The Co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates α-synuclein degradation decisions between proteasomal and lysosomal pathways

Journal of Biological Chemistry

Volumn 280, Issue 25, 2005, Pages 23727-23734

  Shin, Youngah ^a   Klucken, Jochen ^a   Patterson, Cam ^b   Hyman, Bradley T ^a   McLean, Pamela J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; CELL CULTURE; DISEASES; IMMUNOLOGY; NEUROLOGY; PATHOLOGY;

IMMUNOPRECIPITATION; LYPOSOMAL DEGRADATION; PARKINSON DISEASES; PATHOGENESIS;

PROTEINS;

ALPHA SYNUCLEIN; CARBOXYL GROUP; CARBOXYL TERMINUS OF HSP 70 INTERACTING PROTEIN; CHAPERONE; HEAT SHOCK PROTEIN 70; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; LEWY BODY; LYSOSOME MEMBRANE; PRIORITY JOURNAL; PROTEIN DEGRADATION; TETRATRICOPEPTIDE REPEAT;

ALPHA-SYNUCLEIN; CELL LINE, TUMOR; HUMANS; HYDROLYSIS; LEWY BODIES; LYSOSOMES; MOLECULAR CHAPERONES; NERVE TISSUE PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; SYNUCLEINS; UBIQUITIN-PROTEIN LIGASES;

EID: 21244499845     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M503326200     Document Type: Article

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