Interventional effect of valsartan on expression of inducible cAMP early repressor and phosphodiesterase 3A in rats after myocardial infarction

European Journal of Pharmacology

Volumn 602, Issue 2-3, 2009, Pages 348-354

  Ma, Dan ^a   Fu, Lu ^a   Shen, Jingxia ^a   Zhou, Ping ^a   Gao, Yufei ^b   Xie, Rongsheng ^a   Li, Yuanshi ^a   Han, Ying ^a   Wang, Yumei ^a   Wang, Fei ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b HEILONGJIANG PROVINCIAL HOSPITAL   (China)

Author keywords

cAMP response element binding protein; Inducible cAMP early repressor; Myocardial infarction; Phosphodiesterase 3A; Valsartan

Indexed keywords

CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA; PHOSPHODIESTERASE III; PROTEIN BCL 2; VALSARTAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ECHOCARDIOGRAPHY; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE CELL; HEART VENTRICLE REMODELING; HEMODYNAMICS; IMMUNOBLOTTING; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ANIMALS; APOPTOSIS; CARDIOMEGALY; CYCLIC AMP RESPONSE ELEMENT MODULATOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 3; GENE EXPRESSION REGULATION; HEART; HEART FAILURE; MYOCARDIAL INFARCTION; MYOCARDIUM; RATS; RECEPTORS, ANGIOTENSIN; TETRAZOLES; VALINE; VENTRICULAR REMODELING;

EID: 58149164894     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.11.002     Document Type: Article

References (24)

1. Cohn J.N., Bristow M.R., Chien K.R., Colucci W.S., Frazier O.H., Leinwand L.A., Lorell B.H., Moss A.J., Sonnenblick E.H., Walsh R.A., Mockrin S.C., and Reinlib L. Report of the National Heart, Lung, and Blood Institute Special Emphasis Panel on Heart Failure Research. Circulation 95 (1997) 766-770
2. Daniels M.C., Keller R.S., and de Tombe P.P. Losartan prevents contractile dysfunction in rat myocardium after left ventricular myocardial infarction. Am. J. Physiol, Heart Circ. Physiol. 281 (2001) H2150-2158
3. Danzi S., Ojamaa K., and Klein I. Triiodothyronine-mediated myosin heavy chain gene transcription in the heart. Am. J. Physiol, Heart Circ. Physiol. 284 (2003) H2255-2262
4. Ding B., Abe J., Wei H., Huang Q., Walsh R.A., Molina C.A., Zhao A., Sadoshima J., Blaxall B.C., Berk B.C., and Yan C. Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure. Circulation 111 (2005) 2469-2476
5. Ding B., Abe J., Wei H., Xu H., Che W., Aizawa T., Liu W., Molina C.A., Sadoshima J., Blaxall B.C., Berk B.C., and Yan C. A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis. Proc. Natl. Acad. Sci. USA 102 (2005) 14771-14776
6. Fentzke R.C., Korcarz C.E., Lang R.M., Lin H., and Leiden J.M. Dilated cardiomyopathy in transgenic mice expressing a dominant-negative CREB transcription factor in the heart. J. Clin. Invest. 101 (1998) 2415-2426
7. Gervais M., Richer C., Fornes P., De Gasparo M., and Giudicelli J.F. Valsartan and coronary haemodynamics in early post-myocardial infarction in rats. Fundam. Clin. Pharmacol. 13 (1999) 635-645
8. Gurevich A.K., Falk S.A., Nemenoff R.A., Weinberger H.D., Summer S.N., Rizeq M., Gengaro P.E., Bedigian M.P., and Schrier R.W. Effects of angiotensin receptor blockade on haemodynamics and gene expression after myocardial infarction. Drugs R&D 3 (2002) 239-249
9. Jaworski J., Mioduszewska B., Sanchez-Capelo A., Figiel I., Habas A., Gozdz A., Proszynski T., Hetman M., Mallet J., and Kaczmarek L. Inducible cAMP early repressor, an endogenous antagonist of cAMP responsive element-binding protein, evokes neuronal apoptosis in vitro. J. Neurosci. 23 (2003) 4519-4526
10. Kato K., Yin H., Agata J., Yoshida H., Chao L., and Chao J. Adrenomedullin gene delivery attenuates myocardial infarction and apoptosis after ischemia and reperfusion. Am. J. Physiol, Heart Circ. Physiol. 285 (2003) H1506-1514
11. Kim S., Yoshiyama M., Izumi Y., Kawano H., Kimoto M., Zhan Y., and Iwao H. Effects of combination of ACE inhibitor and angiotensin receptor blocker on cardiac remodeling, cardiac function, and survival in rat heart failure. Circulation 103 (2001) 148-154
12. Lenfant C. Fixing the failing heart. Circulation 95 (1997) 771-772
13. McMurray J., Solomon S., Pieper K., Reed S., Rouleau J., Velazquez E., White H., Howlett J., Swedberg K., Maggioni A., Kober L., Van de Werf F., Califf R., and Pfeffer M. The effect of valsartan, captopril, or both on atherosclerotic events after acute myocardial infarction: an analysis of the Valsartan in Acute Myocardial Infarction Trial (VALIANT). J. Am. Coll. Cardiol. 47 (2006) 726-733
14. Mioduszewska B., Jaworski J., and Kaczmarek L. Inducible cAMP early repressor (ICER) in the nervous system - a transcriptional regulator of neuronal plasticity and programmed cell death. J. Neurochem. 87 (2003) 1313-1320
15. Nishihara H., Hwang M., Kizaka-Kondoh S., Eckmann L., and Insel P.A. Cyclic AMP promotes cAMP-responsive element-binding protein-dependent induction of cellular inhibitor of apoptosis protein-2 and suppresses apoptosis of colon cancer cells through ERK1/2 and p38 MAPK. J. Biol. Chem. 279 (2004) 26176-26183
16. Nony P., Boissel J.P., Lievre M., Leizorovicz A., Haugh M.C., Fareh S., and de Breyne B. Evaluation of the effect of phosphodiesterase inhibitors on mortality in chronic heart failure patients. A meta-analysis. Eur. J. Clin. Pharmacol. 46 (1994) 191-196
17. Packer M., Carver J.R., Rodeheffer R.J., Ivanhoe R.J., DiBianco R., Zeldis S.M., Hendrix G.H., Bommer W.J., Elkayam U., and Kukin M.L. Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group. N. Engl. J. Med. 325 (1991) 1468-1475
18. Schieffer B., Wirger A., Meybrunn M., Seitz S., Holtz J., Riede U.N., and Drexler H. Comparative effects of chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade on cardiac remodeling after myocardial infarction in the rat. Circulation 89 (1994) 2273-2282
19. Shakur Y., Holst L.S., Landstrom T.R., Movsesian M., Degerman E., and Manganiello V. Regulation and function of the cyclic nucleotide phosphodiesterase (PDE3) gene family. Prog. Nucleic Acid Res. Mol. Biol. 66 (2001) 241-277
20. Sladek T., Sladkova J., Kolar F., Papousek F., Cicutti N., Korecky B., and Rakusan K. The effect of AT1 receptor antagonist on chronic cardiac response to coronary artery ligation in rats. Cardiovasc. Res. 31 (1996) 568-576
21. Thai H., Guarraia D., Johnson N., Goldman S., and Gaballa M.A. Valsartan therapy in heart failure after myocardial infarction: the role of endothelial dependent vasorelaxation. J. Cardiovasc. Pharmacol. 50 (2007) 703-707
22. Tomita H., Nazmy M., Kajimoto K., Yehia G., Molina C.A., and Sadoshima J. Inducible cAMP early repressor (ICER) is a negative-feedback regulator of cardiac hypertrophy and an important mediator of cardiac myocyte apoptosis in response to beta-adrenergic receptor stimulation. Circ. Res. 93 (2003) 12-22
23. Ventura C., Pintus G., Fiori M.G., Bennardini F., Pinna G., and Gaspa L. Opioid peptide gene expression in the primary hereditary cardiomyopathy of the Syrian hamster. I. Regulation of prodynorphin gene expression by nuclear protein kinase C. J. Biol. Chem. 272 (1997) 6685-6692
24. Wang X., and Dhalla N.S. Modification of beta-adrenoceptor signal transduction pathway by genetic manipulation and heart failure. Mol. Cell. Biochem. 214 (2000) 131-155