-
1
-
-
26844504704
-
A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis
-
Ding B, Abe J, Wei H, Xu H, Che W, Aizawa T, Liu W, Molina C A, Sadoshima J, Blaxall B C, Berk B C, Yan C. A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis. Proc Natl Acad Sci USA: 2005; 102 14771 14776
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 14771-14776
-
-
Ding, B.1
Abe, J.2
Wei, H.3
Xu, H.4
Che, W.5
Aizawa, T.6
Liu, W.7
Molina, C.A.8
Sadoshima, J.9
Blaxall, B.C.10
Berk, B.C.11
Yan, C.12
-
2
-
-
79957755423
-
Phosphodiesterases and cardiac cGMP: Evolving roles and controversies
-
Zhang M, Kass D A. Phosphodiesterases and cardiac cGMP: evolving roles and controversies. Trends Pharmacol Sci: 2011; 32 360 365
-
(2011)
Trends Pharmacol Sci
, vol.32
, pp. 360-365
-
-
Zhang, M.1
Kass, D.A.2
-
3
-
-
34447099952
-
New insights into the regulation of cAMP synthesis beyond GPCR/G protein activation: Implications in cardiovascular regulation
-
Feldman R D, Gros R. New insights into the regulation of cAMP synthesis beyond GPCR/G protein activation: Implications in cardiovascular regulation. Life Sci: 2007; 81 267 271
-
(2007)
Life Sci
, vol.81
, pp. 267-271
-
-
Feldman, R.D.1
Gros, R.2
-
5
-
-
54249163411
-
Spatial and temporal aspects of cAMP signalling in cardiac myocytes
-
Iancu R V, Ramamurthy G, Harvey R D. Spatial and temporal aspects of cAMP signalling in cardiac myocytes. Clin Exp Pharmacol Physiol: 2008; 35 1343 1348
-
(2008)
Clin Exp Pharmacol Physiol
, vol.35
, pp. 1343-1348
-
-
Iancu, R.V.1
Ramamurthy, G.2
Harvey, R.D.3
-
6
-
-
77955853530
-
Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, β-arrestin 2, PDE4D3 complex
-
Halls M L, Cooper DM F. Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, β-arrestin 2, PDE4D3 complex. EMBO J: 2010; 29 2772 2787
-
(2010)
EMBO J
, vol.29
, pp. 2772-2787
-
-
Halls, M.L.1
Cooper, D.M.F.2
-
7
-
-
69249211018
-
CAMP signal transduction in the heart: Understanding spatial control for the development of novel therapeutic strategies
-
Zaccolo M. cAMP signal transduction in the heart: understanding spatial control for the development of novel therapeutic strategies. Br J Pharmacol: 2009; 158 50 60
-
(2009)
Br J Pharmacol
, vol.158
, pp. 50-60
-
-
Zaccolo, M.1
-
8
-
-
77950930736
-
Role of the cAMP-binding protein Epac in cardiovascular physiology and pathophysiology
-
Métrich M, Berthouze M, Morel E, Crozatier B, Gomez A M, Lezoualc'h F. Role of the cAMP-binding protein Epac in cardiovascular physiology and pathophysiology. Pflügers Archiv Eur J Physiol: 2009; 459 535 546
-
(2009)
Pflügers Archiv Eur J Physiol
, vol.459
, pp. 535-546
-
-
Métrich, M.1
Berthouze, M.2
Morel, E.3
Crozatier, B.4
Gomez, A.M.5
Lezoualc'H, F.6
-
9
-
-
67349149420
-
Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics
-
Tsai E J, Kass D A. Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics. Pharmacol Ther: 2009; 122 216 238
-
(2009)
Pharmacol Ther
, vol.122
, pp. 216-238
-
-
Tsai, E.J.1
Kass, D.A.2
-
10
-
-
33646795266
-
Cyclic guanosine monophosphate compartmentation in rat cardiac myocytes
-
Castro LR V, Verde I, Cooper D M, Fischmeister R. Cyclic guanosine monophosphate compartmentation in rat cardiac myocytes. Circulation: 2006; 113 2221 2228
-
(2006)
Circulation
, vol.113
, pp. 2221-2228
-
-
Castro, L.R.V.1
Verde, I.2
Cooper, D.M.3
Fischmeister, R.4
-
11
-
-
33748686575
-
Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use
-
Bender A T, Beavo J A. Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use. Pharmacol Rev: 2006; 58 488 520
-
(2006)
Pharmacol Rev
, vol.58
, pp. 488-520
-
-
Bender, A.T.1
Beavo, J.A.2
-
12
-
-
34447265905
-
Biochemistry and Physiology of Cyclic Nucleotide Phosphodiesterases: Essential Components in Cyclic Nucleotide Signaling
-
Conti M, Beavo J. Biochemistry and Physiology of Cyclic Nucleotide Phosphodiesterases: Essential Components in Cyclic Nucleotide Signaling. Annu Rev Biochem: 2007; 76 481 511
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 481-511
-
-
Conti, M.1
Beavo, J.2
-
13
-
-
77958095148
-
Targeting cyclic nucleotide phosphodiesterase in the heart: Therapeutic implications
-
Miller C L, Yan C. Targeting cyclic nucleotide phosphodiesterase in the heart: therapeutic implications. J Cardiovasc Transl Res: 2010; 3 507 515
-
(2010)
J Cardiovasc Transl Res
, vol.3
, pp. 507-515
-
-
Miller, C.L.1
Yan, C.2
-
14
-
-
0027509357
-
Molecular cloning of a cDNA encoding the "61-kDao" calmodulin-stimulated cyclic nucleotide phosphodiesterase. Tissue-specific expression of structurally related isoforms
-
Sonnenburg W K, Seger D, Beavo J A. Molecular cloning of a cDNA encoding the "61-kDao" calmodulin-stimulated cyclic nucleotide phosphodiesterase. Tissue-specific expression of structurally related isoforms. J Biol Chem: 1993; 268 645 652
-
(1993)
J Biol Chem
, vol.268
, pp. 645-652
-
-
Sonnenburg, W.K.1
Seger, D.2
Beavo, J.A.3
-
15
-
-
0029845929
-
The Calmodulin-dependent Phosphodiesterase Gene PDE1C Encodes Several Functionally Different Splice Variants in a Tissue-specific Manner
-
Yan C, Zhao A Z, Bentley J K, Beavo J A. The Calmodulin-dependent Phosphodiesterase Gene PDE1C Encodes Several Functionally Different Splice Variants in a Tissue-specific Manner. J Biol Chem: 1996; 271 25699 25706
-
(1996)
J Biol Chem
, vol.271
, pp. 25699-25706
-
-
Yan, C.1
Zhao, A.Z.2
Bentley, J.K.3
Beavo, J.A.4
-
17
-
-
72449174812
-
Role of Ca2+/Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterase 1 in Mediating Cardiomyocyte Hypertrophy
-
Miller C L, Oikawa M, Cai Y, Wojtovich A P, Nagel D J, Xu X, Xu H, Florio V, Rybalkin S D, Beavo J A, Chen Y-F, Li J-D, Blaxall B C, Abe J, Yan C. Role of Ca2+/Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterase 1 in Mediating Cardiomyocyte Hypertrophy. Circ Res: 2009; 105 956 964
-
(2009)
Circ Res
, vol.105
, pp. 956-964
-
-
Miller, C.L.1
Oikawa, M.2
Cai, Y.3
Wojtovich, A.P.4
Nagel, D.J.5
Xu, X.6
Xu, H.7
Florio, V.8
Rybalkin, S.D.9
Beavo, J.A.10
Chen, Y.-F.11
Li, J.-D.12
Blaxall, B.C.13
Abe, J.14
Yan, C.15
-
18
-
-
33645743686
-
Role of Nuclear Ca2+/Calmodulin-Stimulated Phosphodiesterase 1A in Vascular Smooth Muscle Cell Growth and Survival
-
Nagel D J, Aizawa T, Jeon K-I, Liu W, Mohan A, Wei H, Miano J M, Florio V A, Gao P, Korshunov V A, Berk B C, Yan C. Role of Nuclear Ca2+/Calmodulin- Stimulated Phosphodiesterase 1A in Vascular Smooth Muscle Cell Growth and Survival. Circ Res: 2006; 98 777 784
-
(2006)
Circ Res
, vol.98
, pp. 777-784
-
-
Nagel, D.J.1
Aizawa, T.2
Jeon, K.-I.3
Liu, W.4
Mohan, A.5
Wei, H.6
Miano, J.M.7
Florio, V.A.8
Gao, P.9
Korshunov, V.A.10
Berk, B.C.11
Yan, C.12
-
19
-
-
84856720930
-
Cyclic nucleotide phosphodiesterase 1A: A key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart
-
Miller C L, Cai Y, Oikawa M, Thomas T, Dostmann W R, Zaccolo M, Fujiwara K, Yan C. Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart. Basic Res Cardiol: 2011; 106 1023 1039
-
(2011)
Basic Res Cardiol
, vol.106
, pp. 1023-1039
-
-
Miller, C.L.1
Cai, Y.2
Oikawa, M.3
Thomas, T.4
Dostmann, W.R.5
Zaccolo, M.6
Fujiwara, K.7
Yan, C.8
-
20
-
-
31044446734
-
PDE1B2 regulates cGMP and a subset of the phenotypic characteristics acquired upon macrophage differentiation from a monocyte
-
Bender A T, Beavo J A. PDE1B2 regulates cGMP and a subset of the phenotypic characteristics acquired upon macrophage differentiation from a monocyte. Proc Natl Acad Sci USA: 2006; 103 460 465
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 460-465
-
-
Bender, A.T.1
Beavo, J.A.2
-
21
-
-
0037096253
-
Phosphodiesterase 1B Knock-Out Mice Exhibit Exaggerated Locomotor Hyperactivity and DARPP-32 Phosphorylation in Response to Dopamine Agonists and Display Impaired Spatial Learning
-
Reed T M, Repaske D R, Snyder G L, Greengard P, Vorhees C V. Phosphodiesterase 1B Knock-Out Mice Exhibit Exaggerated Locomotor Hyperactivity and DARPP-32 Phosphorylation in Response to Dopamine Agonists and Display Impaired Spatial Learning. J Neurosci: 2002; 22 5188 5197
-
(2002)
J Neurosci
, vol.22
, pp. 5188-5197
-
-
Reed, T.M.1
Repaske, D.R.2
Snyder, G.L.3
Greengard, P.4
Vorhees, C.V.5
-
22
-
-
0035882756
-
Regulatory roles of adenylate cyclase and cyclic nucleotide phosphodiesterases 1 and 4 in interleukin-13 production by activated human T cells
-
Kanda N, Watanabe S. Regulatory roles of adenylate cyclase and cyclic nucleotide phosphodiesterases 1 and 4 in interleukin-13 production by activated human T cells. Biochem Pharmacol: 2001; 62 495 507
-
(2001)
Biochem Pharmacol
, vol.62
, pp. 495-507
-
-
Kanda, N.1
Watanabe, S.2
-
23
-
-
0037040155
-
Cyclic nucleotide phosphodiesterase 1C promotes human arterial smooth muscle cell proliferation
-
Rybalkin S D, Rybalkina I, Beavo J A, Bornfeldt K E. Cyclic nucleotide phosphodiesterase 1C promotes human arterial smooth muscle cell proliferation. Circ Res: 2002; 90 151 157
-
(2002)
Circ Res
, vol.90
, pp. 151-157
-
-
Rybalkin, S.D.1
Rybalkina, I.2
Beavo, J.A.3
Bornfeldt, K.E.4
-
24
-
-
0033529693
-
The calcium/calmodulin-dependent phosphodiesterase PDE1C down-regulates glucose-induced insulin secretion
-
Han P, Werber J, Surana M, Fleischer N, Michaeli T. The calcium/calmodulin-dependent phosphodiesterase PDE1C down-regulates glucose-induced insulin secretion. J Biol Chem: 1999; 274 22337 22344
-
(1999)
J Biol Chem
, vol.274
, pp. 22337-22344
-
-
Han, P.1
Werber, J.2
Surana, M.3
Fleischer, N.4
Michaeli, T.5
-
25
-
-
34548428382
-
Characterization of inhibitors of phosphodiesterase 1C on a human cellular system
-
Dunkern T R, Hatzelmann A. Characterization of inhibitors of phosphodiesterase 1C on a human cellular system. FEBS J: 2007; 274 4812 4824
-
(2007)
FEBS J
, vol.274
, pp. 4812-4824
-
-
Dunkern, T.R.1
Hatzelmann, A.2
-
26
-
-
0033522211
-
Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissue cyclic nucleotides, platelet function, and the contractile responses of trabeculae carneae and aortic rings in vitro
-
Wallis R M, Corbin J D, Francis S H, Ellis P. Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissue cyclic nucleotides, platelet function, and the contractile responses of trabeculae carneae and aortic rings in vitro. Am J Cardiol: 1999; 83 3 12
-
(1999)
Am J Cardiol
, vol.83
, pp. 3-12
-
-
Wallis, R.M.1
Corbin, J.D.2
Francis, S.H.3
Ellis, P.4
-
27
-
-
36348933827
-
Cyclic Nucleotide Phosphodiesterase PDE1C1 in Human Cardiac Myocytes
-
Vandeput F, Wolda S L, Krall J, Hambleton R, Uher L, McCaw K N, Radwanski P B, Florio V, Movsesian M A. Cyclic Nucleotide Phosphodiesterase PDE1C1 in Human Cardiac Myocytes. J Biol Chem: 2007; 282 32749 32757
-
(2007)
J Biol Chem
, vol.282
, pp. 32749-32757
-
-
Vandeput, F.1
Wolda, S.L.2
Krall, J.3
Hambleton, R.4
Uher, L.5
McCaw, K.N.6
Radwanski, P.B.7
Florio, V.8
Movsesian, M.A.9
-
28
-
-
0030064790
-
Isolation and Characterization of cDNAs Corresponding to Two Human Calcium, Calmodulin-regulated, 3,5-Cyclic Nucleotide Phosphodiesterases
-
Loughney K, Martins T J, Harris EA S, Sadhu K, Hicks J B, Sonnenburg W K, Beavo J A, Ferguson K. Isolation and Characterization of cDNAs Corresponding to Two Human Calcium, Calmodulin-regulated, 3,5-Cyclic Nucleotide Phosphodiesterases. J Biol Chem: 1996; 271 796 806
-
(1996)
J Biol Chem
, vol.271
, pp. 796-806
-
-
Loughney, K.1
Martins, T.J.2
Harris, E.A.S.3
Sadhu, K.4
Hicks, J.B.5
Sonnenburg, W.K.6
Beavo, J.A.7
Ferguson, K.8
-
30
-
-
3142723295
-
Fluorescence Resonance Energy Transfer-Based Analysis of cAMP Dynamics in Live Neonatal Rat Cardiac Myocytes Reveals Distinct Functions of Compartmentalized Phosphodiesterases
-
Mongillo M, McSorley T, Evellin S, Sood A, Lissandron V, Terrin A, Huston E, Hannawacker A, Lohse M J, Pozzan T, Houslay M D, Zaccolo M. Fluorescence Resonance Energy Transfer-Based Analysis of cAMP Dynamics in Live Neonatal Rat Cardiac Myocytes Reveals Distinct Functions of Compartmentalized Phosphodiesterases. Circ Res: 2004; 95 67 75
-
(2004)
Circ Res
, vol.95
, pp. 67-75
-
-
Mongillo, M.1
McSorley, T.2
Evellin, S.3
Sood, A.4
Lissandron, V.5
Terrin, A.6
Huston, E.7
Hannawacker, A.8
Lohse, M.J.9
Pozzan, T.10
Houslay, M.D.11
Zaccolo, M.12
-
31
-
-
34250615897
-
Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice
-
Sun B, Li H, Shakur Y, Hensley J, Hockman S, Kambayashi J, Manganiello V C, Liu Y. Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice. Cell Signal: 2007; 19 1765 1771
-
(2007)
Cell Signal
, vol.19
, pp. 1765-1771
-
-
Sun, B.1
Li, H.2
Shakur, Y.3
Hensley, J.4
Hockman, S.5
Kambayashi, J.6
Manganiello, V.C.7
Liu, Y.8
-
32
-
-
0032410693
-
Importance of phosphodiesterase 3 for the lipolytic response in adipose tissue during insulin-induced hypoglycemia in normal man
-
Moberg E, Enoksson S, Hagström-Toft E. Importance of phosphodiesterase 3 for the lipolytic response in adipose tissue during insulin-induced hypoglycemia in normal man. Horm Metab Res: 1998; 30 684 688
-
(1998)
Horm Metab Res
, vol.30
, pp. 684-688
-
-
Moberg, E.1
Enoksson, S.2
Hagström-Toft, E.3
-
33
-
-
0035148960
-
Identification of a novel isoform of the cyclic-nucleotide phosphodiesterase PDE3A expressed in vascular smooth-muscle myocytes
-
Choi Y H, Ekholm D, Krall J, Ahmad F, Degerman E, Manganiello V C, Movsesian M A. Identification of a novel isoform of the cyclic-nucleotide phosphodiesterase PDE3A expressed in vascular smooth-muscle myocytes. Biochem J: 2001; 353 41 50
-
(2001)
Biochem J
, vol.353
, pp. 41-50
-
-
Choi, Y.H.1
Ekholm, D.2
Krall, J.3
Ahmad, F.4
Degerman, E.5
Manganiello, V.C.6
Movsesian, M.A.7
-
34
-
-
0035204531
-
Regulation and function of the cyclic nucleotide phosphodiesterase (PDE3) gene family
-
Shakur Y, Holst L S, Landstrom T R, Movsesian M, Degerman E, Manganiello V. Regulation and function of the cyclic nucleotide phosphodiesterase (PDE3) gene family. Prog Nucleic Acid Res Mol Biol: 2001; 66 241 277
-
(2001)
Prog Nucleic Acid Res Mol Biol
, vol.66
, pp. 241-277
-
-
Shakur, Y.1
Holst, L.S.2
Landstrom, T.R.3
Movsesian, M.4
Degerman, E.5
Manganiello, V.6
-
35
-
-
0031281531
-
Altered Expression of PDE1 and PDE4 Cyclic Nucleotide Phosphodiesterase Isoforms in 7-oxo-prostacyclin-preconditioned Rat Heart
-
Kostic M M, Erdogan S, Rena G, Borchert G, Hoch B, Bartel S, Scotland G, Huston E, Houslay M D, Krause E-G. Altered Expression of PDE1 and PDE4 Cyclic Nucleotide Phosphodiesterase Isoforms in 7-oxo-prostacyclin-preconditioned Rat Heart. J Mol Cell Cardiol: 1997; 29 3135 3146
-
(1997)
J Mol Cell Cardiol
, vol.29
, pp. 3135-3146
-
-
Kostic, M.M.1
Erdogan, S.2
Rena, G.3
Borchert, G.4
Hoch, B.5
Bartel, S.6
Scotland, G.7
Huston, E.8
Houslay, M.D.9
Krause, E.-G.10
-
36
-
-
78649913343
-
Concerted Regulation of cGMP and cAMP Phosphodiesterases in Early Cardiac Hypertrophy Induced by Angiotensin II
-
Mokni W, Keravis T, Etienne-Selloum N, Walter A, Kane M O, Schini-Kerth V B, Lugnier C. Concerted Regulation of cGMP and cAMP Phosphodiesterases in Early Cardiac Hypertrophy Induced by Angiotensin II. PLoS One: 2010; 5 e14227
-
(2010)
PLoS One
, vol.5
-
-
Mokni, W.1
Keravis, T.2
Etienne-Selloum, N.3
Walter, A.4
Kane, M.O.5
Schini-Kerth, V.B.6
Lugnier, C.7
-
37
-
-
79957876717
-
Conserved expression and functions of PDE4 in rodent and human heart
-
Richter W, Xie M, Scheitrum C, Krall J, Movsesian M A, Conti M. Conserved expression and functions of PDE4 in rodent and human heart. Basic Res Cardiol: 2011; 106 249 262
-
(2011)
Basic Res Cardiol
, vol.106
, pp. 249-262
-
-
Richter, W.1
Xie, M.2
Scheitrum, C.3
Krall, J.4
Movsesian, M.A.5
Conti, M.6
-
38
-
-
79959940734
-
Phosphodiesterase 4B in the cardiac L-type Ca2+ channel complex regulates Ca2+ current and protects against ventricular arrhythmias in mice
-
Leroy J, Richter W, Mika D, Castro LR V, Abi-Gerges A, Xie M, Scheitrum C, Lefebvre F, Schittl J, Mateo P, Westenbroek R, Catterall W A, Charpentier F, Conti M, Fischmeister R, Vandecasteele G. Phosphodiesterase 4B in the cardiac L-type Ca2+ channel complex regulates Ca2+ current and protects against ventricular arrhythmias in mice. J Clin Invest: 2011; 121 2651 2661
-
(2011)
J Clin Invest
, vol.121
, pp. 2651-2661
-
-
Leroy, J.1
Richter, W.2
Mika, D.3
Castro, L.R.V.4
Abi-Gerges, A.5
Xie, M.6
Scheitrum, C.7
Lefebvre, F.8
Schittl, J.9
Mateo, P.10
Westenbroek, R.11
Catterall, W.A.12
Charpentier, F.13
Conti, M.14
Fischmeister, R.15
Vandecasteele, G.16
-
39
-
-
0033564377
-
Genomic origin and transcriptional regulation of two variants of cGMP binding cGMP specific phosphodiesterases
-
Kotera J, Fujishige K, Imai Y, Kawai E, Michibata H, Akatsuka H, Yanaka N, Omori K. Genomic origin and transcriptional regulation of two variants of cGMP binding cGMP specific phosphodiesterases. Eur J Biochem: 1999; 262 866 873
-
(1999)
Eur J Biochem
, vol.262
, pp. 866-873
-
-
Kotera, J.1
Fujishige, K.2
Imai, Y.3
Kawai, E.4
Michibata, H.5
Akatsuka, H.6
Yanaka, N.7
Omori, K.8
-
40
-
-
60549098959
-
Ventricular Phosphodiesterase-5 Expression Is Increased in Patients with Advanced Heart Failure and Contributes to Adverse Ventricular Remodeling after Myocardial Infarction in Mice
-
Pokreisz P, Vandenwijngaert S, Bito V, Van den Bergh A, Lenaerts I, Busch C, Marsboom G, Gheysens O, Vermeersch P, Biesmans L, Liu X, Gillijns H, Pellens M, Van Lommel A, Buys E, Schoonjans L, Vanhaecke J, Verbeken E, Sipido K, Herijgers P, Bloch K D, Janssens S P. Ventricular Phosphodiesterase-5 Expression Is Increased in Patients With Advanced Heart Failure and Contributes to Adverse Ventricular Remodeling After Myocardial Infarction in Mice. Circulation: 2009; 119 408 416
-
(2009)
Circulation
, vol.119
, pp. 408-416
-
-
Pokreisz, P.1
Vandenwijngaert, S.2
Bito, V.3
Van Den Bergh, A.4
Lenaerts, I.5
Busch, C.6
Marsboom, G.7
Gheysens, O.8
Vermeersch, P.9
Biesmans, L.10
Liu, X.11
Gillijns, H.12
Pellens, M.13
Van Lommel, A.14
Buys, E.15
Schoonjans, L.16
Vanhaecke, J.17
Verbeken, E.18
Sipido, K.19
Herijgers, P.20
Bloch, K.D.21
Janssens, S.P.22
more..
-
41
-
-
0345708290
-
Sildenafil citrate does not affect cardiac contractility in human or dog heart
-
Corbin J, Rannels S, Neal D, Chang P, Grimes K, Beasley A, Francis S. Sildenafil citrate does not affect cardiac contractility in human or dog heart. Curr Med Res Opin: 2003; 19 747 752
-
(2003)
Curr Med Res Opin
, vol.19
, pp. 747-752
-
-
Corbin, J.1
Rannels, S.2
Neal, D.3
Chang, P.4
Grimes, K.5
Beasley, A.6
Francis, S.7
-
42
-
-
34547611337
-
Phosphodiesterase Type 5 Is Highly Expressed in the Hypertrophied Human Right Ventricle, and Acute Inhibition of Phosphodiesterase Type 5 Improves Contractility
-
Nagendran J, Archer S L, Soliman D, Gurtu V, Moudgil R, Haromy A, St Aubin C, Webster L, Rebeyka I M, Ross D B, Light P E, Dyck JRB, Michelakis E D. Phosphodiesterase Type 5 Is Highly Expressed in the Hypertrophied Human Right Ventricle, and Acute Inhibition of Phosphodiesterase Type 5 Improves Contractility. Circulation: 2007; 116 238 248
-
(2007)
Circulation
, vol.116
, pp. 238-248
-
-
Nagendran, J.1
Archer, S.L.2
Soliman, D.3
Gurtu, V.4
Moudgil, R.5
Haromy, A.6
St Aubin, C.7
Webster, L.8
Rebeyka, I.M.9
Ross, D.B.10
Light, P.E.11
Dyck, J.R.B.12
Michelakis, E.D.13
-
44
-
-
55049140487
-
Expression, Activity, and Pro-Hypertrophic Effects of PDE5A in Cardiac Myocytes
-
Zhang M, Koitabashi N, Nagayama T, Rambaran R, Feng N, Takimoto E, Koenke T, O'Rourke B, Champion H C, Crow M T, Kass D A. Expression, Activity, and Pro-Hypertrophic Effects of PDE5A in Cardiac Myocytes. Cell Signal: 2008; 20 2231 2236
-
(2008)
Cell Signal
, vol.20
, pp. 2231-2236
-
-
Zhang, M.1
Koitabashi, N.2
Nagayama, T.3
Rambaran, R.4
Feng, N.5
Takimoto, E.6
Koenke, T.7
O'Rourke, B.8
Champion, H.C.9
Crow, M.T.10
Kass, D.A.11
-
45
-
-
77950377332
-
Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase i in cardiomyocytes
-
Lukowski R, Rybalkin S D, Loga F, Leiss V, Beavo J A, Hofmann F. Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase I in cardiomyocytes. Proc Natl Acad Sci USA: 2010; 107 5646 5651
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5646-5651
-
-
Lukowski, R.1
Rybalkin, S.D.2
Loga, F.3
Leiss, V.4
Beavo, J.A.5
Hofmann, F.6
-
46
-
-
77953718408
-
Phosphodiesterase 8A (PDE8A) regulates excitation-contraction coupling in ventricular myocytes
-
Patrucco E, Albergine M S, Santana L F, Beavo J A. Phosphodiesterase 8A (PDE8A) regulates excitation-contraction coupling in ventricular myocytes. J Mol Cell Cardiol: 2010; 49 330 333
-
(2010)
J Mol Cell Cardiol
, vol.49
, pp. 330-333
-
-
Patrucco, E.1
Albergine, M.S.2
Santana, L.F.3
Beavo, J.A.4
-
47
-
-
0037436281
-
Identification and distribution of different mRNA variants produced by differential splicing in the human phosphodiesterase 9A gene
-
Rentero C, Monfort A, Puigdomènech P. Identification and distribution of different mRNA variants produced by differential splicing in the human phosphodiesterase 9A gene. Biochem Biophys Res Commun: 2003; 301 686 692
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 686-692
-
-
Rentero, C.1
Monfort, A.2
Puigdomènech, P.3
-
48
-
-
60849083800
-
Phosphodiesterases PDE3 and PDE4 jointly control the inotropic effects but not chronotropic effects of ()-CGP12177 despite PDE4-evoked sinoatrial bradycardia in rat atrium
-
Galindo-Tovar A, Vargas M L, Kaumann A J. Phosphodiesterases PDE3 and PDE4 jointly control the inotropic effects but not chronotropic effects of ()-CGP12177 despite PDE4-evoked sinoatrial bradycardia in rat atrium. Naunyn-Schmied Arch Pharmacol: 2008; 379 379 384
-
(2008)
Naunyn-Schmied Arch Pharmacol
, vol.379
, pp. 379-384
-
-
Galindo-Tovar, A.1
Vargas, M.L.2
Kaumann, A.J.3
-
49
-
-
79959797208
-
Phosphodiesterases reduce spontaneous sinoatrial beating but not the "fight or flighto" tachycardia elicited by agonists through Gs-protein-coupled receptors
-
Kaumann A J. Phosphodiesterases reduce spontaneous sinoatrial beating but not the "fight or flighto" tachycardia elicited by agonists through Gs-protein-coupled receptors. Trends Pharmacol Sci: 2011; 32 377 383
-
(2011)
Trends Pharmacol Sci
, vol.32
, pp. 377-383
-
-
Kaumann, A.J.1
-
50
-
-
0025782740
-
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP
-
DiFrancesco D, Tortora P. Direct activation of cardiac pacemaker channels by intracellular cyclic AMP. Nature: 1991; 351 145 147
-
(1991)
Nature
, vol.351
, pp. 145-147
-
-
Difrancesco, D.1
Tortora, P.2
-
51
-
-
67749116532
-
Control of heart rate by cAMP sensitivity of HCN channels
-
Alig J, Marger L, Mesirca P, Ehmke H, Mangoni M E, Isbrandt D. Control of heart rate by cAMP sensitivity of HCN channels. Proc Natl Acad Sci USA: 2009; 106 12189 12194
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 12189-12194
-
-
Alig, J.1
Marger, L.2
Mesirca, P.3
Ehmke, H.4
Mangoni, M.E.5
Isbrandt, D.6
-
52
-
-
39449129669
-
Phosphodiesterase 4 blunts inotropism and arrhythmias but not sinoatrial tachycardia of (-)-adrenaline mediated through mouse cardiac β1adrenoceptors
-
Galindo Tovar A, Kaumann A J. Phosphodiesterase 4 blunts inotropism and arrhythmias but not sinoatrial tachycardia of (-)-adrenaline mediated through mouse cardiac β1adrenoceptors. Br J Pharmacol: 2008; 153 710 720
-
(2008)
Br J Pharmacol
, vol.153
, pp. 710-720
-
-
Galindo Tovar, A.1
Kaumann, A.J.2
-
53
-
-
77953535360
-
Function of cardiac [beta]1- and [beta]2-adrenoceptors of newborn piglets: Role of phosphodiesterases PDE3 and PDE4
-
Galindo-Tovar A, Vargas M L, Kaumann A J. Function of cardiac [beta]1- and [beta]2-adrenoceptors of newborn piglets: Role of phosphodiesterases PDE3 and PDE4. Eur J Pharmacol: 2010; 638 99 107
-
(2010)
Eur J Pharmacol
, vol.638
, pp. 99-107
-
-
Galindo-Tovar, A.1
Vargas, M.L.2
Kaumann, A.J.3
-
54
-
-
60849115027
-
Inotropy and L-type Ca2+ current, activated by β1- and β2-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heart
-
Christ T, Galindo-Tovar A, Thoms M, Ravens U, Kaumann A J. Inotropy and L-type Ca2+ current, activated by β1- and β2-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heart. Br J Pharmacol: 2009; 156 62 83
-
(2009)
Br J Pharmacol
, vol.156
, pp. 62-83
-
-
Christ, T.1
Galindo-Tovar, A.2
Thoms, M.3
Ravens, U.4
Kaumann, A.J.5
-
55
-
-
33947494913
-
Regulation of Phosphodiesterase 3 and Inducible cAMP Early Repressor in the Heart
-
Yan C, Miller C L, Abe J. Regulation of Phosphodiesterase 3 and Inducible cAMP Early Repressor in the Heart. Circ Res: 2007; 100 489 501
-
(2007)
Circ Res
, vol.100
, pp. 489-501
-
-
Yan, C.1
Miller, C.L.2
Abe, J.3
-
56
-
-
0346334593
-
PDE3 inhibition in dilated cardiomyopathy: Reasons to reconsider
-
Matthew A M. PDE3 inhibition in dilated cardiomyopathy: reasons to reconsider. J Card Fail: 2003; 9 475 480
-
(2003)
J Card Fail
, vol.9
, pp. 475-480
-
-
Matthew, A.M.1
-
57
-
-
79952000271
-
The Large Isoforms of A-Kinase Anchoring Protein 18 Mediate the Phosphorylation of Inhibitor-1 by Protein Kinase A and the Inhibition of Protein Phosphatase 1 Activity
-
Singh A, Redden J M, Kapiloff M S, Dodge-Kafka K L. The Large Isoforms of A-Kinase Anchoring Protein 18 Mediate the Phosphorylation of Inhibitor-1 by Protein Kinase A and the Inhibition of Protein Phosphatase 1 Activity. Mol Pharmacol: 2011; 79 533 540
-
(2011)
Mol Pharmacol
, vol.79
, pp. 533-540
-
-
Singh, A.1
Redden, J.M.2
Kapiloff, M.S.3
Dodge-Kafka, K.L.4
-
58
-
-
0037092333
-
Role of cyclic GMP-dependent protein kinase in the contractile response to exogenous nitric oxide in rat cardiac myocytes
-
Layland J, Li J-M, Shah A M. Role of cyclic GMP-dependent protein kinase in the contractile response to exogenous nitric oxide in rat cardiac myocytes. J Physiol: 2002; 540 457 467
-
(2002)
J Physiol
, vol.540
, pp. 457-467
-
-
Layland, J.1
Li, J.-M.2
Shah, A.M.3
-
59
-
-
34548363796
-
Protein kinase G phosphorylates Cav1.2 alpha1c and beta2 subunits
-
Yang L, Liu G, Zakharov S I, Bellinger A M, Mongillo M, Marx S O. Protein kinase G phosphorylates Cav1.2 alpha1c and beta2 subunits. Circ Res: 2007; 101 465 474
-
(2007)
Circ Res
, vol.101
, pp. 465-474
-
-
Yang, L.1
Liu, G.2
Zakharov, S.I.3
Bellinger, A.M.4
Mongillo, M.5
Marx, S.O.6
-
60
-
-
0035395093
-
Local response of L-type Ca(2+) current to nitric oxide in frog ventricular myocytes
-
Dittrich M, Jurevicius J, Georget M, Rochais F, Fleischmann B, Hescheler J, Fischmeister R. Local response of L-type Ca(2+) current to nitric oxide in frog ventricular myocytes. J Physiol (Lond): 2001; 534 109 121
-
(2001)
J Physiol (Lond)
, vol.534
, pp. 109-121
-
-
Dittrich, M.1
Jurevicius, J.2
Georget, M.3
Rochais, F.4
Fleischmann, B.5
Hescheler, J.6
Fischmeister, R.7
-
61
-
-
0030958762
-
CGMP-stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes
-
Rivet-Bastide M, Vandecasteele G, Hatem S, Verde I, Bénardeau A, Mercadier J J, Fischmeister R. cGMP-stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes. J Clin Invest: 1997; 99 2710 2718
-
(1997)
J Clin Invest
, vol.99
, pp. 2710-2718
-
-
Rivet-Bastide, M.1
Vandecasteele, G.2
Hatem, S.3
Verde, I.4
Bénardeau, A.5
Mercadier, J.J.6
Fischmeister, R.7
-
62
-
-
0025924817
-
Ca2+ current is regulated by cyclic GMP-dependent protein kinase in mammalian cardiac myocytes
-
Méry P F, Lohmann S M, Walter U, Fischmeister R. Ca2+ current is regulated by cyclic GMP-dependent protein kinase in mammalian cardiac myocytes. Proc Natl Acad Sci USA: 1991; 88 1197 1201
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 1197-1201
-
-
Méry, P.F.1
Lohmann, S.M.2
Walter, U.3
Fischmeister, R.4
-
63
-
-
26644447370
-
Species- and tissue-dependent effects of NO and cyclic GMP on cardiac ion channels
-
Fischmeister R, Castro L, Abi-Gerges A, Rochais F, Vandecasteele G. Species- and tissue-dependent effects of NO and cyclic GMP on cardiac ion channels. Comp Biochem Physiol Part A: Mol Integ Physiol: 2005; 142 136 143
-
(2005)
Comp Biochem Physiol Part A: Mol Integ Physiol
, vol.142
, pp. 136-143
-
-
Fischmeister, R.1
Castro, L.2
Abi-Gerges, A.3
Rochais, F.4
Vandecasteele, G.5
-
64
-
-
0035368737
-
Cyclic GMP regulation of the L-type Ca2+ channel current in human atrial myocytes
-
Vandecasteele G, Verde I, Rücker-Martin C, Donzeau-Gouge P, Fischmeister R. Cyclic GMP regulation of the L-type Ca2+ channel current in human atrial myocytes. J Physiol: 2001; 533 329 340
-
(2001)
J Physiol
, vol.533
, pp. 329-340
-
-
Vandecasteele, G.1
Verde, I.2
Rücker-Martin, C.3
Donzeau-Gouge, P.4
Fischmeister, R.5
-
65
-
-
33644865929
-
Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway
-
Mongillo M, Tocchetti C G, Terrin A, Lissandron V, Cheung Y-F, Dostmann W R, Pozzan T, Kass D A, Paolocci N, Houslay M D, Zaccolo M. Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway. Circ Res: 2006; 98 226 234
-
(2006)
Circ Res
, vol.98
, pp. 226-234
-
-
Mongillo, M.1
Tocchetti, C.G.2
Terrin, A.3
Lissandron, V.4
Cheung, Y.-F.5
Dostmann, W.R.6
Pozzan, T.7
Kass, D.A.8
Paolocci, N.9
Houslay, M.D.10
Zaccolo, M.11
-
66
-
-
34547959389
-
PI3Kγ Is Required for PDE4, not PDE3, Activity in Subcellular Microdomains Containing the Sarcoplasmic Reticular Calcium ATPase in Cardiomyocytes
-
Kerfant B-G, Zhao D, Lorenzen-Schmidt I, Wilson L S, Cai S, Chen SR W, Maurice D H, Backx P H. PI3Kγ Is Required for PDE4, not PDE3, Activity in Subcellular Microdomains Containing the Sarcoplasmic Reticular Calcium ATPase in Cardiomyocytes. Circ Res: 2007; 101 400 408
-
(2007)
Circ Res
, vol.101
, pp. 400-408
-
-
Kerfant, B.-G.1
Zhao, D.2
Lorenzen-Schmidt, I.3
Wilson, L.S.4
Cai, S.5
Chen, S.R.W.6
Maurice, D.H.7
Backx, P.H.8
-
67
-
-
0026072848
-
Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group
-
Packer M, Carver J R, Rodeheffer R J, Ivanhoe R J, DiBianco R, Zeldis S M, Hendrix G H, Bommer W J, Elkayam U, Kukin M L. Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group. N Engl J Med: 1991; 325 1468 1475
-
(1991)
N Engl J Med
, vol.325
, pp. 1468-1475
-
-
Packer, M.1
Carver, J.R.2
Rodeheffer, R.J.3
Ivanhoe, R.J.4
Dibianco, R.5
Zeldis, S.M.6
Hendrix, G.H.7
Bommer, W.J.8
Elkayam, U.9
Kukin, M.L.10
-
68
-
-
4344714889
-
PI3K[gamma] Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects
-
Patrucco E, Notte A, Barberis L, Selvetella G, Maffei A, Brancaccio M, Marengo S, Russo G, Azzolino O, Rybalkin S D, Silengo L, Altruda F, Wetzker R, Wymann M P, Lembo G, Hirsch E. PI3K[gamma] Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects. Cell: 2004; 118 375 387
-
(2004)
Cell
, vol.118
, pp. 375-387
-
-
Patrucco, E.1
Notte, A.2
Barberis, L.3
Selvetella, G.4
Maffei, A.5
Brancaccio, M.6
Marengo, S.7
Russo, G.8
Azzolino, O.9
Rybalkin, S.D.10
Silengo, L.11
Altruda, F.12
Wetzker, R.13
Wymann, M.P.14
Lembo, G.15
Hirsch, E.16
-
69
-
-
71749107983
-
Differential association of phosphodiesterase 4D isoforms with beta2-adrenoceptor in cardiac myocytes
-
De Arcangelis V, Liu R, Soto D, Xiang Y. Differential association of phosphodiesterase 4D isoforms with beta2-adrenoceptor in cardiac myocytes. J Biol Chem: 2009; 284 33824 33832
-
(2009)
J Biol Chem
, vol.284
, pp. 33824-33832
-
-
De Arcangelis, V.1
Liu, R.2
Soto, D.3
Xiang, Y.4
-
70
-
-
0037417890
-
Beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi
-
Baillie G S, Sood A, McPhee I, Gall I, Perry S J, Lefkowitz R J, Houslay M D. beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi. Proc Natl Acad Sci USA: 2003; 100 940 945
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 940-945
-
-
Baillie, G.S.1
Sood, A.2
McPhee, I.3
Gall, I.4
Perry, S.J.5
Lefkowitz, R.J.6
Houslay, M.D.7
-
71
-
-
38549107922
-
Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4
-
Richter W, Day P, Agrawal R, Bruss M D, Granier S, Wang Y L, Rasmussen SG F, Horner K, Wang P, Lei T, Patterson A J, Kobilka B, Conti M. Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4. EMBO J: 2008; 27 384 393
-
(2008)
EMBO J
, vol.27
, pp. 384-393
-
-
Richter, W.1
Day, P.2
Agrawal, R.3
Bruss, M.D.4
Granier, S.5
Wang, Y.L.6
Rasmussen, S.G.F.7
Horner, K.8
Wang, P.9
Lei, T.10
Patterson, A.J.11
Kobilka, B.12
Conti, M.13
-
72
-
-
26244467287
-
Phosphodiesterase 4D Deficiency in the Ryanodine-Receptor Complex Promotes Heart Failure and Arrhythmias
-
Lehnart S E, Wehrens XH T, Reiken S, Warrier S, Belevych A E, Harvey R D, Richter W, Jin S-LC, Conti M, Marks A R. Phosphodiesterase 4D Deficiency in the Ryanodine-Receptor Complex Promotes Heart Failure and Arrhythmias. Cell: 2005; 123 25 35
-
(2005)
Cell
, vol.123
, pp. 25-35
-
-
Lehnart, S.E.1
Wehrens, X.H.T.2
Reiken, S.3
Warrier, S.4
Belevych, A.E.5
Harvey, R.D.6
Richter, W.7
Jin, S.-L.8
Conti, M.9
Marks, A.R.10
-
73
-
-
80054995738
-
Phosphodiesterase 4D Regulates Baseline Sarcoplasmic Reticulum Ca2+ Release and Cardiac Contractility, Independently of L-Type Ca2+ Current
-
Beca S, Helli P B, Simpson J A, Zhao D, Farman G P, Jones P, Tian X, Wilson L S, Ahmad F, Chen SR W, Movsesian M A, Manganiello V, Maurice D H, Conti M, Backx P H. Phosphodiesterase 4D Regulates Baseline Sarcoplasmic Reticulum Ca2+ Release and Cardiac Contractility, Independently of L-Type Ca2+ Current. Circ Res: 2011; 109 1024 1030
-
(2011)
Circ Res
, vol.109
, pp. 1024-1030
-
-
Beca, S.1
Helli, P.B.2
Simpson, J.A.3
Zhao, D.4
Farman, G.P.5
Jones, P.6
Tian, X.7
Wilson, L.S.8
Ahmad, F.9
Chen, S.R.W.10
Movsesian, M.A.11
Manganiello, V.12
Maurice, D.H.13
Conti, M.14
Backx, P.H.15
-
74
-
-
34247488713
-
Compartmentalization of Cardiac β-Adrenergic Inotropy Modulation by Phosphodiesterase Type 5
-
Takimoto E, Belardi D, Tocchetti C G, Vahebi S, Cormaci G, Ketner E A, Moens A L, Champion H C, Kass D A. Compartmentalization of Cardiac β-Adrenergic Inotropy Modulation by Phosphodiesterase Type 5. Circulation: 2007; 115 2159 2167
-
(2007)
Circulation
, vol.115
, pp. 2159-2167
-
-
Takimoto, E.1
Belardi, D.2
Tocchetti, C.G.3
Vahebi, S.4
Cormaci, G.5
Ketner, E.A.6
Moens, A.L.7
Champion, H.C.8
Kass, D.A.9
-
75
-
-
27444439573
-
Sildenafil Inhibits β-Adrenergic-Stimulated Cardiac Contractility in Humans
-
Borlaug B A, Melenovsky V, Marhin T, Fitzgerald P, Kass D A. Sildenafil Inhibits β-Adrenergic-Stimulated Cardiac Contractility in Humans. Circulation: 2005; 112 2642 2649
-
(2005)
Circulation
, vol.112
, pp. 2642-2649
-
-
Borlaug, B.A.1
Melenovsky, V.2
Marhin, T.3
Fitzgerald, P.4
Kass, D.A.5
-
76
-
-
19944428363
-
CGMP Catabolism by Phosphodiesterase 5A Regulates Cardiac Adrenergic Stimulation by NOS3-Dependent Mechanism
-
Takimoto E, Champion H C, Belardi D, Moslehi J, Mongillo M, Mergia E, Montrose D C, Isoda T, Aufiero K, Zaccolo M, Dostmann W R, Smith C J, Kass D A. cGMP Catabolism by Phosphodiesterase 5A Regulates Cardiac Adrenergic Stimulation by NOS3-Dependent Mechanism. Circ Res: 2005; 96 100 109
-
(2005)
Circ Res
, vol.96
, pp. 100-109
-
-
Takimoto, E.1
Champion, H.C.2
Belardi, D.3
Moslehi, J.4
Mongillo, M.5
Mergia, E.6
Montrose, D.C.7
Isoda, T.8
Aufiero, K.9
Zaccolo, M.10
Dostmann, W.R.11
Smith, C.J.12
Kass, D.A.13
-
77
-
-
21044453725
-
Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: Implication in heart failure
-
Ding B, Abe J, Wei H, Huang Q, Walsh R A, Molina C A, Zhao A, Sadoshima J, Blaxall B C, Berk B C, Yan C. Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure. Circulation: 2005; 111 2469 2476
-
(2005)
Circulation
, vol.111
, pp. 2469-2476
-
-
Ding, B.1
Abe, J.2
Wei, H.3
Huang, Q.4
Walsh, R.A.5
Molina, C.A.6
Zhao, A.7
Sadoshima, J.8
Blaxall, B.C.9
Berk, B.C.10
Yan, C.11
-
78
-
-
79955664087
-
Mammalian Cyclic Nucleotide Phosphodiesterases: Molecular Mechanisms and Physiological Functions
-
Francis S H, Blount M A, Corbin J D. Mammalian Cyclic Nucleotide Phosphodiesterases: Molecular Mechanisms and Physiological Functions. Physiol Rev: 2011; 91 651 690
-
(2011)
Physiol Rev
, vol.91
, pp. 651-690
-
-
Francis, S.H.1
Blount, M.A.2
Corbin, J.D.3
-
79
-
-
33947534858
-
Activation of Extracellular Signal-Regulated Kinase 5 Reduces Cardiac Apoptosis and Dysfunction via Inhibition of a Phosphodiesterase 3A/Inducible cAMP Early Repressor Feedback Loop
-
Yan C, Ding B, Shishido T, Woo C-H, Itoh S, Jeon K-I, Liu W, Xu H, McClain C, Molina C A, Blaxall B C, Abe J. Activation of Extracellular Signal-Regulated Kinase 5 Reduces Cardiac Apoptosis and Dysfunction via Inhibition of a Phosphodiesterase 3A/Inducible cAMP Early Repressor Feedback Loop. Circ Res: 2007; 100 510 519
-
(2007)
Circ Res
, vol.100
, pp. 510-519
-
-
Yan, C.1
Ding, B.2
Shishido, T.3
Woo, C.-H.4
Itoh, S.5
Jeon, K.-I.6
Liu, W.7
Xu, H.8
McClain, C.9
Molina, C.A.10
Blaxall, B.C.11
Abe, J.12
-
80
-
-
70350133628
-
Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals
-
Abi-Gerges A, Richter W, Lefebvre F, Mateo P, Varin A, Heymes C, Samuel J-L, Lugnier C, Conti M, Fischmeister R, Vandecasteele G. Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals. Circ Res: 2009; 105 784 792
-
(2009)
Circ Res
, vol.105
, pp. 784-792
-
-
Abi-Gerges, A.1
Richter, W.2
Lefebvre, F.3
Mateo, P.4
Varin, A.5
Heymes, C.6
Samuel, J.-L.7
Lugnier, C.8
Conti, M.9
Fischmeister, R.10
Vandecasteele, G.11
-
81
-
-
58149164894
-
Interventional effect of valsartan on expression of inducible cAMP early repressor and phosphodiesterase 3A in rats after myocardial infarction
-
Ma D, Fu L, Shen J, Zhou P, Gao Y, Xie R, Li Y, Han Y, Wang Y, Wang F. Interventional effect of valsartan on expression of inducible cAMP early repressor and phosphodiesterase 3A in rats after myocardial infarction. Eur J Pharmacol: 2009; 602 348 354
-
(2009)
Eur J Pharmacol
, vol.602
, pp. 348-354
-
-
Ma, D.1
Fu, L.2
Shen, J.3
Zhou, P.4
Gao, Y.5
Xie, R.6
Li, Y.7
Han, Y.8
Wang, Y.9
Wang, F.10
-
82
-
-
0025886685
-
Effects of zaprinast and rolipram on platelet aggregation and arrhythmias following myocardial ischaemia and reperfusion in anaesthetized rabbits
-
Holbrook M, Coker S J. Effects of zaprinast and rolipram on platelet aggregation and arrhythmias following myocardial ischaemia and reperfusion in anaesthetized rabbits. Br J Pharmacol: 1991; 103 1973 1979
-
(1991)
Br J Pharmacol
, vol.103
, pp. 1973-1979
-
-
Holbrook, M.1
Coker, S.J.2
-
83
-
-
0034640113
-
PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
-
Marx S O, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks A R. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell: 2000; 101 365 376
-
(2000)
Cell
, vol.101
, pp. 365-376
-
-
Marx, S.O.1
Reiken, S.2
Hisamatsu, Y.3
Jayaraman, T.4
Burkhoff, D.5
Rosemblit, N.6
Marks, A.R.7
-
84
-
-
0037708928
-
FKBP12.6 Deficiency and Defective Calcium Release Channel (Ryanodine Receptor) Function Linked to Exercise-Induced Sudden Cardiac Death
-
Wehrens XH T, Lehnart S E, Huang F, Vest J A, Reiken S R, Mohler P J, Sun J, Guatimosim S, Song L-S, Rosemblit N, D'Armiento J M, Napolitano C, Memmi M, Priori S G, Lederer W J, Marks A R. FKBP12.6 Deficiency and Defective Calcium Release Channel (Ryanodine Receptor) Function Linked to Exercise-Induced Sudden Cardiac Death. Cell: 2003; 113 829 840
-
(2003)
Cell
, vol.113
, pp. 829-840
-
-
Wehrens, X.H.T.1
Lehnart, S.E.2
Huang, F.3
Vest, J.A.4
Reiken, S.R.5
Mohler, P.J.6
Sun, J.7
Guatimosim, S.8
Song, L.-S.9
Rosemblit, N.10
D'Armiento, J.M.11
Napolitano, C.12
Memmi, M.13
Priori, S.G.14
Lederer, W.J.15
Marks, A.R.16
-
85
-
-
0034640113
-
PKA Phosphorylation Dissociates FKBP12.6 from the Calcium Release Channel (Ryanodine Receptor): Defective Regulation in Failing Hearts
-
Marx S O, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks A R. PKA Phosphorylation Dissociates FKBP12.6 from the Calcium Release Channel (Ryanodine Receptor): Defective Regulation in Failing Hearts. Cell: 2000; 101 365 376
-
(2000)
Cell
, vol.101
, pp. 365-376
-
-
Marx, S.O.1
Reiken, S.2
Hisamatsu, Y.3
Jayaraman, T.4
Burkhoff, D.5
Rosemblit, N.6
Marks, A.R.7
-
86
-
-
84861917647
-
Cyclic Adenosine Monophosphate Phosphodiesterase Type 4 Protects Against Atrial Arrhythmias
-
Molina C E, Leroy J, Richter W, Xie M, Scheitrum C, Lee I-O, Maack C, Rucker-Martin C, Donzeau-Gouge P, Verde I, Llach A, Hove-Madsen L, Conti M, Vandecasteele G, Fischmeister R. Cyclic Adenosine Monophosphate Phosphodiesterase Type 4 Protects Against Atrial Arrhythmias. J Am Coll Cardiol: 2012; 59 2182 2190
-
(2012)
J Am Coll Cardiol
, vol.59
, pp. 2182-2190
-
-
Molina, C.E.1
Leroy, J.2
Richter, W.3
Xie, M.4
Scheitrum, C.5
Lee, I.-O.6
Maack, C.7
Rucker-Martin, C.8
Donzeau-Gouge, P.9
Verde, I.10
Llach, A.11
Hove-Madsen, L.12
Conti, M.13
Vandecasteele, G.14
Fischmeister, R.15
-
87
-
-
70349085833
-
CGMP-Hydrolytic Activity and Its Inhibition by Sildenafil in Normal and Failing Human and Mouse Myocardium
-
Vandeput F, Krall J, Ockaili R, Salloum F N, Florio V, Corbin J D, Francis S H, Kukreja R C, Movsesian M A. cGMP-Hydrolytic Activity and Its Inhibition by Sildenafil in Normal and Failing Human and Mouse Myocardium. J Pharmacol Exp Therap: 2009; 330 884 891
-
(2009)
J Pharmacol Exp Therap
, vol.330
, pp. 884-891
-
-
Vandeput, F.1
Krall, J.2
Ockaili, R.3
Salloum, F.N.4
Florio, V.5
Corbin, J.D.6
Francis, S.H.7
Kukreja, R.C.8
Movsesian, M.A.9
-
88
-
-
1042298055
-
Cardioprotection with phosphodiesterase-5 inhibition - A novel preconditioning strategy
-
Kukreja R C, Ockaili R, Salloum F, Yin C, Hawkins J, Das A, Xi L. Cardioprotection with phosphodiesterase-5 inhibition - a novel preconditioning strategy. J Mol Cell Cardiol: 2004; 36 165 173
-
(2004)
J Mol Cell Cardiol
, vol.36
, pp. 165-173
-
-
Kukreja, R.C.1
Ockaili, R.2
Salloum, F.3
Yin, C.4
Hawkins, J.5
Das, A.6
Xi, L.7
-
89
-
-
17144405644
-
Phosphodiesterase-5 Inhibition with Sildenafil Attenuates Cardiomyocyte Apoptosis and Left Ventricular Dysfunction in a Chronic Model of Doxorubicin Cardiotoxicity
-
Fisher P W, Salloum F, Das A, Hyder H, Kukreja R C. Phosphodiesterase-5 Inhibition With Sildenafil Attenuates Cardiomyocyte Apoptosis and Left Ventricular Dysfunction in a Chronic Model of Doxorubicin Cardiotoxicity. Circulation: 2005; 111 1601 1610
-
(2005)
Circulation
, vol.111
, pp. 1601-1610
-
-
Fisher, P.W.1
Salloum, F.2
Das, A.3
Hyder, H.4
Kukreja, R.C.5
-
90
-
-
20044363270
-
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
-
Takimoto E, Champion H C, Li M, Belardi D, Ren S, Rodriguez E R, Bedja D, Gabrielson K L, Wang Y, Kass D A. Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nat Med: 2005; 11 214 222
-
(2005)
Nat Med
, vol.11
, pp. 214-222
-
-
Takimoto, E.1
Champion, H.C.2
Li, M.3
Belardi, D.4
Ren, S.5
Rodriguez, E.R.6
Bedja, D.7
Gabrielson, K.L.8
Wang, Y.9
Kass, D.A.10
-
91
-
-
16844382827
-
Phosphodiesterase-5 Inhibitor Sildenafil Preconditions Adult Cardiac Myocytes against Necrosis and Apoptosis
-
Das A, Xi L, Kukreja R C. Phosphodiesterase-5 Inhibitor Sildenafil Preconditions Adult Cardiac Myocytes against Necrosis and Apoptosis. J Biol Chem: 2005; 280 12944 12955
-
(2005)
J Biol Chem
, vol.280
, pp. 12944-12955
-
-
Das, A.1
Xi, L.2
Kukreja, R.C.3
-
92
-
-
77949274491
-
Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition
-
Koitabashi N, Aiba T, Hesketh G G, Rowell J, Zhang M, Takimoto E, Tomaselli G F, Kass D A. Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition. J Mol Cell Cardiol: 2010; 48 713 724
-
(2010)
J Mol Cell Cardiol
, vol.48
, pp. 713-724
-
-
Koitabashi, N.1
Aiba, T.2
Hesketh, G.G.3
Rowell, J.4
Zhang, M.5
Takimoto, E.6
Tomaselli, G.F.7
Kass, D.A.8
-
93
-
-
0031856747
-
Effect of atrial natriuretic peptide and cyclic GMP phosphodiesterase inhibition on collagen synthesis by adult cardiac fibroblasts
-
Redondo J, Bishop J E, Wilkins M R. Effect of atrial natriuretic peptide and cyclic GMP phosphodiesterase inhibition on collagen synthesis by adult cardiac fibroblasts. Br J Pharmacol: 1998; 124 1455 1462
-
(1998)
Br J Pharmacol
, vol.124
, pp. 1455-1462
-
-
Redondo, J.1
Bishop, J.E.2
Wilkins, M.R.3
-
94
-
-
78649715496
-
Myocardial Remodeling Is Controlled by Myocyte-Targeted Gene Regulation of Phosphodiesterase Type 5
-
Zhang M, Takimoto E, Hsu S, Lee D I, Nagayama T, Danner T, Koitabashi N, Barth A S, Bedja D, Gabrielson K L, Wang Y, Kass D A. Myocardial Remodeling Is Controlled by Myocyte-Targeted Gene Regulation of Phosphodiesterase Type 5. J Am Coll Cardiol: 2010; 56 2021 2030
-
(2010)
J Am Coll Cardiol
, vol.56
, pp. 2021-2030
-
-
Zhang, M.1
Takimoto, E.2
Hsu, S.3
Lee, D.I.4
Nagayama, T.5
Danner, T.6
Koitabashi, N.7
Barth, A.S.8
Bedja, D.9
Gabrielson, K.L.10
Wang, Y.11
Kass, D.A.12
-
95
-
-
57649155045
-
Protein Kinase G-dependent Cardioprotective Mechanism of Phosphodiesterase-5 Inhibition Involves Phosphorylation of ERK and GSK3β
-
Das A, Xi L, Kukreja R C. Protein Kinase G-dependent Cardioprotective Mechanism of Phosphodiesterase-5 Inhibition Involves Phosphorylation of ERK and GSK3β J Biol Chem: 2008; 283 29572 29585
-
(2008)
J Biol Chem
, vol.283
, pp. 29572-29585
-
-
Das, A.1
Xi, L.2
Kukreja, R.C.3
-
96
-
-
61749089404
-
Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice
-
Takimoto E, Koitabashi N, Hsu S, Ketner E A, Zhang M, Nagayama T, Bedja D, Gabrielson K L, Blanton R, Siderovski D P, Mendelsohn M E, Kass D A. Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice. J Clin Invest: 2009; 119 408 420
-
(2009)
J Clin Invest
, vol.119
, pp. 408-420
-
-
Takimoto, E.1
Koitabashi, N.2
Hsu, S.3
Ketner, E.A.4
Zhang, M.5
Nagayama, T.6
Bedja, D.7
Gabrielson, K.L.8
Blanton, R.9
Siderovski, D.P.10
Mendelsohn, M.E.11
Kass, D.A.12
-
97
-
-
79955645576
-
RGS2 is a primary terminator of [beta]2-adrenergic receptor-mediated Gi signaling
-
Chakir K, Zhu W, Tsang S, Woo AY-H, Yang D, Wang X, Zeng X, Rhee M-H, Mende U, Koitabashi N, Takimoto E, Blumer K J, Lakatta E G, Kass D A, Xiao R-P. RGS2 is a primary terminator of [beta]2-adrenergic receptor-mediated Gi signaling. J Mol Cell Cardiol: 2011; 50 1000 1007
-
(2011)
J Mol Cell Cardiol
, vol.50
, pp. 1000-1007
-
-
Chakir, K.1
Zhu, W.2
Tsang, S.3
Woo, A.-H.4
Yang, D.5
Wang, X.6
Zeng, X.7
Rhee, M.-H.8
Mende, U.9
Koitabashi, N.10
Takimoto, E.11
Blumer, K.J.12
Lakatta, E.G.13
Kass, D.A.14
Xiao, R.-P.15
-
98
-
-
84860536418
-
Stress-Dependent Dilated Cardiomyopathy in Mice with Cardiomyocyte- Restricted Inactivation of Cyclic GMP-Dependent Protein Kinase i
-
Dec [Epub ahead of print]
-
Frantz S, Klaiber M, Baba H A, Oberwinkler H, Völker K, Ganer B, Bayer B, Abeer M, Schuh K, Feil R, Hofmann F, Kuhn M. Stress-Dependent Dilated Cardiomyopathy in Mice with Cardiomyocyte-Restricted Inactivation of Cyclic GMP-Dependent Protein Kinase I. Eur Heart J Dec: 2011; [Epub ahead of print]. Available from: http://eurheartj.oxfordjournals.org/content/early/2011/12/23/ eurheartj.ehr445
-
(2011)
Eur Heart J
-
-
Frantz, S.1
Klaiber, M.2
Baba, H.A.3
Oberwinkler, H.4
Völker, K.5
Ganer, B.6
Bayer, B.7
Abeer, M.8
Schuh, K.9
Feil, R.10
Hofmann, F.11
Kuhn, M.12
-
99
-
-
0020605971
-
Evaluation of a new bipyridine inotropic agent - Milrinone - in patients with severe congestive heart failure
-
Baim D S, McDowell A V, Cherniles J, Monrad E S, Parker J A, Edelson J, Braunwald E, Grossman W. Evaluation of a new bipyridine inotropic agent - milrinone - in patients with severe congestive heart failure. N Engl J Med: 1983; 309 748 756
-
(1983)
N Engl J Med
, vol.309
, pp. 748-756
-
-
Baim, D.S.1
McDowell, A.V.2
Cherniles, J.3
Monrad, E.S.4
Parker, J.A.5
Edelson, J.6
Braunwald, E.7
Grossman, W.8
-
100
-
-
0022001187
-
Positive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure. Dose-response relationships and comparison to nitroprusside
-
Jaski B E, Fifer M A, Wright R F, Braunwald E, Colucci W S. Positive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure. Dose-response relationships and comparison to nitroprusside. J Clin Invest: 1985; 75 643 649
-
(1985)
J Clin Invest
, vol.75
, pp. 643-649
-
-
Jaski, B.E.1
Fifer, M.A.2
Wright, R.F.3
Braunwald, E.4
Colucci, W.S.5
-
101
-
-
18944403004
-
-
The Cochrane Collaboration Nony P. (ed.). Cochrane Database of Systematic Reviews Chichester, UK Wiley
-
Amsallem E, Kasparian C, Haddour G, Boissel J-P, Nony P. Phosphodiesterase III inhibitors for heart failure. In: The Cochrane Collaboration Nony P. (ed.). Cochrane Database of Systematic Reviews. Chichester, UK Wiley: 2005
-
(2005)
Phosphodiesterase III Inhibitors for Heart Failure
-
-
Amsallem, E.1
Kasparian, C.2
Haddour, G.3
Boissel, J.-P.4
Nony, P.5
-
102
-
-
0036850315
-
Inhibitors of cyclic nucleotide phosphodiesterase PDE3 as adjunct therapy for dilated cardiomyopathy
-
Movsesian M A, Alharethi R. Inhibitors of cyclic nucleotide phosphodiesterase PDE3 as adjunct therapy for dilated cardiomyopathy. Expert Opin Investig Drugs: 2002; 11 1529 1536
-
(2002)
Expert Opin Investig Drugs
, vol.11
, pp. 1529-1536
-
-
Movsesian, M.A.1
Alharethi, R.2
-
103
-
-
0037181515
-
Short-Term Intravenous Milrinone for Acute Exacerbation of Chronic Heart Failure A Randomized Controlled Trial
-
Cuffe M S, Califf R M, Adams K F, Benza R, Bourge R, Colucci W S, Massie B M, O'Connor C M, Pina I, Quigg R, Silver M A, Gheorghiade M. Short-Term Intravenous Milrinone for Acute Exacerbation of Chronic Heart Failure A Randomized Controlled Trial. JAMA: 2002; 287 1541 1547
-
(2002)
JAMA
, vol.287
, pp. 1541-1547
-
-
Cuffe, M.S.1
Califf, R.M.2
Adams, K.F.3
Benza, R.4
Bourge, R.5
Colucci, W.S.6
Massie, B.M.7
O'Connor, C.M.8
Pina, I.9
Quigg, R.10
Silver, M.A.11
Gheorghiade, M.12
-
104
-
-
56449093105
-
The Use of Continuous Milrinone Therapy as Bridge to Transplant Is Safe in Patients with Short Waiting Times
-
Assad-Kottner C, Chen D, Jahanyar J, Cordova F, Summers N, Loebe M, Merla R, Youker K, Torre-Amione G. The Use of Continuous Milrinone Therapy as Bridge to Transplant Is Safe in Patients With Short Waiting Times. J Card Fail: 2008; 14 839 843
-
(2008)
J Card Fail
, vol.14
, pp. 839-843
-
-
Assad-Kottner, C.1
Chen, D.2
Jahanyar, J.3
Cordova, F.4
Summers, N.5
Loebe, M.6
Merla, R.7
Youker, K.8
Torre-Amione, G.9
-
105
-
-
0033935311
-
Milrinone for long-term pharmacologic support of the status 1 heart transplant candidates
-
Canver C C, Chanda J. Milrinone for long-term pharmacologic support of the status 1 heart transplant candidates. Ann Thor Surg: 2000; 69 1823 1826
-
(2000)
Ann Thor Surg
, vol.69
, pp. 1823-1826
-
-
Canver, C.C.1
Chanda, J.2
-
106
-
-
0037603310
-
Cilostazol: A review of its use in intermittent claudication
-
Chapman T M, Goa K L. Cilostazol: a review of its use in intermittent claudication. Am J Cardiovasc Drugs: 2003; 3 117 138
-
(2003)
Am J Cardiovasc Drugs
, vol.3
, pp. 117-138
-
-
Chapman, T.M.1
Goa, K.L.2
-
107
-
-
0036786624
-
New mechanism of action for cilostazol: Interplay between adenosine and cilostazol in inhibiting platelet activation
-
Sun B, Le S N, Lin S, Fong M, Guertin M, Liu Y, Tandon N N, Yoshitake M, Kambayashi J-I. New mechanism of action for cilostazol: interplay between adenosine and cilostazol in inhibiting platelet activation. J Cardiovasc Pharmacol: 2002; 40 577 585
-
(2002)
J Cardiovasc Pharmacol
, vol.40
, pp. 577-585
-
-
Sun, B.1
Le, S.N.2
Lin, S.3
Fong, M.4
Guertin, M.5
Liu, Y.6
Tandon, N.N.7
Yoshitake, M.8
Kambayashi, J.-I.9
-
108
-
-
0034770840
-
Interplay between inhibition of adenosine uptake and phosphodiesterase type 3 on cardiac function by cilostazol, an agent to treat intermittent claudication
-
Wang S, Cone J, Fong M, Yoshitake M, Kambayashi Ji, Liu Y. Interplay between inhibition of adenosine uptake and phosphodiesterase type 3 on cardiac function by cilostazol, an agent to treat intermittent claudication. J Cardiovasc Pharmacol: 2001; 38 775 783
-
(2001)
J Cardiovasc Pharmacol
, vol.38
, pp. 775-783
-
-
Wang, S.1
Cone, J.2
Fong, M.3
Yoshitake, M.4
Kambayashi, J.5
Liu, Y.6
-
109
-
-
0036999131
-
Comparison of the effects of cilostazol and milrinone on cAMP-PDE activity, intracellular cAMP and calcium in the heart
-
Shakur Y, Fong M, Hensley J, Cone J, Movsesian M A, Kambayashi J-I, Yoshitake M, Liu Y. Comparison of the effects of cilostazol and milrinone on cAMP-PDE activity, intracellular cAMP and calcium in the heart. Cardiovasc Drugs Ther: 2002; 16 417 427
-
(2002)
Cardiovasc Drugs Ther
, vol.16
, pp. 417-427
-
-
Shakur, Y.1
Fong, M.2
Hensley, J.3
Cone, J.4
Movsesian, M.A.5
Kambayashi, J.-I.6
Yoshitake, M.7
Liu, Y.8
-
110
-
-
36349033482
-
Phosphodiesterase type 5: Expanding roles in cardiovascular regulation
-
Kass D A, Champion H C, Beavo J A. Phosphodiesterase type 5: expanding roles in cardiovascular regulation. Circ Res: 2007; 101 1084 1095
-
(2007)
Circ Res
, vol.101
, pp. 1084-1095
-
-
Kass, D.A.1
Champion, H.C.2
Beavo, J.A.3
-
111
-
-
76649142776
-
Phosphodiesterase Inhibitors for Pulmonary Hypertension
-
Bergot E, Magnier R, Zalcman G. Phosphodiesterase Inhibitors for Pulmonary Hypertension. N Eng J Med: 2010; 362 559 560
-
(2010)
N Eng J Med
, vol.362
, pp. 559-560
-
-
Bergot, E.1
Magnier, R.2
Zalcman, G.3
-
112
-
-
79551580284
-
PDE5 Inhibition with Sildenafil Improves Left Ventricular Diastolic Function, Cardiac Geometry, and Clinical Status in Patients with Stable Systolic Heart Failure/Clinical Perspective
-
Guazzi M, Vicenzi M, Arena R, Guazzi M D. PDE5 Inhibition With Sildenafil Improves Left Ventricular Diastolic Function, Cardiac Geometry, and Clinical Status in Patients With Stable Systolic Heart Failure/Clinical Perspective. Circulation: Heart Fail: 2011; 4 8 17
-
(2011)
Circulation: Heart Fail
, vol.4
, pp. 8-17
-
-
Guazzi, M.1
Vicenzi, M.2
Arena, R.3
Guazzi, M.D.4
-
113
-
-
84861234413
-
Chronic Inhibition of Cyclic GMP Phosphodiesterase 5A Improves Diabetic Cardiomyopathy: A Randomized, Controlled Clinical Trial Using Magnetic Resonance Imaging with Myocardial Tagging
-
Giannetta E, Isidori A M, Galea N, Carbone I, Mandosi E, Vizza C D, Naro F, Morano S, Fedele F, Lenzi A. Chronic Inhibition of Cyclic GMP Phosphodiesterase 5A Improves Diabetic Cardiomyopathy: A Randomized, Controlled Clinical Trial Using Magnetic Resonance Imaging with Myocardial Tagging. Circulation: 2012; 125 2323 2333
-
(2012)
Circulation
, vol.125
, pp. 2323-2333
-
-
Giannetta, E.1
Isidori, A.M.2
Galea, N.3
Carbone, I.4
Mandosi, E.5
Vizza, C.D.6
Naro, F.7
Morano, S.8
Fedele, F.9
Lenzi, A.10
-
114
-
-
0034213608
-
Hemodynamic effects of sildenafil in men with severe coronary artery disease
-
Herrmann H C, Chang G, Klugherz B D, Mahoney P D. Hemodynamic effects of sildenafil in men with severe coronary artery disease. N Engl J Med: 2000; 342 1622 1626
-
(2000)
N Engl J Med
, vol.342
, pp. 1622-1626
-
-
Herrmann, H.C.1
Chang, G.2
Klugherz, B.D.3
Mahoney, P.D.4
-
115
-
-
80051545460
-
Effect of Phosphodiesterase Type 5 Inhibition on Microvascular Coronary Dysfunction in Women: A Women's Ischemia Syndrome Evaluation (WISE) Ancillary Study
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Denardo S J, Wen X, Handberg E M, Bairey Merz C N, Sopko G S, Cooper-Dehoff R M, Pepine C J. Effect of Phosphodiesterase Type 5 Inhibition on Microvascular Coronary Dysfunction in Women: A Women's Ischemia Syndrome Evaluation (WISE) Ancillary Study. Clin Cardiol: 2011; 34 483 487
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(2011)
Clin Cardiol
, vol.34
, pp. 483-487
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Denardo, S.J.1
Wen, X.2
Handberg, E.M.3
Bairey Merz, C.N.4
Sopko, G.S.5
Cooper-Dehoff, R.M.6
Pepine, C.J.7
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