Role of the cAMP-binding protein Epac in cardiovascular physiology and pathophysiology

Pflugers Archiv European Journal of Physiology

Volumn 459, Issue 4, 2010, Pages 535-546

  Métrich, Mélanie ^a,b   Berthouze, Magali ^a,b   Morel, Eric ^a,b   Crozatier, Bertrand ^a,b   Gomez, Ana Maria ^c,d   Lezoualc'h, Frank ^a,b  

^a Universite Paris Sud   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c INSERM   (France)

^d UNIV MONTPELLIER   (France)

Author keywords

Calcium; CAMP signaling; Guanine nucleotide exchange factors; Remodeling

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; BETA ADRENERGIC RECEPTOR; CALCIUM CHANNEL L TYPE; CALCIUM ION; CONNEXIN 43; CONNEXIN 45; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DNA DEPENDENT PROTEIN KINASE; EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CAMP; EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CAMP 1; EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CAMP 2; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INTERLEUKIN 6; PROTEIN EPAC; PROTEIN EPAC1; PROTEIN EPAC2; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANTIINFLAMMATORY ACTIVITY; BETA ADRENERGIC STIMULATION; BINDING AFFINITY; BLOOD VESSEL PERMEABILITY; CALCIUM CURRENT; CALCIUM TRANSPORT; CARDIOVASCULAR SYSTEM; CELL COMMUNICATION; CELL MIGRATION; EXCITATION CONTRACTION COUPLING; HEART ARRHYTHMIA; HEART ELECTROPHYSIOLOGY; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE STEADY POTENTIAL; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; HUMAN; LEUKOCYTE MIGRATION; MICROTUBULE; NONHUMAN; PATHOPHYSIOLOGY; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; RESTENOSIS; REVIEW; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

ANIMALS; CARDIOVASCULAR DISEASES; CARDIOVASCULAR PHYSIOLOGICAL PHENOMENA; CELL COMMUNICATION; CELL MOVEMENT; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FIBROSIS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEART CONDUCTION SYSTEM; HYPERTROPHY; MUSCLE, SMOOTH, VASCULAR; MYOCARDIUM; MYOCYTES, SMOOTH MUSCLE; SIGNAL TRANSDUCTION;

EID: 77950930736     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-009-0747-y     Document Type: Review

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