Application of physiological computational fluid dynamics models to predict interspecies nasal dosimetry of inhaled acrolein

Inhalation Toxicology

Volumn 20, Issue 3, 2008, Pages 227-243

  Schroeter, Jeffry D ^a   Kimbell, Julia S ^a   Gross, Elizabeth A ^a   Willson, Gabrielle A ^b   Dorman, David C ^a   Tan, Yu Mei ^a   Clewell III, Harvey J ^a  

^a HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^b EXPERIMENTAL PATHOLOGY LABORATORIES INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACROLEIN; ALDEHYDE;

AIRFLOW; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW; COMPUTATIONAL FLUID DYNAMICS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIFFUSION; DOSIMETRY; EPITHELIUM HYPERPLASIA; EXPOSURE; FLOW RATE; HUMAN; INFLAMMATION; INHALATION TEST; KINETICS; METABOLISM; NONHUMAN; NOSE CAVITY; NOSE INJURY; NOSE IRRITATION; OLFACTORY EPITHELIUM; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RESPIRATORY EPITHELIUM; SPECIES COMPARISON; SQUAMOUS CELL METAPLASIA; STEADY STATE; THREE DIMENSIONAL IMAGING; TISSUE REACTION; UPPER RESPIRATORY TRACT;

ACROLEIN; AIR POLLUTANTS; ANIMALS; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INHALATION EXPOSURE; MODELS, BIOLOGICAL; NASAL CAVITY; NASAL MUCOSA; RATS;

ANIMALIA; RATTUS; RODENTIA;

EID: 40049094331     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.1080/08958370701864235     Document Type: Article

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