Visualizing flow partitioning in a model of the upper human lung airways

Journal of Biomechanical Engineering

Volumn 132, Issue 3, 2010, Pages

  Bauer, K ^a   Chaves, H ^a   Brucker Ch ^a  

^a TU BERGAKADEMIE FREIBERG   (Germany)

Author keywords

Flow partitioning; High frequency oscillatory ventilation (HFOV); In vitro model; Lung airways; Mass transport; Respiratory flow

Indexed keywords

FLOW PARTITIONING; HIGH FREQUENCY; IN-VITRO; LUNG AIRWAYS; MASS TRANSPORT; RESPIRATORY FLOW;

BIOLOGICAL ORGANS; MASS TRANSFER; PROBABILITY DISTRIBUTIONS; REYNOLDS NUMBER; VENTILATION;

TRANSPORT PROPERTIES;

ADVECTION; ARTICLE; CAMERA; FLUID TRANSPORT; HIGH FREQUENCY VENTILATION; HUMAN; LUNG MODEL; OSCILLATION; RESPIRATORY AIRFLOW; TRACHEOBRONCHIAL TREE; UPPER RESPIRATORY TRACT; ANIMAL; BIOLOGICAL MODEL; BIOLOGICAL RHYTHM; BREATHING MECHANICS; COMPUTER SIMULATION; LUNG; LUNG GAS EXCHANGE; PHYSIOLOGY;

ANIMALS; BIOLOGICAL CLOCKS; COMPUTER SIMULATION; HUMANS; LUNG; MODELS, BIOLOGICAL; PULMONARY GAS EXCHANGE; RESPIRATORY MECHANICS;

EID: 77955101980     PISSN: 01480731     EISSN: 15288951     Source Type: Journal    
DOI: 10.1115/1.4000871     Document Type: Article

References (28)

1. Fuhrman, T., 1993, "Pulmonary Barotrauma in Mechanical Ventilation," Chest, 104(3), p. 987.
2. Dreyfuss, D., and Saumon, G., 1993, "Role of Tidal Volume, FRC and End-Inspiratory Volume in the Developement of Pulmonary Edema Following Mechanical Ventilation," Am. Rev. Respir. Dis., 148, pp. 1194-1203. (Pubitemid 23326013)
3. Weibel, E. R., 1963, Morphometry of the Human Lung, Academic, New York.
4. Krishnan, J. A., and Brower, R. G., 2000, "High-Frequency Ventilation for Acute Lung Injury and ARDS," Chest, 118, pp. 795-807.
5. Mochizuki, S., Togashi, Y., Murata, A., and Yang, W. J., 2001, "Visualization Experiment of Mass Transport in Pulmonary Ventilation Inside Bronchial Tube Model," J. Mech. Med. Biol., 1(2), pp. 181-192.
6. Haselton, F. R., and Scherer, P. W., 1982, "Flow Visualization of Steady Streaming in Oscillatory Flow Through a Bifurcating Tube," J. Fluid Mech., 123, pp. 315-333.
7. Schroter, R. C., and Sudlow, M. F., 1969, "Flow Patterns in Models of the Bronchial Airways," Respir. Physiol., 7, pp. 341-355.
8. Dean, W. R., 1927, "Note on the Motion of Fluid in a Curved Pipe," Philos. Mag., 4(7), pp. 208-223.
9. Pedley, T. J., 1977, "Pulmonary Fluid Dynamics," Annu. Rev. Fluid Mech., 9, pp. 229-274.
10. Drazen, J. M., Kamm, R. D., and Slutsky, A. S., 1984, "High-Frequency Ventilation," Physiol. Rev., 64(2), pp. 505-553.
11. Fresconi F. E., and Prasad A. K., 2008, "Convective Dispersion During Steady Flow in the Conducting Airways of the Human Lung," ASME J. Biomech. Eng., 130(1), p. 011015.
12. Ultman, J. S., Shaw, R. G., Fabiano, D. C., and Cooke, K. A., 1988, "Pendelluft and Mixing in a Single Bifurcation Lung Model During High-Frequency Oscillation," J. Appl. Physiol., 65(1), pp. 146-155.
13. Lee, W. J., Kawahashi, M., and Hirahara, H., 2006, "Experimental Analysis of Pendelluft Flow Generated by HFOV in a Human Airway Model," Physiol. Meas., 27, pp. 661-674.
14. Carlon, G. C., Kahn, R. C., Howland, W. S., Ray, C., Jr., Klain, M., and Turnbull, A. D., 1981, "Clinical Experience With High Frequency Jet Ventilation," Crit. Care Med., 9, pp. 1-6.
15. Brücker, Ch., and Riethmuller, M. L., 1998, "Cyclic Flow Oscillations in a System of Repeatedly Branching Channels," Phys. Fluids, 10, pp. 877-885. (Pubitemid 128613776)
16. Horsfield, K., Dart, G., Olsen, D. E., Filley, G. F., and Cumming, G., 1971, "Models of the Human Bronchial Tree," J. Appl. Physiol., 31(2), pp. 207-217.
17. Melling, A., 1997, "Tracer Particles and Seeding for Particle Image Velocimetry," Meas. Sci. Technol., 8(12), pp. 1406-1416.
18. Dring, R. P., 1982, "Sizing Criteria for Laser Anemometry Particles," ASME J. Fluids Eng., 104, pp. 15-17.
19. Snyder, B., Dantzker, D. R., and Jaeger, M. J., 1981, "Flow Partitioning in Symmetric Cascades of Branches," J. Appl. Physiol., 51, pp. 598-606.
20. Fang, C. P., Cohen, B. S., and Lipmann, M., 1992, "Aerosol Tracer Study of Gas Convective-Transport to 0.1 cm Airways by High-Frequency Ventilation in a Human Lung Airway Cast," Exp. Lung Res., 18, pp. 615-632.
21. Tarbell, J. M., Ultmann, J. S., and Durlofsky, L., 1982, "Oscillatory Convective Dispersion in a Branching Tube Network," ASME J. Biomech. Eng., 104, pp. 338-342.
22. Adler, K., and Brücker, Ch., 2007, "Dynamic Flow in a Realistic Model of the Upper Human Lung Airways," Exp. Fluids, 43(2-3), pp. 411-423.
23. Eckmann, D. M., and Grotberg, J. B., 1988, "Oscillatory Flow and Mass Transport in a Curved Tube," J. Fluid Mech., 188, pp. 509-527.
24. Elad, D., Shochat, A., and Shiner, R. J., 1998, "Computational Model of Oscillatory Airflow in a Bronchial Bifurcation," Respir. Physiol., 112, pp. 95-111. (Pubitemid 28274505)
25. Bauer, K., and Bruecker, Ch., 2009, "The Role of Ventilation Frequency in Airways Reopening," J. Biomech., 42, pp. 1108-1113.
26. Lin, C. L., Tawhai, M. H., McLennan, G., and Hoffman, E. A., 2007, "Characteristics of the Turbulent Laryngeal Jet and Its Effect on Airflow in the Human Intra-Thoracic Airways," Respir. Physiol. Neurbiol., 157, pp. 295-309.
27. Luo, H. Y., and Liu, Y., 2008, "Modeling the Bifurcating Flow in a CT-Scanned Human Lung Airway," J. Biomech., 41, pp. 2681-2688.
28. Xi, J., Longest, P. W., and Martonen, T. B., 2008, "Effects of the Laryngeal Jet on Nano- and Microparticle Transport and Deposition in an Approximate Model of the Upper Tracheobronchial Airways," J. Appl. Physiol., 104, pp. 1761-1777.