Comparative computational modeling of airflows and vapor dosimetry in the respiratory tracts of rat, monkey, and human

Toxicological Sciences

Volumn 128, Issue 2, 2012, Pages 500-516

  Corley, Richard A ^a   Kabilan, Senthil ^a   Kuprat, Andrew P ^a   Carson, James P ^a   Minard, Kevin R ^a   Jacob, Richard E ^a   Timchalk, Charles ^a   Glenny, Robb ^b   Pipavath, Sudhakar ^b   Cox, Timothy ^b   Wallis, Christopher D ^c   Larson, Richard F ^c   Fanucchi, Michelle V ^d   Postlethwait, Edward M ^d   Einstein, Daniel R ^a  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Acrolein; CFD; PBPK; Respiratory airflows; Respiratory dosimetry

Indexed keywords

ACROLEIN;

AGED; AIRBORNE PARTICLE; AIRFLOW; ANATOMICAL CONCEPTS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CASE REPORT; COMPUTATIONAL FLUID DYNAMICS; DOSIMETRY; FEMALE; GEOMETRY; HAPLORHINI; HUMAN; INHALATION; MALE; MATHEMATICAL MODEL; MOUTH BREATHING; NONHUMAN; NOSE BREATHING; PARTITION COEFFICIENT; RESPIRATORY AIRFLOW; RESPIRATORY SYSTEM; SPECIES DIFFERENCE; STEADY STATE; THICKNESS; TISSUE SPECIFICITY; TRACHEOBRONCHIAL TREE; TRANSPORT KINETICS; VAPOR;

ACROLEIN; AGED; AGED, 80 AND OVER; ANIMALS; FEMALE; HUMANS; MACACA MULATTA; MALE; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY PHYSIOLOGICAL PHENOMENA; TISSUE DISTRIBUTION;

EID: 84865357678     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs168     Document Type: Article

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