Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice

Cellular Signalling

Volumn 19, Issue 8, 2007, Pages 1765-1771

  Sun, Bing ^a   Li, Haiquan ^a   Shakur, Yasmin ^a   Hensley, James ^a   Hockman, Steve ^b   Kambayashi, Junichi ^a   Manganiello, Vincent C ^b   Liu, Yongge ^a  

^a OTSUKA PHARMACEUTICAL DEVELOPMENT AND COMMERCIALIZATION INC   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Heart; PDE3A; PDE3B; Phosphodiesterase; Platelet

Indexed keywords

CILOSTAMIDE; CYCLIC AMP; ISOPRENALINE; PHOSPHODIESTERASE III; PHOSPHODIESTERASE III A; PHOSPHODIESTERASE III B; PROSTAGLANDIN E1; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CARDIOVASCULAR FUNCTION; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART RATE; HEART VENTRICLE CONTRACTION; KNOCKOUT MOUSE; LUNG EMBOLISM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; RECEPTOR SENSITIVITY; SPECIES COMPARISON; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; THROMBOCYTE RICH PLASMA; WILD TYPE;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; BLOOD PLATELETS; CYCLIC AMP; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MICE; MICE, KNOCKOUT; MYOCARDIUM; PLATELET AGGREGATION; PLATELET-RICH PLASMA;

MUS;

EID: 34250615897     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2007.03.012     Document Type: Article

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