapy for fistulizing Crohn's disease
-
Sands BE, Anderson FH, Bernstein CN, et al. Infliximab maintenance therapy for fistulizing Crohn's disease. N Engl J Med. 2004; 350: 876-885.
-
(2004)
N Engl J Med
, vol.350
, pp. 876-885
-
-
Sands, B.E.1
Anderson, F.H.2
Bernstein, C.N.3
-
29
-
-
0036066936
-
Infliximab improves quality of life in patients with Crohn's disease
-
Lichtenstein GR, Bala M, Han C, et al. Infliximab improves quality of life in patients with Crohn's disease. Inflamm Bowel Dis. 2002; 8: 237-243.
-
(2002)
Inflamm Bowel Dis
, vol.8
, pp. 237-243
-
-
Lichtenstein, G.R.1
Bala, M.2
Han, C.3
-
30
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group
-
Targan SR, Hanauer SB, van Deventer SJ, et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med. 1997; 337: 1029-1035.
-
(1997)
N Engl J Med
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
Van Deventer, S.J.3
-
31
-
-
56149122030
-
CD137 induces proliferation of murine hematopoietic progenitor cells and differentiation to macrophages
-
Jiang D, Chen Y, Schwarz H,. CD137 induces proliferation of murine hematopoietic progenitor cells and differentiation to macrophages. J Immunol. 2008; 181: 3923-3932.
-
(2008)
J Immunol
, vol.181
, pp. 3923-3932
-
-
Jiang, D.1
Chen, Y.2
Schwarz, H.3
-
32
-
-
0036075444
-
In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses
-
Halstead ES, Mueller YM, Altman JD, et al. In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses. Nat Immunol. 2002; 3: 536-541.
-
(2002)
Nat Immunol
, vol.3
, pp. 536-541
-
-
Halstead, E.S.1
Mueller, Y.M.2
Altman, J.D.3
-
33
-
-
0031962348
-
4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB
-
Arch RH, Thompson CB,. 4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB. Mol Cell Biol. 1998; 18: 558-565.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 558-565
-
-
Arch, R.H.1
Thompson, C.B.2
-
34
-
-
40449111457
-
Human Th17 cells share major trafficking receptors with both polarized effector T cells and FOXP3+ regulatory T cells
-
Lim HW, Lee J, Hillsamer P, et al. Human Th17 cells share major trafficking receptors with both polarized effector T cells and FOXP3+ regulatory T cells. J Immunol. 2008; 180: 122-129.
-
(2008)
J Immunol
, vol.180
, pp. 122-129
-
-
Lim, H.W.1
Lee, J.2
Hillsamer, P.3
-
35
-
-
67650224449
-
Crohn's disease: Th1, Th17 or both? the change of a paradigm: New immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease
-
Brand S,. Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease. Gut. 2009; 58: 1152-1167.
-
(2009)
Gut
, vol.58
, pp. 1152-1167
-
-
Brand, S.1
|